Gene

KWMTBOMO04969  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007986

Annotation

PREDICTED:_phosphatidylinositol_4-kinase_beta_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr9(-):3730451-3786529      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 3.115

CDS

ATGTTGGAGGATGTTCCCGTGCACGGAAGTCGGTCAGACTCCCGCAATGGAAAGAGTACTATCCACCAGAGAAACCTCAGCTTGGATTTCAGGCATGTGACAGGCGCAGGAGGGCCGCCAGCGGGATGCGGTCATCAAAGGAACAGGTCCCTGGACTCTGTGCTCCAACGGATACCAGAAGACATGACACCAACTTCGCCGGAGGATGCACCTCTGCGACTCACTATCGAAGCGACGGTACCAAGATTGGCGCTACCCCCGGAAGTGCCGACAGGCTCAGACGACTCTGGTATTCACACGCCGCCCGATGACAACGAAGACGAGCGACCCCCGCTCCCGACAGCGGCGCGGTCTAGAGAAAGTCTTGATTCTGGAAATCCGGAAGACACAGAGAAACCTCCCGATCCCCCCGATACGATAGCAGAACCGACAACTACAGCTGGCACCAGCGTCGCAAGCACGTCCAAAAACAAAGACTCTCTGTTAAGACTATTCGAGAGTTCGTTGTTTGACATGAACATGGCAATAGAATATTTTCACAACTCCTCGGGCGTACAGACTTATCTGGCGAATAAGTTGTTTTCGTTTCCGCACGAGGATGTCGATTTTTATCTGCCGCAGCTGGCAACGATGTACATAGAGTTAGCCGACGTAGCGGAGGTGCTAAAGCCGTATTTGATTCATAGATGTAAACAGAGCACGGAGTTTTCGCTGCGACTCGTATGGTTGTTGACCGCGTTCGGTGGAGATTCGACAACGTCTAAAGCGATGAAGCTGAGAGAATCCATACTGGCCGAAAAGATTAGGCCGGCAGCGAAAAGAGGACATCACCGAACACAATCGGACGCTTCGGCGTTGAGAGTGTCGACGCCTCCTTGGAAATATTTAGGGGACTTGACATCTGGACGGGCCTTCGATAATGGTTGTGTTTGTGGGGAACAGTGTTCGTGCGACGCTCCCAGACTGGCACCGCATTTAGAGTTCATGTTGGCGCTAATGAATATCGGACGCCGGTTGGCCAGCGTCGCGGACAAGGAACGAAGGAATGGCCACCTCAGAGCTGAACTAGCGACTCTGAACCTGAATTTGCCGGCCAAAGTTTGGCTACCCCTATATCACAAGCCTCACTACGTGTTGAGGATATCACCGTACGCGGCCACGGTGCTCAATAGCAAAGATAAGGCTCCGTACATAATGTACGTGGAGGTACTAGAGACTGACGGGCACGAGCCTCTTCCTCCTCGCCAGCTGCCTCCAGCGCCACCAGCTCCCCACTCTCCCCCCATCAGACATACGAAGAGTGAGGAGAACCTCGTGCCTGAGTGGCCTGCGCTCTCCCTGTATTCGGCACTGGACGACGTGGACACCGGAGACTGCTGGAGTCATGACGACGATGAACTCAGCTCTCATTACGACCACAGAGCGCCCGCGCCCGACAGCGTGTCGCAGGTCTCGGCGGTTTCGGTTCTGTCCACGTCATCGTGCGGCAGCCGCGAGTCTGTGGCCGTGGTCGCCGGCGAGGTGCGCAGGAGGCTGGTCGACGCCACAGAAGCAGAAACCTTCAGACACGACCCCGCCGATCCGTCCGCTACCGCACTTAAGGAATCGTGGGAGAGCAAGCTGTGCCGCATCCGCGCCATGTCCCCGTACGGCGCGCTGTCGGGCTGGCGGCTGCTGGGCTGCATCGTGAAGGTGGGCGACGACCTGCGCCAGGAGCTGCTGGCCGCGCAGCTGCTGCGCCGCCTCACCGCCATCTGGCGCCACGAGCGCGTGCCGCTGGCGCTGCGCCCCTACGAGATCCTGTGTTTGGGCCGCGACACCGGACTCATACAACCGGTGCTGAACTCTGTGTCGCTGCACCAGATCAAGAAGCAGTCGGGGAAGTCCCTGCGCGCGTGGCTACAGCTAGAGCACGGCGCGCCCACCTCTGAAGGCTTCCTGCGCGCGCAAAGGAACTTCGTGGAATCCGTCGCCGCCTACGCGCTCGCCAGCTATCTGCTGCAACTCAAGGACCGGCACAACGGAAACATCTTATTGGACAGCGAAGGTCACATAATCCACATCGACTTCGGGTTCATATTCTCTACGTCACCGAAAAATCTTGGATTCGAAAGTTCACCGTTCAAATTGACACAGGAGTTCGTTGAGGTAATGGACGGCGAACACTCGGACATGTTTCAATACTTCAAGATATTGATCCTGCGCGGCCTCATCGCGGCGCGCAAGTACTGCGACCAGATCATACACATGGTCGAGCTGATGCGAATGAGCGGTCAGCTGGCGTGCCTCCGCAGTAGTAGCGTGGTGTCGTCGTTCCGCGCTCGCTTCCAGAGCGGCAAGACCGACCCGCAGCTGCAGGCGCTCGTCGACAGGCTCGTGCAGGACGCGCTCAACTCCATCTCCACCAGGCTCTACGACAACTACCAGTACCACACCAACGGGATACTGTGA

