SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO04835  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA013945
Annotation
actin?_muscle-type_A2_[Bombyx_mori]
Full name
Actin, muscle-type A2       + More
Actin, indirect flight muscle      
Alternative Name
Actin-88F
Location in the cell
Cytoplasmic   Reliability : 3.817
 

Sequence

CDS
ATGTGTGACGATGATGCGGGCGCGCTCGTCGTCGACAACGGATCCGGCATGTGCAAGGCTGGATTCGCGGGGGACGACGCCCCTCGAGCCGTGTTCCCTTCCATAGTGGGCCGCCCGCGCCACCAGGGCGTCATGGTCGGCATGGGCCAAAAAGATTCGTATGTAGGTGACGAAGCCCAGAGCAAGAGAGGTATCCTCACTCTAAAGTACCCCATCGAGCACGGGATAATCACCAACTGGGATGACATGGAGAAGATCTGGCATCACACGTTCTACAATGAGCTGCGCGTCGCTCCCGAAGAGCACCCAATCCTGCTGACCGAGGCGCCCCTGAACCCGAAGGCCAACAGAGAGAAGATGACTCAGATCATGTTCGAGACGTTCAATTGTCCCGCCATGTACGTCGCCATCCAGGCCGTGCTCTCGCTCTACGCCTCCGGTCGTACCACCGGCATCGTGCTCGACTCCGGAGACGGTGTCTCCCACACCGTACCCATCTACGAAGGCTATGCGCTGCCCCACGCCATTCTCCGTCTGGACTTGGCCGGACGCGACTTGACTGACTACCTCATGAAGATCCTCACCGAGAGGGGCTACTCGTTCACTACCACTGCCGAGAGGGAAATCGTCCGCGACATCAAGGAGAAGCTGTGTTATGTCGCTCTCGACTTTGAGCAGGAAATGCAGACTGCGGCCGCTTCAACCTCTCTGGAGAAATCCTACGAGCTACCAGACGGACAGGTGATCACCATCGGCAACGAGCGCTTCCGGTGTCCCGAGGCTCTGTTCCAACCCTCGTTCCTGGGTATGGAGTCGTGCGGCATCCACGAGACCGTGTACAACTCGATTATGAAGTGCGACGTGGACATCCGCAAGGACCTGTACGCCAACACGGTGCTGTCGGGCGGCACGACCATGTACCCCGGTATCGCCGACAGGATGCAGAAGGAGATCACCGCCCTCGCGCCCTCGACCATCAAGATCAAGATCATCGCTCCCCCCGAGAGGAAGTATTCCGTGTGGATCGGCGGCTCGATCCTGGCGTCGCTGTCCACCTTCCAGCAGATGTGGATCTCGAAGCAGGAGTACGACGAGTCCGGGCCGGGCATCGTTCACCGCAAGTGCTTCTAA
Protein
MCDDDAGALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNCPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAAASTSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF

