Gene

KWMTBOMO04964

Pre Gene Modal

BGIBMGA007990

Annotation

PREDICTED:_protein_ST7_homolog_[Neodiprion_lecontei]

Location

Bomo_Chr9(-):3581656-3585218      View in EpiBrowser

Full name

Suppressor of tumorigenicity 7 protein      

Alternative Name

Protein FAM4A1
Protein HELG

Location in the cell

PlasmaMembrane   Reliability : 1.115

CDS

ATGTGGGACACAAACGCATATTTGAGCGCATTGACGCCTAAATTCTATGTAGCATTAACAGGCACTTCGTCTTTGATATCAGGACTCATTCTTATTTTCGAATGGTGGTATTTTAGAACATACGGTACCTCATTTATAGAACAAGTATCGCTATCACATCTTGGACCATGGTTAGGTGGCGGCAATGAGACGGATAATTCAAATACTAATACAAACAATACAGCTAGTAATGAATGCAAAGTTTGGCGGAATCCTATGGCTTTACTGCGAGGCGCTGAGTATGGGAGACTTTGGAGTGCCGCAAGGCGAGCTCCACTCACCTATTACGATATGAATTTATCAGCTCAAGACCATCAGGCCTGGTTTAGCTGTGGAGGAGATCAAAGTCCTGTGGAAGAAGCAATGAATCGTGCATGGCGTGAACGTGAACCTACAGCCCGTGTGGCAGCTGCTCGCACTGCACTAGCTAGAGATCCAGACTGTGCTGCTGCATTGTTGTTACTGGCAGAGGAAGATTCACCGACAGTACAAGAGGCTGAACGTGTACTGAAGAGAGCTTGGCGAGCAGCTGAGGCGTCTTGGAGAGCGCACGCAGCCGCTGGATCTGCATATGCTAGCGCAGCCCGACGCGACGCGGCCGTGCTAGCCCACGTCAAGCGTCGAGTTGCTATGTGCGCTCGTCGTCTCGGCAAACTCCGCGACGCCGCTAGAATGTTCCGCGAACTAACGCGAGATGCTCCTCCCGCCCTCCACGCAATGTCACTCCATGAAAACTTGATAGAGGTGCTGTTGGAGCAGAGGCTGTATGCGGACGCGGCTGCTGTTGTTGCGAGATTTGAAGACGCAGGTGCTCCGCCTTCAGCAGCGTTATTGTACACGGCCGCGTTGTTGAGAGCACGTGCTGCCGTCGGCGTTGGTGCACGTCCCGGAGCAGAGGTCATTGCTCTGGAGGCAATACGTCGCGCTATCGAGTTCAATCCTCACGTGCCCGAGTACCTATTAGAATTGCGCGCTTTAACTTTACCACCTGAGCACGTGTTGCGTCGCGGCGACAGCGAAGCGGTCGCGTACGCGTTTTTCCACTTGCGACACTGGCGGAACGCGGAGGGCGCGCTGCGGCTGGTGGCGGCGGCGTGGGCGGGCGCGGAGCGGGCGGGCGCGGGGGCGGGCGCGGGGTGCGCGGCGTGCGCGGACCGCGAGCTGCTTGCGCCGCACCACGCCATGTCCGCATTCCCGCGCCGCCGCGCCGCGCTCCTGCCACTGGCGGCAGCGCTGTGCGCGGGCTGCGCCGTGCTGGCGCTGGCGGCGCACCGGTGGCCGGCGCATGCGCACGCGCTTCTCGACCCGCGCCGCCTGCACTCCCTGTTGGCGGCCGTCTGA

