SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO04885
Pre Gene Modal
BGIBMGA008058
Annotation
protease_m1_zinc_metalloprotease_[Danaus_plexippus]
Full name
Aminopeptidase      
Location in the cell
PlasmaMembrane   Reliability : 1.496
 

Sequence

CDS
ATGCAAACACATGAACCATTAAACGTAGTGGATGGCACTACGAAAACCGAAAGAGGAATCATTCTATCAAAGCCGTTAGTTCTATTTATATTCGTAATATTCGTACTGACTTTGGTGACGTCATCGCTTTTGGTGTACAATTTCGCTGCCTGCCCTAAAACTGATCAGCTGGCTAATGTCACAAAATACGAACTCTGTAGAGTTGCGGAAGCTAAACTGTCCCTTAATGAAACTAATAAAGATATACCTAAAGACAGGAATATAGAGGCTAACGATAAGAAATCAGCAACAGAAAGAAATATAGCTATAAGTAAGAATGAAATAGAGAAAGTCAAAGATGCAGAAGGTAAAGACGTCATGAACGATACAAATTTGGAGACACCTAAAGAATTTCGTTTACCTCAAAACGTGAAGCCGGAGAATTATTATCTAAACATTACTCCATTCTTCTTAGAGAATAATTTCACGTTTCAAGGCGAAGTTACTATATTGTTAACGGTTTTTAATGAGACTAATGAGATTATCTTCCATGGAGTCGATTTAGTGTTTAGAGATCTGAAGTTGCTGACAGAGAAAGATAGAAGAATAATAGACATCCTGAAAACAGAGGAAGATAAATTGAGGCAGTTTCATACAGTGACCGTTCGAGATAAATTAGAGGTTGGAATGCAGTATCTATTGGTAATAAGCTACTCAGGGGTCCTTAACGATGATCTCCATGGTTTTTATAGGAGCTCTTATGAAGACGGAGGCGTTAGAAAGTGGATAGCTGTGACGCAGTTCCAAGCTATGGACGCCCGGAGAGCGTTCCCTTGCTGGGACGAGCCGGCCATGAAGGCGCGGTTCACTATTACCATCGGAAGACCGGCCAATATGACTTCCTTGTCCAATATGAACAGTATTAAGCAGTCCCCACATGACAGTGTCGAAGGCTACATTAATGATTTTTACGAAGAATCATTGCCGATGTCGACGTATCTCGTCGCGTTTGCCGTCACAGATTTCAGTAGTAAATCGAAGGACACGTTCTCGGTGTGGGCGCGACATAAAGTCCTACCGGCCGCTTCTTTCGCCCTCGAAATCGGCTCGAAGATACTGAAGTTTCTAGAGAATTATTACGATATAAAATTTCCTTTACCGAAGATCGACATGATTGCTTTACCGGACTTCAAGAACGGTGCTATGGAGAACTGGGGACTCTTGACTTTCAGGGAAATAGCCATGCTTTACCAGCAAGGTGTGTCAGCTACGATGGACAAGGTGCACGTGGCCACCGTGGTCGCTCACGAGATCGCTCATCAGTGGTTCGGGAACCTCGTGACGCCTTCCTGGTGGCGAGACCTTTGGCTGAACGAGGGTTTCGCTACGTACGTCGAATACGTTGCTGTCGATGCTGTTGAGAAATCGTGGAATCTTACCGAGCTGTGTATTTTGGACCAAGTCCACAATGTATTCCAATTGGATGCGCTGAACTCTTCGCATCAGCTCTCCGTCGACGTCACGGCTTCCGAAGAGACCGACGCTATATTTGACAAAATATCATATGGAAAAGGTGCCGCTCTGCTCCGGATGCTGAACCACATTCTCACTGATGATATCTTCAACGCGGGCGTCACTAACTACCTGAAATCGAAGATGTATGGGAACGCGGAGCAGAAGGATCTCTGGGCTGCGCTGACTGCGGTCGCCACGCAAAGGAACCTCAAAATCGATGTTGCGGTCGTCATGGACTCGTGGACTTTGCAGACTGGATTCCCGGTGCTCACCGTCAATAGAGATTACGGAAACCAACAAATCAAATTCAGTCAGGAAAGGTTCGTACTGATCAATGAAACATCATCATCTCAACAAGCGCCCCTGTGGTGGATACCTGTGTCTTACACAACAGCTTCCGAGCAAGATTTCCGGTCGACCAGACCAAAGTTCTGGCTTGAGGGAGTGCAGAGTGTCGTCAAAGACTTCCCTGTCAAGAACGAGGACTGGTTAATTGTTAATATTCAAGAAACAGGTTTCTACCGCGTGAACTACGACACCCGTAACTGGCAACTCCTGACTGCGGTACTCAACGACAAGAATCGTTTTCAAGAAATCCACGTCATCAATCGAGCCCAGATAGTTGATGACGCGATGAACCTTGCTCTGACCGGTCGTTTGGACTACAAGACGGCCTTGGACGTGGTCAGCTACCTCGCCCATGAACGCAGCTACGTACCATGGAAGGCCGGTCTTTCTGCCCTTGGCTATATTGACACCATGCTGTCAAATGGAGAGCATTATGTGGAATACGGGATATACGTTGATCGGCTGCTACAAGGGGCCATCAGAGATGTCGGATGGGACATTCGAGAAGACGAGAGTGTTATAACGGCCCAGCACAGGGTGGATCTCTGGGCATCGGCGTGCCATTTCGAGAATTCAGACTGCATACAGAATGCTATTATATCATTCAAGAATTGGAGCACTTCTCCTGACCCTGACCGCTTTAATGATATACCGGTGGACGTGCGCGGGATAGTGTACTGCATGGCGCTGCGGCTGGGCGGCGTCAGCGAGTGGCAGTTCGCGCTGGACCGCCTCCCCGCCGCCGCGCCCGCCGAGCGACACCGCCTGCTCTCCGTGCTCGGCTGCACCAGGACCCCGCACCTACTGCGCAGGTACTTGGACATGTCATTGCGGAACGACAGTGGCATACGGAAGCAGGACGTGGTGCGGGTCTTCTCTGCTGTCTCCAACACTGCCATAGGACAGCCCATATCCTTCAGCTTCATCAGAGAGAACTGGCAGAATATCAGAACGTATTTCGGGTCAATATCAACTTTAAACCACATCGTGAAGGTCGTGACTCGCAGACTGAATCTACAACATGAATATGAAGAGCTGAAGAGGTTCGTCTCGGAGTCTTGTAGCGACCTGGGACGTCCAGTGCGGCAGGTCCTGGAGACAGTACACGCGAACGTTCAGTGGAGAAATAGAAATTATCAAACCATTGTAGATTGGCTGCAGGAAGTTAATAAAAAATACAAGGCTTAA
Protein
MQTHEPLNVVDGTTKTERGIILSKPLVLFIFVIFVLTLVTSSLLVYNFAACPKTDQLANVTKYELCRVAEAKLSLNETNKDIPKDRNIEANDKKSATERNIAISKNEIEKVKDAEGKDVMNDTNLETPKEFRLPQNVKPENYYLNITPFFLENNFTFQGEVTILLTVFNETNEIIFHGVDLVFRDLKLLTEKDRRIIDILKTEEDKLRQFHTVTVRDKLEVGMQYLLVISYSGVLNDDLHGFYRSSYEDGGVRKWIAVTQFQAMDARRAFPCWDEPAMKARFTITIGRPANMTSLSNMNSIKQSPHDSVEGYINDFYEESLPMSTYLVAFAVTDFSSKSKDTFSVWARHKVLPAASFALEIGSKILKFLENYYDIKFPLPKIDMIALPDFKNGAMENWGLLTFREIAMLYQQGVSATMDKVHVATVVAHEIAHQWFGNLVTPSWWRDLWLNEGFATYVEYVAVDAVEKSWNLTELCILDQVHNVFQLDALNSSHQLSVDVTASEETDAIFDKISYGKGAALLRMLNHILTDDIFNAGVTNYLKSKMYGNAEQKDLWAALTAVATQRNLKIDVAVVMDSWTLQTGFPVLTVNRDYGNQQIKFSQERFVLINETSSSQQAPLWWIPVSYTTASEQDFRSTRPKFWLEGVQSVVKDFPVKNEDWLIVNIQETGFYRVNYDTRNWQLLTAVLNDKNRFQEIHVINRAQIVDDAMNLALTGRLDYKTALDVVSYLAHERSYVPWKAGLSALGYIDTMLSNGEHYVEYGIYVDRLLQGAIRDVGWDIREDESVITAQHRVDLWASACHFENSDCIQNAIISFKNWSTSPDPDRFNDIPVDVRGIVYCMALRLGGVSEWQFALDRLPAAAPAERHRLLSVLGCTRTPHLLRRYLDMSLRNDSGIRKQDVVRVFSAVSNTAIGQPISFSFIRENWQNIRTYFGSISTLNHIVKVVTRRLNLQHEYEELKRFVSESCSDLGRPVRQVLETVHANVQWRNRNYQTIVDWLQEVNKKYKA

