Gene

KWMTBOMO05163

Pre Gene Modal

BGIBMGA012491

Annotation

PREDICTED:_fatty-acid_amide_hydrolase_2-B_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr9(-):9301857-9315257      View in EpiBrowser

Full name

Cytoplasmic tRNA 2-thiolation protein 2      

Location in the cell

Mitochondrial   Reliability : 1.937

CDS

ATGAGGAGGTTTCTCAGATTTCTCGTATCGTTGCTGGCCATCATAGTGGTGCCGGTTTCATATTTTTCAAGCTTCAAACGAAAACGGAAATGTCCCCCGCCAACAAATCCCATCCTCTTCAAATCAGCAACTAAGCTAGCAGATATGATAAGAAAGAAACAGATAACATCGGAAGAGGTTGTGTCTGCGTTTATAGAACGGTGTAAAGAAGTTAATCCTTACGTAAACGCTGTAATCGAACCACGGTATGAAGTAGCGCTAAGAGAAGCAAGAGGAATAGACAAAATGATAAAGTCAACAGATCGCACGCCAGAAGAATTAGAACAGGAATATCCACTATTGGGAATTCCGCTTACTATCAAAGAAAGTATAGCGGTTGAGGGCATGAGCAATGATTGCGGAACGGTATACACAAATAGAAATCCAGCCAAGAAAGACGCGGCTATTGTCAGGCAAGCCAGAGCGGCTGGTGCAATTCCCATAGCTGTAACCAGTACACCCCAGTTGTGCATGAACTGGGAAACATACAATAATGTTATAGGAGTAACGATGAACCCTTACGATCCGAAACGTACAACTGGAGGCTCTTCGGGGGGTGAGTCGGCTTTGATTTCTTCAGCAGCATCGCTAATAGGACTCGGATCGGATATGGCTGGGTCCCTTAGATTGCCTCCAATGTTCACTGGAATCTATGGACACAAACCATCACCTAGATTACTTTCGATTGAAGGACACATACCAGACTGCTTGGATCCTGATTTTGAAGAATATTTCACTCTTGGTCCTTTAACACGCTACGCCGAAGATTTAGCACTTATGTTAAAAGTTTTAAAGAAACCTGGAAGCCCTGACATACCTTTCGATAAACCGGTTGACGTATCAACACTGAAATTCTATTACATGGAAAGTGATGGCAGTAACGTTTCCGATTCCATTGGTCGTGACGTCAAGATGGCTATGCAAAAAACGCGGGAGTACCTCAAACAAACCTATAATATCGAAGCGAAACCGCTAAGCATAAAAAACATCGAACACATGTGGGAGATAAGCGTCAGAGTATTAATGAATATAAGCCACGTTCGCAACATCTACACTGATCCGAACAATCCTAAGCAATGGGTATCGATCTGGCCTGAAATCATCAAGAAAATGTTTGGTTTATCGAACAACAACTTTTTTTCTGTTTGCTATGGTCCTTTGAAGAAATTCTTTGATGCCCTACCGAGAAGCTACTACAAGAACCTTCTAACTAAATTCGAAGACATTAAAACTGAATTTGAGACAATTTTATCTGACGATGCAGTTTTGTTGTTTCCGACTTTTCCACATCCCGCCCACTTGCACTACCGAGTGTACTATAAATTTTTGAACTGTGGATATTTAACGATGTTCAATGCATTAGGGCTGCCAGTTACGGCCTGTCCGATTGAAATGTCGAAAAAAGGCCTCCCTGTCGGCATCCAAATTGCGGCAAACAGATACAAAGATCATTTAACTGTGGCGGTCGCTAATGAATTTGAGAAAGCATTCGGTGGCTGGGCAGCTCCTAATAAAGATTCGGTTACAGTATAG

