Gene

KWMTBOMO05012  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008117

Annotation

PREDICTED:_vacuolar_protein_sorting-associated_protein_13C_[Bombyx_mori]

Location

Bomo_Chr9(+):5469461-5473793      View in EpiBrowser

Full name

Vacuolar protein sorting-associated protein 13      

Location in the cell

Nuclear   Reliability : 2.172

CDS

ATGCAGTATGCGGTTCATCATCACACGTTCATCGATTTAGATATCGACATTGCCTCCTCTTATATTATTGTACCGCAGACGGGAAAATACCAAGGAAAAGAGTCGTGTGTTGTCGTGAAACTTGGTGCTATAAACGTCAAGTCCGAACCTCGCTCCCAAGCCCTCGACGTACACAAATTGTATAAAGAAGGATTGGCCGACGAAGATATTCTGCGTGAGATAACCCAGCACAGCTACGATAAGATGGCACTGAAACTAACCGAAATGCAGATCGTTATAGCAACGTCGTCGGAAGATTGGCAGTCGGCTATAGCTTCGAACGAAGCGACGTCCCTGCACTTGCTGCAGCCAACGAACTTGGTCATACAAATACACAAATGTCTGATCACGGACGATCCGAGAATGCCGAAGGTCAAAGTCCGGGGTGAACTCGAGAAAATCGCTATAAGCGCCTCCGAAGACCGATTGCTGACACTTTGTGAAATATTAGTCAGTATGCCGTTACCTAATTCAGAAGAATCGGCTCAGTTGAAGCCAAGCGACTCGAAAGGATCAAGTTTGTCCTTACTGAAGTATTTAGATCCGGCTGAAAAACAAAAGAGAGACACTGCTCGCTCAAAGGAGCGGAAGAGTGACGAGCAAACTATACAGTTAACTGAAGTTGAAGCCTTCTTTATAATGAAAGGTAACGTAACGTGA

Protein

MQYAVHHHTFIDLDIDIASSYIIVPQTGKYQGKESCVVVKLGAINVKSEPRSQALDVHKLYKEGLADEDILREITQHSYDKMALKLTEMQIVIATSSEDWQSAIASNEATSLHLLQPTNLVIQIHKCLITDDPRMPKVKVRGELEKIAISASEDRLLTLCEILVSMPLPNSEESAQLKPSDSKGSSLSLLKYLDPAEKQKRDTARSKERKSDEQTIQLTEVEAFFIMKGNVT

Description

Plays a role in the survival of neurons by maintaining protein homeostasis in the central nervous system. May function as part of a lysosomal degradation pathway.

Similarity

Belongs to the VPS13 family.

Keywords

Complete proteome   Endosome   Membrane   Protein transport   Reference proteome   Transport  

Feature

chain  Vacuolar protein sorting-associated protein 13

Uniprot

H9JF20   A0A3S2LSU5   A0A2A4JAS4   A0A0N0PAP2   A0A194QM57   A0A1E1VZK4   + More
A0A1E1WNG3   A0A212EH99   A0A067RTP5   A0A182MPK1   A0A182SUD4   A0A182WB65   A0A182RA29   A0A182NLZ6   A0A182PLD4   A0A182IQ42   A0A182QNC8   A0A182LB90   Q5TSU0   A0A182HPA7   A0A182VBQ3   A0A182TV09   A0A182X4A3   A0A182JW81   A0A084WJG5   A0A1Q3FGM4   A0A1Q3FGD3   A0A182G3T1   B0WUG9   A0A182YFP8   A0A336L615   Q16SR9   A0A2P8Y000   A0A1S4E8Q6   A0A2H1W0S9   A0A2M3ZZF8   W4VRJ2   D6WCW1   W5J689   A0A2M4DRU1   A0A0P6JRN7   A0A1J1ITZ1   A0A2M4CVW7   A0A182FL84   V5GY02   N6U474   U4ULV9   A0A1Y1M0H6   A0A1L8DVL7   A0A232F955   J9K7I7   K7IXV4   A0A2H8TPG9   A0A2H8TP76   A0A1B6CUA0   E9J4Z2   T1J4H6   A0A0J7KFM8   E1ZV01   A0A3L8DLF8   A0A026WHS8   V9IL78   A0A0P4WPI9   A0A0P4W8G3   A0A154PLH2   A0A0P4WAQ3   A0A0P4W473   A0A151JQF4   E2B476   A0A1B0DB55   A0A151JY96   A0A195CYF9   A0A151X236   A0A3R7PJS0   A0A2A3EL42   A0A087ZQS4   A0A310S5Y6   B4NS47   A0A0N0BCF1   B3MHR1   A0A0P8XPG8   A0A0V0GCP3   A0A0L7RCF4   A0A1I8PU10   A0A1B6LDL1   B4MIP9   A0A1B6KWT9   A0A224XG50   A0A1I8NHV4   T1P7V0   A0A0T6BDC0   A0A0J9R7H7   B4P1S0   A0A023EZM1   A1Z713   E0VJH2  

