Gene

KWMTBOMO05200

Pre Gene Modal

BGIBMGA002442

Annotation

neuropeptide_receptor_A19_[Bombyx_mori]

Location

Bomo_Chr9(-):10777215-10780485      View in EpiBrowser

Full name

RYamide receptor      

Alternative Name

Neuropeptide Y-like receptor

Location in the cell

PlasmaMembrane   Reliability : 4.933

CDS

ATGTATGAGTCGGAATCGATAGACTTTGATTCTAGTACGCTGTCAGACTTCCTTATACGCAACGTCACATCCAGTGAATACTATATAAATGCTACAGCCTCGTCCAACTTAACGAAACTAGATTACGACGCTATATGCAATCCGAGTACATCCTCAGAGAGCTTCTTTACTTCTGCGACATTCCAAACATGCGTTTATTTCATGTACTGCATCGTTTTTGTTGTGGCACTCGTTGGAAACGGACTAGTCTGCTTCGTTGTACAAACATCGCCTCGGATGAAAACGGTCACAAATTATTTCATAGTAAACCTGGCAGTGGGCGATATCCTGATGACGTTGTTCTGTGTGCCGTTTTCTTTCGTATCAATGCTTGTGCTGCGGTATTGGCCCTTTGGTGGTATTATGTGCAAAGTTGTCAACTTCTCACAAGCGGTTTCAGTGCTCGTGAGCGCATACACTTTACTAGCTATATCGATTGACCGATACATGGCAATAATGCGCCCATTGAAACCTAGGATGGGTAAAACCGCAGCAAAAATGGTTGTCGCTGGCGTGTGGGGAGGTGCTATTGCGACCGCCACCCCTATATACGTAGTATCGAAATTGGAGAGACCTGCAGAGTGGCATAAATACTGTCAACTAGATATTTGCCACGAAGAATGGGACCACGTGGAACAAAGTGAGCGTTACACCTGTGCGCTGTTGGTGCTTCAGTTTGTATTGCCACTTAGCGCTCTTGTGTGTACATATGCTCGCATTGCCCACGTAGTCTGGGGCGGACGACCACCCGGTGAAGCCGAAAGTACAAGAGATTCCAGAATGCAACGATCAAAAAGAAAGATGATCAAAATGATGGTGATTGTTGTAGCAGTATTCACGGTTTGCTGGCTCCCACTGAACATTTTTATTGCAAAAAAGGATGTCACGTTGTCAACTGACGTCAATGGACATAATCGTTTTCAGTTCAAAGCACAAATTAGCAGCTAA

Protein

MYESESIDFDSSTLSDFLIRNVTSSEYYINATASSNLTKLDYDAICNPSTSSESFFTSATFQTCVYFMYCIVFVVALVGNGLVCFVVQTSPRMKTVTNYFIVNLAVGDILMTLFCVPFSFVSMLVLRYWPFGGIMCKVVNFSQAVSVLVSAYTLLAISIDRYMAIMRPLKPRMGKTAAKMVVAGVWGGAIATATPIYVVSKLERPAEWHKYCQLDICHEEWDHVEQSERYTCALLVLQFVLPLSALVCTYARIAHVVWGGRPPGEAESTRDSRMQRSKRKMIKMMVIVVAVFTVCWLPLNIFIAKKDVTLSTDVNGHNRFQFKAQISS

Description

Receptor for the neuropeptides RYamide-1 and RYamide-2 (PubMed:21843505, PubMed:21704020). The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system (PubMed:21843505, PubMed:21704020). RYamide signaling may suppress feeding behavior (PubMed:21704020).

Similarity

Belongs to the G-protein coupled receptor 1 family.

Keywords

Cell membrane   Complete proteome   G-protein coupled receptor   Glycoprotein   Membrane   Receptor   Reference proteome   Transducer   Transmembrane   Transmembrane helix  

Feature

chain  RYamide receptor

Uniprot

B3XXN2   A0A0S1YD83   A0A2H1V2X5   A0A0L7L8U4   A0A0S1YDM6   B3XXN5   + More
A0A194RNG8   A0A2H1VQ84   W8BKX0   W8C5P9   A0A1B6GV51   A0A1B6HNX7   A0A1B6KQU8   U3U7M9   U3U4E6   A0A1A9ZQ06   U5N1G6   B4K9P0   B4M121   A0A0R3NME0   I5ANE3   A0A0U1SQQ4   A0A1B0GFC2   A0A1A9YGR4   B3MT11   A0A1B0BK89   B4N8F0   A0A1A9UTI4   A0A1A9VZB2   A0A3B0K4J6   A0A0R3NFZ1   Q7PS45   A0A154PPP1   A0A1W4UIN3   A0A1W4U5X8   A0A2A3E4P5   A0A310SGV6   A0A087ZXB1   A0A2S2NKP8   P25931   A0A0B4LIR4   A0A2H8TU58   A0A0B4LHT6   J9JLB3   Q2QKU5   U5N1H5   A0A0L7QUK8   A0A1B6DRF1   U5N4G7   Q16Z67   B0XGN8   A0A087UNN0   A0A0P5YRX6   A0A2U9PFU7   E9G455   A0A0N8A9E0   A0A0P6G3P1   A0A147BFV4   T1KC18   A0A0P6HZ76   A0A164Z7G7  

Pubmed

18725956    26227816    26354079    24495485    23932938    24130914    + More
17994087    15632085    18057021    12364791    14747013    17210077    21843505    10731132    12537572    1370455    21704020    12537568    12537573    12537574    16110336    17569856    17569867    17510324    21292972    29652888   

