Gene
KWMTBOMO04741 Validated by peptides from experiments
Pre Gene Modal
BGIBMGA009875
Annotation
PREDICTED:_probable_dynactin_subunit_2_[Plutella_xylostella]
Full name
Dynactin subunit 2
Alternative Name
Dynactin 2 p50 subunit
Location in the cell
Cytoplasmic Reliability : 2.073 Nuclear Reliability : 1.665
Sequence
CDS
ATGGCTGATCCTAAATATGAAAATCTACCCGGCATTGCCTATGACCAACGCGATGTTTATGAAACTGATGATCTTCCGGAAGCCGATCAGCCGGAGCCTTATGAGGAGGAGGAGAACGAGTGTATCGAACAATTGCACTTATCGGTCAAGGATTCTTTCAATAAATTCAAAGGGAAGTTCCTTACTGGCCCTGTAGATTTTTCAGATAAATTGAGCAGAAAATCTCGAATTGGTTACAGAGTTGGTGAATGGGAGCTAGCAGCTGAAGGTGACCCGGAGACTCCACTACAAAGATACAATAGACTTAGATGTGAGTTTTCTGAACTCCTCGAAGATGTCACTGACCAACAAAACAAAGCTGGCGATAGTGAAAAGGAAGAGTTCTCCAAGTTGGCCGTACAAATCAACACAACGAAGAAACTTCTGGAAGAATTGAAACTTGAAGAAGGAGAACAAATTGACCCTAAGGCCGAGAAACTAAAGGAGTACCTGTCGTCGAACGGCAGGAAGAAGCAGGGTGAGCTGATCACGGCGCAGCTGAAGTTGAAGCCTGAAATAAGCCTCGCGCAGACCACAAGGGTTGCTCAACTCGAGCACAGATTACACAAATTAGAGCAGGCTGCCGGCGTGAGGGATGAGGAGGCGTTCCGACGACTCCAAGCTGCCACTGGACAGGCGACGCTGGCGGGCGCAGCGTGTCGTCTGGCGGCGCAGGCGGGCGCGCTGCGGGCGGGCGAGGTGGCGGCGGCGGACGCGCGGGTGGGTGCGCTGCTGGCCAACGTGCACGCGCTCCGGGCCGCACTCACGCCCGCCGACCCGCAACTCGATGAGAAGGTTAACGAATTGTACAAATTGGTGAAGCAAATTGAAGGCATTTCACATTCGGAAATAATTGAAAGGATGGAAGCGCTAGAGGCTCTGCATCATCAAGCCAGTAACTTCGGGAAGTCGCTGACTGAGCTCGAGTCGCTGCAGAGCAGCATCGCGGGCGGCGTCCACAAGAACCGGGAGCTCCTGCAGAGCGTCCAAGAAGTGTTCGCGCTGAACGTGAACAGCCTCAACAAGGAGATACGGAAACTGGACGAGAGGATCTCGAAATTGGCGCAGGCTTCGTAA
Protein
MADPKYENLPGIAYDQRDVYETDDLPEADQPEPYEEEENECIEQLHLSVKDSFNKFKGKFLTGPVDFSDKLSRKSRIGYRVGEWELAAEGDPETPLQRYNRLRCEFSELLEDVTDQQNKAGDSEKEEFSKLAVQINTTKKLLEELKLEEGEQIDPKAEKLKEYLSSNGRKKQGELITAQLKLKPEISLAQTTRVAQLEHRLHKLEQAAGVRDEEAFRRLQAATGQATLAGAACRLAAQAGALRAGEVAAADARVGALLANVHALRAALTPADPQLDEKVNELYKLVKQIEGISHSEIIERMEALEALHHQASNFGKSLTELESLQSSIAGGVHKNRELLQSVQEVFALNVNSLNKEIRKLDERISKLAQAS
Summary
Description
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis.
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity).
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity).
Subunit
Subunit of dynactin, a multiprotein complex associated with dynein.
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
Similarity
Belongs to the dynactin subunit 2 family.
Belongs to the CAMSAP1 family.
