Gene

KWMTBOMO04792  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009902

Annotation

partner_of_Y14_and_mago_[Bombyx_mori]

Location

Bomo_Chr8(+):15021697-15024376      View in EpiBrowser

Full name

Partner of Y14 and mago      

Alternative Name

Protein wibg homolog
Protein within the bgcn gene intron

Location in the cell

Nuclear   Reliability : 3.363

CDS

ATGTCAACACCAACGGCTTATGAGCACGACGCTGATGGGAGTAAATTCATTCCTGCAACTCAAAGACCTGATGGAACCTGGCGCAAGCCGAGAAGAATAAAAGAAGGTTATGTACCTCAAGAAGAGGTACCGTTGTATGAAAGCAAAGGAAAACAGTTCAGGGCCAGGCAAAATGATGGACTTCCGGTTGGACTTACACCTGAGATTGTAGCTCAAGCACAAAAGAAGAAAGGTCAACGAAGCACTATCCAACCTATACCTGGAATGATTATAACTGTTGAAAAGAAGAAAAAGAAAAAGAAGACAGTTACAGGTGTTGAAGAAGCTGCAGAAAAACTTGCCAAATGTGAAATACAAGAACCAACCGTACCTAGTCAGTCAGTACCGACTGAAAGTATATCTCAGTCTGATCCGACAAAACGCCTCAAGAATCTCAGAAAAAAGCTTAGAGAAATAGAGTTTCTAGAGGAAAAAATAAAAGCAGGGCTTCTTAAGAGCCCTGATAAAGATCAAAAAGAGAAAATGTCAAAAAAGAATGAAATTTTAAATGAAATTGACATTTTAGAGAATAGTATTCTATGA

Protein

MSTPTAYEHDADGSKFIPATQRPDGTWRKPRRIKEGYVPQEEVPLYESKGKQFRARQNDGLPVGLTPEIVAQAQKKKGQRSTIQPIPGMIITVEKKKKKKKTVTGVEEAAEKLAKCEIQEPTVPSQSVPTESISQSDPTKRLKNLRKKLREIEFLEEKIKAGLLKSPDKDQKEKMSKKNEILNEIDILENSIL

Description

Regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.
Regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor by disrupting mature EJC from spliced mRNAs. Required for normal localization of osk mRNA to the posterior pole of the developing oocyte. Does not interact with the small ribosomal unit or components of the translation initiation complex. May not function in cap-dependent translation regulation.

Subunit

Interacts (via N-terminus) with mago and tsu/Y14; the interaction is direct.
Interacts (via N-terminus) with mago and tsu/RBM8A; the interaction is direct.

Similarity

Belongs to the pym family.
Belongs to the GroES chaperonin family.

Keywords

Coiled coil   Complete proteome   Cytoplasm   Nucleus   Reference proteome   3D-structure  

Feature

chain  Partner of Y14 and mago

Uniprot

Q2F5J3   H9JK51   A0A2H1WK89   A0A194PQP3   A0A0N1I6C9   A0A1E1W9A3   + More
A0A2A4JR05   S4PCU3   A0A212EV69   A0A0C9RUL8   A0A2J7PHK9   A0A1B6I007   A0A164Y948   A0A0P4XLG8   A0A0P5HXB9   A0A232EWZ9   A0A0P6BZD7   A0A0P5PAY5   K7J0X0   A0A0P5NYL1   A0A1B6FAA4   A0A0P6G7I6   A0A0Q9WPS1   A0A0P6GXI8   A0A1B0CB31   A0A1L8DCF5   A0A2A3E5I6   E9FYZ9   A0A088AA04   A0A0L7R6J4   A0A0Q5VW21   A0A0T6B3D3   P82804   A0A0K8TK69   B4NSP6   U5EZN3   A0A067QVG2   A0A0J9RL02   A0A1W4UMF6   E2C3R6   A0A1L8DC60   V5GKS4   D6WV11   A0A0R3NL25   A0A034WHC3   A0A0P4X209   A0A0R1DTI5   A0A1B6DNZ9   N6TPU1   A0A0P9AC03   A0A0K8UN40   T1PMB3   A0A1Y1N6T6   A0A1I8M3N1   A0A3L8E1R0   A0A2P8XEH2   A0A0M9ABK8   A0A026WEI4   A0A151WGC4   A0A158ND72   A0A195DJC2   E2AFB5   A0A151ILD8   A0A195FGS9   A0A2L2Y7J5   A0A1S3K099   A0A195B0S7   A0A2T7PAM5   A0A2R5LN60   A0A1W4XCU5  

Pubmed

19121390    26354079    23622113    22118469    28648823    20075255    + More
17994087    21292972    10924476    12483225    10731132    12537572    12537569    24967911    14968132    26369729    24845553    22936249    20798317    18362917    19820115    15632085    25348373    17550304    23537049    28004739    25315136    30249741    29403074    24508170    21347285    26561354   