Summary

Miscellaneous
There are at least 5 different actin genes in this organism.
In Drosophila there are 6 closely related actin genes.
Abnormalities in Act88F-ifm(3)7 flight muscles result from incorporation of the mutant actin isoform into assembling myofibrils.
Similarity
Belongs to the actin family.
Keywords
Acetylation   ATP-binding   Complete proteome   Cytoplasm   Cytoskeleton   Nucleotide-binding   Oxidation   Reference proteome   Methylation   Muscle protein  
Feature
propeptide  Removed in mature form
chain  Actin, muscle-type A2
EMBL
KZ150126    PZC73116.1    NWSH01003858    PCG65750.1    ODYU01007534    SOQ50387.1    + More
X06363    JF417981    AEB26312.1    AJ292554    GDIP01175048    GDIP01175045    GDIQ01130636    GDIP01129717    GDIP01037836    GDIQ01037496    GDIQ01037495    CAB99474.1    JAJ48354.1    JAL21090.1    GL732524    GL732523    EFX89657.1    EFX89901.1    JTDY01006084    KOB66311.1    CVRI01000015    CRK90035.1    GDIQ01268830    JAJ82894.1    GDIP01175046    JAJ48356.1    GDIP01186521    JAJ36881.1    GDIP01149442    GDIP01149441    JAJ73961.1    AK358850    BAJ90061.1    GFTR01005593    JAW10833.1    AY725778    AAU95191.1    CCAG010013799    DQ206832    ABA62321.1    KU196670    AMD16550.1    KY038869    ATP16752.1    GFXV01006509    MBW18314.1    AB509262    BAI77996.1    MG993326    AYU58903.1    KU188517    ANE06405.1    OUUW01000007    SPP82975.1    GDKW01000574    JAI56021.1    JXJN01017519    CM000070    EDY67713.1    KT369806    AML25535.1    BT050557    ACJ13264.1    AY737550    AAU84943.1    CM000160    EDW97442.1    GECL01003587    JAP02537.1    ABLF02032889    GEMB01002235    JAS00945.1    AY588061    AAT01073.1    NEVH01003508    PNF40452.1    DQ450899    ABE27979.1    KK853207    KDR09838.1    KC161211    AGJ76539.1    AM850110    CAO98769.1    KX108734    ANV22067.1    CH902617    EDV43074.1    CH964232    EDW80633.1    JRES01000563    KNC30170.1    KU196668    AMD16548.1    FX983744    BAX07243.1    CH954181    EDV49023.1    GDIP01142223    JAL61491.1    GEZM01048387    GEZM01048386    JAV76591.1    ACPB03021529    GAHY01000509    JAA77001.1    EU179846    EU179847    EU179848    ABY48093.1    ABY48095.1    GDIP01175047    GDIP01170376    JAJ53026.1    GECZ01027298    GECZ01011797    JAS42471.1    JAS57972.1    KA646663    KA646664    AFP61293.1    DS235250    EEB13950.1    GEDC01023461    GEDC01016965    GEDC01002583    JAS13837.1    JAS20333.1    JAS34715.1    GBHO01044314    GBRD01005390    JAF99289.1    JAG60431.1    M87274    CM000364    M18826    K02065    AB003910    AE014297    M18830    L12253    GFDF01000313    JAV13771.1    AJVK01003905    KQ978931    KYN27466.1    MG983770    AWV96605.1    KQ976462    KYM84633.1    AAZX01005009    KJ192330    AHW40461.1    KQ981204    KYN44932.1    MG264369    AVT69429.1    ADTU01003540    ADTU01003541    GDIP01170424    JAJ52978.1    MG243593    AXU38338.1    KQ983089    KYQ47686.1    GDIP01175044    GDIP01170375    JAJ53027.1    GDIP01170377    JAJ53025.1    GFDF01000312    JAV13772.1    AAAB01008956    EAA10668.4    GDIP01143275    JAJ80127.1    GGFK01010774    MBW44095.1    KP704257    AKO62881.1    AY817141    AAV65298.1    GALX01004399    JAB64067.1    KF792064    AHH25009.1    KQ971319    EFA00468.1    KJ507199    AHY22050.1    GQ389791    ACV32627.1    GDIP01150736    JAJ72666.1    KK107013    EZA62930.1    APGK01027120    KB740648    KB632292    ENN79784.1    ERL91608.1    KU521368    KX428475    ANS71248.1    ANW09586.1   
Pfam
PF00022   Actin
Interpro
IPR020902   Actin/actin-like_CS        + More
IPR004000   Actin       
IPR004001   Actin_CS       
PDB
5CE3     E-value=0,     Score=1999

Ontologies

Topology

Subcellular location
  
Length:
376
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
1.35323
Exp number, first 60 AAs:
0.00115
Total prob of N-in:
0.05368
outside
1  -  376
 
 