Belongs to the histone H2A family.
Belongs to the histone H3 family.
Belongs to the CAMSAP1 family.
Belongs to the histone H2A family.
Belongs to the histone H3 family.
Keywords
Coiled coil
Complete proteome
Cytoplasm
Cytoskeleton
Dynein
Membrane
Microtubule
Reference proteome
Phosphoprotein
Feature
chain Dynactin subunit 2
Uniprot
H9JK24
A0A2A4J974
A0A2H1W8L2
A0A3S2MB12
A0A212EZ38
A0A194PRY5
+ More
A0A0N0PEG8 A0A0A1WRU2 A0A0A1WUB2 A0A1I8NP86 W8BRQ0 A0A182YJE0 T1PFB3 A0A1B0GKJ6 A0A336N1D7 A0A0K8U9P5 A0A034VW84 A0A336MXZ2 A0A1L8E5B3 A0A182JEM7 A0A182R4D3 B0WG66 A0A182LTT0 A0A0L0CIH8 A0A182WEH2 A0A182PC76 A0A182JWL3 A0A0K8TMC0 A0A1B0DJR6 U5EW30 A0A182QJW7 A0A182N2I6 Q1HQF2 A0A023ER49 A0A2M4CTK7 A0A1W4W8B9 A0A084VIG6 A0A2M4BRR9 A0A2M4AJR5 A0A2M4AKR2 T1DQ27 A0A182FUU2 A0A182L4E1 Q7PZ25 A0A151XBY7 A0A2M4CTN3 A0A1Q3FDZ8 F4X6G9 A0A182HGZ3 A0A182XKN7 A0A182TL55 A0A195F0W6 A0A2M3Z598 A0A158NFZ5 A0A195E748 A0A1A9XPL6 A0A1B0BDU0 A0A2J7R7A4 A0A154PCN4 A0A1L8E4Z7 A0A1A9WWN9 A0A2A3EQ21 A0A0J7KRX4 A0A0L7QYY8 A0A1A9Z4F8 A0A088ACJ2 A0A3B0J635 B4JVD9 A0A026X2U5 D3TM53 A0A1A9UHE6 B4GGJ2 A0A0N0BE58 Q28Y46 B4KTR4 A0A0M5J2A1 B4LN94 A0A1W4UKV5 B4P3D1 B3MFD9 A0A0C9QUY4 J3JXD9 B3N856 B4QG96 Q7K2D2 A0A067RTM8 B4HSA2 A0A1Y1KD65 E2AM04 B4MK51 A0A182V8C5 A0A0A9XLW3 A0A146LAN6 A0A1B6EH75 A0A1B0FGT9
A0A0N0PEG8 A0A0A1WRU2 A0A0A1WUB2 A0A1I8NP86 W8BRQ0 A0A182YJE0 T1PFB3 A0A1B0GKJ6 A0A336N1D7 A0A0K8U9P5 A0A034VW84 A0A336MXZ2 A0A1L8E5B3 A0A182JEM7 A0A182R4D3 B0WG66 A0A182LTT0 A0A0L0CIH8 A0A182WEH2 A0A182PC76 A0A182JWL3 A0A0K8TMC0 A0A1B0DJR6 U5EW30 A0A182QJW7 A0A182N2I6 Q1HQF2 A0A023ER49 A0A2M4CTK7 A0A1W4W8B9 A0A084VIG6 A0A2M4BRR9 A0A2M4AJR5 A0A2M4AKR2 T1DQ27 A0A182FUU2 A0A182L4E1 Q7PZ25 A0A151XBY7 A0A2M4CTN3 A0A1Q3FDZ8 F4X6G9 A0A182HGZ3 A0A182XKN7 A0A182TL55 A0A195F0W6 A0A2M3Z598 A0A158NFZ5 A0A195E748 A0A1A9XPL6 A0A1B0BDU0 A0A2J7R7A4 A0A154PCN4 A0A1L8E4Z7 A0A1A9WWN9 A0A2A3EQ21 A0A0J7KRX4 A0A0L7QYY8 A0A1A9Z4F8 A0A088ACJ2 A0A3B0J635 B4JVD9 A0A026X2U5 D3TM53 A0A1A9UHE6 B4GGJ2 A0A0N0BE58 Q28Y46 B4KTR4 A0A0M5J2A1 B4LN94 A0A1W4UKV5 B4P3D1 B3MFD9 A0A0C9QUY4 J3JXD9 B3N856 B4QG96 Q7K2D2 A0A067RTM8 B4HSA2 A0A1Y1KD65 E2AM04 B4MK51 A0A182V8C5 A0A0A9XLW3 A0A146LAN6 A0A1B6EH75 A0A1B0FGT9
Pubmed
19121390
22118469
26354079
25830018
24495485
25244985
+ More
