Gene

KWMTBOMO05162  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012492

Annotation

G_protein_alpha_q_isoform_1_[Bombyx_mori]

Location

Bomo_Chr9(-):9280239-9296477      View in EpiBrowser

Full name

G protein alpha q subunit       + More
Guanine nucleotide-binding protein G(q) subunit alpha      

Alternative Name

Guanine nucleotide-binding protein G(q) subunit alpha
Guanine nucleotide-binding protein alpha-q
dGQalpha

Location in the cell

Cytoplasmic   Reliability : 1.607 Nuclear   Reliability : 1.729 PlasmaMembrane   Reliability : 1.043

CDS

ATGGAGTGCTGCATGTCAGAAGAAGCAAAGGAACAAAAAAGGATCAATCAAGAAATAGAGAGGCAACTCAGAAAGGACAAACGAGATGCCAGAAGAGAACTCAAACTGCTCCTACTTGGAACTGGAGAGTCGGGCAAATCTACTTTCATCAAGCAGATGAGAATCATCCACGGCTCGGGTTATAGCGACGAAGACAAGCGCGGCTTCATCAAACTCGTTTACCAGAACATCTTCATGGCGATGCAGAGTATGATACGCGCCATGGACCTACTAACAATACAATATGGGAACCCGTCCAATGTAGAAAAGGCGGAATTGATATCATCGATCGACTTTGAGAGTGTGACAACGTTCGAGAGTCCGTACGTGGAAGCTATCAAGGGCTTATGGGCCGATTCCGGCATCCAGGAATGTTATGATCGCAGGCGAGAATACCAACTTACTGACTCGGCCAAATACTACTTGCAGGAGATCGACCGCGTCGCAGCGCCAAATTACCTACCAACCGAACAGGATATCCTCCGTGTGAGAGTTCCCACAACGGGCATCATAGAGTACCCATTTGACTTGGAGGAAATACGATTTCGAATGGTGGACGTCGGGGGCCAGAGATCCGAAAGAAGGAAGTGGATCCATTGTTTCGAAAACGTCACATCCATCATATTCTTAGTAGCTCTTAGTGAATATGACCAAATTTTATTCGAATCAGAGAACGAGAATCGAATGGAAGAATCGAAAGCATTGTTCAAGACCATCATAACGTACCCGTGGTTCCAGCACTCCTCGGTCATTCTGTTTCTCAACAAAAAGGATTTGCTCGAGGAGAAGATTATGTATTCTCACCTTGTTGACTACTTCCCTGAATACGACGGCCCGCAACGCGACGCCAATGCGGCGCGCGAGTTCATTCTGCGGATGTTCGTCGACTTGAACCCGGACGCGGAGAAAATCATCTATTCGCATTTCACATGTGCGACAGATACCGAAAACATCCGGTTCGTATTCGCCGCCGTAAAGGACACAATCCTACAGTCCAACCTGAAAGAGTACAATCTCGTTTAA

Protein

MECCMSEEAKEQKRINQEIERQLRKDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFIKLVYQNIFMAMQSMIRAMDLLTIQYGNPSNVEKAELISSIDFESVTTFESPYVEAIKGLWADSGIQECYDRRREYQLTDSAKYYLQEIDRVAAPNYLPTEQDILRVRVPTTGIIEYPFDLEEIRFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESENENRMEESKALFKTIITYPWFQHSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDANAAREFILRMFVDLNPDAEKIIYSHFTCATDTENIRFVFAAVKDTILQSNLKEYNLV

Description

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Could be the transducin analog, an amplifier and one of the transducers of a visual impulse that performs the coupling between opsin and cGMP-phosphodiesterase. Could mediate a subset of olfactory and gustatory responses.

Subunit

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

Similarity

Belongs to the G-alpha family. G(q) subfamily.

Keywords

Alternative splicing   Complete proteome   GTP-binding   Lipoprotein   Magnesium   Metal-binding   Nucleotide-binding   Palmitate   Reference proteome   Sensory transduction   Transducer   Vision  

Feature

chain  G protein alpha q subunit
splice variant  In isoform A.