Protein

MRRFLRFLVSLLAIIVVPVSYFSSFKRKRKCPPPTNPILFKSATKLADMIRKKQITSEEVVSAFIERCKEVNPYVNAVIEPRYEVALREARGIDKMIKSTDRTPEELEQEYPLLGIPLTIKESIAVEGMSNDCGTVYTNRNPAKKDAAIVRQARAAGAIPIAVTSTPQLCMNWETYNNVIGVTMNPYDPKRTTGGSSGGESALISSAASLIGLGSDMAGSLRLPPMFTGIYGHKPSPRLLSIEGHIPDCLDPDFEEYFTLGPLTRYAEDLALMLKVLKKPGSPDIPFDKPVDVSTLKFYYMESDGSNVSDSIGRDVKMAMQKTREYLKQTYNIEAKPLSIKNIEHMWEISVRVLMNISHVRNIYTDPNNPKQWVSIWPEIIKKMFGLSNNNFFSVCYGPLKKFFDALPRSYYKNLLTKFEDIKTEFETILSDDAVLLFPTFPHPAHLHYRVYYKFLNCGYLTMFNALGLPVTACPIEMSKKGLPVGIQIAANRYKDHLTVAVANEFEKAFGGWAAPNKDSVTV

Description

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Similarity

Belongs to the CTU2/NCS2 family.

Feature

chain  Cytoplasmic tRNA 2-thiolation protein 2

Uniprot

H9JSI0   A0A2H1V6Y6   A0A2A4J8W8   A0A212F9Z9   A0A194RS76   A0A2A4J9E8   + More
S4NRR4   A0A0L0CLG6   A0A1B6IHI7   Q7KSA4   Q9I7I6   B4PPP2   A0A0R1E0X8   B3NYX5   B4IIB2   A0A1W4UY27   A0A0P8XYZ4   W8BUC2   B4JXT0   A0A1B6MC63   A0A1I8NV19   A0A0P8ZZU7   A0A0Q9X2J9   B4K7R2   B4M196   A0A0Q9WFY7   A0A0K8W879   A0A034VA70   B4NFW5   A0A0A1XD04   B3M0C2   A0A034VCY2   A0A0A1WEH7   A0A0L7QQF5   A0A0M4ERM4   A0A3B0JQC5   A0A067R9Z7   A0A1B0DF22   A0A1A9UJV6   A0A1B0G122   A0A1B6DM41   B4QS22   A0A1B6CLB9   A0A1B6KZ86   A0A1B6GHK4   A0A1B6GMQ6   A0A1B6GKN2   A0A182Y3R3   A0A0R1E6F6   A0A182PSK5   F4WG47   A0A026WID5   A0A182QF01   A0A1A9W1Q6   A0A158NT29   A0A182NRV4   A0A182RIM1   F5HMI2   A0A182JRZ3   A0A154PFX4   A0A182VZK5   A0A182WSR6   Q7PUX1   A0A2C9GKK9   A0A182IKK7   B4GN21   E2C8F4   A0A182HLL9   Q29BR1   A0A069DUG6   E2AI08   A0A182MS48   B0W356   A0A1B0B703   D6W8X9   A0A1A9YB02   A0A151XBS6   A0A182VKT0   A0A182TGM9   A0A1Q3FF94   Q177C1   A0A224XEL5   A0A1A9Z7F0   A0A1Q3FFE3   A0A195EGG7   T1HYL5   A0A023EUR9   A0A195BG92   A0A195C6L8   A0A182F7I2   A0A023EUW5   A0A2J7PRK9   Q8MZ56   W5JIS9   A0A067R7C9   A0A146KYU1   A0A146LKA9   U5EY65   A0A1W4XEY2  

Pubmed

19121390    22118469    26354079    23622113    26108605    10731132    + More
12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17994087    17550304    18057021    24495485    25348373    25830018    24845553    25244985    21719571    24508170    21347285    12364791    14747013    17210077    20798317    15632085    26334808    18362917    19820115    17510324    24945155    26483478    20920257    23761445    26823975   

