Gene

KWMTBOMO04898

Pre Gene Modal

BGIBMGA008018

Annotation

membrane_alanyl_aminopeptidase-like_[Bombyx_mori]

Location

Bomo_Chr9(-):1082850-1088824      View in EpiBrowser

Full name

Aminopeptidase       + More
Membrane alanyl aminopeptidase      

Alternative Name

Aminopeptidase N-like protein
BTBP1
CryIA(C) receptor

Location in the cell

Cytoplasmic   Reliability : 2.383

CDS

ATGCTTCATGATGCTTACGTTAATGCAAATCCCTTAGAACCCAAAGAAGAGCTCTATGATGAAGATGAAATTAGGAGTAACATATACGGGCTTTCTAAACTAAAAGCTCCCGCTATTCTGCATATGTTGAAATTAGTGCTTGGTGATGAAGGTCAAGACTTCGTTCATTCTGCCGCCAAGAATCTGCTTCGAAGAAGGTCGGTGGAGACGGTGAACACACATAATTTGATCGGCGCCATTATCGATGACTGGTCAATCAATGGCAACGAAATGATTGATGATATAGAGTCGTTCTTAGAACCTTGGATCGAAAACAATGGTTATCCAATGATACACGTTGGACTGAGACAAGACGGTTCTGTTTTCATAATGCAGGAGAGGTTTAGCTTCACACCTCAAGCACACGTCAACTACGAAATCCCCATCACATATACGACGAAGGCCAGCCCCAACTTCAACAATATTCGACCGATACTCATGATGGATGCGACTACAAACCTCAACGTTCGTCTCACCGGAGACGAATGGGTGCTTTTCAATATACAGGGACAAAGCTACTACCGAGTCAACTATGATGATGATATTTGGGATCGGATTCTTGAAGCCCTCGAGGACCCTGAGGATAGAAAAGTGATCCATCCATTGAACCGCGCCAAGCTCGTAGATGATGCATTGAATTTGGCAAGATCTGGAAAATTGGATTATGAGATAGCATTCAAGGTAGTTCTATCTATGGAGCACGAAACCGAGTACGCTGTATGGAAAGCCTTCGTCAGGAATATGGACTTCTTGAGAAAACGCCTAATTGCTCACGTCACAGAAGACGACGATTTGGATCCTGATATTTATATGGTGCGTGGGTACATCAGTATCAATGAGCTTTAG

Protein

MLHDAYVNANPLEPKEELYDEDEIRSNIYGLSKLKAPAILHMLKLVLGDEGQDFVHSAAKNLLRRRSVETVNTHNLIGAIIDDWSINGNEMIDDIESFLEPWIENNGYPMIHVGLRQDGSVFIMQERFSFTPQAHVNYEIPITYTTKASPNFNNIRPILMMDATTNLNVRLTGDEWVLFNIQGQSYYRVNYDDDIWDRILEALEDPEDRKVIHPLNRAKLVDDALNLARSGKLDYEIAFKVVLSMEHETEYAVWKAFVRNMDFLRKRLIAHVTEDDDLDPDIYMVRGYISINEL

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M1 family.
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.

Keywords

Aminopeptidase   Cell membrane   Direct protein sequencing   Glycoprotein   GPI-anchor   Hydrolase   Lipoprotein   Membrane   Metal-binding   Metalloprotease   Protease   Signal   Zinc  

