SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO05055  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA012560
Annotation
glycerol-3-phosphate_dehydrogenase-1_[Bombyx_mori]
Full name
Glycerol-3-phosphate dehydrogenase [NAD(+)]       + More
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic      
Location in the cell
Cytoplasmic   Reliability : 3.084
 

Sequence

CDS
ATGGCAGATAAACAGCCAAAGAACAAAGTTTGCATCGTTGGATCGGGAAACTGGGGTTCTGCTATTGCGAAAATTGTTGGTCGAAATGCTGCGAGTCTATCAAATTTTGAGGATAGAGTTACAATGTGGGTGTATGAAGAAATAATTGAAGGAAAGAAGTTAACTGAAATAATCAATGAAACTCATGAAAATGTTAAATACCTGCCTGGCCACAAATTGCCTTCTAATGTTGTTGCTGTTCCAGATGTAGTTGAAGCTGCAAAAGATGCTGATCTTTTAATATTTGTGGTGCCTCATCAATTTGTCAGAACTATCTGCTCTACTTTGCTTGGAAAAATAAAGCCAACTGCAGCTGCTCTGTCTTTGATTAAGGGATTTGATATAGCCGAAGGTGGTGGCATCGATCTTATATCACATATTATTACAAGATGCCTAAAAATTCCCTGTGCTGTATTAATGGGAGCCAATATTGCATCGGAGGTTGCTGAGGAAAAATTCTGCGAAACGACCATTGGTTGTCGGGACGTAATGCTGGCTCCGTTAATGCGGGATATCATACAGACAGACTACTTCAGGGTCGTGGTGGTGGACGATGAGGACGCAGTCGAAATATGTGGAGCGTTAAAGAACATTGTGGCAGTGGGTGCGGGTTTCGTGGATGGCCTCGGCTACGGTGATAACACAAAGGCTGCTGTCATCAGACTCGGTCTCATGGAGATGATCAAATTCGTTGATGTGTTCTACCCGGGAAGTAAGCTGAGCACGTTCTTCGAGTCATGCGGTGTCGCAGATTTAATAACGACCTGCTACGGGGGCAGAAACAGACGAGTTGCCGAAGCGTTTGTTAAAACGGGACGGTCAATAAAAGAGCTGGAAGACGAAATGCTTAACGGTCAGAAACTACAAGGTCCTATCACCGCGGAGGAAGTAAACCATATGCTCGCTAATAAAAATATGGAAAACAAGTTCCCTTTGTTCACTGCGGTGTTCCGCATCTGTCGCGGAGAACTCAAACCGAACGACTTTATTGATTGCATTCGCAGTCACCCGGAACACATGAAACTGCCCTTGGTCAAATGTTCACTGTGA
Protein
MADKQPKNKVCIVGSGNWGSAIAKIVGRNAASLSNFEDRVTMWVYEEIIEGKKLTEIINETHENVKYLPGHKLPSNVVAVPDVVEAAKDADLLIFVVPHQFVRTICSTLLGKIKPTAAALSLIKGFDIAEGGGIDLISHIITRCLKIPCAVLMGANIASEVAEEKFCETTIGCRDVMLAPLMRDIIQTDYFRVVVVDDEDAVEICGALKNIVAVGAGFVDGLGYGDNTKAAVIRLGLMEMIKFVDVFYPGSKLSTFFESCGVADLITTCYGGRNRRVAEAFVKTGRSIKELEDEMLNGQKLQGPITAEEVNHMLANKNMENKFPLFTAVFRICRGELKPNDFIDCIRSHPEHMKLPLVKCSL