EMBL

DQ311430    BABH01026667    ODYU01009206    SOQ53469.1    KQ459595    KPI95766.1    + More
KQ461192    KPJ07059.1    GDQN01007464    JAT83590.1    NWSH01000843    PCG73883.1    GAIX01003971    JAA88589.1    AGBW02012233    OWR45379.1    GBYB01011290    GBYB01011291    JAG81057.1    JAG81058.1    NEVH01025135    PNF15815.1    GECU01027454    JAS80252.1    LRGB01000930    KZS15007.1    GDIP01240902    JAI82499.1    GDIQ01227407    JAK24318.1    NNAY01001806    OXU22870.1    GDIP01008340    JAM95375.1    GDIQ01137145    JAL14581.1    GDIQ01145946    JAL05780.1    GECZ01022600    JAS47169.1    GDIQ01040133    JAN54604.1    CH963850    KRF98138.1    GDIQ01027817    JAN66920.1    AJWK01004787    GFDF01009945    JAV04139.1    KZ288361    PBC26960.1    GL732527    EFX87683.1    KQ414646    KOC66444.1    CH954179    KQS63061.1    LJIG01016005    KRT81900.1    AF293388    AJ459405    AE013599    AY070957    AY071704    AAG00610.1    GDAI01002956    JAI14647.1    CH982397    GANO01000470    JAB59401.1    KK853329    KDR08434.1    CM002911    KMY96134.1    GL452364    EFN77302.1    GFDF01010119    JAV03965.1    GALX01006244    JAB62222.1    KQ971357    EFA08334.1    CM000071    KRT01572.1    GAKP01005397    JAC53555.1    GDRN01020005    JAI67817.1    CM000158    KRK00492.1    GEDC01009911    JAS27387.1    APGK01057053    KB741277    KB631617    ENN71265.1    ERL84715.1    CH902619    KPU75687.1    GDHF01024190    JAI28124.1    KA649048    AFP63677.1    GEZM01011168    JAV93614.1    QOIP01000001    RLU26393.1    PYGN01002487    PSN30407.1    KQ435700    KOX80496.1    KK107260    EZA54071.1    KQ983185    KYQ46855.1    ADTU01012469    KQ980800    KYN12917.1    GL439108    EFN67808.1    KQ977146    KYN05301.1    KQ981560    KYN39890.1    IAAA01018761    LAA04123.1    KQ976690    KYM78083.1    PZQS01000005    PVD30463.1    GGLE01006844    MBY10970.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000218220    UP000007151    UP000235965    + More
UP000076858    UP000215335    UP000002358    UP000007798    UP000092461    UP000242457    UP000000305    UP000005203    UP000053825    UP000008711    UP000000803    UP000000304    UP000027135    UP000192221    UP000008237    UP000007266    UP000001819    UP000002282    UP000019118    UP000030742    UP000007801    UP000095301    UP000279307    UP000245037    UP000053105    UP000053097    UP000075809    UP000005205    UP000078492    UP000000311    UP000078542    UP000078541    UP000085678    UP000078540    UP000245119    UP000192223   

PRIDE

Q2F5J3    H9JK51    P82804    B4NSP6   

Pfam

PF09282   Mago-bind        + More
PF00166   Cpn10

Interpro

IPR015362   WIBG_mago-bd        + More
IPR039333   PYM1       
IPR036348   WIBG_N_sf       
IPR037124   Chaperonin_GroES_sf       
IPR011032   GroES-like_sf       
IPR020818   Chaperonin_GroES       

SUPFAM

SSF101931   SSF101931        + More
SSF50129   SSF50129       

Gene 3D

2.30.33.40    

CDD

cd00320  cpn10

ProteinModelPortal

Q2F5J3   H9JK51   A0A2H1WK89   A0A194PQP3   A0A0N1I6C9   A0A1E1W9A3   + More
A0A2A4JR05   S4PCU3   A0A212EV69   A0A0C9RUL8   A0A2J7PHK9   A0A1B6I007   A0A164Y948   A0A0P4XLG8   A0A0P5HXB9   A0A232EWZ9   A0A0P6BZD7   A0A0P5PAY5   K7J0X0   A0A0P5NYL1   A0A1B6FAA4   A0A0P6G7I6   A0A0Q9WPS1   A0A0P6GXI8   A0A1B0CB31   A0A1L8DCF5   A0A2A3E5I6   E9FYZ9   A0A088AA04   A0A0L7R6J4   A0A0Q5VW21   A0A0T6B3D3   P82804   A0A0K8TK69   B4NSP6   U5EZN3   A0A067QVG2   A0A0J9RL02   A0A1W4UMF6   E2C3R6   A0A1L8DC60   V5GKS4   D6WV11   A0A0R3NL25   A0A034WHC3   A0A0P4X209   A0A0R1DTI5   A0A1B6DNZ9   N6TPU1   A0A0P9AC03   A0A0K8UN40   T1PMB3   A0A1Y1N6T6   A0A1I8M3N1   A0A3L8E1R0   A0A2P8XEH2   A0A0M9ABK8   A0A026WEI4   A0A151WGC4   A0A158ND72   A0A195DJC2   E2AFB5   A0A151ILD8   A0A195FGS9   A0A2L2Y7J5   A0A1S3K099   A0A195B0S7   A0A2T7PAM5   A0A2R5LN60   A0A1W4XCU5  

PDB

1RK8     E-value=7.2472e-14,     Score=183

KEGG

692986    K14294 partner of Y14 and mago | (RefSeq) wibg, PYM; Wibg protein

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)
03015    mRNA surveillance pathway - Bombyx mori (domestic silkworm)

GO

GO:0005737   GO:0035145   GO:1903259   GO:0000184   GO:0016021   GO:0003723   GO:1990448   GO:0006457  

PANTHER

PTHR22959  

Subcellular location

Cytoplasm   Shuttles between the nucleus and the cytoplasm. Nuclear export is mediated by emb/Crm1 (By similarity).   With evidence from 1 publications.
Nucleus   Shuttles between the nucleus and the cytoplasm. Nuclear export is mediated by emb/Crm1 (By similarity).   With evidence from 1 publications.

Length:

193

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.12557

outside

1  -  193

 

 

Pi

26.387054

Theta

22.563663

Tajima's D

0.559719

CLR

2.667231

CSRT

0.539923003849808

Interpretation

Uncertain