Gene

KWMTBOMO04776  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009893

Annotation

exosome_complex_exonuclease_Rrp40_[Bombyx_mori]

Location

Bomo_Chr8(+):14689078-14689858      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.514 Mitochondrial   Reliability : 1.412

CDS

ATGAACGTTTCAATAGATGATGTAGTTTTACCTGGAGATCACTGTCCAGAGATCGTGGCGGCTGGCGAAAAAGGAAAAGTTCTACTAGGTCCTGGACTTCGCAAAGAAATTAACGGTGTTTTTATAACAAAACCAGGCGTATTACGGAAACGAACACCAAATACATACTGGGTGGACAATTATCAGAAGCGCTATGTGCCTTCTAGAGGTGAAAATGTGATCGGTACCGTGGTACAGAAAGCGGGCGATATTTTCCGTGTGGACGTCGGGGGGAGTTGTGCCGCATCGCTGTCATATCTGTCGTTCGAAGGAGCGACGAAGAAAAACCGTCCCGCAATCAAAACAGGCGATGTTGTGTACGCGAAAATGTTAAACGCAAGCAAAGATATGGAACCAGAGCTTGTGTGCGTTGATTCGCATGGAAAAAAAGGCCGACTAGGAGTATTAGAAGAAGGATTCGTATTCAAATGCTCTTTGAATTTAATCAGAAAAATATTAAACCCACATTGTCCATTATTGAACTCATTAAAGAACGAATGGCCATTTGAATTAGCAGCTGGCATGAATGGAAGGATTTGGATCAAAGCAAACACTATGAGAGAGACATTGGCTCTAGGAAACGCGATTTTGGGCTCAGAATATTTGAGTAACGATGAAATTAAAAGTATGTGTAAGAACATAGCAGTTTTACTCGCAGGTCATGTAAGCTAA

Protein

MNVSIDDVVLPGDHCPEIVAAGEKGKVLLGPGLRKEINGVFITKPGVLRKRTPNTYWVDNYQKRYVPSRGENVIGTVVQKAGDIFRVDVGGSCAASLSYLSFEGATKKNRPAIKTGDVVYAKMLNASKDMEPELVCVDSHGKKGRLGVLEEGFVFKCSLNLIRKILNPHCPLLNSLKNEWPFELAAGMNGRIWIKANTMRETLALGNAILGSEYLSNDEIKSMCKNIAVLLAGHVS

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Uniprot

C0LLE3   H9JK42   A0A2A4JSQ1   A0A2H1WJT5   A0A1E1W4A2   A0A212ER29   + More
A0A194PSL2   A0A0N0PAJ9   S4PFP9   A0A0L7L6P5   A0A1Q3F014   Q16G72   Q16K74   A0A1S4FYJ0   F4WJ75   A0A310SXH1   A0A195BW57   A0A158NED6   A0A182H5M8   A0A023EKX1   A0A1I8NYF3   B0XBU3   A0A151J6V5   A0A0L7RIW6   A0A195FKZ0   A0A195CC99   A0A2P8Z9Z6   A0A154PN51   A0A1I8MKK6   U5ERV0   A0A084W5J6   E9II57   E2BHM7   A0A0C9R0X5   A0A026W601   A0A182SYP3   E0VTU6   A0A2J7QP20   A0A182YHF8   E1ZVC2   Q7PJS3   A0A182VSV3   A0A0K8US84   A0A2M4AWE0   W5J647   W8BJ66   A0A034VQU8   A0A2M4BYL9   A0A3L8E2C3   A0A1A9WZZ3   A0A2A3EQ83   A0A088AVI6   A0A182N8T6   A0A0L0C477   A0A2P8Z9X4   A0A2T7NS46   A0A0J7KY24   K7IQ29   A0A2M3ZK25   A0A0M8ZS82   A0A182RAC0   A0A182FMX8   A0A232EQY9   A0A210PEF2   A0A1W4V1K4   B4NLT2   A0A1S3K1H3   A0A3S0ZRN1   A0A0M4E9X1   B4N7J0   B4KKU2   A0A1B6FJC5   T1DPP4   B3MKE8   B4LVK2   B4G7R6   Q29LQ3   B4P3L0   B4JZ82   A0A3B0JV57   A0A1B6IFT7   B4Q768   B3N8X2   B4IDB5   K1PH06   D0QWH8   Q8IPX7   W4YG77   T1H7D2   R7VC84   A0A2C9JNF1   A0A1B6CL21   A0A0B7AMN4   A0A1B6LDT9   A0A3P9ANC2   A0A1L8DXS3   A0A2G8LDG0   A0A1B0FIR4   A0A1B0AJN5   A0A1A9Y777  

