SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO04756  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA009883
Annotation
cyclin_dependent_kinase_12_[Bombyx_mori]
Location
Bomo_Chr8(+):14210164-14224876      View in EpiBrowser
Location in the cell
Nuclear   Reliability : 4.379
 

Sequence

CDS
ATGGAGCGCAGCTACGATAAGAAACATTCTAAACATCACAAGGACAAGCACAAGAAACGAGGTCACAAGAAACACAGGAGCTCAAGCGCATCGAGGAAACGTCACGCACACGAGTATGAACCTGAGAATTACGACGACCTCTCAAGGTTCAAAAAGAAAAAGGATAAACGTAAGAAGGAGAAAAAGAAAAGGAAGAAGAAGTCCAAACATCGGTCAAGGTCTGCAAGCTTAGAAAGCGTATCGCCGGATGATAACGTGCCAGAGGTGATTCCGGCGAGGCCAGCAACTCCGCAGCGGTATACGCGAGTGCCTATAAGCGAATGGGAAAAGCCCTCTTCTCCTTTAAGAAATGGCTCCTGTTCTCCTGTGTCGCCTACGACGCCACCGCTTCTGCGCCACGAACCGTCGCCAAGGCATCGCATAACGCATTCTCTTCATCATAATATAATTTCCTACTCACCTCGAGAAAACAGATCTCCTGTTAGGCGACGTCAGAAATCCACGACGCCACACACACCGGTGGCACCGCCTTATCAAGAGCCAGTGACCATAGACTCTGACACCGAGCAGGACTATGAGCGGGGACGTCGAGAATATTGGCACGAGCAGCGAATACCACAGTCGCCCATTATGGTCTCTGACTCTCCGGTGCGCGAGTGTCGGTCCCGCGAGTACAGTCCGCGCCGCCACCGCCGCCGCACGCCGCGCCGCCGCCACCGCAGCCGCGAGCGACATCACGTCCGGACCATACACAGATCACACAGTCGCAGTTCGTTGAAGCGGCGCCGCTCGGTGTCTCGCGGGCGCCGGCGGGACGACACCGCCTCCCCGCCGCGACACCGCGCCCGACACCGGGACCCCTCGCGGGACAGACACCGTACCAGGCACGACTCGCCCAGTCCACCTGCGACTTTACAGAGGAGAATAGACTTTAAGGAAAAGATCAGCGATACCAGTTTATTTGCTGAATTAGTTAAGGACAAGCACAAGAGAGCAAAGAAGTTACAAGAAATATTGAACCAAAAGGAGGAAGAGTCTCAAGGTGCAGCGTCAACGGTCACGTCAAATAACCAGGACGTGGTTACCATCGACGAGCTATCCAACAATACCTCTGACAGTCTGTTAAAACCGACGTTGAAAGAAAATGGTGAGGTACCAAAAGAAGTTACGGAAGTGGTCGTCAGCGACGCCCCCGGGATGCTTCAAGGCATCCCCCCGCCGCCGCCCGCCGCTTCGCCCCCCGCACTCCCTTCGCCGCCACCCGCCGCCAACGGAGAACAAACGCTCGTTGATCAGAAGATACCCCTTCCTGCGCCGGTGCCGCCCCCGAAGACGAGCAGCGTGGTAGAGGGAGTGTTCCTAAACAATCAACAACCGGCGCCTAAACATAAGAGCCTCACCAAGCTGCCCATGCCGCCAAACACACAGGTTGAAGACTTAAAAACGTTGGTGAACGAAAGTCCATTAAGTACGCCTTCACCTAGCCCTGTGAAAAAGCCAGAAAAACCCAAGAGAACTGGCATTATGAATTTGCCTATGCCACCTGTGATAACTAGTGCTACAGACGAGCTGAGTGGAGACGAGCTGGACGGGTCCACACCGCCGCCTGCCTCGCGACACGAACAATACTCGCATGTCTTTAGTTCAAAGAAAAGCAATAAAGATTCGAGTTCGAAACTCAAGAGGCCAAAAATATTAAAGCGAAGAGGTTCCAAGATTGTTCCTGTGGCGACGCCCACGCACCACGCCAAAGACTGGGGGGAAAAATGCGTTGATGGCTTCCAGGTGCTGACACAAATTGGGGAAGGAACATATGGACAAGTTTACAAAGCCAAAGATAAGAACACAGGTCAGTTGGTAGCTTTGAAGAAAGTTCGCCTCGAAAACGAAAAGGAGGGCTTCCCGATCACGGCTGTGAGAGAAATCAAGATTTTAAGGCAATTGAATCACAAGAACATTGTCAATTTACGAGAAATTGTGACTGACAAACAGGATGCTATGGACTTCAGAAAGGATAAAGGCTCATTCTATTTGGTCTTTGAATACATGGACCACGATCTTATGGGTCTTTTGGAGTCAAAAATGGTGGATTTCACAGAGTCTCACAATGCATCTATAATGAGGCAATTGCTGGATGGATTAGCGTACTGTCATCGGAAGAATTTCTTACATAGAGATATTAAATGCAGTAATATACTCATGAATAACAGAGGCGAAGTGAAGCTGGGCGACTTTGGTTTGGCTCGACTGTGGCAGGCGGAGGACAGAGAGAGACCCTACACTAACAAGGTGATAACTTTGTGGTACCGACCACCTGAACTGCTGCTCGGGGAGGAGCGGTATGGACCTGCAGTAGACGTCTGGTCTATGGGCTGTATCCTTGGAGAACTGTTCCTCAAACATCCGCTCTTCCAGGCGAGTGTAGAGATGATGCAGTTGGAAATGATATCCCGGACGTGCGGTACTCCTGTACCGGGAGTGTGGCCTAATGTAGTGAATCTCCCACTGTGGCACACTCTTAGACCCAAACGGTTCCACAAGCGATGTGTTCGGGAACAATTCGCTTTCATGCCCACTCCAGCACTCAACCTGCTCGACAGGATGCTGGAATTGGATCCGGAAAAAAGGATCACCGCAGAAGAGTCGTTGAAGAGTCCTTGGCTTAAGAATATTGTGCCAGATCAAATGCCTCCGCCGGAGCTACCCACGTGGCAGGACTGTCACGAGCTGTGGTCGAAACAGCGGCGCAGGCAACAGAGGGAAGAACAACAAGGAAAGAAGCCTTACTTCTCGGAAGACAGCAAGTCCAATGATCAGACTGATTTCAAAACAGACGGATTCAAACCGTCTGAGCCTCCGCCCGATGTTGTTGGACAAGTGAAATAG
Protein
MERSYDKKHSKHHKDKHKKRGHKKHRSSSASRKRHAHEYEPENYDDLSRFKKKKDKRKKEKKKRKKKSKHRSRSASLESVSPDDNVPEVIPARPATPQRYTRVPISEWEKPSSPLRNGSCSPVSPTTPPLLRHEPSPRHRITHSLHHNIISYSPRENRSPVRRRQKSTTPHTPVAPPYQEPVTIDSDTEQDYERGRREYWHEQRIPQSPIMVSDSPVRECRSREYSPRRHRRRTPRRRHRSRERHHVRTIHRSHSRSSLKRRRSVSRGRRRDDTASPPRHRARHRDPSRDRHRTRHDSPSPPATLQRRIDFKEKISDTSLFAELVKDKHKRAKKLQEILNQKEEESQGAASTVTSNNQDVVTIDELSNNTSDSLLKPTLKENGEVPKEVTEVVVSDAPGMLQGIPPPPPAASPPALPSPPPAANGEQTLVDQKIPLPAPVPPPKTSSVVEGVFLNNQQPAPKHKSLTKLPMPPNTQVEDLKTLVNESPLSTPSPSPVKKPEKPKRTGIMNLPMPPVITSATDELSGDELDGSTPPPASRHEQYSHVFSSKKSNKDSSSKLKRPKILKRRGSKIVPVATPTHHAKDWGEKCVDGFQVLTQIGEGTYGQVYKAKDKNTGQLVALKKVRLENEKEGFPITAVREIKILRQLNHKNIVNLREIVTDKQDAMDFRKDKGSFYLVFEYMDHDLMGLLESKMVDFTESHNASIMRQLLDGLAYCHRKNFLHRDIKCSNILMNNRGEVKLGDFGLARLWQAEDRERPYTNKVITLWYRPPELLLGEERYGPAVDVWSMGCILGELFLKHPLFQASVEMMQLEMISRTCGTPVPGVWPNVVNLPLWHTLRPKRFHKRCVREQFAFMPTPALNLLDRMLELDPEKRITAEESLKSPWLKNIVPDQMPPPELPTWQDCHELWSKQRRRQQREEQQGKKPYFSEDSKSNDQTDFKTDGFKPSEPPPDVVGQVK