25315136 25348373 26108605 26369729 17204158 17510324 24945155 26483478 24438588 20966253 12364791 21719571 21347285 17994087 24508170 30249741 20353571 15632085 17550304 22516182 23537049 22936249 10731132 12537572 12537569 18327897 24845553 28004739 20798317 25401762 26823975
25315136 25348373 26108605 26369729 17204158 17510324 24945155 26483478 24438588 20966253 12364791 21719571 21347285 17994087 24508170 30249741 20353571 15632085 17550304 22516182 23537049 22936249 10731132 12537572 12537569 18327897 24845553 28004739 20798317 25401762 26823975
EMBL
BABH01026574
BABH01026575
NWSH01002387
PCG68409.1
ODYU01007027
SOQ49408.1
+ More
RSAL01000001 RVE55141.1 AGBW02011376 OWR46765.1 KQ459595 KPI95718.1 KQ459784 KPJ19954.1 GBXI01013134 JAD01158.1 GBXI01011643 JAD02649.1 GAMC01004703 JAC01853.1 KA646855 AFP61484.1 AJWK01028990 AJWK01028991 UFQS01001890 UFQT01001890 SSX12655.1 SSX32098.1 GDHF01029239 JAI23075.1 GAKP01011351 JAC47601.1 UFQS01002706 UFQT01002706 SSX14571.1 SSX33969.1 GFDF01000275 JAV13809.1 DS231923 EDS26762.1 AXCM01000823 JRES01000335 KNC32213.1 GDAI01002104 JAI15499.1 AJVK01001036 GANO01001618 JAB58253.1 AXCN02001076 DQ440492 CH477371 ABF18525.1 EAT42431.1 JXUM01072472 GAPW01001985 KQ562722 JAC11613.1 KXJ75253.1 GGFL01004504 MBW68682.1 ATLV01013356 KE524854 KFB37760.1 GGFJ01006337 MBW55478.1 GGFK01007709 MBW41030.1 GGFK01007887 MBW41208.1 GAMD01002824 JAA98766.1 AAAB01008986 EAA00075.3 KQ982314 KYQ57874.1 GGFL01004505 MBW68683.1 GFDL01009264 JAV25781.1 GL888818 EGI57929.1 APCN01002368 KQ981864 KYN34220.1 GGFM01002932 MBW23683.1 ADTU01014868 KQ979568 KYN20921.1 JXJN01012678 NEVH01006738 PNF36714.1 KQ434874 KZC09689.1 GFDF01000281 JAV13803.1 KZ288204 PBC33229.1 LBMM01003913 KMQ92999.1 KQ414685 KOC63803.1 OUUW01000001 SPP75202.1 CH916375 EDV98407.1 KK107020 QOIP01000004 EZA62423.1 RLU23428.1 EZ422505 ADD18781.1 CH479183 EDW35612.1 KQ435840 KOX71404.1 CM000071 CH933808 EDW09647.1 CP012524 ALC40648.1 CH940648 EDW60098.1 CM000157 EDW89404.1 CH902619 EDV35613.1 GBYB01007569 JAG77336.1 APGK01058017 BT127908 KB741285 KB632425 AEE62870.1 ENN70750.1 ERL95359.1 CH954177 EDV59469.1 CM000362 CM002911 EDX06246.1 KMY92355.1 AE013599 AY061092 KK852470 KDR23199.1 CH480816 EDW46997.1 GEZM01087851 JAV58438.1 GL440703 EFN65524.1 CH963846 EDW72490.1 GBHO01023791 GBRD01006568 JAG19813.1 JAG59253.1 GDHC01013176 JAQ05453.1 GEDC01000074 JAS37224.1 CCAG010018052
