Gene

KWMTBOMO05209  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002460

Annotation

PREDICTED:_exosome_complex_exonuclease_RRP44_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr9(+):11066745-11082307      View in EpiBrowser

Full name

DNA helicase      

Location in the cell

Nuclear   Reliability : 2.715

CDS

ATGTGGACTACAAAAACCTTTCTTACCAAAACTAAGCGTGGTAACATATTGAAGATTGTAAGAGAACATTACTTGCGTGACGATTTATTGTGCGGATCTGCAGCATGTAACACATGTCCACACAAAGATGATGAATTGGTATTGGAGACCTCTCCCGATTCTCCATGTGCTTTGTTCGATTTCCCACATTATCTAGTATTGGATACTAATGTTGTGTTACATCAAATAGATGTTTTGGAGGAAGATGCTTTGACTAATGTTATCATTTTACAAACTGTACTTGAGGAAGTGAAACATCAAAATACTGCAGTTTTCCAGAGATTGCTGGATATAATTTCCAACAAAAAGAGAAAGTTTTATTCATTTGTTAATGAACATCACAAGGATACCTATATAGAGCGCTCACCGGGTGAGAAACAAAATGATAGGAATGACAGATCTATACGTAAAGCAACATCTTGGTACGAATATCACTTGAGCATAAATAGCCTTGATGGAAAATTCCCAAAGATAATATTGGTGACGGATGATGAAAATAATCGAAAGCTTGCCCAAGAAGATGGCATTATTTGTTGTTCAATTAAAGATTACATAGAAAACGTATCTGGATTTGTTGGTTTAGTGGATAAACTATCTAAGAATGTAATGCCTGAAACATGCTCTAAAGATGCATTATACCCTGCACATTTAACTCCATCACAAATACATGAGGGGATCCGCTGTGGCCAACTGTATCAAGGCACATATCATGCTTCTAGAGAAAATTTCTTGGAAGGAAATGCCAGTGTTAATGGTTTTGAAAAGTCGATATTATTGCAAGGTCACATAGGCATAAACCGTGCTATAGATGGTGATATAGTTGCGATAGAAATTTTCCCTAAAGAAGAATGGCGGAAACCTAGTAATATAGTTCTAGAGGATAAAACTGAGGACCCTGAAAATATTTTAGAAGAAGAGACTGTTTTGCTTGATGCTGCAAAACCAGTAGATAATGATGACGAAATCACCCCTACAGGAAAAGTAGTAGGGATAATTAGAAGGAAATGGAGACAATATTGTGGAATTCTAATGCCTAGTAAATTTCATGGTGCAACACGTCATCTCTTCACACCAGCGGAGAAGAGAATTCCTCGTGTTCGTATCGAAACCAGACAGAGTGAAATACTGGCCTCGCAACGCATTTTGGTTGCTCTTGACTCTTGGCCCAGGAACAGCCGATATCCACTTGGACATCTTGTAAGAGCACTCGGGCCAATTGGTGACAAGGATGCAGAAAACGAGGTCATACTGCTAGAGCACGACGTTCCTCACGCGAGATTCAGCGAAGCCGTACTCAACTGTCTACCGCCCAACGATTGGACTATACCTGAAGAGGAAAGGCAGAAACGTGTAGATCTACGCGACGTGTGCGTATGTTCCGTGGATCCGCCCGGGTGCACGGACATAGACGACGCGCTGCACGCCCGCAGGCTGGGCTCCAGCGACGGGCTCGCGACCTACGAAGTGGGCGTGCACATCGCTGACGTCACGTACTTCGTGAAGCCCGACACCGCCCTGGACAAGGAGGCCGCTTCGAGGTCAACTACAGTATATCTCGTCGACAGGAGGATCGATATGGTGCCGGAGTTACTTAGCTCGAACCTGTGCTCACTTAGAGGCGGCGAAGAAAGGCTCGCCTTCTCGTGCGTGTGGGAGATGGACGAGAACGCTAATGTCTTGTCTACGAAATTCCACAAAAGTATCATAAAGTCAAAAGCTGCGATGACTTACGAAGAGGCTCAGATCGCAATCGACGATTCGAGTCGCAAAGACGAGATAGCGAAATCTCTGCGCGTACTCAACAAACTCGCTAAGAAACTTAAGAAAAAGCGATTGGACAGTGGGGCCCTGTTACTGGCCTCGCCCGAGATCCGATTTCAGGTAGACTCTGAGACTCACGACCCAATCGAAGTGCAAGCCAAGAAGATAGTTGACACTAACTCAATGGTAGAAGAATTCATGTTGTTAGCCAATACCAGCGTGGCTCAGAAGATTCTAGAAGAATTCCCTCAATGTGCCATGTTGCGGAGACACCCGGCGCCGCCTCCTGCTAATTTTGATACTTTCTTAAAAGCTGCGAGACAACAGGGCTTCGAAATCGACGTGTCAACGAACAAATCGTTTTCGAAATCGCTGAACGAGGCCGTGATACCGGAGCGGCCGTTCTTCAACACGCTGCTGCGCATAATGGCGACGCGCTGCATGCAGCAGGCCGCGTACTTCGTGAGCGGGAGCCTCGCCGCCGACCACTACTACCACTACGGACTGGCCTGTCCCATCTACACGCACTTCACCTCGCCCATACGGAGGTACGCGGACGTGGTGGTGCACCGGCTGCTGGCGGCGAGCGTGGCGGGGGCGGGCCCGCACGCCGCGCTGCTGGACGCGCGCCGCCAGGCCGCGCTCGCCGACACACTCAACTACCGGCACCGCCACGCGCAGCTCGCCGGCCGCGCCTCCGTGGCGCTCAACACTCACATTTTATTCAAGAACAGAGTAGAAATAGAGTCTGCAGTTGTACTGGCTGTGAAGCGGAACGCCCTGCAAGTATTGATACCTAAATATGGACTGGAAGGACCTCTGTATTTACCATCTGAAAAATTCACGTATAATGAAGAGGAACACGTTCAGAAATGCGGGGACGTCGTGCTGAAAACGTTCGACGAGCTAACGGTCCGTCTCAGCTTGGACAGCTCGAATCTTCAGCACAGGAAGCTCGTGTTCGAGCTGGTCGAGCCGCACGTGCCCGGCTTCAGCTACGTGCCGGACGCGGGGAACATGGAAGTCGACGACGTCGCAGACACCGCAGCGCCAAGCTCGGAAAAGACTCACAAGAAGAGAGAGATCCCAGCCGCCGCTGCCCCGAAACCCAGTAAAAAGAGGAAATCCAGAAGGAAATGA

