Gene

KWMTBOMO04911  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008013

Annotation

Protein_fat-free-like_protein_[Operophtera_brumata]

Location

Bomo_Chr9(-):1416441-1418669      View in EpiBrowser

Full name

Vacuolar protein sorting-associated protein 51 homolog      

Alternative Name

Protein fat-free homolog

Location in the cell

Nuclear   Reliability : 2.04

CDS

ATGGAGGAAGCCAAAGCGGTTAAAGAAAATCCTCTGGACATCGACAGCAGTAGTTTCAGCCCAGACGTCTACTTAGATTGTCTTCTAAAATGCGCTACCCTAAAGCAAGTAATGGACAAAGAAGCGGAAATTGTAACTCAAAGTCAATTTCTACAATCAGAAATGCAGACATTGGTTTATGAAAATTATAATAAATTTATTTCGGCGACCGAAACTGTACGCAAAATGCGTTCCGATTTTAAAATAATGCAAGAAGAAATGAATAAACTTAGCGAGAATATCAATAAAATAACTACATTCAGCTCTCAAATATCTGAAAATCTCCAAGGCAGCGGTAATAATGTTCGACGTTTGTGTGGTACAAGACAGCTGTTAGATAAACTTCAGTTCCTTTTCCTTCTACCTTCTCAACTTAACAAAGCAATAGCAGAAGGCAGATACAGTGATGCTGTACAAGACTATTCACATGCTCAGCGAGTACTCCAAAAATATGGCAATCAGCCTTCATTCCAAAGCATACAGACTGAGTGTTCAGAAATTATATTTGAACTGAAGAAGACACTCCGTGAAAGACTTATCAGTCCTAATACATCTGCAACTGAACTTGCTGAAAGTGTAGCCCTTTTAAGGCAGCTCCAAGAAAGTGATTCATCCTTACAAGATATATTCCTTAGTTGTGCAGAGAGTCGTCTTGACAAACACTTGCAGATGCTCAGTTCTATAGCTGAACATACAGACATTTTGGACTGGGTAGAAAAATGCAATAATACATTGTTGGCTGATTTAGCTATTATAATATCATGTTACAATGAAATGTTCGAACAGGAAGCTATCATACCCGAATTTGCTGATAAAATAATGATTCAAATTTTTCATTTATTCGAAGAGGTCATTAAAAGACCTGAGAACAACGGAACTGAAATGTTAATAAGGGGCCTTGATAAATTCTTCAGAAAACTCCAGGCTATGACCGAAATATCATCAAGTGATATGATGTCCAGTAAAGGCACTGAGGTTGTCATTCAGTGTATAAATCACAAGGCTATGGTACAGTACCAGAGCATACAGACTCAATTTAAAGACAGTCTTATGAAAGTAAGGCAGTCTTTGGCCAGTAAAGGATCAGAAACAATTGACTTAAAAGATATACTGAACTCCCTTCAAGTATATCTGATGCAAAAAATCCAAGCCTCACTCTTAGATCTAATGGCATTCTTACAAAATAATTTATCATTTGGATTAAAACCTTGGTGTGCAAAAGCAGTAGCTGATGCTTGCTCAAAAGTCATAAATGAAACTATGGCTAATCTTTCTGATCTGGTAAAAAAGATGGCTTGCCTTCAGACTTCAAATAACAACATTCCTTTTGAATTGCTACTTATACTAGCTAAGCTATGTTTGGATATGCAAGAGACTGGTGTCTCGACATTACAGAACCATCTTCTCAAACTCTTAGAAGAGGCTGCTCCTGGCCTCACTGTGGATAACAAGGATACTAGTAGTGTCATGGTCCACTTATCTACTGCAGCGCAGACTGCACTAGATTCAGAAGTTGTATTTATTGGCCAGACTGCAGCCCAAATGTTGAGAGTATCTGTATTAGCTAGAGATTGGTTGCGAGCTCCAGAACCAAGGGGGCCAAGAGCAGTATGCAGAAGAGTAGTGGAGACCTTAGCTAGTGCTGATGGTGCTGCATCTCAACTGTTTCCAACTAGTATTAAACCTTCTAGTGACTCCAGTCGGCGTACTATTTGGTCACGTGCTCCTTCTTCTTTTTCACCTCTTAATAGGATATTCTCTGAAAGAATTGAAGTGTTTAGTCCTGCAGGGGCAGACAGAGCTGCACTATCAAATGGTGCCCTAAAAGTAGCTTTGAAAGCATTAGTTGAATGTGTGCGCCTACGCACATTTGGAAGGCATGGCCTACAGCAATTACAAGTTGATGTTCACTTTCTACAGCAAAGGCTTTCATGTATGGGCAATGATGAGAGGCTTCTAAATGCTTTGCTTGAAGATGCTTTAGCATCAGCACAGTTGAGATGCGTTGACCCACAACTAATGGAACCTAGTATTGTAGATATTATTTGTGAAAGAGGTTGA