EMBL

BABH01027885    BABH01027886    ODYU01001002    SOQ36610.1    NWSH01002432    PCG68309.1    + More
AGBW02009539    OWR50561.1    KQ459984    KPJ18921.1    PCG68308.1    GAIX01014342    JAA78218.1    JRES01000232    KNC33140.1    GECU01021339    JAS86367.1    AE014297    AAN14353.1    AAN14354.1    AHN57430.1    BT031317    AAG22162.3    ABY21730.1    CM000160    EDW96142.2    KRK02936.1    CH954181    EDV48378.1    CH480842    EDW49656.1    CH902617    KPU80096.1    KPU80097.1    GAMC01013832    GAMC01013831    GAMC01013830    GAMC01013829    JAB92724.1    CH916377    EDV90492.1    GEBQ01006456    JAT33521.1    KPU80099.1    KPU80100.1    CH933806    KRG02125.1    EDW16433.2    CH940650    EDW67507.1    KRF83322.1    GDHF01021979    GDHF01005100    JAI30335.1    JAI47214.1    GAKP01019538    GAKP01019537    JAC39414.1    CH964251    EDW83182.1    GBXI01005481    JAD08811.1    EDV43128.2    GAKP01019539    JAC39413.1    GBXI01017484    JAC96807.1    KQ414786    KOC60847.1    CP012526    ALC47197.1    OUUW01000007    SPP82582.1    KK852827    KDR15404.1    AJVK01058480    CCAG010008718    GEDC01010553    JAS26745.1    CM000364    EDX12218.1    GEDC01023120    JAS14178.1    GEBQ01023247    JAT16730.1    GECZ01007888    JAS61881.1    GECZ01006054    GECZ01001641    JAS63715.1    JAS68128.1    GECZ01008646    GECZ01006763    JAS61123.1    JAS63006.1    KRK02935.1    GL888128    EGI66814.1    KK107185    EZA55775.1    AXCN02000250    ADTU01025480    ADTU01025481    AAAB01008987    EGK97504.1    KQ434896    KZC10722.1    EAA00887.6    APCN01000909    CH479186    EDW39147.1    GL453666    EFN75789.1    CM000070    EAL26936.5    GBGD01001121    JAC87768.1    GL439621    EFN66916.1    AXCM01000082    DS231830    EDS30764.1    JXJN01009331    KQ971312    EEZ98236.2    KQ982320    KYQ57815.1    GFDL01008820    JAV26225.1    CH477378    EAT42271.1    GFTR01006982    JAW09444.1    GFDL01008823    JAV26222.1    KQ978957    KYN26997.1    ACPB03016841    GAPW01000882    JAC12716.1    KQ976488    KYM83612.1    KQ978205    KYM96482.1    JXUM01115846    JXUM01115847    GAPW01000817    KQ565921    JAC12781.1    KXJ70534.1    NEVH01021956    PNF18975.1    AY113345    AAM29350.1    ADMH02001371    ETN62795.1    KDR15405.1    GDHC01017078    JAQ01551.1    GDHC01010221    JAQ08408.1    GANO01002174    JAB57697.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000037069    UP000000803    + More
UP000002282    UP000008711    UP000001292    UP000192221    UP000007801    UP000001070    UP000095300    UP000009192    UP000008792    UP000007798    UP000053825    UP000092553    UP000268350    UP000027135    UP000092462    UP000078200    UP000092444    UP000000304    UP000076408    UP000075885    UP000007755    UP000053097    UP000075886    UP000091820    UP000005205    UP000075884    UP000075900    UP000007062    UP000075881    UP000076502    UP000075920    UP000076407    UP000075840    UP000075880    UP000008744    UP000008237    UP000001819    UP000000311    UP000075883    UP000002320    UP000092460    UP000007266    UP000092443    UP000075809    UP000075903    UP000075902    UP000008820    UP000092445    UP000078492    UP000015103    UP000078540    UP000078542    UP000069272    UP000069940    UP000249989    UP000235965    UP000000673    UP000192223   