Protein

MWDTNAYLSALTPKFYVALTGTSSLISGLILIFEWWYFRTYGTSFIEQVSLSHLGPWLGGGNETDNSNTNTNNTASNECKVWRNPMALLRGAEYGRLWSAARRAPLTYYDMNLSAQDHQAWFSCGGDQSPVEEAMNRAWREREPTARVAAARTALARDPDCAAALLLLAEEDSPTVQEAERVLKRAWRAAEASWRAHAAAGSAYASAARRDAAVLAHVKRRVAMCARRLGKLRDAARMFRELTRDAPPALHAMSLHENLIEVLLEQRLYADAAAVVARFEDAGAPPSAALLYTAALLRARAAVGVGARPGAEVIALEAIRRAIEFNPHVPEYLLELRALTLPPEHVLRRGDSEAVAYAFFHLRHWRNAEGALRLVAAAWAGAERAGAGAGAGCAACADRELLAPHHAMSAFPRRRAALLPLAAALCAGCAVLALAAHRWPAHAHALLDPRRLHSLLAAV

Description

May act as a tumor suppressor.

Similarity

Belongs to the ST7 family.

Keywords

Alternative splicing   Complete proteome   Glycoprotein   Membrane   Phosphoprotein   Polymorphism   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Suppressor of tumorigenicity 7 protein
splice variant  In isoform 6.
sequence variant  In dbSNP:rs201219065.

Uniprot

H9JEP3   A0A2H1VXJ1   A0A212F0A0   A0A0P6K139   B0X5U6   A0A182H2N3   + More
A0A0M9A177   A0A0J7P3H8   W5JH00   A0A182FF79   A0A0C9QAR2   E2C7I9   A0A0L7QZS4   A0A3Q1LPG4   E2AM47   A0A1Y1K8J2   A0A146LX50   A0A151WF29   A0A195ATJ9   E9J1K4   F4WKY2   A0A158P3U2   A0A1W4WT20   A0A087ZPH9   A0A2A3EUL2   A0A1Q3F603   A0A336MN84   D6X3H2   A0A154P0B8   A0A026W7Q9   A0A1B0D8Q0   K7J2Z5   A0A232ELU8   A0A1B0CH92   A0A182QKR1   A0A195FJF0   A0A195DZM8   A0A2J7PWR6   A0A067R7W1   A0A182U482   Q7QJH8   A0A182I3E7   A0A182X3M2   A0A182V8I8   A0A182KRF8   A0A182XYZ8   A0A195CNC2   A0A0P4ZEH3   A0A2J7PWR1   A0A182NHR8   A0A164K2P0   A0A182WJ49   A0A0N8A0T2   E9HDV1   A0A0P5TNE7   A0A0P5TK60   A0A2P2I6C2   A0A1B6D6N6   A0A0P6AB91   A0A0P5WUS8   A0A0P5GFE4   A0A1B6M4L4   A0A3R7PEQ7   A0A1B6EYG7   A0A0N7ZJE3   A0A0P4XWZ4   A0A0P5MBD4   A0A0P4W9U9   J3JUX9   A0A1D2MSL3   A0A131Z2E6   L7M774   A0A1E1XDQ3   A0A023GKY1   G3MM84   A0A2R5LKS9   A0A293N6J5   C3YPI6   A0A131XJB9   A0A131Y009   A0A3B3Q998   B7PBY6   A0A0P6I0M7   W5MW97   T1IZ41   W5LB12   A0A3Q3JA04   G3WY21   A0A3B3CDA4   V9KNM4   A0A3B4G615   A0A3P8QKW0   A0A3P9BBA1   A0A2R8ZXV5   Q9NRC1-3   A0A3P8WX59   A0A3Q2VGJ7   A0A3P9HTS5   A0A1A8CUS2   A0A3B4AZN1  

Pubmed

19121390    22118469    26999592    26483478    20920257    23761445    + More
20798317    19393038    28004739    26823975    21282665    21719571    21347285    18362917    19820115    24508170    30249741    20075255    28648823    24845553    12364791    14747013    17210077    20966253    25244985    21292972    22516182    23537049    27289101    26830274    25576852    28503490    22216098    18563158    28049606    29240929    25329095    21709235    29451363    24402279    25186727    22722832    10889047    11279520    14702039    12853948    12690205    15489334    12213198    17974005    16474848    18691976    11726923    24487278    17554307    25463417   