Feature

chain  Aminopeptidase
propeptide  Activation peptide

Uniprot

H9JES1   I3VR82   A0A194QR13   A0A286LQ00   A0A194QD33   A0A2A4J290   + More
A0A2H1VVS9   A0A2W1BM20   A0A2H1VG23   A0A2A4IVH9   A0A212EJS2   A0A0L7LHA5   A0A076VDI4   A4D0J5   H9JEW5   I3VR73   A0A195BIR1   G3ESW0   A0A2W1BU00   K9MBJ8   A7YAH7   M4M1W4   A0A3S2M847   A0A195DN37   A0A158P3F3   H9JEW4   I3VR74   Q8MU78   Q8ITD3   A1E3B6   S4VAT7   A0A212EJS3   A0A195EZF3   Q7Z267   G3ESV9   Q95UF9   D2KHN4   A0A2A4IXQ9   E8Z9T8   Q7Z266   K7J1L8   A0A195BIK5   A0A195CCY0   Q9NHZ7   H9JEW2   D2KHN5   A0A2J7RAG9   A0A2J7RAH0   Q9GT75   G3ESV8   A0A195DN33   A5JJU1   A0A195F0B1   O16851   G3ESV2   D9HP35   A0A2H1WZJ8   Q11000   A4D0J3   E9JC19   A0A232FGY1   O76803   A0A2Z3YKX3   A0A151WZ01   Q19TV9   V5NQ96   V5NPR9   A0A0L7LCB7   O17484   O17485   A0A3L8E4L7   A0A026W0P7   Q9XYV2   A0A1J1HMY9   A0A286LPZ6   A0A154PML5   E8Z5S9   A0A0L7QWL2   A0A024AX72   D5G3H6   A0A2A4IYF9   Q7Z0W1   A0A194QKB6   A0A2W1BR73   Q9U8B0   Q962B3   S4VDN0   E0A211   G9C5G2   G0ZL61   A0A336M794   E9JC17   A0A2H1WAG0   A0A336KP62   A0A336KRZ8   A0A336MBJ6   A0A212EJS8  

EC Number

3.4.11.-

Pubmed

19121390    26354079    28756777    22118469    26227816    24932922    + More
15857766    24121099    21347285    12441000    20420910    20075255    11439249    10989294    10380100    21205278    7592988    21282665    28648823    9931470    17402938    24045122    10732989    30249741    24508170    10406091    20005949    10366728    12023048    20685334    21840855    21844358   

EMBL

BABH01023395    BABH01023396    BABH01023397    BABH01023398    JQ061153    AFK85027.1    + More
KQ461198    KPJ05971.1    MF425657    ASU92549.1    KQ459185    KPJ03372.1    NWSH01003448    PCG66277.1    ODYU01004747    SOQ44951.1    KZ149969    PZC76122.1    ODYU01002173    SOQ39332.1    NWSH01006029    PCG63731.1    AGBW02014405    OWR41739.1    JTDY01001142    KOB74749.1    KF900124    AIK27005.1    AY836581    AAX39865.1    BABH01023392    JQ061144    AFK85018.1    KQ976467    KYM84198.1    JF339040    AEO12697.1    PZC76116.1    JQ088280    AFU51580.1    EU137839    ABV01346.1    JQ747495    AGG36452.1    RSAL01000014    RVE53193.1    KQ980713    KYN14241.1    ADTU01007781    ADTU01007782    ADTU01007783    BABH01023391    JQ061145    AFK85019.1    AF535166    AAN04900.1    AF521660    AAN75694.1    EF103944    ABL01483.1    KC776602    AGO57906.1    OWR41737.1    KQ981905    KYN33598.1    AY279536    AAP37952.1    AEO12696.1    AY052651    AAL14117.2    GU213039    ADA59491.1    NWSH01005016    PCG64491.1    FJ896130    ADA57169.1    AY279537    AAP37953.1    KYM84197.1    KQ977935    KYM98719.1    AF217250    AAF37560.1    BABH01023388    BABH01023389    BABH01023390    GU213040    ADA59492.1    NEVH01006570    PNF37826.1    PNF37825.1    AF276241    AAF99701.1    AEO12695.1    KYN14242.1    EF538427    ABQ51393.1    KYN33597.1    AF020389    AAB70755.1    JF339038    AEO12689.1    HM012709    ADI48183.1    ODYU01012236    SOQ58437.1    U35096    AY836579    AAX39863.1    GL771642    EFZ09647.1    NNAY01000207    OXU30026.1    AF084257    JQ061146    AAC33301.1    AFK85020.1    KY949255    AWT22997.1    KQ982649    KYQ53113.1    DQ444715    ABE02186.1    KF537664    AHA90591.1    KF537663    AHA90590.1    JTDY01001695    KOB73138.1    AF034483    AAC36148.1    AF034484    AAC36147.1    QOIP01000001    RLU27566.1    KK107589    EZA48634.1    AF126442    AAD31183.1    CVRI01000004    CRK87601.1    MF425653    ASU92545.1    KQ434984    KZC13131.1    FJ492806    ACT35083.1    KQ414710    KOC62990.1    KJ143755    AHZ08543.1    FJ997340    ADF43505.1    NWSH01005085    PCG64448.1    AY279535    AY346383    AAP37951.1    AAQ24379.1    KPJ05977.1    PZC76115.1    AF109692    AAF01259.2    AY038608    AAK85539.1    KC776603    AGO57907.1    HM231318    ADL38970.1    HQ853294    ADZ05466.1    JF303657    AEA29693.1    UFQS01000655    UFQT01000655    SSX05825.1    SSX26184.1    EFZ09701.1    ODYU01007373    SOQ50075.1    SSX05822.1    SSX26181.1    SSX05823.1    SSX26182.1    SSX05824.1    SSX26183.1    OWR41736.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000218220    UP000007151    UP000037510    + More
UP000078540    UP000283053    UP000078492    UP000005205    UP000078541    UP000002358    UP000078542    UP000235965    UP000215335    UP000075809    UP000279307    UP000053097    UP000183832    UP000076502    UP000053825   