Summary

Catalytic Activity
NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH
Subunit
Homodimer.
Similarity
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Belongs to the MT-A70-like family.
Keywords
Alternative splicing   Complete proteome   Cytoplasm   Direct protein sequencing   NAD   Oxidoreductase   Polymorphism   Reference proteome  
Feature
chain  Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
splice variant  In isoform GPDH-3.
EC Number
1.1.1.8
EMBL
AB164060    BAD38674.1    AB164061    BAD38675.1    BABH01032141    KY565577    + More
ATU31389.1    KQ459606    KPI91302.1    KQ461133    KPJ08866.1    AGBW02007748    OWR54615.1    NWSH01002106    PCG69167.1    PCG69168.1    KF170736    AGW15345.1    ODYU01005592    SOQ46581.1    GDAI01001486    JAI16117.1    KQ971312    KYB29132.1    KYB29133.1    EEZ98249.2    GALX01004003    JAB64463.1    GAMD01002723    JAA98867.1    GGFL01004735    MBW68913.1    GGFM01002002    MBW22753.1    GGFK01002416    MBW35737.1    GGFK01002415    MBW35736.1    ADMH02000065    ETN67939.1    AXCN02000594    CH477221    EAT47333.1    GGFM01001967    MBW22718.1    APGK01048501    KB741112    ENN73826.1    GFDF01001832    JAV12252.1    EAT47334.1    ATLV01017808    KE525192    KFB42472.1    GEZM01044288    JAV78327.1    CVRI01000073    CRL07613.1    AJWK01008357    AJWK01008358    BT128609    AEE63566.1    KQ435762    KOX75460.1    EAT47332.1    JXUM01011468    JXUM01011469    JXUM01011470    JXUM01011471    KQ560331    KXJ83002.1    GANO01001833    JAB58038.1    GL445725    EFN89159.1    GAPW01002322    JAC11276.1    KB632184    ERL89623.1    NNAY01000716    OXU26833.1    AAAB01008807    EDO64530.1    APCN01000215    EAA03917.3    GFDL01006826    JAV28219.1    DS231815    EDS35205.1    ADTU01003700    AXCM01000512    JRES01000501    KNC30725.1    LJIG01002821    KRT84119.1    AY438978    AAR13229.1    GL441497    EFN64733.1    GAMC01019481    JAB87074.1    CH963857    EDW76352.1    GFDG01000838    JAV17961.1    GFDG01003888    JAV14911.1    KK107019    QOIP01000007    EZA62634.1    RLU20422.1    GAMC01019478    JAB87077.1    GALA01001060    JAA93792.1    KA649718    AFP64347.1    GEDC01022718    JAS14580.1    KA649578    KA649719    AFP64348.1    J04567    X14179    X67650    X61223    X61224    AE014134    AY058492    X80204    M13786    J03927    CM002910    KMY88404.1    AGB92649.1    CM000157    KRJ98068.1    KA646634    AFP61263.1    AGB92647.1    EDW88874.1    CH902620    KPU73708.1    CM000361    EDX03874.1    KMY88403.1    BT044153    ACH92218.1    AGB92648.1    EDV31931.1    OUUW01000010    SPP86067.1    CH954177    KQS70198.1    CH916368    EDW03020.1    EDV57920.1    U59682    CH379058    AY754559    L41249    U47885    AB019506    AB019507    D50091    BAA20577.1   
Pfam
PF01210   NAD_Gly3P_dh_N        + More
PF07479   NAD_Gly3P_dh_C
PF12473   DUF3694
PF00498   FHA
PF01302   CAP_GLY
PF12423   KIF1B
PF00225   Kinesin
PF16183   Kinesin_assoc
PF09631   Sen15
PF13181   TPR_8
PF12569   NARP1
PF05063   MT-A70
Interpro
IPR036291   NAD(P)-bd_dom_sf        + More
IPR006168   G3P_DH_NAD-dep       
IPR008927   6-PGluconate_DH-like_C_sf       
IPR011128   G3P_DH_NAD-dep_N       
IPR013328   6PGD_dom2       
IPR017751   G3P_DH_NAD-dep_euk       
IPR006109   G3P_DH_NAD-dep_C       
IPR018593   tRNA-endonuc_su_Sen15       
IPR022164   Kinesin-like       
IPR000253   FHA_dom       
IPR036859   CAP-Gly_dom_sf       
IPR036167   tRNA_intron_Endo_cat-like_sf       
IPR008984   SMAD_FHA_dom_sf       
IPR011856   tRNA_endonuc-like_dom_sf       
IPR032923   KIF13A       
IPR022140   Kinesin-like_KIF1-typ       
IPR027640   Kinesin-like_fam       
IPR001752   Kinesin_motor_dom       
IPR032405   Kinesin_assoc       
IPR036961   Kinesin_motor_dom_sf       
IPR000938   CAP-Gly_domain       
IPR027417   P-loop_NTPase       
IPR019821   Kinesin_motor_CS       
IPR013026   TPR-contain_dom       
IPR019734   TPR_repeat       
IPR011990   TPR-like_helical_dom_sf       
IPR021183   NatA_aux_su       
IPR007757   MT-A70-like       
IPR029063   SAM-dependent_MTases       
IPR002052   DNA_methylase_N6_adenine_CS       
SUPFAM
SSF48179   SSF48179        + More
SSF51735   SSF51735       
SSF53032   SSF53032       
SSF52540   SSF52540       
SSF49879   SSF49879       
SSF74924   SSF74924       
SSF48452   SSF48452       
SSF53335   SSF53335       
PDB
1X0X     E-value=4.49075e-128,     Score=1172