RSAL01000001 RVE55141.1 AGBW02011376 OWR46765.1 KQ459595 KPI95718.1 KQ459784 KPJ19954.1 GBXI01013134 JAD01158.1 GBXI01011643 JAD02649.1 GAMC01004703 JAC01853.1 KA646855 AFP61484.1 AJWK01028990 AJWK01028991 UFQS01001890 UFQT01001890 SSX12655.1 SSX32098.1 GDHF01029239 JAI23075.1 GAKP01011351 JAC47601.1 UFQS01002706 UFQT01002706 SSX14571.1 SSX33969.1 GFDF01000275 JAV13809.1 DS231923 EDS26762.1 AXCM01000823 JRES01000335 KNC32213.1 GDAI01002104 JAI15499.1 AJVK01001036 GANO01001618 JAB58253.1 AXCN02001076 DQ440492 CH477371 ABF18525.1 EAT42431.1 JXUM01072472 GAPW01001985 KQ562722 JAC11613.1 KXJ75253.1 GGFL01004504 MBW68682.1 ATLV01013356 KE524854 KFB37760.1 GGFJ01006337 MBW55478.1 GGFK01007709 MBW41030.1 GGFK01007887 MBW41208.1 GAMD01002824 JAA98766.1 AAAB01008986 EAA00075.3 KQ982314 KYQ57874.1 GGFL01004505 MBW68683.1 GFDL01009264 JAV25781.1 GL888818 EGI57929.1 APCN01002368 KQ981864 KYN34220.1 GGFM01002932 MBW23683.1 ADTU01014868 KQ979568 KYN20921.1 JXJN01012678 NEVH01006738 PNF36714.1 KQ434874 KZC09689.1 GFDF01000281 JAV13803.1 KZ288204 PBC33229.1 LBMM01003913 KMQ92999.1 KQ414685 KOC63803.1 OUUW01000001 SPP75202.1 CH916375 EDV98407.1 KK107020 QOIP01000004 EZA62423.1 RLU23428.1 EZ422505 ADD18781.1 CH479183 EDW35612.1 KQ435840 KOX71404.1 CM000071 CH933808 EDW09647.1 CP012524 ALC40648.1 CH940648 EDW60098.1 CM000157 EDW89404.1 CH902619 EDV35613.1 GBYB01007569 JAG77336.1 APGK01058017 BT127908 KB741285 KB632425 AEE62870.1 ENN70750.1 ERL95359.1 CH954177 EDV59469.1 CM000362 CM002911 EDX06246.1 KMY92355.1 AE013599 AY061092 KK852470 KDR23199.1 CH480816 EDW46997.1 GEZM01087851 JAV58438.1 GL440703 EFN65524.1 CH963846 EDW72490.1 GBHO01023791 GBRD01006568 JAG19813.1 JAG59253.1 GDHC01013176 JAQ05453.1 GEDC01000074 JAS37224.1 CCAG010018052
Proteomes
UP000005204
UP000218220
UP000283053
UP000007151
UP000053268
UP000053240
+ More
UP000095300 UP000076408 UP000095301 UP000092461 UP000075880 UP000075900 UP000002320 UP000075883 UP000037069 UP000075920 UP000075885 UP000075881 UP000092462 UP000075886 UP000075884 UP000008820 UP000069940 UP000249989 UP000192223 UP000030765 UP000069272 UP000075882 UP000007062 UP000075809 UP000007755 UP000075840 UP000076407 UP000075902 UP000078541 UP000005205 UP000078492 UP000092443 UP000092460 UP000235965 UP000076502 UP000091820 UP000242457 UP000036403 UP000053825 UP000092445 UP000005203 UP000268350 UP000001070 UP000053097 UP000279307 UP000078200 UP000008744 UP000053105 UP000001819 UP000009192 UP000092553 UP000008792 UP000192221 UP000002282 UP000007801 UP000019118 UP000030742 UP000008711 UP000000304 UP000000803 UP000027135 UP000001292 UP000000311 UP000007798 UP000075903 UP000092444
