Gene

KWMTBOMO04875  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA008050

Annotation

transgelin_[Antheraea_yamamai]

Location

Bomo_Chr9(+):700206-700867      View in EpiBrowser

Full name

Transgelin       + More
Calponin      

Location in the cell

Cytoplasmic   Reliability : 2.036 Nuclear   Reliability : 1.934

CDS

ATGGCCGAGTATCGCGCAGGAAAAGCTGGCATCAACGCCGAAGCCCAGGCCAGGATCCACAGTAAATACAACGATGAAATCGCCCAAGAAACCCTCGAGTGGATCAGGAAATTGACCGGCGAACCGGCCAACACCTCCGGTGACGCCGACAACCTGTACGAAGTCTTAAAAGACGGCACCCTCCTCTGCAAACTAGTCAACGAGCTTCAACCAGGTTCCGTTAAGAAGATCAACCAAACGACCATGGCCTTCAAGTGTATGGAGAACATAAACGCTTTCCTAGAGGCAGTCAAGAAGCTAGGCGTGCCCGCTCAGGAGACCTTCCAGACCATTGATCTTTGGGAGAGGCAGAACCTTTACTCGGTGGTCGTTTGTCTACAGTCCCTCGGTAGGAAGGCAGGTAACTTCGGCAAGCCGTCCATCGGGCCCAAGGAGGCGGACAAGAATGTGCGCGACTTCTCCGAGGAGCAGCTGAAAGCCGGTCAGAACGTGATATCGCTACAGTACGGCACTAACAAGGGCCAGCAGTCGGGCATATCCTTCGGCAACAGGCGTCAAATGTGA

Protein

MAEYRAGKAGINAEAQARIHSKYNDEIAQETLEWIRKLTGEPANTSGDADNLYEVLKDGTLLCKLVNELQPGSVKKINQTTMAFKCMENINAFLEAVKKLGVPAQETFQTIDLWERQNLYSVVVCLQSLGRKAGNFGKPSIGPKEADKNVRDFSEEQLKAGQNVISLQYGTNKGQQSGISFGNRRQM

Description

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Similarity

Belongs to the calponin family.

Uniprot

H9JEV3   G8FVP3   A0A2A4ISJ9   A0A2H1X2F6   A0A194QCW4   A0A0L7KN16   + More
A0A194QM03   A0A2W1BSE2   A0A1E1WIV4   A0A0K8SXC1   F8R4Z6   A0A212EJR1   A0A3S2TPH9   A0A1E1WN47   A0A194QTM3   I4DNE6   A0A212FDZ4   S4PMM4   Q1HQ70   A0A2A4J0G7   A0A2H1VJF7   B4L9E1   A0A2A3EBY9   V9IDZ7   A0A088AJ47   B3M4V0   A0A1W4W6W8   W8BCE9   A0A195EZC6   Q29D85   B4H7U8   A0A1B0GIN7   A0A3B0J6R8   B4LB83   A0A0M3QWF1   B4N3J5   A0A3L8DZH0   A0A158NDR9   A0A0C9QLT0   A0A0K8TZF1   A0A034WQN6   A0A1B6FMU2   A0A1L8EIE7   A0A0L0BR69   A0A1B6IPQ6   B4J1D9   A0A0J9RP62   B4PHP6   B4HU00   B3NG36   Q9VZI1   D3TSC5   A0A1B6L9J9   A0A0A1XN87   A0A1W4W8P8   A0A1I8P873   A0A1I8P874   R4UW18   A0A1L8E5Z6   A0A1I8NH87   U5EYQ9   A0A0A9WIH3   R4WR80   A0A023F9W3   A0A182NQJ8   V5GZ80   A0A170ZFV1   K7ISL6   A0A182RNK3   A0A0Q9XGY5   A0A1B6CS28   A0A182Q8Q7   A0A182VVS7   A0A182X9L4   A0A182VDH7   A0A182HKJ7   Q7PXA9   A0A069DPP4   T1DIU2   A0A336KB30   H9JC47   A0A0N8P109   A0A1J1II95   T1DN20   A0A2M3Z084   A0A2M4A8L1   A0A087ZJX0   A0A1L8EEX8   A0A1B0GQB3   A0A0L7R7U5   A0A1Q3EUJ0   A0A0R3P732   A0A0Q9WT59   A0A0K8TPC4   A0A224XXM0   A0A3B0JVN5   A0A0Q9WSE1   W8BSV8   Q1HR19   A0A023EJ28  

