Gene

KWMTBOMO04956

Pre Gene Modal

BGIBMGA008082

Annotation

hypothetical_protein_KGM_04336_[Danaus_plexippus]

Location

Bomo_Chr9(+):2810820-2826833      View in EpiBrowser

Full name

Proliferating cell nuclear antigen      

Location in the cell

PlasmaMembrane   Reliability : 3.798

CDS

ATGAAGGCCTCCGATACGTTGCACAGAAACGGTAAAAGCGAGAATGGATCCAAAATTACAGAGAAACACGAACAAAAACATAAAGATCCTTTGACGGAAGGCGTGAAATGGATCGAAAGATACGCCGAAAACTTGGAAAATTTCTTCGAGAGACTACCGGAATTCATTTCCACGTTTATAGCGACTCTGGCGGTGTTTACCTTTGGATCAATTTTAAGAGGAGAGTGGGTCGTCATTCTAGTCACAGCGCTGAAGCAAATCACGGGACACACGCAAACCAAAAATGCCTCAGTCGAGGAAATATTCGAGCTGTTCACATCTAGAAACTTGAAAATGGAGAATTTCAGTATCATATTCATATTAGCTAATGTTGTTTCATTTGGATTTTACTTTATCATCGGAGGATTTTTACATTGGTACTTCTACGTGAAGAGAAGGCACCTCGCCAGTGAATGGAAGATCCAGCCGAACAAATGGCTGTCCCCTGAGTTGGAACGCCACGAAATCATGATAGGAACCCTATCTCTCATTATTACAAGTTCATTCTCAGCTTTTTTAGCCTGTTACATCTTCAATGGGAATCCGTGCACAGTCTATTTTCAGTTCGATGAGTACGGATGGATCTGGTTCTTCTTGCAGTTTCCAGTTATTTTCATTTATATTGATTACACGACCTATATTATGCATCGTCTTTATCACACTCCTTGGTTGTACAAGCATTTCCACAAGCTCCACCATAAGTACAAACAGCCTACAGCCTTTTCTGTAACTGCCATCCATCCAGTAGAAATTATGCATATCCAACTAACGATGTGTCTACCTCTCTTCACAATACCTACACATTGGGCATCATTCTACGCTGTGGCCATTTACAATTACTACCACGGCATCATTGATCATTCCGGCATCAATTTTAAGGCCCAGTGGTGGCAGCCGTGGCAGCCTGACGCCGAATTCCATGATCAGCATCACGAATTTTTCCATTGCAACTTTGGCTTCAATATGTATCTGTGGGACAAGTGGCACGGTACGATGAGGAAGCAGTACAACGTGTACACCGAAGAGACATTCCACGGTGAGGCTCCGTCTGCAGAAACGGCCGAAGGAAAGGCGATATTGGAAGCGAACCCCGAACTTATTGATAGTATCAACAAACCATTACTGACAAAGACTGAAACCCAAAAAACTAAATGA

Protein

MKASDTLHRNGKSENGSKITEKHEQKHKDPLTEGVKWIERYAENLENFFERLPEFISTFIATLAVFTFGSILRGEWVVILVTALKQITGHTQTKNASVEEIFELFTSRNLKMENFSIIFILANVVSFGFYFIIGGFLHWYFYVKRRHLASEWKIQPNKWLSPELERHEIMIGTLSLIITSSFSAFLACYIFNGNPCTVYFQFDEYGWIWFFLQFPVIFIYIDYTTYIMHRLYHTPWLYKHFHKLHHKYKQPTAFSVTAIHPVEIMHIQLTMCLPLFTIPTHWASFYAVAIYNYYHGIIDHSGINFKAQWWQPWQPDAEFHDQHHEFFHCNFGFNMYLWDKWHGTMRKQYNVYTEETFHGEAPSAETAEGKAILEANPELIDSINKPLLTKTETQKTK

Description

This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

Similarity

Belongs to the sterol desaturase family.
Belongs to the PCNA family.