EMBL

BABH01023622    ODYU01005056    SOQ45559.1    AGBW02011129    OWR47178.1    GDUN01000188    + More
JAN95731.1    DS232396    EDS41077.1    JXUM01023872    JXUM01048439    KQ561562    KQ560673    KXJ78166.1    KXJ81337.1    KQ435774    KOX75097.1    LBMM01000206    KMR04489.1    ADMH02001422    ETN62598.1    GBYB01011578    JAG81345.1    GL453383    EFN76065.1    KQ414679    KOC64056.1    GL440704    EFN65505.1    GEZM01089028    JAV57759.1    GDHC01006436    JAQ12193.1    KQ983227    KYQ46460.1    KQ976746    KYM75335.1    GL767674    EFZ13204.1    GL888206    EGI65224.1    ADTU01008551    KZ288186    PBC34829.1    GFDL01012055    JAV22990.1    UFQT01000829    SSX27448.1    KQ971374    EEZ97404.1    KQ434787    KZC05282.1    KK107373    QOIP01000004    EZA51661.1    RLU23412.1    AJVK01027636    AJVK01027637    NNAY01003493    OXU19334.1    AJWK01012118    AXCN02000377    KQ981523    KYN40528.1    KQ980044    KYN18079.1    NEVH01020869    PNF20772.1    KK852819    KDR15604.1    AAAB01008807    EAA04741.2    APCN01000207    KQ977513    KYN02213.1    GDIP01213787    JAJ09615.1    PNF20774.1    LRGB01003380    KZS02893.1    GDIP01193681    JAJ29721.1    GL732625    EFX70092.1    GDIP01125188    JAL78526.1    GDIP01125187    JAL78527.1    IACF01003822    LAB69430.1    GEDC01015950    JAS21348.1    GDIP01031950    JAM71765.1    GDIP01081789    JAM21926.1    GDIQ01247540    JAK04185.1    GEBQ01009117    JAT30860.1    QCYY01002638    ROT68745.1    GECZ01026829    GECZ01019905    GECZ01015617    GECZ01004588    JAS42940.1    JAS49864.1    JAS54152.1    JAS65181.1    GDIP01239593    JAI83808.1    GDIP01239592    JAI83809.1    GDIQ01166622    JAK85103.1    GDRN01075207    GDRN01075203    JAI63092.1    BT127044    KB632345    AEE62006.1    ERL93079.1    LJIJ01000593    ODM96023.1    GEDV01003642    JAP84915.1    GACK01004908    JAA60126.1    GFAC01001813    JAT97375.1    GBBM01000877    JAC34541.1    JO842985    AEO34602.1    GGLE01005985    MBY10111.1    GFWV01023312    MAA48039.1    GG666538    EEN57770.1    GEFH01002950    JAP65631.1    GEFM01003958    JAP71838.1    ABJB010842447    ABJB011083945    DS680117    EEC04108.1    GDIQ01011317    JAN83420.1    AHAT01014313    AFFK01020382    AEFK01176138    AEFK01176139    AEFK01176140    JW867318    AFO99835.1    AJFE02025916    AJFE02025917    AJFE02025918    AJFE02025919    AJFE02025920    AF234882    AF234883    AY009152    AY009153    AK093212    CH236947    AC002542    CH471070    BC030954    BC075855    AF415174    CR936656    AJ277291    HADZ01019611    SBP83552.1   