Pubmed

19121390    26354079    22118469    24845553    20966253    12364791    + More
24438588    26483478    25244985    17510324    29403074    18362917    19820115    20920257    23761445    26999592    23537049    28004739    28648823    20075255    21282665    20798317    30249741    24508170    17994087    18057021    25315136    22936249    17550304    25474469    10731132    12537572    28107480    20566863   

EMBL

BABH01033962    BABH01033963    BABH01033964    BABH01033965    BABH01033966    BABH01033967    + More
RSAL01000238    RVE43697.1    NWSH01002177    PCG68959.1    KQ458665    KPJ05606.1    KQ461198    KPJ06050.1    GDQN01010879    JAT80175.1    GDQN01002587    JAT88467.1    AGBW02014919    OWR40856.1    KK852470    KDR23219.1    AXCM01006669    AXCN02000957    AAAB01008900    EAL40459.3    APCN01002939    ATLV01024026    ATLV01024027    KE525348    KFB50359.1    GFDL01008393    JAV26652.1    GFDL01008441    JAV26604.1    JXUM01007029    JXUM01007030    KQ560229    KXJ83724.1    DS232105    EDS34951.1    UFQS01001985    UFQT01001985    SSX12864.1    SSX32306.1    CH477667    EAT37516.1    PYGN01001102    PSN37570.1    ODYU01005601    SOQ46613.1    GGFK01000558    MBW33879.1    GANO01002385    JAB57486.1    KQ971311    EEZ98831.2    ADMH02002077    ETN59516.1    GGFL01016096    MBW80274.1    GDUN01001099    JAN94820.1    CVRI01000059    CRL03731.1    GGFL01005306    MBW69484.1    GALX01003208    JAB65258.1    APGK01040378    KB740979    ENN76405.1    KB632379    ERL94107.1    GEZM01043725    JAV78881.1    GFDF01003625    JAV10459.1    NNAY01000686    OXU26973.1    ABLF02021408    ABLF02021409    GFXV01003333    MBW15138.1    GFXV01003995    MBW15800.1    GEDC01020311    JAS16987.1    GL768121    EFZ12134.1    JH431845    LBMM01008239    KMQ89031.1    GL434335    EFN74999.1    QOIP01000007    RLU20668.1    KK107238    EZA54619.1    JR052898    AEY61810.1    GDRN01073504    JAI63382.1    GDRN01073508    JAI63379.1    KQ434960    KZC12683.1    GDRN01073505    JAI63381.1    GDRN01073507    JAI63380.1    KQ978684    KYN29306.1    GL445515    EFN89493.1    AJVK01000756    AJVK01000757    AJVK01000758    AJVK01000759    AJVK01000760    KQ981561    KYN39826.1    KQ977171    KYN05179.1    KQ982584    KYQ54431.1    QCYY01002627    ROT68842.1    KZ288226    PBC31869.1    KQ769179    OAD52957.1    CH981877    EDX15425.1    KQ435911    KOX68931.1    CH902619    EDV36898.1    KPU76493.1    KPU76494.1    GECL01000527    JAP05597.1    KQ414616    KOC68416.1    GEBQ01018189    JAT21788.1    CH963719    EDW71988.1    GEBQ01024054    JAT15923.1    GFTR01008996    JAW07430.1    KA644701    AFP59330.1    LJIG01001609    KRT85331.1    CM002911    KMY92020.1    KMY92021.1    CM000157    EDW89206.2    KRJ98276.1    GBBI01004017    JAC14695.1    AE013599    DS235222    EEB13528.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000053240    UP000007151    + More
UP000027135    UP000075883    UP000075901    UP000075920    UP000075900    UP000075884    UP000075885    UP000075880    UP000075886    UP000075882    UP000007062    UP000075840    UP000075903    UP000075902    UP000076407    UP000075881    UP000030765    UP000069940    UP000249989    UP000002320    UP000076408    UP000008820    UP000245037    UP000079169    UP000007266    UP000000673    UP000183832    UP000069272    UP000019118    UP000030742    UP000215335    UP000007819    UP000002358    UP000036403    UP000000311    UP000279307    UP000053097    UP000076502    UP000078492    UP000008237    UP000092462    UP000078541    UP000078542    UP000075809    UP000283509    UP000242457    UP000005203    UP000000304    UP000053105    UP000007801    UP000053825    UP000095300    UP000007798    UP000095301    UP000002282    UP000000803    UP000009046   