Summary

Cofactor
Zn(2+)
Similarity
Belongs to the peptidase M1 family.
EC Number
3.4.11.-
EMBL
ODYU01000825    SOQ36186.1    KZ149969    PZC76123.1    NWSH01003997    PCG65583.1    + More
AGBW02014405    OWR41732.1    KQ461198    KPJ05978.1    KQ459185    KPJ03377.1    RSAL01000014    RVE53196.1    NWSH01007621    PCG62886.1    GL446946    EFN87052.1    GL440629    EFN65601.1    GFDL01002220    JAV32825.1    GFDL01002200    JAV32845.1    ATLV01025918    KE525402    KFB52686.1    ADTU01007781    ADTU01007782    ADTU01007783    JXUM01050786    JXUM01050787    JXUM01050788    JXUM01050789    KQ561662    KXJ77885.1    KQ981905    KYN33597.1    CH477360    EAT42699.1    KK107589    EZA48634.1    NNAY01001852    OXU22728.1    QOIP01000001    RLU27566.1    KZ288223    PBC31977.1    AXCN02001184    NEVH01006570    PNF37828.1    AAAB01008888    EGK97116.1    KQ435724    KOX78330.1    KQ414710    KOC62990.1    APCN01003169    ADMH02001252    ETN63471.1    KQ976467    KYM84197.1    KQ980713    KYN14242.1    AJWK01011047    AJWK01011048    AJWK01011049    UFQS01000655    UFQT01000655    SSX05824.1    SSX26183.1    SSX05825.1    SSX26184.1    SSX05823.1    SSX26182.1    SSX05822.1    SSX26181.1    GFDF01001172    JAV12912.1    GFDF01001171    JAV12913.1    KK853596    KDR06435.1    KQ977935    KYM98719.1    KQ982649    KYQ53113.1    GEDC01023029    GEDC01011996    JAS14269.1    JAS25302.1    JRES01000835    KNC27946.1    GAKP01020867    JAC38085.1    GL887532    EGI70840.1    KYN14241.1    GL771642    EFZ09701.1    GDHF01028490    GDHF01018031    GDHF01005941    JAI23824.1    JAI34283.1    JAI46373.1    DS235745    EEB16227.1    GBXI01017159    JAC97132.1    GDKW01001137    JAI55458.1    KK854013    PTY09335.1    GBGD01000333    JAC88556.1    GFTR01008371    JAW08055.1    KQ434984    KZC13132.1    GEBQ01009519    JAT30458.1    GDHC01006045    JAQ12584.1    GECL01002882    JAP03242.1    GECZ01002996    JAS66773.1    KA644849    AFP59478.1    ACPB03005577    GEZM01062043    JAV70095.1    GEZM01062044    JAV70094.1    CM000070    KRT00027.1    EDY67826.1    CP012526    ALC47212.1    GEDC01003748    JAS33550.1    CH479179    EDW24026.1    OUUW01000005    SPP80599.1    KQ971311    EEZ99360.2    CH902623    EDV30438.1    KPU72858.1    GAMC01012267    JAB94288.1    CH964232    EDW81128.2    CH940650    EDW68007.1    CH933806    EDW15450.1    CVRI01000044    CRK96557.1    KYM84198.1    AE014297    AAN14161.2    KQ760397    OAD60666.1    CH916374    EDV91456.1   
Pfam
PF01433   Peptidase_M1        + More
PF11838   ERAP1_C
PF00089   Trypsin
Interpro
IPR034016   M1_APN-typ        + More
IPR001930   Peptidase_M1       
IPR033581   APN2       
IPR024571   ERAP1-like_C_dom       
IPR014782   Peptidase_M1_dom       
IPR042097   Aminopeptidase_N-like_N       
IPR009003   Peptidase_S1_PA       
IPR001254   Trypsin_dom       
IPR038565   CLIP_sf       
IPR022700   CLIP       
SUPFAM
SSF50494   SSF50494       
Gene 3D
PDB
5LDS     E-value=1.10025e-155,     Score=1415

Ontologies

Topology

Length:
1009
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
22.53431
Exp number, first 60 AAs:
22.3693
Total prob of N-in:
0.99418
POSSIBLE N-term signal
sequence
inside
1  -  25
TMhelix
26  -  48
outside
49  -  1009
 
 

Population Genetic Test Statistics

Pi
169.673173
Theta
152.831283
Tajima's D
-1.519217
CLR
1.8843
CSRT
0.0580970951452427
Interpretation
Uncertain
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