Ontologies

Topology

Subcellular location
Cytoplasm  
Length:
362
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.10277
Exp number, first 60 AAs:
0.04483
Total prob of N-in:
0.06272
outside
1  -  362
 
 

Population Genetic Test Statistics

Pi
232.803312
Theta
193.773542
Tajima's D
0.587675
CLR
0.070148
CSRT
0.540522973851307
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
31250652 QNRSLLTVEQMYEDVSQDHAK 95.45 1e-08
28556443 LQGPITAEEVNHMLANK 100.00 8e-08
28556443 LQGPITAEEVNHMLANK 100.00 8e-08
28556443 GFDIAEGGGIDLISHIITR 100.00 6e-07
28556443 GELKPNDFIDCIR 100.00 6e-07
28556443 GELKPNDFIDCIR 100.00 6e-07
28556443 IKPTAAAL 100.00 6e-06
28556443 GFDIAEGGGIDLISHIITR 100.00 6e-06
28556443 LQGPITAEEVNHMLANK 100.00 1e-05
28556443 LQGPITAEEVNHMLANK 100.00 1e-05
28556443 LPSNVVAVPDVVEAAK 100.00 1e-05
28556443 LPSNVVAVPDVVEAAK 100.00 1e-05
28556443 DADLLIFVVPHQFVR 100.00 9e-05
28556443 IKPTAAAL 100.00 9e-05
28556443 YAVAPAYSAPYVTAAR 100.00 9e-05
26822097 TICSTIIGK 100.00 2e-04
26280517 VCIQQNHQIKDQHIDVKK 100.00 2e-04
24402669 VCIIGCGVPTGYGAAINTAK 100.00 2e-04
28467696 VCIQQNHQIKDQHIDVK 100.00 2e-04
28556443 VAEAFVK 100.00 2e-04
28556443 NIVAVGAGFVDGLGYGDNTK 100.00 2e-04
28556443 LPSNVVAVPDVVEAAK 100.00 0.001
28556443 LPSNVVAVPDVVEAAK 100.00 0.001
28556443 LGLMEMIK 100.00 0.001
28556443 LGLMEMIK 100.00 0.001
25044914 VTIVGSPEAQWK 100.00 0.002
28556443 GELKPNDFIDCIR 100.00 0.003
28556443 FVDVFYPGSK 100.00 0.003
28556443 FVDVFYPGSK 100.00 0.003
28556443 NAASLSNFEDR 100.00 0.013
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