Population Genetic Test Statistics

Pi
4.820552
Theta
6.298703
Tajima's D
-0.374478
CLR
0.495425
CSRT
0.28243587820609
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
26280517 YMNVDVVKQFMEMYK 96.30 3e-16
27102218 YPIEHGIITNWDDMEK 96.30 3e-16
28556443 CPEALFQPSFLGMESCGIHETVYNSIMK 100.00 3e-15
28556443 CPEALFQPSFLGMESCGIHETVYNSIMK 100.00 3e-15
28556443 CPEALFQPSFLGMESCGIHETVYNSIMK 100.00 3e-15
28556443 CPEALFQPSFLGMESCGIHETVYNSIMK 100.00 3e-15
28556443 CPEALFQPSFLGM 100.00 3e-15
28556443 ANTVMSGGTTMYPGIADR 100.00 3e-15
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPHAILR 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 2e-14
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGY 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGYALPH 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGY 100.00 1e-11
28556443 TTGIVLDSGDGVSHTVPIYEGY 100.00 1e-11
28556443 YSFTTTAER 100.00 1e-09
28467696 HQGVMVGMGQK 100.00 3e-09
28556443 FLGMEANGIHETTYNSIMK 100.00 3e-09
28556443 KDLYANTVLSGGTTMYPGIADR 100.00 3e-09
28556443 KDLYANTVLSGGTTMYPGIADR 100.00 3e-09
28556443 KDLYANTVLSGGTTMYPGIADR 100.00 3e-09
28556443 KDLYANTVLSGGTTMYPGIADR 100.00 3e-09
28556443 IWHHTFYNELR 100.00 3e-09
28556443 HQGVMVGMGQK 100.00 3e-09
28556443 LTEAPLNPK 95.45 7e-09
28556443 VAPEEHPVLLTEAPLNPKANR 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPKANR 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPKANR 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPKANR 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPK 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPKANR 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPKANR 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPKANR 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPK 95.24 1e-08
28556443 VAPEEHPVLLTEAPLNPK 95.24 1e-08
28556443 KDLYANTVMSGGTTMYPGIADR 95.45 1e-08
28556443 KDLYANTVMSGGTTMYPGIADR 95.45 1e-08
28556443 KDLYANTVMSGGTTMYPGIADR 95.45 1e-08
28556443 IWHHTFYNELR 95.45 1e-08
28556443 IWHHTFYNELR 95.45 1e-08
28556443 TTGIVLDSGDGVSHTVPIYEGY 100.00 1e-08
28556443 TTGIVLDSGDGVSH 100.00 1e-08
28556443 TTGIVLDSGDGVSH 100.00 1e-08
28556443 SYELPDGQVITIGNER 100.00 1e-08
28556443 KDLYANTVMSGGTTMYPGIADR 95.65 2e-08
28556443 KDLYANTVMSGGTTMYPGIADR 95.65 2e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DLYANTVLSGGTTMYPGIADR 100.00 3e-08
28556443 DFEQEMATAASSSSLEK 100.00 3e-08
28556443 CPEALFQPSFLGMEANGIHETTYNSIMK 100.00 3e-08
28556443 GILTLKYPIEHGIITNWDDMEK 100.00 5e-08
21761556 AGFAGDDAPR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLYANTVMSGGTTMYPGIADR 95.24 6e-08
28556443 DLTDYLMK 95.24 6e-08
28556443 DLTDYLMK 95.24 6e-08
28556443 ALPHAILR 100.00 6e-06
28556443 VLGLIETGK 100.00 6e-06
26822097 EITAIAPSTIK 100.00 9e-06
26280517 YGVSSEYFEANDEAAIK 100.00 9e-06
25044914 YPGGSVFPDIMR 100.00 9e-06
24093152 YPGPIDDSITNTDNIVIYTDPTIDTHVSR 100.00 9e-06
27102218 DSHQIDIPPFGR 100.00 9e-06
28467696 YPFSICAGEVGAGAYVAR 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 YPIEHGIITNWDDMEK 100.00 9e-06
28556443 VGDEAQSK 100.00 9e-06
28556443 VAPEEHPVLLTEAPLNPKANR 100.00 9e-06
28556443 MQKEITALAPSTMK 100.00 2e-05
28556443 LCYVALDFEQEMATAASSSSLEK 100.00 2e-05
28556443 TVPIYEGYALPHAILR 100.00 3e-05
28556443 TVPIYEGYALPHAILR 100.00 3e-05
28556443 TVPIYEGYALPH 100.00 3e-05
28556443 TVPIYEGYALPHAILR 100.00 3e-05
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