Gene

KWMTBOMO04735

Pre Gene Modal

BGIBMGA010465

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr8(+):13787010-13789941      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Nuclear   Reliability : 3.435

CDS

ATGGGAGAAGGCATAGAAGACCACGGAAAGTATATACTGCATTATAAAGGAGAAACACCAGGACAATACGGAGTTGGTTTTTTGATAAAAAGAAAATATATGGACCGAATCGAGGAATTGAAGGGCATATCCGAAAGAATAGCAATACTCAACATCAAATTTCCCGTACAAAATAGCAGAGACGAATTATGGTCAATTATTCAGGTTTACTCGCCAACTGAAGCAGATAAAAAACAAGACACAAACAAAATAGAGGAATTCTACCAAAAATTACAAAGTACTGTTGATACAGCTCACAAAAATTTAATAATAATGGGTGATTTTAATGGACAAATTGGGGAATGTCGTAGTGGCGAAGAGTACATTGTAGGAAGATATGGCAATGGCAATAGGAGCAAAAACGGACAACATTTGGTTAACTTCGGTTTAGAAAACAAACTAAGTATCTTGAATAGTTTCTTTAAAAAGAAAAAGAATAAGAAATGGACGTGGACCTCCCCAAATGGACTCTTTAAAAATGAAATCGACTACATTATGACCAATAAACCAAAAGTTTTTAAAGATCTATCAGTTTTACATAATTTAAATTTTAATTCGGACCATAAAATGATACGTGCAACGTTACGAGCGTCACATACAAAGAAAAGTCGAAGGCTGCAAACTGGATTGACTCCCTATGTGGACATTAAAAATAACTTAGAGATAATGAACAATTTAAAAGAATTTCTAGAGAGAAGAGAACAAAAGGAATACAATAAAACAATTGAGGCGACATACTGCTATTTTGTAAATACTCTCAAAACTGTTGCTCGAAAAGTGTCTACAAATAATAAATCCATACTATCTACCGAAACTATTATATTACTTAAAGAAAGAAAATTGCTTTTACAAGGCAATAAAGACAAAGAAACACGAAAAGAGATCGCAGAAATAAGTAAAAATATCAACAAAAATATCAGGAAAGACAGAAAACAAAAAAGGGCAAATACTTTCCAATATCATATTAAGAAAACAGGCGGAGTGAAGAAAACGTTTAAAGAACTAGAATCGAAAAAGAATTGGATGCCAAATATTAAGGACAGACAAGGAAGAAGTAATACAAAAAGATCAGAAATATTAAATATTGCTACGCAATACTATAAGGAGTTGTACACAAGCAAAAATGAAAAACCTGCCACGACTACGACAGAAGACATGCAAGATATTGAACCTATACCACCTATTCTAAAAGAAGAAACAGAAAGAGCTATCACTACGCAGAAGTTAGGAAAAGCGCCCGGTCTTGATCAAATTACCAATGAACTTCTCAAAACATTCATGCCGGCAATAGTCCCTAAACTAACCAATTTGTTTAACGAAATAATAACAGCAGAAGTCATCCCAGAAGACTGGGTGAGATCAGTGATAGTTTTGTTGCACAAAAAAGGAGACAAAAGAGACATTAACAATTATAGGCCAATAAGCTTAATGTCTAATATATACAAGATCTTTTCTAAAATACTATTGTTTAGACTAACTATTACCCTTGACGAAAACCAGCCAAAAGAGCAAGCTGGATTTAGGAGCAATTTCTCGACCATTGATCACATACACGTCCTACGCCAGATACTTCAGAAATATAGAGAATACAACAAAACATATTATTTGGGTTTTGTAGATTTCAACAAGGCGTTTGATTCCTTGGAACACCACTACATATGGGAATCATTAGAACAACAAGGGGTCCATAAAAAGTACATACGTATCCTAAAAAATATTTATGGGAAAAGCACAGCACAAATAAAACTTGAAAAATTAGGTGAAGAGTTCCCAATAGAAAGAGGCGTCCGTCAAGGTGATCCTATTTCGCCGAAAATATTCTCAGCAGTGTTGGAGTTGATCTTTAGGAAACTGGATTGGGATAATTTCGGACTTAACGTGAACGGAGACAAACTCAGTCATTTGAGATTTGCTGATGATTTAATACTTTTCTCCGAATGCCCGATGATTTTGGAAAGAATGCTACAACAATTAGCAGATGAAAGTGCAAATGCAGGGCTTACTATGAATATAACAAAGACAAAAGTAATGAGCAATTCCTCACAAAAAAACGCTATTGCAGTTAACAATCAAGAGTTAGAATACGTAAGTGAATACGTTTATCTGGGCCAATTAGTATCACCGACAGAGAGCATGCAGAAAGAAATAGAAAGAAGAATAGCAAACACTTGGAAGAAATTTTGGTCATTGAGTGAAGTAATGAAAAATAAGGAAATGCCTATGGCGGAGAAACGAAAAGTCTTCAATGTTTGCATACTGCCATGTCTTACATACGGATGCCAGACATGGGCCTTAACTGAAAAACAACAAAATAAATTGAATATATGTCAGAATGGGATAGAGAGAAGCGTATTGGGAGTAAGAAGAAGGGATAAAATAGAACTAAAAAAGATCAAAGGAGAGACTAAATTTGGAAAAGTTCAATCAATATGCAGAAAATTAAAATGGCGCTGGACGGGACATATGATGAGAGAAAAGAAAGAAAAATGGACCAGAATAATAACGGAATGGTACCCTAGAGAAAACAAAAGAATCAGAGGAAGACAGCCGAAGCGATGGGAAGACGACTTGAAGCAAGTAGCTGGGCCAGAATGGTTACGTACAGCAAAGGACAGAAGCAAATGGAAATCCTTAGAGGAGGCCTTTGTCGAAAGACAAGCTGTTAAGAGGAGAGATAAGCCGAATGCCGAGATATGTTTTAGTATAAGTTAA