Pubmed

19121390    22118469    26354079    23622113    26227816    17510324    + More
17519023    21719571    21347285    26483478    24945155    29403074    25315136    24438588    21282665    20798317    24508170    20566863    25244985    12364791    14747013    17210077    20920257    23761445    24495485    25348373    30249741    26108605    20075255    28648823    28812685    17994087    15632085    17550304    22936249    22992520    19859648    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    23254933    15562597    25069045    29023486   

EMBL

FJ715951    ACN65392.1    BABH01026639    NWSH01000644    PCG75067.1    PCG75068.1    + More
ODYU01009117    SOQ53309.1    GDQN01009247    JAT81807.1    AGBW02013148    OWR43935.1    KQ459595    KPI95749.1    KQ461192    KPJ07041.1    GAIX01006480    JAA86080.1    JTDY01002600    KOB71127.1    GFDL01014166    JAV20879.1    CH478320    EAT33241.1    EF173370    CH477974    ABM68596.1    EAT34692.1    GL888182    EGI65653.1    KQ759817    OAD62776.1    KQ976401    KYM92515.1    ADTU01013259    JXUM01112104    KQ565562    KXJ70881.1    GAPW01003776    JAC09822.1    DS232653    EDS44472.1    KQ979851    KYN18856.1    KQ414582    KOC70887.1    KQ981490    KYN41083.1    KQ978023    KYM97861.1    PYGN01000132    PSN53314.1    KQ434998    KZC13273.1    GANO01003551    JAB56320.1    ATLV01020668    KE525304    KFB45490.1    GL763358    EFZ19744.1    GL448317    EFN84811.1    GBYB01006567    JAG76334.1    KK107388    EZA51495.1    AAZO01005348    DS235773    EEB16802.1    NEVH01012097    PNF30332.1    GL434492    EFN74832.1    AAAB01008980    EAA43646.3    GDHF01022755    JAI29559.1    GGFK01011754    MBW45075.1    ADMH02002079    ETN59456.1    GAMC01016916    JAB89639.1    GAKP01014787    GAKP01014785    JAC44165.1    GGFJ01008971    MBW58112.1    QOIP01000001    RLU26827.1    KZ288198    PBC33664.1    JRES01000934    KNC27090.1    PSN53303.1    PZQS01000010    PVD23963.1    LBMM01002134    KMQ95221.1    GGFM01008069    MBW28820.1    KQ435922    KOX68469.1    NNAY01002718    OXU20696.1    NEDP02076749    OWF34836.1    CH964274    EDW85321.1    RQTK01000212    RUS84246.1    CP012523    ALC40027.1    CH964205    EDW80329.1    CH933807    EDW11672.1    GECZ01019676    JAS50093.1    GAMD01001755    JAA99835.1    CH902620    EDV32532.1    CH940649    EDW64396.1    CH479180    EDW29337.1    CH379060    EAL33992.1    CM000157    EDW87277.1    CH916379    EDV94191.1    OUUW01000004    SPP79360.1    GECU01021933    JAS85773.1    CM000361    CM002910    EDX03359.1    KMY87512.1    CH954177    EDV57372.1    CH480829    EDW45541.1    JH816681    EKC18159.1    FJ821029    ACN94677.1    AE014134    BT023807    AAN10459.1    AAZ66314.1    AHN54080.1    AAGJ04033754    AAGJ04033755    AMQN01017546    KB293238    ELU16219.1    GEDC01029568    GEDC01023134    GEDC01019986    JAS07730.1    JAS14164.1    JAS17312.1    HACG01034330    CEK81195.1    GEBQ01029435    GEBQ01018130    GEBQ01013823    GEBQ01010643    GEBQ01007535    JAT10542.1    JAT21847.1    JAT26154.1    JAT29334.1    JAT32442.1    GFDF01002836    JAV11248.1    MRZV01001826    MRZV01000118    PIK35731.1    PIK58245.1    CCAG010016357   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000037510    + More
UP000008820    UP000007755    UP000078540    UP000005205    UP000069940    UP000249989    UP000095300    UP000002320    UP000078492    UP000053825    UP000078541    UP000078542    UP000245037    UP000076502    UP000095301    UP000030765    UP000008237    UP000053097    UP000075901    UP000009046    UP000235965    UP000076408    UP000000311    UP000007062    UP000075920    UP000000673    UP000279307    UP000091820    UP000242457    UP000005203    UP000075884    UP000037069    UP000245119    UP000036403    UP000002358    UP000053105    UP000075900    UP000069272    UP000215335    UP000242188    UP000192221    UP000007798    UP000085678    UP000271974    UP000092553    UP000009192    UP000007801    UP000008792    UP000008744    UP000001819    UP000002282    UP000001070    UP000268350    UP000000304    UP000008711    UP000001292    UP000005408    UP000000803    UP000007110    UP000015102    UP000014760    UP000076420    UP000265140    UP000230750    UP000092444    UP000092445    UP000092443   

