Gene

KWMTBOMO04968  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008085

Annotation

ATP-dependent_RNA_helicase_DDX54_[Papilio_xuthus]

Location

Bomo_Chr9(+):3714350-3725979      View in EpiBrowser

Full name

ATP-dependent RNA helicase       + More
ATP-dependent RNA helicase DDX54      

Location in the cell

Mitochondrial   Reliability : 2.389

CDS

ATGTTAAAACCTAAAGAATTAGATGATCATCTGCCGGGTTTCGATGCCCCTAAAGCAGATGAGCCTCAAAATGAACCCAAAAACAACCAGAAGAAAAAGAAGAGTTCGGGTGCTTTTCAATCAATGGGCCTAAGTTTTCCTGTTTTAAAAGGAATCACGAAACGGGGTTACAAACAACCAACACCTATACAACGTAAGACCATACCAATAGCATTGACCGGGAAAGATGTTGTTGCAATGGCCCGAACTGGGTCCGGAAAAACAGCTTGTTTTGTCCTCCCTATCCTTGAGAAACTTCTTGTTCCGAACAACAAACCTACACCTGGAAAGAATTTGAGGGCATTAATTCTCTCACCAACTAGAGAACTCGCATTACAGACATTAAGATTTGTGAGGGAGCTAGGAAAATTCACTGGATTAACGAGTGCAGCTATTCTTGGTGGAGAGTCCATTGAGCAGCAGTTTAATGTGATGTCTGGCTCTTCTCCAGACATAGTTGTTGCAACACCTGGGCGCTTCTTACACATCTGCATTGAGATGTGCTTAAAGTTAGACAACATCAAAATAGTTGTTTTTGATGAAGCTGACCGACTATTTGAGCTTGGTTTCGGTGAGCAATTACAAGAGATCTGTGCTCGTCTCCCTTCTAGTCGTCAAACGTTATTATTCTCTGCAACACTACCTAAAATGCTAGTAGAATTTGCGAGGGCTGGACTATCAGATCCCACCTTGATAAGATTAGATGTTGATTGGAAATTACCTTCAACATTATGGCTGGGATGGATATCAGTTAGGGCTGAATTGAAAACGGCAGCCCTGTTGATTCTATTAGACAAAGTATTAACTCCAACAACACCCCAAGCAGTTGTCTTTGCTGCTACGAAACATCATGTTGAGTATTTACATTTGATTCTACAACAAGCCGGTATAAGTTCAACATATGCGTATTCAGGCCTTGATCCGTCAGCCCGTAAGATAGCTCTAGGACGGTTTACCAATAAGAAGTGTTCTGTTCTAATAGTAACGGATGTGGCAGCCAGAGGTCTAGACTTACCTGCATTGGATACAGTCATTAATTACAACTTTCCGGCGAAACCCAAACTCTTCGTCCACAGAGTTGGTCGCAGTGCCAGAGCGGGTCGAGCGGGTCGGGCCTTCTCCCTGGTGGCTGCGGAAGACGTGGCCCACTTGTTGGATCTGCAGCTGTTCTTGGGCACCACGCTGGGGAGAGTGGACGAGAGCGCGGGGCGGGGGGCCGCCTGCGCCAGCGGAGTGTGGGGGGCGTTGCCCGCAGAACAGCTGGAACTTCGACATCAGGACGTTATGGCCTGGGAGAAGAACTACTCTGAAATTGAGGAGGCGGCTCGTACGTGCGCCCGTGGACTGCAGCAGTACGTGCGGTGGCGCGAGGCGGCCTCCGCGGAGGGCAACAGGCGCGCCAAGCTGACCGAAGCGCCCACGCAGCCGCACCCCTTCCTCACCGACGGCGCCCCGGACTCCGCCGCGGTACTCGTGGATCAGATCAAGAACTACACACCTAAAGGGACAATATTGGAGTTGTCGGCTAAAAACGATTCACCGATGTATTTAGCGATGAAAGCCAAGAAGCTCGCACACGGCAGAACTGTCGAGAAGACGAGACAAAACAAAAAGCTACAGGCCGAAGGTAAACTTGATGATATCGTTACTGCCGTTAAATCTAAGAAGAAAAAGAAGGGACCAGTGCGAGATGAGAACTACATACCGCATCAAGCAAGCGACCAGCACACTGAAACAGGCATGGCGGTGAACTTCAGCGCGGGCGCGGAGCACGCCCAGCTGGAGCTGCGAGCCGACAGCGGGGACGCCGAGCGCGCGCAGCGGAACGTCATGCGCTGGGACAGGAAGCGGAAGAAGATGGTGCACGTTGACCCCGACGGCGGACGCAAGATGATTCGTACTGAGAGCGGGTTCCGGGTCCCGGCTTCGTTCCGCAGCGGCCGCTTCGACGACTGGAAAAAACGCAACCTCGCGCACGACCACTCCGACGACGAACCGCAAGCACAAACAAATAAAAGGAAACCAGCGTCGGAGTTCCGTCCGCACTGGGTGAAGCACAACGAACGCGTAGCGAAAAAAGCGGCCGAGTCCAAGTCGCGCGAGTTCAGAGACAAGCAGCAGATCGTCAAGGAGCGCATGCGGAAGGACAAGATTAAACAGAAACTCAAGTTCAAAGGGAACAAGAAGAAAAACAAAAGGAAAAAATAA