Protein

MEEAKAVKENPLDIDSSSFSPDVYLDCLLKCATLKQVMDKEAEIVTQSQFLQSEMQTLVYENYNKFISATETVRKMRSDFKIMQEEMNKLSENINKITTFSSQISENLQGSGNNVRRLCGTRQLLDKLQFLFLLPSQLNKAIAEGRYSDAVQDYSHAQRVLQKYGNQPSFQSIQTECSEIIFELKKTLRERLISPNTSATELAESVALLRQLQESDSSLQDIFLSCAESRLDKHLQMLSSIAEHTDILDWVEKCNNTLLADLAIIISCYNEMFEQEAIIPEFADKIMIQIFHLFEEVIKRPENNGTEMLIRGLDKFFRKLQAMTEISSSDMMSSKGTEVVIQCINHKAMVQYQSIQTQFKDSLMKVRQSLASKGSETIDLKDILNSLQVYLMQKIQASLLDLMAFLQNNLSFGLKPWCAKAVADACSKVINETMANLSDLVKKMACLQTSNNNIPFELLLILAKLCLDMQETGVSTLQNHLLKLLEEAAPGLTVDNKDTSSVMVHLSTAAQTALDSEVVFIGQTAAQMLRVSVLARDWLRAPEPRGPRAVCRRVVETLASADGAASQLFPTSIKPSSDSSRRTIWSRAPSSFSPLNRIFSERIEVFSPAGADRAALSNGALKVALKALVECVRLRTFGRHGLQQLQVDVHFLQQRLSCMGNDERLLNALLEDALASAQLRCVDPQLMEPSIVDIICERG

Description

May act as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.

Subunit

Component of the Golgi-associated retrograde protein (GARP) complex.
Component of the Golgi-associated retrograde protein (GARP) complex Component of the endosome-associated retrograde protein (EARP) complex.

Similarity

Belongs to the VPS51 family.

Keywords

Coiled coil   Complete proteome   Reference proteome   Endosome   Golgi apparatus   Lipid transport   Protein transport   Transport  

Feature

chain  Vacuolar protein sorting-associated protein 51 homolog

Uniprot

H9JER6   A0A0L7LNG8   A0A2H1WXU1   A0A2W1BD04   A0A2A4JNG2   A0A194QK63   + More
A0A194QIT2   A0A1E1W774   B0X770   A0A1Q3F808   A0A0N0BEZ7   A0A067QJH8   A0A088AF26   A0A2A3EV14   A0A2J7RFQ4   A0A232FNE9   A0A195BBN4   K7INY4   A0A151JCS4   A0A195FLH2   Q16KJ4   A0A182HB46   A0A1Y1ND64   A0A151IQH1   E2B9H0   A0A0C9PUE1   A0A3L8DDX5   A0A336LXL0   Q7Q6Z6   B4LJ46   D6X272   A0A182U4T4   A0A1S4FXK0   A0A1S3IN33   A0A182MUN4   A0A182RMJ1   A0A182XN22   B4J7M9   A0A182WKG8   A0A182LJA6   A0A0L7QYD5   A0A1B6MLS5   A0A182VH94   B3MI33   A0A1B6GXN5   A0A0M4EKU1   A0A182HWX9   B4KPL2   A0A1W4UAZ0   A0A1A9UY46   A0A2C9K343   A0A3B0J2W4   B4QD20   Q8MSY4   W8BZL6   B4HP05   A0A1W4UP77   A0A0L0CHZ7   B3NKA2   B4P4A1   A0A1A9Y0G8   Q291X2   B4GA52   A0A1B0B676   A0A0A1XN24   A0A1B0CB26   A0A0K8U7X5   A0A182FEH8   E0VIJ9   W5J5F2   B4MK00   A0A182NHQ4   A0A0K8U6Z8   A0A1J1J2L3   A0A1I8N657   A0A1I8N671   N6TX68   A0A2J7RFP7   A0A026WSA8   A0A1I8N667   A0A2S2NRF4   J9K7Q5   V4CEQ7   A0A0B6ZII1   A0A2H8TG56   A0A1A9ZY13   A0A1I8QD32   Q505L3   A0A1L8GCZ5   R7V5S5   F4WR83   A0A1I8QD70   Q4V9Y0   A0A1L8GJL8   A0A3B0IZ17   A0A3P9LE30   T1J0Z4   A0A1E1XI44  

