Gene

KWMTBOMO04895  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008018

Annotation

membrane_alanyl_aminopeptidase-like_[Bombyx_mori]

Location

Bomo_Chr9(-):1071331-1077154      View in EpiBrowser

Full name

Aminopeptidase      

CDS

ATGGTGCGTAGAACTGTGGGTGCACTTGAAGACGAAATTGGATTCAATCCTGATACATCACTCACTGAGCCTGCAATGGTTTCCTTGACCAGAGGTCTGGTAATGGATCACGCCTGCAGGGCCAATTATGAGCCATGCATTGCAGCCGCTATCGATTTGTTCTATAATCCCAATAACAATGAAGAAGTAAATCCCAACATCCCATCTGATATCAGACCAGCGGTCTACTGTACCATGGTAAGAGAAGGAGATGAGGACGTGATAGAAGCATTGAAAGCTAGATTGGAAGTTGAGGCAAACCATTACGAGCGAGTTGTCATATTAGAGTCGTTGGCCTGCTCAGATGATCAAAACTTTATACGAAATTACCTTGAAGAAACGATAGCTGCAGGTAATGAATACGGTGTGGAAGAAAGAGTCAGGATATTTAGAGCAGTAGCTGAAAGTAGTTACGAGAATGCGAGAGTGGCTTTAAGCTTTATTTCAATGCGCACTAATGAGATAAGAGATAATTATGGCGGCCCGAAAAAATTAGAAGAGATACTTTTCGTATTGGGTGAAAACATGGCGAATGATATATTATCTGAAGACTTCCGGATTTGGGTGAGATCGCAGTCAAATGATTTGGATGATTCTCAAGGAGCTGCAAACAGGGCATTGGCGATTGTTCTTGAGAATGTCAACTGGATTGAGCGCCACCAAGATTATGTCTACGATTGGATAGACGAGAACGACGCACCAACTTTAGCTGCATCATTAATTCTAATTTGTATAACAATCTTTGTTACTCTATTTAATAATTAG

Protein

MVRRTVGALEDEIGFNPDTSLTEPAMVSLTRGLVMDHACRANYEPCIAAAIDLFYNPNNNEEVNPNIPSDIRPAVYCTMVREGDEDVIEALKARLEVEANHYERVVILESLACSDDQNFIRNYLEETIAAGNEYGVEERVRIFRAVAESSYENARVALSFISMRTNEIRDNYGGPKKLEEILFVLGENMANDILSEDFRIWVRSQSNDLDDSQGAANRALAIVLENVNWIERHQDYVYDWIDENDAPTLAASLILICITIFVTLFNN

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M1 family.

Feature

chain  Aminopeptidase

Uniprot

I3VR82   H9JES1   A0A194QR13   A0A194QD33   A0A286LQ00   A0A2H1VG23   + More
A0A2W1BM20   A0A0L7LHA5   A0A2H1VVS9   A0A2A4IVH9   A0A2A4J290   A0A212EJS2   Q8MUT5   Q7Z268   Q8MU79   A0A2W1BSE9   Q9NHZ8   Q86QI6   C9W8K9   Q963G0   Q0PDN2   A0A0L7L425   F2YWM1   G9C5G4   A0A2J7RAG9   A0A2J7RAH0   A0A182XHW8   A0A087ZUB2   A0A1L8E2T9   A4D0J6   A0A2H1WAU1   A0A067RF43   Q95WL1   A0A1B0CGE2   A0A182HSV0   Q7QC91   A0A2A4J832   Q964F9   A0A182PUT5   A0A212EJS8   A0A310SKF7   A0A2P8Y405   Q9XYV3   G9C5G3   A0A2J7RAG5   A0A0C9R4H9   A0A0N0BIW4   A0A0T6B4M8   A0A1W5BDR3   A0A1W5BEF8   F6X9G8   B3P5I5   Q4G6A2   T1P9B0   A0A0C9RIL7   A0A076YIK8   A0A194QD38   A0A1I8N5N4   U5EWR8   A0A087SVG3   A0A154PML5   Q6PWP5   F4W4E4   A0A212EJU3   O46156   A0A158P3F5   Q6J4J3   G3ESV7   D3YJ03   A0A0C9RIM2   S4VDN0   A0A026VYW9   A0A0C9QEZ7   K7J1L8   A0A3L8E5F4   D2KHN2   A0A194QR18   A0A194QK79   A0A232FGY1   A0A2R7VTS0   O77046   A0A1Q3FS18   D2KHN1   D3YJ04   A0A2Z3YIN5   A0A087ZUB4   A0A1W4VR30   B2LS41   Q8T5Q4   G9C7N4   Q6Q2I1   A0A1I9WL50   A0A2L1IQ82   A0A182W7Y5   Q9VAM2   A0A1S5QN38   A0A2A3ELA7  