Protein

MWTTKTFLTKTKRGNILKIVREHYLRDDLLCGSAACNTCPHKDDELVLETSPDSPCALFDFPHYLVLDTNVVLHQIDVLEEDALTNVIILQTVLEEVKHQNTAVFQRLLDIISNKKRKFYSFVNEHHKDTYIERSPGEKQNDRNDRSIRKATSWYEYHLSINSLDGKFPKIILVTDDENNRKLAQEDGIICCSIKDYIENVSGFVGLVDKLSKNVMPETCSKDALYPAHLTPSQIHEGIRCGQLYQGTYHASRENFLEGNASVNGFEKSILLQGHIGINRAIDGDIVAIEIFPKEEWRKPSNIVLEDKTEDPENILEEETVLLDAAKPVDNDDEITPTGKVVGIIRRKWRQYCGILMPSKFHGATRHLFTPAEKRIPRVRIETRQSEILASQRILVALDSWPRNSRYPLGHLVRALGPIGDKDAENEVILLEHDVPHARFSEAVLNCLPPNDWTIPEEERQKRVDLRDVCVCSVDPPGCTDIDDALHARRLGSSDGLATYEVGVHIADVTYFVKPDTALDKEAASRSTTVYLVDRRIDMVPELLSSNLCSLRGGEERLAFSCVWEMDENANVLSTKFHKSIIKSKAAMTYEEAQIAIDDSSRKDEIAKSLRVLNKLAKKLKKKRLDSGALLLASPEIRFQVDSETHDPIEVQAKKIVDTNSMVEEFMLLANTSVAQKILEEFPQCAMLRRHPAPPPANFDTFLKAARQQGFEIDVSTNKSFSKSLNEAVIPERPFFNTLLRIMATRCMQQAAYFVSGSLAADHYYHYGLACPIYTHFTSPIRRYADVVVHRLLAASVAGAGPHAALLDARRQAALADTLNYRHRHAQLAGRASVALNTHILFKNRVEIESAVVLAVKRNALQVLIPKYGLEGPLYLPSEKFTYNEEEHVQKCGDVVLKTFDELTVRLSLDSSNLQHRKLVFELVEPHVPGFSYVPDAGNMEVDDVADTAAPSSEKTHKKREIPAAAAPKPSKKRKSRRK