Protein

MLEDVPVHGSRSDSRNGKSTIHQRNLSLDFRHVTGAGGPPAGCGHQRNRSLDSVLQRIPEDMTPTSPEDAPLRLTIEATVPRLALPPEVPTGSDDSGIHTPPDDNEDERPPLPTAARSRESLDSGNPEDTEKPPDPPDTIAEPTTTAGTSVASTSKNKDSLLRLFESSLFDMNMAIEYFHNSSGVQTYLANKLFSFPHEDVDFYLPQLATMYIELADVAEVLKPYLIHRCKQSTEFSLRLVWLLTAFGGDSTTSKAMKLRESILAEKIRPAAKRGHHRTQSDASALRVSTPPWKYLGDLTSGRAFDNGCVCGEQCSCDAPRLAPHLEFMLALMNIGRRLASVADKERRNGHLRAELATLNLNLPAKVWLPLYHKPHYVLRISPYAATVLNSKDKAPYIMYVEVLETDGHEPLPPRQLPPAPPAPHSPPIRHTKSEENLVPEWPALSLYSALDDVDTGDCWSHDDDELSSHYDHRAPAPDSVSQVSAVSVLSTSSCGSRESVAVVAGEVRRRLVDATEAETFRHDPADPSATALKESWESKLCRIRAMSPYGALSGWRLLGCIVKVGDDLRQELLAAQLLRRLTAIWRHERVPLALRPYEILCLGRDTGLIQPVLNSVSLHQIKKQSGKSLRAWLQLEHGAPTSEGFLRAQRNFVESVAAYALASYLLQLKDRHNGNILLDSEGHIIHIDFGFIFSTSPKNLGFESSPFKLTQEFVEVMDGEHSDMFQYFKILILRGLIAARKYCDQIIHMVELMRMSGQLACLRSSSVVSSFRARFQSGKTDPQLQALVDRLVQDALNSISTRLYDNYQYHTNGIL

Similarity

Belongs to the PI3/PI4-kinase family.

Uniprot

A0A2W1BTL8   A0A2H1VT94   A0A194QKU1   A0A194QDS1   A0A212FLL2   A0A146KRY8   + More
A0A0K8SAJ8   D6X462   A0A0A9YXT1   A0A023F2H6   A0A224XJA5   A0A069DX32   A0A2P8Y5H7   A0A067QLB2   A0A2R7W4C9   T1IHS6   A0A0P5RML4   A0A0P5QGF9   A0A0P5MXL3   A0A0P5K416   A0A0P5SJF3   A0A164LGB7   A0A0P5CQE1   A0A0P5EBW3   A0A0P4Z5M5   A0A0N8C4E2   A0A1Y1LSC9   A0A0P6BUX1   A0A0P4ZYG3   A0A0N8CK46   A0A0P5Y2G1   A0A0P5EAD9   A0A1Y1LQE4   A0A0P5UL37   A0A0N8EPZ9   A0A0N8C9S8   A0A0P4Z7S4   E9J1K6   A0A195CP02   A0A0J7L901   E2AM46   A0A1S3HHC1   A0A1W4WH15   E9H0X8   A0A1E1X2D8   A0A147BS57   A0A131XWG7   A0A3S3PF60   V5HKJ4   A0A131YKX6   A0A224Z436   L7M037   A0A2T7PFL5   A0A0P5WB41   A0A1Z5L4N8   A0A131XIV9   A0A1D2MN43   A0A2R5LNV9   A0A210QMT2   A0A2L2Y9S4   A0A2P6LCB9   A0A0L8GQJ1   A0A3Q1J332   A0A0P5M7I2   A0A087TWF8   A0A3Q0RV42   W4YK59   A0A226DG11   A0A3B5A115   A0A3B4WBX5   A0A3Q1IZ07   A0A0F8ANZ4   A0A3B4UMU1   A0A147ALK0   A0A3P8T0Z7   A0A3Q2V9F6   A0A3P8Q245   V3ZYP0   A0A3B5PRL2   A0A3Q4GV66   A0A3B3BD70   A0A3Q1BXK5   A0A3B3BCB4   A0A3B4GCA7   A0A3Q2WJZ3   A0A3Q3SJ43   A0A3B4EH15   A0A3B5AL65   A0A3P9HZK1   A0A3Q2FTK0   H2N2X9   A0A3B3TUW3   H2SZZ4   A0A3Q3JR25   A0A3Q1G5A1   A0A146XPU0   A0A3B3SIX8   A0A1A7X800  