Protein

MLKPKELDDHLPGFDAPKADEPQNEPKNNQKKKKSSGAFQSMGLSFPVLKGITKRGYKQPTPIQRKTIPIALTGKDVVAMARTGSGKTACFVLPILEKLLVPNNKPTPGKNLRALILSPTRELALQTLRFVRELGKFTGLTSAAILGGESIEQQFNVMSGSSPDIVVATPGRFLHICIEMCLKLDNIKIVVFDEADRLFELGFGEQLQEICARLPSSRQTLLFSATLPKMLVEFARAGLSDPTLIRLDVDWKLPSTLWLGWISVRAELKTAALLILLDKVLTPTTPQAVVFAATKHHVEYLHLILQQAGISSTYAYSGLDPSARKIALGRFTNKKCSVLIVTDVAARGLDLPALDTVINYNFPAKPKLFVHRVGRSARAGRAGRAFSLVAAEDVAHLLDLQLFLGTTLGRVDESAGRGAACASGVWGALPAEQLELRHQDVMAWEKNYSEIEEAARTCARGLQQYVRWREAASAEGNRRAKLTEAPTQPHPFLTDGAPDSAAVLVDQIKNYTPKGTILELSAKNDSPMYLAMKAKKLAHGRTVEKTRQNKKLQAEGKLDDIVTAVKSKKKKKGPVRDENYIPHQASDQHTETGMAVNFSAGAEHAQLELRADSGDAERAQRNVMRWDRKRKKMVHVDPDGGRKMIRTESGFRVPASFRSGRFDDWKKRNLAHDHSDDEPQAQTNKRKPASEFRPHWVKHNERVAKKAAESKSREFRDKQQIVKERMRKDKIKQKLKFKGNKKKNKRKK

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Similarity

Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.

Uniprot

A0A2W1BW47   A0A2A4J9A3   A0A194QE00   A0A2H1VTB7   A0A212FLP5   S4PEY8   + More
A0A194QKB4   A0A3S2N623   A0A2A4JAU0   A0A195DZ19   A0A195ASZ0   A0A195CN85   A0A195FIN9   A0A158P3U4   E9J1K7   A0A151X1D7   A0A2J7PF04   A0A1Y1LB33   A0A026W6R2   F4WKY0   A0A0M9A3H3   A0A087ZPK1   A0A1B6FMG5   A0A2A3EUU4   A0A1B6L8V3   A0A154P1S1   E2AM45   E0VQ55   A0A023F200   A0A0J7L8J3   A0A0C9R8M7   K7J2Z7   T1I047   A0A0V0G866   A0A139WB42   A0A0L7QZN4   A0A232FIL8   A0A069DW61   A0A224XKB7   A0A1B6CB73   E2C7I6   U4U281   A0A1I8NL41   A0A1I8Q710   A0A1I8Q6Y7   A0A1S3HBS9   A0A0K8T610   Q8SY39   A0A0A9WEU9   B3NEP1   B4QEZ2   A0A226EK89   A7RST4   A0A1J1J9R9   B4HVF1   A0A0K2TUK3   B4K7A0   B3M8Z0   N6UFA2   B4PC53   A0A2H8TQY9   A0A2S2PPP4   J9JS39   A0A1B0CH93   A0A2S2QE53   A0A293MXS0   A0A1B0BRA4   D3ZHY6   A0A1W4Z5J9   H3AKH6   A0A1D1VTK7   A0A1X7ULV9   A0A224YS12   H0WCG4   A0A250YLI6   A0A0P7TFZ0   W5MPL9   A0A131XC94   A0A151N5A2   A0A1U7RF51   A0A3L8SCF7   U3JZ66   M3ZT06   A0A2I4CVV7   A0A1A6FZ34   A0A2Y9KNP7   A0A1D2NBX4   A0A218V3H5   A0A3B4CD54   A0A3Q2PSF5   A0A1V4JSL5   U3CWT5   V3ZA05   A0A3P4S3V6   V9KC54   U3DSV4   A0A146N091  