Summary

Uniprot
H6VMF5   H6VMF6   H9JK32   A0A212FEE2   A0A1Y1JVZ4   A0A1Y1K0S3   + More
A0A1Y1JZD1  
Pubmed
19121390    22118469    28004739   
EMBL
JN833623    AFB82434.1    JN833624    AFB82435.1    BABH01026597    BABH01026598    + More
AGBW02008940    OWR52119.1    GEZM01101719    JAV52368.1    GEZM01101720    JAV52367.1    GEZM01101721    JAV52366.1   
Proteomes
UP000005204    UP000007151   
PRIDE
H6VMF5    H6VMF6    H9JK32   
Pfam
PF00069   Pkinase
Interpro
IPR000719   Prot_kinase_dom        + More
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       
IPR017441   Protein_kinase_ATP_BS       
SUPFAM
SSF56112   SSF56112       
ProteinModelPortal
H6VMF5   H6VMF6   H9JK32   A0A212FEE2   A0A1Y1JVZ4   A0A1Y1K0S3   + More
A0A1Y1JZD1  
PDB
5EFQ     E-value=8.61948e-145,     Score=1320

Ontologies

KEGG
100884167    K08819 cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23] | (RefSeq) CDK12; cyclin dependent kin
GO
GO:0004672   GO:0005524   GO:0006468   GO:0017048   GO:0030036   GO:0016020   GO:0035023   GO:0005515   GO:0016742   GO:0003824  

Topology

Length:
961
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.01565
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00004
outside
1  -  961
 
 

Population Genetic Test Statistics

Pi
220.005572
Theta
170.924362
Tajima's D
1.19178
CLR
0.11299
CSRT
0.709364531773411
Interpretation
Uncertain
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