Uniprot

H9JEY5   A0A212EYU2   A0A194QD32   A0A2H1X1S0   A0A3S2L4W3   A0A2A4JHB7   + More
A0A194QQX8   A0A0L7LLQ6   D6W8U5   A0A067REM4   A0A1B0D5I1   A0A0T6BHB5   A0A1B6M8U1   V5GYV5   A0A2J7QVD1   J3JUC1   A0A1B0CE06   U4UN31   A0A2P8Y2F5   A0A0P5TR20   A0A0P5TRA2   A0A162NV58   A0A0P5FSY0   A0A0P5E638   A0A0P5CA23   A0A0P5BHW8   A0A0P6H9R4   A0A232EQP5   A0A1D2M1S0   A0A226EP73   E9G489   A0A1W4WN39   A0A1B6HK04   A0A0P6D719   A0A0P6IWD3   A0A0P6BFG3   A0A3R7Q9Z7   A0A0P6FW02   A0A0P5LKG2   A0A0N8D6M9   A0A0P6GFD7   A0A0P5JWC5   A0A0P5KAY6   A0A0N8BIG8   A0A0N8CCW4   A0A0P5P9Z7   A0A0P5YA60   A0A0P5WUF1   A0A0P5NVJ5   A0A0P5S6L9   A0A0N8EEW7   A0A1S3D674   A0A1B6DA27   A0A0P5ACZ6   A0A1S3D6F5   A0A0N8CZZ3   A0A0P5LYT1   A0A1S3JHH3   A0A1S3IIK0   A0A0P5M3B3   A0A0P5U9P3   A7RXC0   A0A2H8TSA6   A0A2S2PA06   A0A087TGT2   A0A087U4C2   J9JVH2   A0A0N8CKJ3   A0A2S2PX93   A0A210Q444   R7UVA9   C3XWE8   F6TVN3   R7TEA4   W4YN73   W4YCZ2  

Pubmed

19121390    22118469    26354079    26227816    18362917    19820115    + More
24845553    22516182    23537049    29403074    28648823    27289101    21292972    17615350    28812685    23254933    18563158    12481130    15114417   

EMBL

BABH01023556    BABH01023557    BABH01023558    BABH01023559    AGBW02011440    OWR46668.1    + More
KQ459185    KPJ03329.1    ODYU01012752    SOQ59217.1    RSAL01000150    RVE45782.1    NWSH01001575    PCG70823.1    KQ461198    KPJ05936.1    JTDY01000669    KOB76279.1    KQ971312    EEZ98257.2    KK852746    KDR17319.1    AJVK01025282    LJIG01000201    KRT86739.1    GEBQ01007713    JAT32264.1    GALX01002833    JAB65633.1    NEVH01010477    PNF32539.1    BT126834    AEE61796.1    AJWK01008460    KB632375    ERL93863.1    PYGN01001017    PSN38445.1    GDIP01122754    JAL80960.1    GDIP01122755    JAL80959.1    LRGB01000531    KZS18293.1    GDIP01144151    JAJ79251.1    GDIP01147554    JAJ75848.1    GDIP01189692    JAJ33710.1    GDIP01189691    JAJ33711.1    GDIQ01044327    JAN50410.1    NNAY01002726    OXU20684.1    LJIJ01006772    ODM86918.1    LNIX01000002    OXA59435.1    GL732531    EFX86052.1    GECU01032698    JAS75008.1    GDIQ01081854    JAN12883.1    GDIQ01003587    JAN91150.1    GDIP01030061    JAM73654.1    QCYY01002156    ROT72445.1    GDIQ01042018    JAN52719.1    GDIQ01170583    JAK81142.1    GDIP01063615    JAM40100.1    GDIQ01044328    JAN50409.1    GDIQ01194260    JAK57465.1    GDIQ01212743    JAK38982.1    GDIQ01174515    JAK77210.1    GDIQ01092147    JAL59579.1    GDIQ01153177    JAK98548.1    GDIP01060659    JAM43056.1    GDIP01093549    JAM10166.1    GDIQ01137097    JAL14629.1    GDIQ01092148    JAL59578.1    GDIQ01033532    JAN61205.1    GEDC01014751    JAS22547.1    GDIP01200743    JAJ22659.1    GDIP01082303    JAM21412.1    GDIQ01172226    JAK79499.1    GDIQ01161372    JAK90353.1    GDIP01117739    JAL85975.1    DS469549    EDO44003.1    GFXV01005044    MBW16849.1    GGMR01013672    MBY26291.1    KK115165    KFM64321.1    KK118087    KFM72211.1    ABLF02027362    GDIP01122703    JAL81011.1    GGMS01000945    MBY70148.1    NEDP02005089    OWF43495.1    AMQN01006015    KB297391    ELU10573.1    GG666471    EEN67682.1    AMQN01013603    KB310334    ELT91807.1    AAGJ04030492    AAGJ04030495   