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Similarity

Belongs to the RNR ribonuclease family.
Belongs to the RuvB family.

Uniprot

A0A2H1WP90   A0A212ESK5   A0A194QHD2   A0A2M4AP33   A0A182MNV9   A0A182KC56   + More
A0A182FXF0   A0A182YLB4   A0A182N1Q5   A0A2J7RBX9   A0A182RX07   A0A182Q2N5   A0A182WAH3   A0A2M4CSQ7   A0A2M4CSG1   A0A182PSF2   A0A084WKT9   Q7Q9K4   A0A182XEX6   A0A182UYB4   A0A182TU70   A0A182HP02   K7J7A8   A0A1B6CFN6   A0A0C9QLM3   A0A182JC98   A0A1A9Y8Y0   A0A1B0BGS5   A0A034W6J3   A0A0A1XHC2   A0A0K8VYD9   A0A1A9WLS7   A0A336KCD1   A0A154PSJ0   A0A1A9V934   A0A1A9ZRQ5   A0A026WIY0   W8BRE5   A0A067RGI4   A0A158NN41   A0A1I8MCR7   A0A3B0JM43   A0A1B0FG21   A0A0L7QU92   A0A0L0C608   B4PVW4   A0A1W4V557   F4X1V9   E2BW43   B3P754   Q960A7   I1WYH0   B4NF36   Q9VC93   B4K9V7   Q297C3   B4LXN5   A0A2J7RBW2   B4GEB4   A0A1S4FUB0   B4HGM4   B3N1N5   A0A0M4EVE1   Q16PB6   B0WA64   A0A2A3ELN9   A0A1I8PBM3   A0A088A151   A0A1Q3EXZ6   R7URV7   A0A195C442   Q9BI20   A0A0M9A0J0   B4JFX3   E9FTY3   A0A195FBZ3   A0A0P5H4F1   A0A164SS59   A0A0P5BGH7   A0A0V0G6Q0   A0A151J5T2   A0A069DZM9   A0A023F503   A0A195BA76   A0A0T6B0T8   A0A224X6Q5   A0A2S2QPA3   E2A2U1   A0A0P5VHX4   A0A1W4XJS8   A0A2H8TFT5   A0A210PZ84   A0A1E1X5G1   B4QT46   A0A2S2P3C3   A0A0P4VTC1   T1IAM3   A0A131XAA4   A0A224YML1   N6TI44  

EC Number

3.6.4.12

Pubmed

22118469    26354079    25244985    24438588    12364791    14747013    + More
17210077    20075255    25348373    25830018    24508170    30249741    24495485    24845553    21347285    25315136    26108605    17994087    17550304    21719571    20798317    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    17510324    23254933    21292972    26334808    25474469    28812685    28503490    27129103    28049606    28797301    23537049   