PRIDE

H9JES1    I3VR82    H9JEW5    I3VR73    H9JEW4    I3VR74    + More
E8Z9T8    H9JEW2    Q11000    O76803    E8Z5S9    Q9U8B0   

Pfam

PF11838   ERAP1_C        + More
PF01433   Peptidase_M1
PF00858   ASC

Interpro

IPR014782   Peptidase_M1_dom        + More
IPR024571   ERAP1-like_C_dom       
IPR042097   Aminopeptidase_N-like_N       
IPR001930   Peptidase_M1       
IPR034016   M1_APN-typ       
IPR033581   APN2       
IPR020903   ENaC_CS       
IPR001873   ENaC       

Gene 3D

2.60.40.1730    

CDD

cd09601  M1_APN_2

ProteinModelPortal

H9JES1   I3VR82   A0A194QR13   A0A286LQ00   A0A194QD33   A0A2A4J290   + More
A0A2H1VVS9   A0A2W1BM20   A0A2H1VG23   A0A2A4IVH9   A0A212EJS2   A0A0L7LHA5   A0A076VDI4   A4D0J5   H9JEW5   I3VR73   A0A195BIR1   G3ESW0   A0A2W1BU00   K9MBJ8   A7YAH7   M4M1W4   A0A3S2M847   A0A195DN37   A0A158P3F3   H9JEW4   I3VR74   Q8MU78   Q8ITD3   A1E3B6   S4VAT7   A0A212EJS3   A0A195EZF3   Q7Z267   G3ESV9   Q95UF9   D2KHN4   A0A2A4IXQ9   E8Z9T8   Q7Z266   K7J1L8   A0A195BIK5   A0A195CCY0   Q9NHZ7   H9JEW2   D2KHN5   A0A2J7RAG9   A0A2J7RAH0   Q9GT75   G3ESV8   A0A195DN33   A5JJU1   A0A195F0B1   O16851   G3ESV2   D9HP35   A0A2H1WZJ8   Q11000   A4D0J3   E9JC19   A0A232FGY1   O76803   A0A2Z3YKX3   A0A151WZ01   Q19TV9   V5NQ96   V5NPR9   A0A0L7LCB7   O17484   O17485   A0A3L8E4L7   A0A026W0P7   Q9XYV2   A0A1J1HMY9   A0A286LPZ6   A0A154PML5   E8Z5S9   A0A0L7QWL2   A0A024AX72   D5G3H6   A0A2A4IYF9   Q7Z0W1   A0A194QKB6   A0A2W1BR73   Q9U8B0   Q962B3   S4VDN0   E0A211   G9C5G2   G0ZL61   A0A336M794   E9JC17   A0A2H1WAG0   A0A336KP62   A0A336KRZ8   A0A336MBJ6   A0A212EJS8  

PDB

4WZ9     E-value=2.70723e-25,     Score=285

KEGG

101737010    K11140 aminopeptidase N [EC:3.4.11.2] | (RefSeq) membrane alanyl aminopeptidase-like

GO

GO:0016021   GO:0008237   GO:0008270   GO:0004177   GO:0006508   GO:0031225   GO:0005886   GO:0005272  

PANTHER

PTHR11533:SF246  

Subcellular location

Cell membrane  

Length:

294

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00141

Exp number, first 60 AAs:

0.000610000000000001

Total prob of N-in:

0.04461

outside

1  -  294

 

 

Pi

283.237295

Theta

165.66646

Tajima's D

0.433801

CLR

0.055419

CSRT

0.498875056247188

Interpretation

Uncertain