Proteomes

UP000005204    UP000007151    UP000053268    UP000283053    UP000218220    UP000053240    + More
UP000037510    UP000007266    UP000027135    UP000092462    UP000235965    UP000092461    UP000030742    UP000245037    UP000076858    UP000215335    UP000094527    UP000198287    UP000000305    UP000192223    UP000283509    UP000079169    UP000085678    UP000001593    UP000054359    UP000007819    UP000242188    UP000014760    UP000001554    UP000008144    UP000007110   

PRIDE

H9JEY5    A7RXC0   

Pfam

PF04116   FA_hydroxylase        + More
PF02747   PCNA_C
PF00705   PCNA_N

Interpro

IPR006694   Fatty_acid_hydroxylase        + More
IPR022648   Pr_cel_nuc_antig_N       
IPR022659   Pr_cel_nuc_antig_CS       
IPR000730   Pr_cel_nuc_antig       
IPR022649   Pr_cel_nuc_antig_C       

ProteinModelPortal

H9JEY5   A0A212EYU2   A0A194QD32   A0A2H1X1S0   A0A3S2L4W3   A0A2A4JHB7   + More
A0A194QQX8   A0A0L7LLQ6   D6W8U5   A0A067REM4   A0A1B0D5I1   A0A0T6BHB5   A0A1B6M8U1   V5GYV5   A0A2J7QVD1   J3JUC1   A0A1B0CE06   U4UN31   A0A2P8Y2F5   A0A0P5TR20   A0A0P5TRA2   A0A162NV58   A0A0P5FSY0   A0A0P5E638   A0A0P5CA23   A0A0P5BHW8   A0A0P6H9R4   A0A232EQP5   A0A1D2M1S0   A0A226EP73   E9G489   A0A1W4WN39   A0A1B6HK04   A0A0P6D719   A0A0P6IWD3   A0A0P6BFG3   A0A3R7Q9Z7   A0A0P6FW02   A0A0P5LKG2   A0A0N8D6M9   A0A0P6GFD7   A0A0P5JWC5   A0A0P5KAY6   A0A0N8BIG8   A0A0N8CCW4   A0A0P5P9Z7   A0A0P5YA60   A0A0P5WUF1   A0A0P5NVJ5   A0A0P5S6L9   A0A0N8EEW7   A0A1S3D674   A0A1B6DA27   A0A0P5ACZ6   A0A1S3D6F5   A0A0N8CZZ3   A0A0P5LYT1   A0A1S3JHH3   A0A1S3IIK0   A0A0P5M3B3   A0A0P5U9P3   A7RXC0   A0A2H8TSA6   A0A2S2PA06   A0A087TGT2   A0A087U4C2   J9JVH2   A0A0N8CKJ3   A0A2S2PX93   A0A210Q444   R7UVA9   C3XWE8   F6TVN3   R7TEA4   W4YN73   W4YCZ2  

KEGG

101741096    no KO assigned | (RefSeq) cholesterol 25-hydroxylase-like

GO

GO:0016021   GO:0016491   GO:0005506   GO:0008610   GO:0000254   GO:0005789   GO:0016126   GO:0005634   GO:0030337   GO:0006260   GO:0003677   GO:0006275   GO:0006633   GO:0006508   GO:0015074   GO:0007166   GO:0006032   GO:0005515   GO:0016742   GO:0003824   GO:0055114  

Subcellular location

Nucleus  

Length:

397

Number of predicted TMHs:

5

Exp number of AAs in TMHs:

108.67854

Exp number, first 60 AAs:

3.90205

Total prob of N-in:

0.12783

outside

1  -  54

TMhelix

55  -  77

inside

78  -  114

TMhelix

115  -  137

outside

138  -  169

TMhelix

170  -  192

inside

193  -  204

TMhelix

205  -  227

outside

228  -  263

TMhelix

264  -  286

inside

287  -  397

 

 

Pi

239.374439

Theta

189.077479

Tajima's D

0.491771

CLR

0.613333

CSRT

0.507724613769312

Interpretation

Uncertain