EC Number

3.6.4.13

Pubmed

28756777    26354079    22118469    23622113    21347285    21282665    + More
28004739    24508170    30249741    21719571    20798317    20566863    25474469    20075255    18362917    19820115    28648823    26334808    23537049    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25401762    17994087    22936249    17615350    17550304    15057822    22673903    9215903    27649274    28797301    21993624    28087693    28049606    22293439    30282656    23542700    27289101    25243066    23254933    24402279   

EMBL

KZ149974    PZC75973.1    NWSH01002321    PCG68531.1    KQ459144    KPJ03702.1    + More
ODYU01004324    SOQ44070.1    AGBW02007748    OWR54619.1    GAIX01004282    JAA88278.1    KQ461198    KPJ06013.1    RSAL01000337    RVE42440.1    PCG68532.1    KQ980044    KYN18076.1    KQ976746    KYM75333.1    KQ977513    KYN02211.1    KQ981523    KYN40530.1    ADTU01008551    GL767674    EFZ13254.1    KQ982601    KYQ54001.1    NEVH01026086    PNF14916.1    GEZM01062667    GEZM01062666    JAV69550.1    KK107373    QOIP01000004    EZA51658.1    RLU23414.1    GL888206    EGI65222.1    KQ435774    KOX75099.1    GECZ01018415    JAS51354.1    KZ288186    PBC34831.1    GEBQ01019936    JAT20041.1    KQ434787    KZC05284.1    GL440704    EFN65503.1    DS235389    EEB15511.1    GBBI01003120    JAC15592.1    LBMM01000206    KMR04491.1    GBYB01003033    GBYB01004480    JAG72800.1    JAG74247.1    ACPB03019371    GECL01001793    JAP04331.1    KQ971374    KYB25129.1    KQ414679    KOC64058.1    NNAY01000174    OXU30308.1    GBGD01000586    JAC88303.1    GFTR01007945    JAW08481.1    GEDC01026571    GEDC01008684    JAS10727.1    JAS28614.1    GL453383    EFN76062.1    KB631815    ERL86393.1    GBRD01004965    JAG60856.1    AY075397    AE014296    AAL68229.1    AAN11439.1    GBHO01038583    GBHO01038581    JAG05021.1    JAG05023.1    CH954178    EDV50036.1    CM000362    CM002912    EDX07019.1    KMY96638.1    LNIX01000003    OXA57618.1    DS469535    EDO45469.1    CVRI01000075    CRL08620.1    CH480817    EDW49916.1    HACA01011725    CDW29086.1    CH933806    EDW14224.1    CH902618    EDV38934.1    APGK01029188    KB740727    ENN79306.1    CM000159    EDW92708.2    GFXV01004802    MBW16607.1    GGMR01018821    MBY31440.1    ABLF02027827    AJWK01012118    AJWK01012119    GGMS01006823    MBY76026.1    GFWV01020875    MAA45603.1    JXJN01019010    AABR07036387    AFYH01161647    AFYH01161648    AFYH01161649    AFYH01161650    AFYH01161651    AFYH01161652    AFYH01161653    AFYH01161654    AFYH01161655    BDGG01000009    GAV03543.1    GFPF01006235    MAA17381.1    AAKN02056159    GFFW01000285    JAV44503.1    JARO02011672    KPP59736.1    AHAT01005287    AHAT01005288    GEFH01004589    JAP63992.1    AKHW03004053    KYO31779.1    QUSF01000030    RLV99955.1    AGTO01000187    LZPO01110310    OBS58825.1    LJIJ01000096    ODN02763.1    MUZQ01000064    OWK60260.1    LSYS01006629    OPJ74707.1    GAMR01009965    GAMP01003988    JAB23967.1    JAB48767.1    KB202823    ESO87808.1    CYRY02046229    VCX41884.1    JW862960    AFO95477.1    GAMT01004132    GAMS01005654    GAMS01005652    GAMQ01000068    JAB07729.1    JAB17482.1    JAB41783.1    GCES01161866    JAQ24456.1   