UP000095300 UP000076408 UP000095301 UP000092461 UP000075880 UP000075900 UP000002320 UP000075883 UP000037069 UP000075920 UP000075885 UP000075881 UP000092462 UP000075886 UP000075884 UP000008820 UP000069940 UP000249989 UP000192223 UP000030765 UP000069272 UP000075882 UP000007062 UP000075809 UP000007755 UP000075840 UP000076407 UP000075902 UP000078541 UP000005205 UP000078492 UP000092443 UP000092460 UP000235965 UP000076502 UP000091820 UP000242457 UP000036403 UP000053825 UP000092445 UP000005203 UP000268350 UP000001070 UP000053097 UP000279307 UP000078200 UP000008744 UP000053105 UP000001819 UP000009192 UP000092553 UP000008792 UP000192221 UP000002282 UP000007801 UP000019118 UP000030742 UP000008711 UP000000304 UP000000803 UP000027135 UP000001292 UP000000311 UP000007798 UP000075903 UP000092444
PRIDE
Pfam
Interpro
IPR028133
Dynamitin
+ More
IPR022613 CAMSAP_CH
IPR032940 CAMSAP
IPR031372 CAMSAP_CC1
IPR011033 PRC_barrel-like_sf
IPR038209 CKK_dom_sf
IPR014797 CKK_domain
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR032458 Histone_H2A_CS
IPR002119 Histone_H2A
IPR002939 DnaJ_C
IPR000164 Histone_H3/CENP-A
IPR007125 Histone_H2A/H2B/H3
IPR032454 Histone_H2A_C
IPR009072 Histone-fold
IPR008971 HSP40/DnaJ_pept-bd
IPR022613 CAMSAP_CH
IPR032940 CAMSAP
IPR031372 CAMSAP_CC1
IPR011033 PRC_barrel-like_sf
IPR038209 CKK_dom_sf
IPR014797 CKK_domain
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR032458 Histone_H2A_CS
IPR002119 Histone_H2A
IPR002939 DnaJ_C
IPR000164 Histone_H3/CENP-A
IPR007125 Histone_H2A/H2B/H3
IPR032454 Histone_H2A_C
IPR009072 Histone-fold
IPR008971 HSP40/DnaJ_pept-bd
Gene 3D
CDD
ProteinModelPortal
H9JK24
A0A2A4J974
A0A2H1W8L2
A0A3S2MB12
A0A212EZ38
A0A194PRY5
+ More