Proteomes

UP000005204    UP000007151    UP000002320    UP000069940    UP000249989    UP000053105    + More
UP000036403    UP000000673    UP000069272    UP000008237    UP000053825    UP000009136    UP000000311    UP000075809    UP000078540    UP000007755    UP000005205    UP000192223    UP000005203    UP000242457    UP000007266    UP000076502    UP000053097    UP000279307    UP000092462    UP000002358    UP000215335    UP000092461    UP000075886    UP000078541    UP000078492    UP000235965    UP000027135    UP000075902    UP000007062    UP000075840    UP000076407    UP000075903    UP000075882    UP000076408    UP000078542    UP000075884    UP000076858    UP000075920    UP000000305    UP000283509    UP000030742    UP000094527    UP000001554    UP000261540    UP000001555    UP000018468    UP000018467    UP000261600    UP000007648    UP000261560    UP000261460    UP000265100    UP000265160    UP000240080    UP000005640    UP000265120    UP000264840    UP000265200    UP000261520   

PRIDE

H9JEP3    Q9NRC1   

Pfam

PF04184   ST7

Interpro

IPR007311   ST7        + More
IPR011990   TPR-like_helical_dom_sf       

SUPFAM

SSF48452   SSF48452       

Gene 3D

1.25.40.10    

CDD

cd11557  ST7

ProteinModelPortal

H9JEP3   A0A2H1VXJ1   A0A212F0A0   A0A0P6K139   B0X5U6   A0A182H2N3   + More
A0A0M9A177   A0A0J7P3H8   W5JH00   A0A182FF79   A0A0C9QAR2   E2C7I9   A0A0L7QZS4   A0A3Q1LPG4   E2AM47   A0A1Y1K8J2   A0A146LX50   A0A151WF29   A0A195ATJ9   E9J1K4   F4WKY2   A0A158P3U2   A0A1W4WT20   A0A087ZPH9   A0A2A3EUL2   A0A1Q3F603   A0A336MN84   D6X3H2   A0A154P0B8   A0A026W7Q9   A0A1B0D8Q0   K7J2Z5   A0A232ELU8   A0A1B0CH92   A0A182QKR1   A0A195FJF0   A0A195DZM8   A0A2J7PWR6   A0A067R7W1   A0A182U482   Q7QJH8   A0A182I3E7   A0A182X3M2   A0A182V8I8   A0A182KRF8   A0A182XYZ8   A0A195CNC2   A0A0P4ZEH3   A0A2J7PWR1   A0A182NHR8   A0A164K2P0   A0A182WJ49   A0A0N8A0T2   E9HDV1   A0A0P5TNE7   A0A0P5TK60   A0A2P2I6C2   A0A1B6D6N6   A0A0P6AB91   A0A0P5WUS8   A0A0P5GFE4   A0A1B6M4L4   A0A3R7PEQ7   A0A1B6EYG7   A0A0N7ZJE3   A0A0P4XWZ4   A0A0P5MBD4   A0A0P4W9U9   J3JUX9   A0A1D2MSL3   A0A131Z2E6   L7M774   A0A1E1XDQ3   A0A023GKY1   G3MM84   A0A2R5LKS9   A0A293N6J5   C3YPI6   A0A131XJB9   A0A131Y009   A0A3B3Q998   B7PBY6   A0A0P6I0M7   W5MW97   T1IZ41   W5LB12   A0A3Q3JA04   G3WY21   A0A3B3CDA4   V9KNM4   A0A3B4G615   A0A3P8QKW0   A0A3P9BBA1   A0A2R8ZXV5   Q9NRC1-3   A0A3P8WX59   A0A3Q2VGJ7   A0A3P9HTS5   A0A1A8CUS2   A0A3B4AZN1  

KEGG

101746551    no KO assigned | (RefSeq) protein ST7 homolog

GO

GO:0016021   GO:0030198   GO:0045595  

PANTHER

PTHR12745  

Subcellular location

Membrane  

Length:

459

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

44.48086

Exp number, first 60 AAs:

22.74213

Total prob of N-in:

0.01249

POSSIBLE N-term signal

sequence

outside

1  -  14

TMhelix

15  -  37

inside

38  -  416

TMhelix

417  -  439

outside

440  -  459

 

 

Pi

182.359474

Theta

154.779162

Tajima's D

0.614974

CLR

14.026075

CSRT

0.550822458877056

Interpretation

Uncertain