Uniprot

Q76FN3   A7UGE0   Q58FC0   Q8T6P8   A0A1B6MFS6   A0A0N7Z9B8   + More
A0A2J7PPC1   A0A084WJG2   A0A224XEZ3   A0A069DT72   Q7PHK1   A0A023ERK8   T1DIA5   Q16SS3   A0A1B6J1F2   G0ZGG9   B0WUH2   A0A1Q3FPS9   A0A2M4CSY8   A0A2M3Z6J2   A0A2M4ACP5   A0A2M4BSD5   A0A1L8DMB0   A0A1B6EDC0   I3RY40   A6YPC7   A0A2H8TX60   J9JVC1   A0A2S2PFK8   A0A0K8TRB9   A7UT58   V9IA31   A0A0C9R5C0   A0A1W4X717   A0A0C5UFC4   A0A151I7I0   A0A2J7PP86   A0A1Y1KS43   A0A1S4GN31   A0A1Q3FVH1   A0A1I8P9V9   W8B807   A7UT47   V5GQZ8   A0A1I8M2K0   A0A164WFI7   E9GJ31   A0A0A1X7I1   A0A0K2UV44   D3TMJ4   A0A1W4VQI7   A0A3B0JLU7   N6VFD7   V9IAK1   A0A0P9BZI8   P23625-2   A0A0R1DQG4   A0A0J9RB68   A0A0Q5VNA4   B4KRT9   A0A132AH75   A0A2H4WAL9   A0A1W4WWE8   B4LLR2   C7G308   A0A1D2N2Y5   B4J703   A0A3S2NII8   A0A2P1JJ34   A0A1Z5L5T5   A7UT60   Q9U473   P91950   A0A2R5LE43   A0A293N0N7   A7UT57   A0A1I8M2J7   V5HU55   A0A087UP57   Q6ITD0   D6W977   A0A1I8PA13   A0A1Y1KRW1   A0A0R3NP81   A0A1B6IGC8   A0A034W207   A0A0P8XQ54   A0A023FVY2   A0A0Q5VXE0   N6UN36   N6TLI3   A0A3B0J0J8   A0A0J9TZX9   A0A0R1DW63   A0A0Q9WW81   A0A1E1XS90   B5BRC6   A0A1W4VCT4   A0A0C5U2U3   A0A0F7VHI3  

Pubmed

15545611    15776452    11985591    27129103    24438588    26334808    + More
12364791    14747013    17029251    17210077    24945155    24330624    17510324    26369729    26823975    28004739    24495485    25315136    21292972    25830018    20353571    15632085    17994087    18057021    2125225    8524786    10731132    12537572    12537569    17550304    22936249    26555130    29182505    27289101    28528879    10781594    9166716    25765539    18362917    19820115    25348373    23537049    29209593   

EMBL

AB105070    AB167959    AB425234    BAC85104.1    BAD74002.1    BAG69142.1    + More
EU057176    ABU45982.1    AY957405    AAX56092.1    AF448447    AAL93221.1    GEBQ01005170    JAT34807.1    GDKW01000987    JAI55608.1    NEVH01023278    PNF18156.1    ATLV01024026    KE525348    KFB50356.1    GFTR01005379    JAW11047.1    GBGD01001963    JAC86926.1    DQ182015    AAAB01008900    ABA56307.1    EAA44510.1    EDO64073.1    GAPW01002284    JAC11314.1    GALA01001041    JAA93811.1    CH477667    EAT37512.1    GECU01014714    JAS92992.1    JF273640    AEK80437.1    DS232105    EDS34954.1    GFDL01005436    JAV29609.1    GGFL01004288    MBW68466.1    GGFM01003363    MBW24114.1    GGFK01005245    MBW38566.1    GGFJ01006854    MBW55995.1    GFDF01006492    JAV07592.1    GEDC01001360    JAS35938.1    JQ922538    AFK32778.1    EF638906    ABR37295.1    GFXV01006576    MBW18381.1    ABLF02026380    GGMR01015583    MBY28202.1    GDAI01000686    JAI16917.1    EDO64069.1    JR036960    AEY57502.1    GBYB01003140    JAG72907.1    KM610200    GDHC01003334    AJQ81031.1    JAQ15295.1    KQ978415    KYM94073.1    PNF18157.1    GEZM01075336    JAV64134.1    EDO64072.1    GFDL01003603    JAV31442.1    GAMC01009205    GAMC01009202    GAMC01009201    JAB97350.1    EDO64067.1    EDO64074.1    GALX01001897    JAB66569.1    LRGB01001253    KZS13216.1    GL732547    EFX80557.1    GBXI01016231    GBXI01007592    JAC98060.1    JAD06700.1    HACA01024420    HACA01024421    CDW41782.1    CCAG010010866    CCAG010010867    EZ422646    ADD18922.1    OUUW01000001    SPP74216.1    CM000071    ENO01765.1    JR036959    AEY57501.1    CH902619    KPU76734.1    KPU76735.1    M58016    U31092    AE013599    AY118511    BT024269    CM000158    KRJ99420.1    CM002911    KMY93271.1    KMY93272.1    KMY93273.1    KMY93278.1    KMY93279.1    CH954179    KQS62813.1    KQS62816.1    KQS62817.1    KQS62819.1    CH933808    EDW09380.1    KRG04642.1    JXLN01014975    KPM10344.1    MG020529    AUC64085.1    CH940648    EDW61935.1    KRF80351.1    AB488394    BAH98115.1    LJIJ01000266    ODM99643.1    CH916367    EDW00991.1    RSAL01000027    RVE51913.1    MF279133    AVN99026.1    GFJQ02004193    JAW02777.1    EDO64071.1    EDO64075.1    AF201328    AAF19378.1    U89139    GGLE01003592    MBY07718.1    GFWV01020237    MAA44965.1    EDO64076.1    GANP01002514    JAB81954.1    KK120833    KFM79146.1    AY626792    QCYY01002453    AAT44837.1    ROT70208.1    KQ971312    EEZ98203.2    GEZM01075337    JAV64133.1    KRT02740.1    GECU01021724    JAS85982.1    GAKP01011157    GAKP01011154    JAC47798.1    KPU76730.1    GBBL01001354    JAC25966.1    KQS62811.1    APGK01016400    APGK01016401    APGK01016402    APGK01016403    KB739838    ENN82106.1    APGK01031716    KB740820    KB632375    ENN78848.1    ERL93848.1    SPP74215.1    KMY93270.1    KRJ99425.1    CH964282    KRG00252.1    GFAA01001264    JAU02171.1    AB425233    BAG69141.1    KM610199    AJQ81030.1    LN830665    CFW94174.1   