Pubmed

19121390    26354079    26227816    28756777    21625546    22118469    + More
22651552    23622113    17994087    24495485    15632085    30249741    21347285    25348373    26108605    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20353571    25830018    25315136    25401762    26823975    23691247    25474469    20075255    12364791    14747013    17210077    26334808    24330624    20920257    26369729    17204158    17510324    24945155   

EMBL

BABH01023365    JN082713    AER27811.1    NWSH01007453    PCG62967.1    ODYU01012876    + More
SOQ59396.1    KQ459185    KPJ03383.1    JTDY01008557    KOB64515.1    KQ461198    KPJ05985.1    KZ149969    PZC76107.1    GDQN01004263    JAT86791.1    GBRD01007873    JAG57948.1    HM490090    ADM47613.1    AGBW02014406    OWR41727.1    RSAL01000031    RVE51633.1    GDQN01002778    JAT88276.1    KQ461137    KPJ08817.1    AK402870    KQ459603    BAM19436.1    KPI93065.1    AGBW02008995    OWR51940.1    GAIX01000101    JAA92459.1    DQ443182    ABF51271.1    NWSH01003936    PCG65657.1    ODYU01002898    SOQ40965.1    CH933816    EDW17316.1    KZ288290    PBC29238.1    JR041079    AEY59353.1    CH902618    EDV40524.1    GAMC01010188    JAB96367.1    KQ981906    KYN33262.1    CH379070    EAL30529.2    CH479219    EDW34738.1    AJWK01015120    AJWK01015121    AJWK01015122    OUUW01000002    SPP77425.1    CH940647    EDW68647.1    CP012525    ALC44039.1    CH964095    EDW79200.1    QOIP01000002    RLU25329.1    ADTU01012849    ADTU01012850    ADTU01012851    GBYB01004509    GBYB01011628    JAG74276.1    JAG81395.1    GDHF01032661    JAI19653.1    GAKP01002447    JAC56505.1    GECZ01018242    JAS51527.1    GFDG01000374    JAV18425.1    JRES01001494    KNC22483.1    GECU01018823    JAS88883.1    CH916366    EDV95830.1    CM002912    KMY97497.1    CM000159    EDW93355.1    CH480817    EDW50421.1    CH954178    EDV50865.1    AF217286    AE014296    AY060355    AAF44064.1    AAF47840.2    AAL25394.1    EZ424327    ADD20603.1    GEBQ01019588    JAT20389.1    GBXI01002244    JAD12048.1    KC571917    AGM32416.1    GFDF01000152    JAV13932.1    GANO01001867    JAB58004.1    GBHO01036398    GBRD01016895    GDHC01000434    JAG07206.1    JAG48932.1    JAQ18195.1    AK417172    BAN20387.1    GBBI01000923    JAC17789.1    GALX01001249    JAB67217.1    GEMB01002249    JAS00931.1    KRG07727.1    GEDC01021255    JAS16043.1    AXCN02001518    APCN01000834    AAAB01008987    EAA01312.4    GBGD01003099    JAC85790.1    GALA01000756    JAA94096.1    UFQS01000192    UFQT01000192    SSX01032.1    SSX21412.1    BABH01014894    KPU78612.1    CVRI01000048    CRK98774.1    GAMD01003245    JAA98345.1    GGFM01001184    MBW21935.1    GGFK01003815    MBW37136.1    GGFL01004380    MBW68558.1    GFDG01001551    JAV17248.1    AJVK01036080    KQ414637    KOC66950.1    GFDL01016119    JAV18926.1    KRT09031.1    KRF83950.1    GDAI01001366    JAI16237.1    GFTR01003134    JAW13292.1    SPP77426.1    KRF99024.1    GAMC01010189    JAB96366.1    DQ440275    CH477412    ABF18308.1    EAT41438.1    GAPW01004775    GAPW01004774    JAC08824.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000037510    UP000053240    UP000007151    + More
UP000283053    UP000009192    UP000242457    UP000005203    UP000007801    UP000192221    UP000078541    UP000001819    UP000008744    UP000092461    UP000268350    UP000008792    UP000092553    UP000007798    UP000279307    UP000005205    UP000037069    UP000001070    UP000002282    UP000001292    UP000008711    UP000000803    UP000192223    UP000095300    UP000095301    UP000075884    UP000002358    UP000075900    UP000075886    UP000075920    UP000076407    UP000075903    UP000075840    UP000007062    UP000183832    UP000092462    UP000053825    UP000008820   