Pubmed

28756777    26354079    22118469    26823975    18362917    19820115    + More
25401762    25474469    26334808    29403074    24845553    28004739    21282665    20798317    21292972    28503490    29652888    25765539    26830274    28797301    25576852    28528879    28049606    27289101    28812685    26561354    25835551    23254933    23542700    25186727    29451363    17554307    21551351    29240929   

EMBL

KZ149974    PZC75976.1    ODYU01004324    SOQ44071.1    KQ461198    KPJ06014.1    + More
KQ459144    KPJ03703.1    AGBW02007748    OWR54617.1    GDHC01019365    GDHC01001507    JAP99263.1    JAQ17122.1    GBRD01015519    JAG50307.1    KQ971379    EEZ97712.1    GBHO01009229    GBHO01009228    JAG34375.1    JAG34376.1    GBBI01003207    JAC15505.1    GFTR01008213    JAW08213.1    GBGD01000627    JAC88262.1    PYGN01000904    PSN39507.1    KK853204    KDR09872.1    KK854317    PTY14584.1    JH430009    GDIQ01117474    JAL34252.1    GDIQ01117473    JAL34253.1    GDIQ01150354    JAL01372.1    GDIQ01215586    JAK36139.1    GDIQ01092430    JAL59296.1    LRGB01003134    KZS04083.1    GDIP01170966    JAJ52436.1    GDIP01150126    JAJ73276.1    GDIP01218269    JAJ05133.1    GDIQ01115923    JAL35803.1    GEZM01049748    JAV75881.1    GDIP01009821    JAM93894.1    GDIP01219562    JAJ03840.1    GDIP01123879    JAL79835.1    GDIP01063896    JAM39819.1    GDIP01145923    JAJ77479.1    GEZM01049747    JAV75882.1    GDIP01111380    JAL92334.1    GDIQ01005276    JAN89461.1    GDIQ01100835    JAL50891.1    GDIP01218270    JAJ05132.1    GL767674    EFZ13183.1    KQ977513    KYN02212.1    LBMM01000206    KMR04490.1    GL440704    EFN65504.1    GL732582    EFX74536.1    GFAC01005761    JAT93427.1    GEGO01001798    JAR93606.1    GEFM01005875    JAP69921.1    NCKU01005431    NCKU01001796    RWS04579.1    RWS11228.1    GANP01010490    JAB73978.1    GEDV01009831    JAP78726.1    GFPF01010545    MAA21691.1    GACK01007358    JAA57676.1    PZQS01000004    PVD32190.1    GDIP01089729    JAM13986.1    GFJQ02004597    JAW02373.1    GEFH01002124    JAP66457.1    LJIJ01000818    ODM94358.1    GGLE01006982    MBY11108.1    NEDP02002776    OWF50033.1    IAAA01011331    IAAA01011332    LAA04901.1    MWRG01000386    PRD36223.1    KQ420917    KOF78880.1    GDIQ01171546    JAK80179.1    KK117072    KFM69447.1    AAGJ04105879    AAGJ04105880    AAGJ04105881    AAGJ04105882    AAGJ04105883    LNIX01000019    OXA44482.1    KQ041575    KKF24722.1    GCES01006917    JAR79406.1    KB203188    ESO86106.1    GCES01042220    JAR44103.1    HADW01012539    SBP13939.1   