Proteomes

UP000235965    UP000030765    UP000007062    UP000008820    UP000002320    UP000007819    + More
UP000192223    UP000078542    UP000095300    UP000095301    UP000076858    UP000000305    UP000092444    UP000192221    UP000268350    UP000001819    UP000007801    UP000000803    UP000002282    UP000008711    UP000009192    UP000008792    UP000094527    UP000001070    UP000283053    UP000054359    UP000283509    UP000007266    UP000019118    UP000030742    UP000007798   

PRIDE

Q76FN3    P23625    V5HU55    B5BRC6   

Pfam

PF00503   G-alpha

Interpro

IPR000654   Gprotein_alpha_Q        + More
IPR001019   Gprotein_alpha_su       
IPR027417   P-loop_NTPase       
IPR011025   GproteinA_insert       

SUPFAM

SSF47895   SSF47895        + More
SSF52540   SSF52540       

Gene 3D

1.10.400.10    

CDD

cd00066  G-alpha

ProteinModelPortal

Q76FN3   A7UGE0   Q58FC0   Q8T6P8   A0A1B6MFS6   A0A0N7Z9B8   + More
A0A2J7PPC1   A0A084WJG2   A0A224XEZ3   A0A069DT72   Q7PHK1   A0A023ERK8   T1DIA5   Q16SS3   A0A1B6J1F2   G0ZGG9   B0WUH2   A0A1Q3FPS9   A0A2M4CSY8   A0A2M3Z6J2   A0A2M4ACP5   A0A2M4BSD5   A0A1L8DMB0   A0A1B6EDC0   I3RY40   A6YPC7   A0A2H8TX60   J9JVC1   A0A2S2PFK8   A0A0K8TRB9   A7UT58   V9IA31   A0A0C9R5C0   A0A1W4X717   A0A0C5UFC4   A0A151I7I0   A0A2J7PP86   A0A1Y1KS43   A0A1S4GN31   A0A1Q3FVH1   A0A1I8P9V9   W8B807   A7UT47   V5GQZ8   A0A1I8M2K0   A0A164WFI7   E9GJ31   A0A0A1X7I1   A0A0K2UV44   D3TMJ4   A0A1W4VQI7   A0A3B0JLU7   N6VFD7   V9IAK1   A0A0P9BZI8   P23625-2   A0A0R1DQG4   A0A0J9RB68   A0A0Q5VNA4   B4KRT9   A0A132AH75   A0A2H4WAL9   A0A1W4WWE8   B4LLR2   C7G308   A0A1D2N2Y5   B4J703   A0A3S2NII8   A0A2P1JJ34   A0A1Z5L5T5   A7UT60   Q9U473   P91950   A0A2R5LE43   A0A293N0N7   A7UT57   A0A1I8M2J7   V5HU55   A0A087UP57   Q6ITD0   D6W977   A0A1I8PA13   A0A1Y1KRW1   A0A0R3NP81   A0A1B6IGC8   A0A034W207   A0A0P8XQ54   A0A023FVY2   A0A0Q5VXE0   N6UN36   N6TLI3   A0A3B0J0J8   A0A0J9TZX9   A0A0R1DW63   A0A0Q9WW81   A0A1E1XS90   B5BRC6   A0A1W4VCT4   A0A0C5U2U3   A0A0F7VHI3  

PDB

4QJ5     E-value=2.09268e-171,     Score=1546

KEGG

692442    K04634 guanine nucleotide-binding protein G(q) subunit alpha | (RefSeq) Gq; G protein alpha q

PATHWAY

04745    Phototransduction - fly - Bombyx mori (domestic silkworm)

GO

GO:0001664   GO:0007186   GO:0005525   GO:0031683   GO:0003924   GO:0007188   GO:0005834   GO:0005886   GO:0016056   GO:0016028   GO:0007608   GO:0002385   GO:0007629   GO:0007601   GO:0007602   GO:0046872   GO:0046673   GO:1900073   GO:0006897   GO:0030322   GO:0071244   GO:0016199   GO:0043052   GO:0016027   GO:0007202   GO:0016060   GO:0070050   GO:0007165   GO:0016874   GO:0004871   GO:0019001   GO:0016491   GO:0003824  

PANTHER

PTHR10218  

Length:

353

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.14896

Exp number, first 60 AAs:

0.00303

Total prob of N-in:

0.03302

outside

1  -  353

 

 

Pi

274.012516

Theta

186.092239

Tajima's D

1.167679

CLR

0.219284

CSRT

0.701664916754162

Interpretation

Uncertain