PRIDE

C0LLE3    H9JK42    Q8IPX7   

Pfam

PF15985   KH_6        + More
PF18311   Rrp40_N
PF00561   Abhydrolase_1
PF00106   adh_short

Interpro

IPR037319   Rrp40_S1        + More
IPR012340   NA-bd_OB-fold       
IPR036612   KH_dom_type_1_sf       
IPR026699   Exosome_RNA_bind1/RRP40/RRP4       
IPR004088   KH_dom_type_1       
IPR041054   Rrp40_N       
IPR029058   AB_hydrolase       
IPR000073   AB_hydrolase_1       
IPR002347   SDR_fam       
IPR020904   Sc_DH/Rdtase_CS       
IPR036291   NAD(P)-bd_dom_sf       

SUPFAM

SSF50249   SSF50249        + More
SSF54791   SSF54791       
SSF53474   SSF53474       
SSF51735   SSF51735       

Gene 3D

3.30.1370.10     3.40.50.1820    

CDD

cd05790  S1_Rrp40

ProteinModelPortal

C0LLE3   H9JK42   A0A2A4JSQ1   A0A2H1WJT5   A0A1E1W4A2   A0A212ER29   + More
A0A194PSL2   A0A0N0PAJ9   S4PFP9   A0A0L7L6P5   A0A1Q3F014   Q16G72   Q16K74   A0A1S4FYJ0   F4WJ75   A0A310SXH1   A0A195BW57   A0A158NED6   A0A182H5M8   A0A023EKX1   A0A1I8NYF3   B0XBU3   A0A151J6V5   A0A0L7RIW6   A0A195FKZ0   A0A195CC99   A0A2P8Z9Z6   A0A154PN51   A0A1I8MKK6   U5ERV0   A0A084W5J6   E9II57   E2BHM7   A0A0C9R0X5   A0A026W601   A0A182SYP3   E0VTU6   A0A2J7QP20   A0A182YHF8   E1ZVC2   Q7PJS3   A0A182VSV3   A0A0K8US84   A0A2M4AWE0   W5J647   W8BJ66   A0A034VQU8   A0A2M4BYL9   A0A3L8E2C3   A0A1A9WZZ3   A0A2A3EQ83   A0A088AVI6   A0A182N8T6   A0A0L0C477   A0A2P8Z9X4   A0A2T7NS46   A0A0J7KY24   K7IQ29   A0A2M3ZK25   A0A0M8ZS82   A0A182RAC0   A0A182FMX8   A0A232EQY9   A0A210PEF2   A0A1W4V1K4   B4NLT2   A0A1S3K1H3   A0A3S0ZRN1   A0A0M4E9X1   B4N7J0   B4KKU2   A0A1B6FJC5   T1DPP4   B3MKE8   B4LVK2   B4G7R6   Q29LQ3   B4P3L0   B4JZ82   A0A3B0JV57   A0A1B6IFT7   B4Q768   B3N8X2   B4IDB5   K1PH06   D0QWH8   Q8IPX7   W4YG77   T1H7D2   R7VC84   A0A2C9JNF1   A0A1B6CL21   A0A0B7AMN4   A0A1B6LDT9   A0A3P9ANC2   A0A1L8DXS3   A0A2G8LDG0   A0A1B0FIR4   A0A1B0AJN5   A0A1A9Y777  

PDB

6H25     E-value=3.30518e-56,     Score=550

KEGG

100301502    K03681 exosome complex component RRP40 | (RefSeq) Rrp40; exosome complex exonuclease Rrp40

PATHWAY

03018    RNA degradation - Bombyx mori (domestic silkworm)

GO

GO:0003723   GO:0000178   GO:0004527   GO:0000176   GO:0071034   GO:0034475   GO:0000177   GO:0071049   GO:0071038   GO:0034427   GO:0000467   GO:0043928   GO:0071051   GO:0071035   GO:0016491   GO:0010468   GO:0035167   GO:0005737   GO:0016021   GO:0005730   GO:0042254   GO:0004672   GO:0005524   GO:0006468   GO:0006032   GO:0005515   GO:0016742   GO:0003824  

PANTHER

PTHR21321  

Length:

236

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01379

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03709

outside

1  -  236

 

 

Pi

28.673439

Theta

26.539044

Tajima's D

0.2481

CLR

3.801213

CSRT

0.445527723613819

Interpretation

Uncertain