EMBL

AB330440    BAG68418.1    KT031017    ALM88315.1    ODYU01000259    SOQ34722.1    + More
JTDY01002261    KOB71780.1    KT031020    ALM88318.1    AB330443    BAG68421.1    KQ459984    KPJ18959.1    ODYU01003776    SOQ42958.1    GAMC01008932    JAB97623.1    GAMC01008931    JAB97624.1    GECZ01003504    JAS66265.1    GECU01031343    JAS76363.1    GEBQ01031640    GEBQ01026161    JAT08337.1    JAT13816.1    AB817303    BAO01070.1    AB817304    BAO01071.1    KC439535    AGX85003.1    CH933806    EDW14515.1    CH940650    EDW67432.2    CM000070    KRT00006.1    EIM52478.1    JQ433061    AFJ42283.1    CCAG010006669    CH902623    EDV30401.2    KPU72827.1    JXJN01015848    CH964232    EDW81401.2    OUUW01000005    SPP80546.1    KRT00007.1    AAAB01008846    EAA06194.6    KQ435012    KZC13832.1    KZ288376    PBC26670.1    KQ760123    OAD61850.1    GGMR01005151    MBY17770.1    JN234381    AE014297    BT015303    M81490    AAT94531.1    AHN57552.1    GFXV01005684    MBW17489.1    AHN57551.1    ABLF02032190    ABLF02032192    DQ005188    AAY46405.1    KC439538    AGX85006.1    KQ414734    KOC62323.1    GEDC01021184    GEDC01009041    JAS16114.1    JAS28257.1    KC439537    AGX85005.1    CH477497    EAT39936.1    DS233047    EDS27732.1    KK120754    KFM78969.1    GDIP01053955    JAM49760.1    MG550209    AWT50643.1    GL732531    EFX85694.1    GDIP01244017    GDIP01169617    JAJ53785.1    GDIQ01049951    JAN44786.1    GEGO01005714    JAR89690.1    CAEY01001957    GDIQ01013001    JAN81736.1    LRGB01000770    KZS16035.1   

Proteomes

UP000037510    UP000053240    UP000092445    UP000009192    UP000008792    UP000001819    + More
UP000092444    UP000092443    UP000007801    UP000092460    UP000007798    UP000078200    UP000091820    UP000268350    UP000007062    UP000076502    UP000192221    UP000242457    UP000005203    UP000000803    UP000007819    UP000053825    UP000008820    UP000002320    UP000054359    UP000000305    UP000015104    UP000076858   

PRIDE

B3XXN2    B3XXN5    P25931   

Pfam

PF00001   7tm_1

Interpro

IPR017452   GPCR_Rhodpsn_7TM        + More
IPR000276   GPCR_Rhodpsn       
IPR000611   NPY_rcpt       
IPR001681   Neurokn_rcpt       
IPR005395   NPFF_rcpt       

ProteinModelPortal

B3XXN2   A0A0S1YD83   A0A2H1V2X5   A0A0L7L8U4   A0A0S1YDM6   B3XXN5   + More
A0A194RNG8   A0A2H1VQ84   W8BKX0   W8C5P9   A0A1B6GV51   A0A1B6HNX7   A0A1B6KQU8   U3U7M9   U3U4E6   A0A1A9ZQ06   U5N1G6   B4K9P0   B4M121   A0A0R3NME0   I5ANE3   A0A0U1SQQ4   A0A1B0GFC2   A0A1A9YGR4   B3MT11   A0A1B0BK89   B4N8F0   A0A1A9UTI4   A0A1A9VZB2   A0A3B0K4J6   A0A0R3NFZ1   Q7PS45   A0A154PPP1   A0A1W4UIN3   A0A1W4U5X8   A0A2A3E4P5   A0A310SGV6   A0A087ZXB1   A0A2S2NKP8   P25931   A0A0B4LIR4   A0A2H8TU58   A0A0B4LHT6   J9JLB3   Q2QKU5   U5N1H5   A0A0L7QUK8   A0A1B6DRF1   U5N4G7   Q16Z67   B0XGN8   A0A087UNN0   A0A0P5YRX6   A0A2U9PFU7   E9G455   A0A0N8A9E0   A0A0P6G3P1   A0A147BFV4   T1KC18   A0A0P6HZ76   A0A164Z7G7  

PDB

5WS3     E-value=4.78346e-26,     Score=292

KEGG

100174930    K14072 RYamide receptor | (RefSeq) NGR-A19, BNGR-A19; neuropeptide receptor A19

GO

GO:0016021   GO:0004983   GO:0004930   GO:0001653   GO:0005886   GO:0007166   GO:0007186   GO:0008188   GO:0004995   GO:0031683   GO:0007165   GO:0001664   GO:0005525   GO:0016491   GO:0003824  

Subcellular location

Cell membrane  

Length:

328

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

129.06733

Exp number, first 60 AAs:

0.01986

Total prob of N-in:

0.00260

outside

1  -  64

TMhelix

65  -  87

inside

88  -  98

TMhelix

99  -  121

outside

122  -  140

TMhelix

141  -  159

inside

160  -  179

TMhelix

180  -  199

outside

200  -  233

TMhelix

234  -  256

inside

257  -  281

TMhelix

282  -  304

outside

305  -  328

 

 

Pi

269.252133

Theta

183.804369

Tajima's D

0.954896

CLR

0.519105

CSRT

0.645867706614669

Interpretation

Uncertain