PRIDE

H9JF20    A1Z713   

Pfam

PF12624   Chorein_N        + More
PF06650   SHR-BD
PF16909   VPS13_C
PF16910   VPS13_mid_rpt
PF16908   VPS13
PF01027   Bax1-I
PF09333   ATG_C

Interpro

IPR031645   VPS13_C        + More
IPR031642   VPS13_mid_rpt       
IPR031646   VPS13_N2       
IPR026854   VPS13_N       
IPR009543   SHR-BD       
IPR026847   VPS13       
IPR006214   Bax_inhibitor_1-related       
IPR015412   Autophagy-rel_C       

ProteinModelPortal

H9JF20   A0A3S2LSU5   A0A2A4JAS4   A0A0N0PAP2   A0A194QM57   A0A1E1VZK4   + More
A0A1E1WNG3   A0A212EH99   A0A067RTP5   A0A182MPK1   A0A182SUD4   A0A182WB65   A0A182RA29   A0A182NLZ6   A0A182PLD4   A0A182IQ42   A0A182QNC8   A0A182LB90   Q5TSU0   A0A182HPA7   A0A182VBQ3   A0A182TV09   A0A182X4A3   A0A182JW81   A0A084WJG5   A0A1Q3FGM4   A0A1Q3FGD3   A0A182G3T1   B0WUG9   A0A182YFP8   A0A336L615   Q16SR9   A0A2P8Y000   A0A1S4E8Q6   A0A2H1W0S9   A0A2M3ZZF8   W4VRJ2   D6WCW1   W5J689   A0A2M4DRU1   A0A0P6JRN7   A0A1J1ITZ1   A0A2M4CVW7   A0A182FL84   V5GY02   N6U474   U4ULV9   A0A1Y1M0H6   A0A1L8DVL7   A0A232F955   J9K7I7   K7IXV4   A0A2H8TPG9   A0A2H8TP76   A0A1B6CUA0   E9J4Z2   T1J4H6   A0A0J7KFM8   E1ZV01   A0A3L8DLF8   A0A026WHS8   V9IL78   A0A0P4WPI9   A0A0P4W8G3   A0A154PLH2   A0A0P4WAQ3   A0A0P4W473   A0A151JQF4   E2B476   A0A1B0DB55   A0A151JY96   A0A195CYF9   A0A151X236   A0A3R7PJS0   A0A2A3EL42   A0A087ZQS4   A0A310S5Y6   B4NS47   A0A0N0BCF1   B3MHR1   A0A0P8XPG8   A0A0V0GCP3   A0A0L7RCF4   A0A1I8PU10   A0A1B6LDL1   B4MIP9   A0A1B6KWT9   A0A224XG50   A0A1I8NHV4   T1P7V0   A0A0T6BDC0   A0A0J9R7H7   B4P1S0   A0A023EZM1   A1Z713   E0VJH2  

KEGG

101737991    K19525 vacuolar protein sorting-associated protein 13A/C | (RefSeq) vacuolar protein sorting-associa

GO

GO:0006623   GO:0045053   GO:0005623   GO:0019898   GO:0016021   GO:0019538   GO:0031902  

PANTHER

PTHR16166  

Subcellular location

Late endosome membrane  

Length:

232

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00408999999999999

Exp number, first 60 AAs:

0.00396

Total prob of N-in:

0.10690

outside

1  -  232

 

 

Pi

226.79769

Theta

188.799998

Tajima's D

0.570197

CLR

0.059536

CSRT

0.532923353832308

Interpretation

Uncertain