A0A0N0PEG8 A0A0A1WRU2 A0A0A1WUB2 A0A1I8NP86 W8BRQ0 A0A182YJE0 T1PFB3 A0A1B0GKJ6 A0A336N1D7 A0A0K8U9P5 A0A034VW84 A0A336MXZ2 A0A1L8E5B3 A0A182JEM7 A0A182R4D3 B0WG66 A0A182LTT0 A0A0L0CIH8 A0A182WEH2 A0A182PC76 A0A182JWL3 A0A0K8TMC0 A0A1B0DJR6 U5EW30 A0A182QJW7 A0A182N2I6 Q1HQF2 A0A023ER49 A0A2M4CTK7 A0A1W4W8B9 A0A084VIG6 A0A2M4BRR9 A0A2M4AJR5 A0A2M4AKR2 T1DQ27 A0A182FUU2 A0A182L4E1 Q7PZ25 A0A151XBY7 A0A2M4CTN3 A0A1Q3FDZ8 F4X6G9 A0A182HGZ3 A0A182XKN7 A0A182TL55 A0A195F0W6 A0A2M3Z598 A0A158NFZ5 A0A195E748 A0A1A9XPL6 A0A1B0BDU0 A0A2J7R7A4 A0A154PCN4 A0A1L8E4Z7 A0A1A9WWN9 A0A2A3EQ21 A0A0J7KRX4 A0A0L7QYY8 A0A1A9Z4F8 A0A088ACJ2 A0A3B0J635 B4JVD9 A0A026X2U5 D3TM53 A0A1A9UHE6 B4GGJ2 A0A0N0BE58 Q28Y46 B4KTR4 A0A0M5J2A1 B4LN94 A0A1W4UKV5 B4P3D1 B3MFD9 A0A0C9QUY4 J3JXD9 B3N856 B4QG96 Q7K2D2 A0A067RTM8 B4HSA2 A0A1Y1KD65 E2AM04 B4MK51 A0A182V8C5 A0A0A9XLW3 A0A146LAN6 A0A1B6EH75 A0A1B0FGT9
A0A0N0PEG8 A0A0A1WRU2 A0A0A1WUB2 A0A1I8NP86 W8BRQ0 A0A182YJE0 T1PFB3 A0A1B0GKJ6 A0A336N1D7 A0A0K8U9P5 A0A034VW84 A0A336MXZ2 A0A1L8E5B3 A0A182JEM7 A0A182R4D3 B0WG66 A0A182LTT0 A0A0L0CIH8 A0A182WEH2 A0A182PC76 A0A182JWL3 A0A0K8TMC0 A0A1B0DJR6 U5EW30 A0A182QJW7 A0A182N2I6 Q1HQF2 A0A023ER49 A0A2M4CTK7 A0A1W4W8B9 A0A084VIG6 A0A2M4BRR9 A0A2M4AJR5 A0A2M4AKR2 T1DQ27 A0A182FUU2 A0A182L4E1 Q7PZ25 A0A151XBY7 A0A2M4CTN3 A0A1Q3FDZ8 F4X6G9 A0A182HGZ3 A0A182XKN7 A0A182TL55 A0A195F0W6 A0A2M3Z598 A0A158NFZ5 A0A195E748 A0A1A9XPL6 A0A1B0BDU0 A0A2J7R7A4 A0A154PCN4 A0A1L8E4Z7 A0A1A9WWN9 A0A2A3EQ21 A0A0J7KRX4 A0A0L7QYY8 A0A1A9Z4F8 A0A088ACJ2 A0A3B0J635 B4JVD9 A0A026X2U5 D3TM53 A0A1A9UHE6 B4GGJ2 A0A0N0BE58 Q28Y46 B4KTR4 A0A0M5J2A1 B4LN94 A0A1W4UKV5 B4P3D1 B3MFD9 A0A0C9QUY4 J3JXD9 B3N856 B4QG96 Q7K2D2 A0A067RTM8 B4HSA2 A0A1Y1KD65 E2AM04 B4MK51 A0A182V8C5 A0A0A9XLW3 A0A146LAN6 A0A1B6EH75 A0A1B0FGT9
PDB
6F38
E-value=2.29239e-07,
Score=131
Ontologies
GO
GO:0005869
GO:0007017
GO:0005737
GO:0030286
GO:0003774
GO:0005874
GO:0000278
GO:0031982
GO:0016020
GO:0008283
GO:0005813
GO:0007052
GO:0061883
GO:0016325
GO:0051642
GO:1904115
GO:0007602
GO:0045451
GO:0007051
GO:0051028
GO:2001019
GO:0008090
GO:0005938
GO:0048477
GO:0007018
GO:0008017
GO:0030507
GO:0005516
GO:0031175
GO:0005634
GO:0003677
GO:0000786
GO:0051082
GO:0006457
GO:0046982
Topology
Subcellular location
Cytoplasm
Cytoskeleton
Membrane
Chromosome
Nucleus
Cytoskeleton
Membrane
Chromosome
Nucleus
Length:
371
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.000760000000000001
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00702
outside
1 - 371
Population Genetic Test Statistics
Pi
320.501203
Theta
165.679864
Tajima's D
3.160688
CLR
0.199371
CSRT
0.984200789960502
Interpretation
Uncertain