Pubmed

19121390    26227816    28756777    26354079    24845553    28648823    + More
20075255    17510324    26483478    28004739    20798317    30249741    12364791    17994087    18362917    19820115    20966253    15562597    22936249    10731132    12537572    12537569    24495485    26108605    17550304    15632085    25830018    20566863    20920257    23761445    25315136    23537049    24508170    23254933    27762356    21719571    17554307    28503490   

EMBL

BABH01023425    JTDY01000482    KOB76980.1    ODYU01011873    SOQ57868.1    KZ150199    + More
PZC72291.1    NWSH01000969    PCG73359.1    KQ461198    KPJ05963.1    KQ459185    KPJ03361.1    GDQN01008353    JAT82701.1    DS232440    EDS41764.1    GFDL01011340    JAV23705.1    KQ435821    KOX72348.1    KK853273    KDR09124.1    KZ288185    PBC34911.1    NEVH01004410    PNF39658.1    NNAY01000018    OXU31897.1    KQ976532    KYM81620.1    KQ979048    KYN23217.1    KQ981512    KYN40839.1    CH477954    EAT34821.1    JXUM01031693    KQ560932    KXJ80293.1    GEZM01006009    JAV95833.1    KQ976780    KYN08398.1    GL446527    EFN87653.1    GBYB01004988    JAG74755.1    QOIP01000009    RLU18531.1    UFQS01000205    UFQT01000205    SSX01331.1    SSX21711.1    AAAB01008960    EAA11747.3    CH940648    EDW61482.2    KQ971371    EFA10222.1    AXCM01016594    CH916367    EDW02177.1    KQ414688    KOC63630.1    GEBQ01003125    JAT36852.1    CH902619    EDV38043.1    GECZ01002590    JAS67179.1    CP012524    ALC42067.1    APCN01001587    CH933808    EDW09122.1    OUUW01000001    SPP73503.1    CM000362    CM002911    EDX07725.1    KMY94924.1    AE013599    AY118494    GAMC01007794    JAB98761.1    CH480816    EDW48507.1    JRES01000378    KNC31837.1    CH954179    EDV55124.1    CM000158    EDW91587.1    CM000071    EAL24990.1    CH479181    EDW31804.1    JXJN01009007    GBXI01002022    JAD12270.1    AJWK01004777    GDHF01029633    JAI22681.1    DS235200    EEB13205.1    ADMH02002097    ETN59216.1    CH963846    EDW72439.1    GDHF01029961    JAI22353.1    CVRI01000064    CRL05073.1    APGK01057453    KB741280    KB632033    ENN70912.1    ERL88212.1    PNF39659.1    KK107119    EZA58546.1    GGMR01007151    MBY19770.1    ABLF02022130    KB200702    ESP00450.1    HACG01021544    CEK68409.1    GFXV01001259    MBW13064.1    BC094495    CM004473    OCT81748.1    AMQN01004913    KB294684    ELU14198.1    GL888284    EGI63300.1    BC096636    CM004472    OCT84019.1    SPP73504.1    JH431742    GFAC01000432    JAT98756.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053240    UP000053268    UP000002320    + More
UP000053105    UP000027135    UP000005203    UP000242457    UP000235965    UP000215335    UP000078540    UP000002358    UP000078492    UP000078541    UP000008820    UP000069940    UP000249989    UP000078542    UP000008237    UP000279307    UP000007062    UP000008792    UP000007266    UP000075902    UP000085678    UP000075883    UP000075900    UP000076407    UP000001070    UP000075920    UP000075882    UP000053825    UP000075903    UP000007801    UP000092553    UP000075840    UP000009192    UP000192221    UP000078200    UP000076420    UP000268350    UP000000304    UP000000803    UP000001292    UP000037069    UP000008711    UP000002282    UP000092443    UP000001819    UP000008744    UP000092460    UP000092461    UP000069272    UP000009046    UP000000673    UP000007798    UP000075884    UP000183832    UP000095301    UP000019118    UP000030742    UP000053097    UP000007819    UP000030746    UP000092445    UP000095300    UP000186698    UP000014760    UP000007755    UP000008143    UP000265180   