PRIDE

H9JSI0    Q7KSA4    Q9I7I6    Q8MZ56   

Pfam

PF01425   Amidase        + More
PF10288   CTU2
PF08711   Med26

Interpro

IPR023631   Amidase_dom        + More
IPR036928   AS_sf       
IPR020556   Amidase_CS       
IPR019407   CTU2       
IPR014729   Rossmann-like_a/b/a_fold       
IPR017923   TFIIS_N       
IPR035441   TFIIS/LEDGF_dom_sf       

SUPFAM

SSF75304   SSF75304       

Gene 3D

3.90.1300.10     3.40.50.620     1.20.930.10    

ProteinModelPortal

H9JSI0   A0A2H1V6Y6   A0A2A4J8W8   A0A212F9Z9   A0A194RS76   A0A2A4J9E8   + More
S4NRR4   A0A0L0CLG6   A0A1B6IHI7   Q7KSA4   Q9I7I6   B4PPP2   A0A0R1E0X8   B3NYX5   B4IIB2   A0A1W4UY27   A0A0P8XYZ4   W8BUC2   B4JXT0   A0A1B6MC63   A0A1I8NV19   A0A0P8ZZU7   A0A0Q9X2J9   B4K7R2   B4M196   A0A0Q9WFY7   A0A0K8W879   A0A034VA70   B4NFW5   A0A0A1XD04   B3M0C2   A0A034VCY2   A0A0A1WEH7   A0A0L7QQF5   A0A0M4ERM4   A0A3B0JQC5   A0A067R9Z7   A0A1B0DF22   A0A1A9UJV6   A0A1B0G122   A0A1B6DM41   B4QS22   A0A1B6CLB9   A0A1B6KZ86   A0A1B6GHK4   A0A1B6GMQ6   A0A1B6GKN2   A0A182Y3R3   A0A0R1E6F6   A0A182PSK5   F4WG47   A0A026WID5   A0A182QF01   A0A1A9W1Q6   A0A158NT29   A0A182NRV4   A0A182RIM1   F5HMI2   A0A182JRZ3   A0A154PFX4   A0A182VZK5   A0A182WSR6   Q7PUX1   A0A2C9GKK9   A0A182IKK7   B4GN21   E2C8F4   A0A182HLL9   Q29BR1   A0A069DUG6   E2AI08   A0A182MS48   B0W356   A0A1B0B703   D6W8X9   A0A1A9YB02   A0A151XBS6   A0A182VKT0   A0A182TGM9   A0A1Q3FF94   Q177C1   A0A224XEL5   A0A1A9Z7F0   A0A1Q3FFE3   A0A195EGG7   T1HYL5   A0A023EUR9   A0A195BG92   A0A195C6L8   A0A182F7I2   A0A023EUW5   A0A2J7PRK9   Q8MZ56   W5JIS9   A0A067R7C9   A0A146KYU1   A0A146LKA9   U5EY65   A0A1W4XEY2  

PDB

5H6T     E-value=1.65899e-16,     Score=212

KEGG

101741517    K19176 fatty acid amide hydrolase 2 [EC:3.5.1.99] | (RefSeq) fatty-acid amide hydrolase 2

GO

GO:0016021   GO:0016787   GO:0016874   GO:0000049   GO:0034227   GO:0005737   GO:0002098   GO:0032447   GO:0016779   GO:0005634  

Subcellular location

Cytoplasm  
Nucleus  

SignalP

Position:   1 - 24,         Likelihood:  0.621914

 

 

Length:

523

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

18.66739

Exp number, first 60 AAs:

18.27974

Total prob of N-in:

0.97214

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  25

outside

26  -  523

 

 

Pi

185.828523

Theta

154.838543

Tajima's D

0.755415

CLR

0.628196

CSRT

0.584120793960302

Interpretation

Uncertain