EMBL

ODYU01010019    SOQ54827.1    AGBW02012778    OWR44459.1    KQ459220    KPJ02851.1    + More
GGFK01009196    MBW42517.1    AXCM01001477    NEVH01005889    PNF38325.1    AXCN02000987    GGFL01004117    MBW68295.1    GGFL01004118    MBW68296.1    ATLV01024147    KE525350    KFB50833.1    AAAB01008900    EAA09476.3    APCN01002823    GEDC01024992    JAS12306.1    GBYB01004449    JAG74216.1    JXJN01013983    JXJN01013984    GAKP01009549    JAC49403.1    GBXI01003916    JAD10376.1    GDHF01008458    JAI43856.1    UFQS01000257    UFQT01000257    SSX02097.1    SSX22474.1    KQ435050    KZC14228.1    KK107182    QOIP01000011    EZA55948.1    RLU16690.1    GAMC01004883    JAC01673.1    KK852482    KDR22892.1    ADTU01021015    OUUW01000007    SPP83305.1    CCAG010016676    KQ414735    KOC62185.1    JRES01000953    KNC26849.1    CM000160    EDW98963.1    GL888553    EGI59568.1    GL451091    EFN80075.1    CH954182    EDV53874.1    AY052150    AAK93574.1    BT133490    AFI71920.1    CH964251    EDW83411.1    AE014297    AAF56281.1    AGB96290.1    CH933806    EDW15605.1    CM000070    EAL28283.2    CH940650    EDW66819.1    PNF38326.1    CH479182    EDW33949.1    CH480815    EDW43477.1    CH902661    EDV34004.1    CP012526    ALC47280.1    CH477788    EAT36222.1    DS231869    EDS40893.1    KZ288215    PBC32675.1    GFDL01014860    JAV20185.1    AMQN01001027    KB298688    ELU08883.1    KQ978344    KYM94946.1    AJ276897    CAC35051.1    KQ435776    KOX74895.1    CH916369    EDV92512.1    GL732524    EFX89559.1    KQ981693    KYN37574.1    GDIQ01232888    JAK18837.1    LRGB01001937    KZS09891.1    GDIP01184968    JAJ38434.1    GECL01002406    JAP03718.1    KQ979935    KYN18591.1    GBGD01000360    JAC88529.1    GBBI01002608    JAC16104.1    KQ976537    KYM81441.1    LJIG01016379    KRT80779.1    GFTR01008310    JAW08116.1    GGMS01010300    MBY79503.1    GL436214    EFN72248.1    GDIP01114733    JAL88981.1    GFXV01001124    MBW12929.1    NEDP02005354    OWF41800.1    GFAC01004686    JAT94502.1    CM000364    EDX14210.1    GGMR01011233    MBY23852.1    GDKW01002400    JAI54195.1    ACPB03000063    ACPB03000064    GEFH01004782    JAP63799.1    GFPF01007712    MAA18858.1    APGK01036956    KB740945    ENN77493.1   

Proteomes

UP000007151    UP000053268    UP000075883    UP000075881    UP000069272    UP000076408    + More
UP000075884    UP000235965    UP000075900    UP000075886    UP000075920    UP000075885    UP000030765    UP000007062    UP000076407    UP000075903    UP000075902    UP000075840    UP000002358    UP000075880    UP000092443    UP000092460    UP000091820    UP000076502    UP000078200    UP000092445    UP000053097    UP000279307    UP000027135    UP000005205    UP000095301    UP000268350    UP000092444    UP000053825    UP000037069    UP000002282    UP000192221    UP000007755    UP000008237    UP000008711    UP000007798    UP000000803    UP000009192    UP000001819    UP000008792    UP000008744    UP000001292    UP000007801    UP000092553    UP000008820    UP000002320    UP000242457    UP000095300    UP000005203    UP000014760    UP000078542    UP000053105    UP000001070    UP000000305    UP000078541    UP000076858    UP000078492    UP000078540    UP000000311    UP000192223    UP000242188    UP000000304    UP000015103    UP000019118   