Proteomes

UP000053240    UP000053268    UP000007151    UP000007266    UP000245037    UP000027135    + More
UP000076858    UP000078542    UP000036403    UP000000311    UP000085678    UP000192223    UP000000305    UP000285301    UP000245119    UP000094527    UP000242188    UP000053454    UP000265040    UP000054359    UP000261340    UP000007110    UP000198287    UP000261400    UP000261360    UP000261420    UP000265080    UP000264840    UP000265100    UP000030746    UP000002852    UP000261580    UP000261560    UP000257160    UP000261460    UP000261640    UP000261440    UP000265200    UP000265020    UP000001038    UP000261500    UP000005226    UP000261600    UP000257200    UP000261540   

PRIDE

V5HKJ4    L7M037   

Pfam

PF00454   PI3_PI4_kinase

Interpro

IPR036940   PI3/4_kinase_cat_sf        + More
IPR018936   PI3/4_kinase_CS       
IPR000403   PI3/4_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR015433   PI_Kinase       
IPR001263   PI3K_accessory_dom       
IPR016024   ARM-type_fold       

SUPFAM

SSF56112   SSF56112        + More
SSF48371   SSF48371       

Gene 3D

1.10.1070.11    

ProteinModelPortal

A0A2W1BTL8   A0A2H1VT94   A0A194QKU1   A0A194QDS1   A0A212FLL2   A0A146KRY8   + More
A0A0K8SAJ8   D6X462   A0A0A9YXT1   A0A023F2H6   A0A224XJA5   A0A069DX32   A0A2P8Y5H7   A0A067QLB2   A0A2R7W4C9   T1IHS6   A0A0P5RML4   A0A0P5QGF9   A0A0P5MXL3   A0A0P5K416   A0A0P5SJF3   A0A164LGB7   A0A0P5CQE1   A0A0P5EBW3   A0A0P4Z5M5   A0A0N8C4E2   A0A1Y1LSC9   A0A0P6BUX1   A0A0P4ZYG3   A0A0N8CK46   A0A0P5Y2G1   A0A0P5EAD9   A0A1Y1LQE4   A0A0P5UL37   A0A0N8EPZ9   A0A0N8C9S8   A0A0P4Z7S4   E9J1K6   A0A195CP02   A0A0J7L901   E2AM46   A0A1S3HHC1   A0A1W4WH15   E9H0X8   A0A1E1X2D8   A0A147BS57   A0A131XWG7   A0A3S3PF60   V5HKJ4   A0A131YKX6   A0A224Z436   L7M037   A0A2T7PFL5   A0A0P5WB41   A0A1Z5L4N8   A0A131XIV9   A0A1D2MN43   A0A2R5LNV9   A0A210QMT2   A0A2L2Y9S4   A0A2P6LCB9   A0A0L8GQJ1   A0A3Q1J332   A0A0P5M7I2   A0A087TWF8   A0A3Q0RV42   W4YK59   A0A226DG11   A0A3B5A115   A0A3B4WBX5   A0A3Q1IZ07   A0A0F8ANZ4   A0A3B4UMU1   A0A147ALK0   A0A3P8T0Z7   A0A3Q2V9F6   A0A3P8Q245   V3ZYP0   A0A3B5PRL2   A0A3Q4GV66   A0A3B3BD70   A0A3Q1BXK5   A0A3B3BCB4   A0A3B4GCA7   A0A3Q2WJZ3   A0A3Q3SJ43   A0A3B4EH15   A0A3B5AL65   A0A3P9HZK1   A0A3Q2FTK0   H2N2X9   A0A3B3TUW3   H2SZZ4   A0A3Q3JR25   A0A3Q1G5A1   A0A146XPU0   A0A3B3SIX8   A0A1A7X800  

PDB

5EUQ     E-value=3.14272e-71,     Score=685

KEGG

101741374    K19801 phosphatidylinositol 4-kinase B [EC:2.7.1.67] | (RefSeq) phosphatidylinositol 4-kinase beta

PATHWAY

00562    Inositol phosphate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04070    Phosphatidylinositol signaling system - Bombyx mori (domestic silkworm)

GO

GO:0046854   GO:0016301   GO:0048015   GO:0005737   GO:0004430   GO:0016020   GO:0016021   GO:0060872   GO:0005488   GO:0005524   GO:0005634   GO:0003676   GO:0007166   GO:0006032   GO:0005515   GO:0016742   GO:0003824  

PANTHER

PTHR10048  

Length:

816

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00759999999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00007

outside

1  -  816

 

 

Pi

26.690753

Theta

186.131277

Tajima's D

-1.747569

CLR

165.75897

CSRT

0.0343482825858707

Interpretation

Possibly Positive selection