PRIDE

H9JER6    Q8MSY4    Q505L3    Q4V9Y0   

Pfam

PF15469   Sec5

Interpro

IPR014812   Vps51        + More
IPR016159   Cullin_repeat-like_dom_sf       
IPR039481   EXOC2/Sec5_N_dom       

SUPFAM

SSF74788   SSF74788       

ProteinModelPortal

H9JER6   A0A0L7LNG8   A0A2H1WXU1   A0A2W1BD04   A0A2A4JNG2   A0A194QK63   + More
A0A194QIT2   A0A1E1W774   B0X770   A0A1Q3F808   A0A0N0BEZ7   A0A067QJH8   A0A088AF26   A0A2A3EV14   A0A2J7RFQ4   A0A232FNE9   A0A195BBN4   K7INY4   A0A151JCS4   A0A195FLH2   Q16KJ4   A0A182HB46   A0A1Y1ND64   A0A151IQH1   E2B9H0   A0A0C9PUE1   A0A3L8DDX5   A0A336LXL0   Q7Q6Z6   B4LJ46   D6X272   A0A182U4T4   A0A1S4FXK0   A0A1S3IN33   A0A182MUN4   A0A182RMJ1   A0A182XN22   B4J7M9   A0A182WKG8   A0A182LJA6   A0A0L7QYD5   A0A1B6MLS5   A0A182VH94   B3MI33   A0A1B6GXN5   A0A0M4EKU1   A0A182HWX9   B4KPL2   A0A1W4UAZ0   A0A1A9UY46   A0A2C9K343   A0A3B0J2W4   B4QD20   Q8MSY4   W8BZL6   B4HP05   A0A1W4UP77   A0A0L0CHZ7   B3NKA2   B4P4A1   A0A1A9Y0G8   Q291X2   B4GA52   A0A1B0B676   A0A0A1XN24   A0A1B0CB26   A0A0K8U7X5   A0A182FEH8   E0VIJ9   W5J5F2   B4MK00   A0A182NHQ4   A0A0K8U6Z8   A0A1J1J2L3   A0A1I8N657   A0A1I8N671   N6TX68   A0A2J7RFP7   A0A026WSA8   A0A1I8N667   A0A2S2NRF4   J9K7Q5   V4CEQ7   A0A0B6ZII1   A0A2H8TG56   A0A1A9ZY13   A0A1I8QD32   Q505L3   A0A1L8GCZ5   R7V5S5   F4WR83   A0A1I8QD70   Q4V9Y0   A0A1L8GJL8   A0A3B0IZ17   A0A3P9LE30   T1J0Z4   A0A1E1XI44  

KEGG

101737710    K20296 vacuolar protein sorting-associated protein 51 | (RefSeq) vacuolar protein sorting-associated

GO

GO:0005802   GO:0016020   GO:0007030   GO:0042147   GO:0005829   GO:0032456   GO:0007041   GO:0048193   GO:1990745   GO:0000938   GO:0006869   GO:0055037   GO:0015031  

PANTHER

PTHR15954  

Subcellular location

Golgi apparatus   Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.   With evidence from 1 publications.
trans-Golgi network   Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.   With evidence from 1 publications.
Recycling endosome   Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.   With evidence from 1 publications.

Length:

699

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0014

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00055

outside

1  -  699

 

 

Pi

179.614427

Theta

222.982477

Tajima's D

-0.669202

CLR

308.500039

CSRT

0.202089895505225

Interpretation

Uncertain