EC Number

3.4.11.-

Pubmed

19121390    26354079    28756777    26227816    22118469    11439249    + More
20824821    17402938    15857766    24845553    12364791    14747013    17210077    12200317    29403074    10406091    12481130    15114417    17994087    15978131    25315136    21719571    21347285    24121099    24508170    20075255    30249741    28648823    27538518    29415259    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867   

EMBL

JQ061153    AFK85027.1    BABH01023395    BABH01023396    BABH01023397    BABH01023398    + More
KQ461198    KPJ05971.1    KQ459185    KPJ03372.1    MF425657    ASU92549.1    ODYU01002173    SOQ39332.1    KZ149969    PZC76122.1    JTDY01001142    KOB74749.1    ODYU01004747    SOQ44951.1    NWSH01006029    PCG63731.1    NWSH01003448    PCG66277.1    AGBW02014405    OWR41739.1    AF511038    AAM44056.1    AY279534    AAP37950.1    AF535165    AAN04899.1    PZC76117.1    AF217249    AAF37559.1    AY181026    AAO23562.1    FJ210822    ACN69219.1    AF378666    AAK58066.1    DQ872666    ABH07377.2    JTDY01003068    KOB70212.1    JF509138    ADZ74247.1    HQ853296    ADZ05468.1    NEVH01006570    PNF37826.1    PNF37825.1    GFDF01001118    JAV12966.1    AY836582    AAX39866.1    ODYU01007373    SOQ50076.1    KK852505    KDR22501.1    AF317619    AAL26894.1    AJWK01011046    AJWK01011047    APCN01000366    AAAB01008859    EAA08230.5    NWSH01002538    PCG68029.1    AF320764    AAK69605.1    OWR41736.1    KQ760397    OAD60664.1    PYGN01000952    PSN39002.1    AF126443    AAD31184.1    HQ853295    ADZ05467.1    PNF37829.1    GBYB01002810    GBYB01007837    JAG72577.1    JAG77604.1    KQ435724    KOX78331.1    LJIG01009863    KRT82230.1    EAAA01002576    CH954182    EDV53235.1    AY218845    AAP44967.1    KA644745    AFP59374.1    GBYB01013077    JAG82844.1    KM034756    AIK67332.1    KPJ03377.1    GANO01001287    JAB58584.1    KK112145    KFM56852.1    KQ434984    KZC13131.1    AY573579    AAS82738.1    GL887532    EGI70839.1    OWR41740.1    AJ222699    CAA10950.1    ADTU01007783    ADTU01007784    ADTU01007785    AY601813    AAT45356.1    JF339039    AEO12694.1    GU479676    ADD39717.1    GBYB01013082    JAG82849.1    KC776603    AGO57907.1    KK107589    EZA48631.1    GBYB01013078    GBYB01013080    JAG82845.1    JAG82847.1    QOIP01000001    RLU27565.1    GU213037    ADA59489.1    KPJ05976.1    KPJ05978.1    NNAY01000207    OXU30026.1    KK854013    PTY09335.1    AB013400    BAA33715.1    GFDL01004812    JAV30233.1    GU213036    ADA59488.1    GU479677    ADD39718.1    KY949254    AWT22996.1    EU571948    ACB87202.2    AF498996    AAM18718.1    HQ901596    ADZ57273.1    AY564236    AAS75551.1    KU932234    APA33870.1    MF741655    AVD96938.1    AE014297    AAF56882.2    KR068519    AMO02536.1    KZ288223    PBC31976.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000037510    UP000218220    UP000007151    + More
UP000235965    UP000076407    UP000005203    UP000027135    UP000092461    UP000075840    UP000007062    UP000075885    UP000245037    UP000053105    UP000008144    UP000008711    UP000095301    UP000054359    UP000076502    UP000007755    UP000005205    UP000053097    UP000002358    UP000279307    UP000215335    UP000192221    UP000075920    UP000000803    UP000242457   