PRIDE

H9JEV3    Q1HQ70    Q9VZI1    H9JC47   

Pfam

PF00402   Calponin        + More
PF00307   CH

Interpro

IPR000557   Calponin_repeat        + More
IPR003096   SM22_calponin       
IPR001715   CH-domain       
IPR036872   CH_dom_sf       
IPR001997   Calponin/LIMCH1       

SUPFAM

SSF47576   SSF47576       

Gene 3D

1.10.418.10    

CDD

cd00014  CH

ProteinModelPortal

H9JEV3   G8FVP3   A0A2A4ISJ9   A0A2H1X2F6   A0A194QCW4   A0A0L7KN16   + More
A0A194QM03   A0A2W1BSE2   A0A1E1WIV4   A0A0K8SXC1   F8R4Z6   A0A212EJR1   A0A3S2TPH9   A0A1E1WN47   A0A194QTM3   I4DNE6   A0A212FDZ4   S4PMM4   Q1HQ70   A0A2A4J0G7   A0A2H1VJF7   B4L9E1   A0A2A3EBY9   V9IDZ7   A0A088AJ47   B3M4V0   A0A1W4W6W8   W8BCE9   A0A195EZC6   Q29D85   B4H7U8   A0A1B0GIN7   A0A3B0J6R8   B4LB83   A0A0M3QWF1   B4N3J5   A0A3L8DZH0   A0A158NDR9   A0A0C9QLT0   A0A0K8TZF1   A0A034WQN6   A0A1B6FMU2   A0A1L8EIE7   A0A0L0BR69   A0A1B6IPQ6   B4J1D9   A0A0J9RP62   B4PHP6   B4HU00   B3NG36   Q9VZI1   D3TSC5   A0A1B6L9J9   A0A0A1XN87   A0A1W4W8P8   A0A1I8P873   A0A1I8P874   R4UW18   A0A1L8E5Z6   A0A1I8NH87   U5EYQ9   A0A0A9WIH3   R4WR80   A0A023F9W3   A0A182NQJ8   V5GZ80   A0A170ZFV1   K7ISL6   A0A182RNK3   A0A0Q9XGY5   A0A1B6CS28   A0A182Q8Q7   A0A182VVS7   A0A182X9L4   A0A182VDH7   A0A182HKJ7   Q7PXA9   A0A069DPP4   T1DIU2   A0A336KB30   H9JC47   A0A0N8P109   A0A1J1II95   T1DN20   A0A2M3Z084   A0A2M4A8L1   A0A087ZJX0   A0A1L8EEX8   A0A1B0GQB3   A0A0L7R7U5   A0A1Q3EUJ0   A0A0R3P732   A0A0Q9WT59   A0A0K8TPC4   A0A224XXM0   A0A3B0JVN5   A0A0Q9WSE1   W8BSV8   Q1HR19   A0A023EJ28  

PDB

1WYM     E-value=4.27899e-17,     Score=211

KEGG

101735683    K20526 transgelin | (RefSeq) myophilin-like

GO

GO:0031032   GO:0003779   GO:0005516   GO:0035626   GO:0070594   GO:0005865   GO:0006939   GO:0005515   GO:0008270   GO:0004190   GO:0006508   GO:0015074   GO:0007166   GO:0006032   GO:0016742   GO:0003824  

Length:

187

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00018

Exp number, first 60 AAs:

0

Total prob of N-in:

0.29737

outside

1  -  187

 

 

Pi

211.056842

Theta

208.080043

Tajima's D

0.045037

CLR

0

CSRT

0.384380780960952

Interpretation

Uncertain