Proteomes

UP000218220    UP000053268    UP000007151    UP000053240    UP000283053    UP000078492    + More
UP000078540    UP000078542    UP000078541    UP000005205    UP000075809    UP000235965    UP000053097    UP000279307    UP000007755    UP000053105    UP000005203    UP000242457    UP000076502    UP000000311    UP000009046    UP000036403    UP000002358    UP000015103    UP000007266    UP000053825    UP000215335    UP000008237    UP000030742    UP000095301    UP000095300    UP000085678    UP000000803    UP000008711    UP000000304    UP000198287    UP000001593    UP000183832    UP000001292    UP000009192    UP000007801    UP000019118    UP000002282    UP000007819    UP000092461    UP000092460    UP000002494    UP000192224    UP000008672    UP000186922    UP000007879    UP000005447    UP000034805    UP000018468    UP000050525    UP000189705    UP000276834    UP000016665    UP000002852    UP000192220    UP000092124    UP000248482    UP000094527    UP000197619    UP000261440    UP000265000    UP000190648    UP000030746   

PRIDE

Q8SY39    D3ZHY6   

Pfam

PF08147   DBP10CT        + More
PF00271   Helicase_C
PF00270   DEAD
PF00858   ASC
PF03109   ABC1

Interpro

IPR014001   Helicase_ATP-bd        + More
IPR000629   RNA-helicase_DEAD-box_CS       
IPR001650   Helicase_C       
IPR014014   RNA_helicase_DEAD_Q_motif       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR033517   DDX54/DBP10       
IPR012541   DBP10_C       
IPR027417   P-loop_NTPase       
IPR001873   ENaC       
IPR011009   Kinase-like_dom_sf       
IPR004147   UbiB_dom       
IPR000719   Prot_kinase_dom       

SUPFAM

SSF52540   SSF52540        + More
SSF56112   SSF56112       

CDD

cd00079  HELICc

ProteinModelPortal

A0A2W1BW47   A0A2A4J9A3   A0A194QE00   A0A2H1VTB7   A0A212FLP5   S4PEY8   + More
A0A194QKB4   A0A3S2N623   A0A2A4JAU0   A0A195DZ19   A0A195ASZ0   A0A195CN85   A0A195FIN9   A0A158P3U4   E9J1K7   A0A151X1D7   A0A2J7PF04   A0A1Y1LB33   A0A026W6R2   F4WKY0   A0A0M9A3H3   A0A087ZPK1   A0A1B6FMG5   A0A2A3EUU4   A0A1B6L8V3   A0A154P1S1   E2AM45   E0VQ55   A0A023F200   A0A0J7L8J3   A0A0C9R8M7   K7J2Z7   T1I047   A0A0V0G866   A0A139WB42   A0A0L7QZN4   A0A232FIL8   A0A069DW61   A0A224XKB7   A0A1B6CB73   E2C7I6   U4U281   A0A1I8NL41   A0A1I8Q710   A0A1I8Q6Y7   A0A1S3HBS9   A0A0K8T610   Q8SY39   A0A0A9WEU9   B3NEP1   B4QEZ2   A0A226EK89   A7RST4   A0A1J1J9R9   B4HVF1   A0A0K2TUK3   B4K7A0   B3M8Z0   N6UFA2   B4PC53   A0A2H8TQY9   A0A2S2PPP4   J9JS39   A0A1B0CH93   A0A2S2QE53   A0A293MXS0   A0A1B0BRA4   D3ZHY6   A0A1W4Z5J9   H3AKH6   A0A1D1VTK7   A0A1X7ULV9   A0A224YS12   H0WCG4   A0A250YLI6   A0A0P7TFZ0   W5MPL9   A0A131XC94   A0A151N5A2   A0A1U7RF51   A0A3L8SCF7   U3JZ66   M3ZT06   A0A2I4CVV7   A0A1A6FZ34   A0A2Y9KNP7   A0A1D2NBX4   A0A218V3H5   A0A3B4CD54   A0A3Q2PSF5   A0A1V4JSL5   U3CWT5   V3ZA05   A0A3P4S3V6   V9KC54   U3DSV4   A0A146N091  

PDB

5IVL     E-value=4.40298e-52,     Score=520

KEGG

100862825    K14808 ATP-dependent RNA helicase DDX54/DBP10 [EC:3.6.4.13] | (RefSeq) ATP-dependent RNA helicase DD

GO

GO:0005524   GO:0003723   GO:0004004   GO:0005730   GO:0005272   GO:0016021   GO:0005634   GO:0004672   GO:0004386   GO:0006396   GO:0005794   GO:0003714   GO:0030331   GO:0003676   GO:0007166   GO:0006032   GO:0005515   GO:0016742   GO:0003824  

PANTHER

PTHR24031:SF292  

Subcellular location

  

Length:

748

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00678999999999998

Exp number, first 60 AAs:

0.0029

Total prob of N-in:

0.00079

outside

1  -  748

 

 

Pi

191.157738

Theta

160.240009

Tajima's D

-1.720107

CLR

1697.980891

CSRT

0.0369981500924954

Interpretation

Possibly Positive selection