PRIDE

I3VR82    H9JES1    O77046    Q9VAM2   

Pfam

PF01433   Peptidase_M1        + More
PF11838   ERAP1_C

Interpro

IPR042097   Aminopeptidase_N-like_N        + More
IPR024571   ERAP1-like_C_dom       
IPR014782   Peptidase_M1_dom       
IPR001930   Peptidase_M1       
IPR034016   M1_APN-typ       
IPR033581   APN2       
IPR008936   Rho_GTPase_activation_prot       

SUPFAM

SSF48350   SSF48350       

Gene 3D

2.60.40.1730    

CDD

cd09601  M1_APN_2

ProteinModelPortal

I3VR82   H9JES1   A0A194QR13   A0A194QD33   A0A286LQ00   A0A2H1VG23   + More
A0A2W1BM20   A0A0L7LHA5   A0A2H1VVS9   A0A2A4IVH9   A0A2A4J290   A0A212EJS2   Q8MUT5   Q7Z268   Q8MU79   A0A2W1BSE9   Q9NHZ8   Q86QI6   C9W8K9   Q963G0   Q0PDN2   A0A0L7L425   F2YWM1   G9C5G4   A0A2J7RAG9   A0A2J7RAH0   A0A182XHW8   A0A087ZUB2   A0A1L8E2T9   A4D0J6   A0A2H1WAU1   A0A067RF43   Q95WL1   A0A1B0CGE2   A0A182HSV0   Q7QC91   A0A2A4J832   Q964F9   A0A182PUT5   A0A212EJS8   A0A310SKF7   A0A2P8Y405   Q9XYV3   G9C5G3   A0A2J7RAG5   A0A0C9R4H9   A0A0N0BIW4   A0A0T6B4M8   A0A1W5BDR3   A0A1W5BEF8   F6X9G8   B3P5I5   Q4G6A2   T1P9B0   A0A0C9RIL7   A0A076YIK8   A0A194QD38   A0A1I8N5N4   U5EWR8   A0A087SVG3   A0A154PML5   Q6PWP5   F4W4E4   A0A212EJU3   O46156   A0A158P3F5   Q6J4J3   G3ESV7   D3YJ03   A0A0C9RIM2   S4VDN0   A0A026VYW9   A0A0C9QEZ7   K7J1L8   A0A3L8E5F4   D2KHN2   A0A194QR18   A0A194QK79   A0A232FGY1   A0A2R7VTS0   O77046   A0A1Q3FS18   D2KHN1   D3YJ04   A0A2Z3YIN5   A0A087ZUB4   A0A1W4VR30   B2LS41   Q8T5Q4   G9C7N4   Q6Q2I1   A0A1I9WL50   A0A2L1IQ82   A0A182W7Y5   Q9VAM2   A0A1S5QN38   A0A2A3ELA7  

PDB

4WZ9     E-value=5.81276e-05,     Score=109

KEGG

101737010    K11140 aminopeptidase N [EC:3.4.11.2] | (RefSeq) membrane alanyl aminopeptidase-like

GO

GO:0008270   GO:0004177   GO:0008237   GO:0016021   GO:0006508   GO:0007165   GO:0005737   GO:0070006   GO:0043171   GO:0042277  

PANTHER

PTHR11533:SF246  

Length:

267

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

16.3911

Exp number, first 60 AAs:

0.00146

Total prob of N-in:

0.25683

outside

1  -  245

TMhelix

246  -  265

inside

266  -  267

 

 

Pi

160.451739

Theta

156.5994

Tajima's D

-0.335949

CLR

1.006651

CSRT

0.28163591820409

Interpretation

Uncertain