PRIDE

Q960A7    I1WYH0    Q9VC93    Q9BI20   

Pfam

PF17849   OB_Dis3        + More
PF13638   PIN_4
PF17216   Rrp44_CSD1
PF00773   RNB
PF17215   Rrp44_S1
PF17856   TIP49_C
PF06068   TIP49

Interpro

IPR012340   NA-bd_OB-fold        + More
IPR033771   Rrp44_CSD1       
IPR029060   PIN-like_dom_sf       
IPR041505   Dis3_CSD2       
IPR001900   RNase_II/R       
IPR002716   PIN_dom       
IPR022966   RNase_II/R_CS       
IPR033770   RRP44_S1       
IPR003593   AAA+_ATPase       
IPR041048   RuvB-like_C       
IPR010339   TIP49_P-loop       
IPR027417   P-loop_NTPase       

SUPFAM

SSF50249   SSF50249        + More
SSF88723   SSF88723       
SSF52540   SSF52540       

ProteinModelPortal

A0A2H1WP90   A0A212ESK5   A0A194QHD2   A0A2M4AP33   A0A182MNV9   A0A182KC56   + More
A0A182FXF0   A0A182YLB4   A0A182N1Q5   A0A2J7RBX9   A0A182RX07   A0A182Q2N5   A0A182WAH3   A0A2M4CSQ7   A0A2M4CSG1   A0A182PSF2   A0A084WKT9   Q7Q9K4   A0A182XEX6   A0A182UYB4   A0A182TU70   A0A182HP02   K7J7A8   A0A1B6CFN6   A0A0C9QLM3   A0A182JC98   A0A1A9Y8Y0   A0A1B0BGS5   A0A034W6J3   A0A0A1XHC2   A0A0K8VYD9   A0A1A9WLS7   A0A336KCD1   A0A154PSJ0   A0A1A9V934   A0A1A9ZRQ5   A0A026WIY0   W8BRE5   A0A067RGI4   A0A158NN41   A0A1I8MCR7   A0A3B0JM43   A0A1B0FG21   A0A0L7QU92   A0A0L0C608   B4PVW4   A0A1W4V557   F4X1V9   E2BW43   B3P754   Q960A7   I1WYH0   B4NF36   Q9VC93   B4K9V7   Q297C3   B4LXN5   A0A2J7RBW2   B4GEB4   A0A1S4FUB0   B4HGM4   B3N1N5   A0A0M4EVE1   Q16PB6   B0WA64   A0A2A3ELN9   A0A1I8PBM3   A0A088A151   A0A1Q3EXZ6   R7URV7   A0A195C442   Q9BI20   A0A0M9A0J0   B4JFX3   E9FTY3   A0A195FBZ3   A0A0P5H4F1   A0A164SS59   A0A0P5BGH7   A0A0V0G6Q0   A0A151J5T2   A0A069DZM9   A0A023F503   A0A195BA76   A0A0T6B0T8   A0A224X6Q5   A0A2S2QPA3   E2A2U1   A0A0P5VHX4   A0A1W4XJS8   A0A2H8TFT5   A0A210PZ84   A0A1E1X5G1   B4QT46   A0A2S2P3C3   A0A0P4VTC1   T1IAM3   A0A131XAA4   A0A224YML1   N6TI44  

PDB

6D6R     E-value=0,     Score=2411

KEGG

101744670    K12585 exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] | (RefSeq) exosome complex exonuclease R

PATHWAY

03018    RNA degradation - Bombyx mori (domestic silkworm)

GO

GO:0003723   GO:0004540   GO:0004527   GO:0016075   GO:0000177   GO:0004519   GO:0000176   GO:0000178   GO:0000175   GO:0003678   GO:0005634   GO:0005524   GO:0004521   GO:0004532   GO:0005652   GO:0000278   GO:0010468   GO:0051607   GO:0071027  

Subcellular location

Nucleus  

Length:

979

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.17418

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00016

outside

1  -  979

 

 

Pi

221.377399

Theta

181.768816

Tajima's D

0.601586

CLR

0.36948

CSRT

0.544172791360432

Interpretation

Uncertain