Protein

MGEGIEDHGKYILHYKGETPGQYGVGFLIKRKYMDRIEELKGISERIAILNIKFPVQNSRDELWSIIQVYSPTEADKKQDTNKIEEFYQKLQSTVDTAHKNLIIMGDFNGQIGECRSGEEYIVGRYGNGNRSKNGQHLVNFGLENKLSILNSFFKKKKNKKWTWTSPNGLFKNEIDYIMTNKPKVFKDLSVLHNLNFNSDHKMIRATLRASHTKKSRRLQTGLTPYVDIKNNLEIMNNLKEFLERREQKEYNKTIEATYCYFVNTLKTVARKVSTNNKSILSTETIILLKERKLLLQGNKDKETRKEIAEISKNINKNIRKDRKQKRANTFQYHIKKTGGVKKTFKELESKKNWMPNIKDRQGRSNTKRSEILNIATQYYKELYTSKNEKPATTTTEDMQDIEPIPPILKEETERAITTQKLGKAPGLDQITNELLKTFMPAIVPKLTNLFNEIITAEVIPEDWVRSVIVLLHKKGDKRDINNYRPISLMSNIYKIFSKILLFRLTITLDENQPKEQAGFRSNFSTIDHIHVLRQILQKYREYNKTYYLGFVDFNKAFDSLEHHYIWESLEQQGVHKKYIRILKNIYGKSTAQIKLEKLGEEFPIERGVRQGDPISPKIFSAVLELIFRKLDWDNFGLNVNGDKLSHLRFADDLILFSECPMILERMLQQLADESANAGLTMNITKTKVMSNSSQKNAIAVNNQELEYVSEYVYLGQLVSPTESMQKEIERRIANTWKKFWSLSEVMKNKEMPMAEKRKVFNVCILPCLTYGCQTWALTEKQQNKLNICQNGIERSVLGVRRRDKIELKKIKGETKFGKVQSICRKLKWRWTGHMMREKKEKWTRIITEWYPRENKRIRGRQPKRWEDDLKQVAGPEWLRTAKDRSKWKSLEEAFVERQAVKRRDKPNAEICFSIS

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Uniprot

D7F176   D7F179   D7F178   D7F177   A0A023EXV2   A0A069DZM5   + More
A0A2H1WF27   A0A2H1VS24   A0A2W1BZV1   D7F159   D7F157   D7F165   D7F164   D7F158   D7F160   D7F166   A0A016S1D2   A0A016SG46   A0A016TK11   A0A016W4R1   A0A016T7J7   A0A016WA79   A0A016VVN3   A0A016S795   A0A016S5B2   A0A0K0FAW8   A0A016V419   A0A016VEC1   A0A016VCD9   A0A016WCB8   A0A016WPY4   A0A016U784   A0A016ULU9   A0A016S403   A0A016VCU3   A0A016T590   A0A016VBP7   A0A016SGC3   A0A016WEQ1   A0A016SX67   E3NC15   A0A016VCK8   E3MH09   G0MZ46   A0A023EWU8   A0A2H2JFN0   A0A0P4VWD0   A0A2H2JCS8   A0A0N5C0B1   A0A016TNL1   A0A016TMT8   A0A016TNS4   A0A016TNH6   A0A2H2ITH9   A0A2H2JKX8   A0A2H2JKG1   A0A2W5U8K4   K7IG36   K7IG35   K7I2A1   K7I2A2   K7I2A3   K7ICT2   K7ICT1   A0A069DX96   A0A2H2J2F1   K7H0Q8   A0A016T4C4   A0A016SPR9   K7H0R0   A0A016T5Z1   A0A016T8K0   K7H0Q9   A0A016T636   A0A2H2J8I4   K7HDM3   K7HDM2   K7IBZ6   A0A016VGA0   A0A016WUN2   A0A016W1X2   A0A016WYN9   A0A016SWH8   A0A016US53   K7IBZ5   A0A016SCL7  

EC Number

4.6.1.2

Pubmed

20470440    25474469    26334808    28756777    25730766    27129103    + More

EMBL

FJ265561    ADI61829.1    FJ265564    ADI61832.1    FJ265563    ADI61831.1    + More
FJ265562    ADI61830.1    GBBI01004876    JAC13836.1    GBGD01000380    JAC88509.1    ODYU01008249    SOQ51673.1    ODYU01004088    SOQ43598.1    KZ149907    PZC78256.1    FJ265544    ADI61812.1    FJ265542    ADI61810.1    FJ265550    ADI61818.1    FJ265549    ADI61817.1    FJ265543    ADI61811.1    FJ265545    ADI61813.1    FJ265551    ADI61819.1    JARK01001655    EYB84321.1    JARK01001565    EYB89683.1    JARK01001676    JARK01001446    JARK01001433    EYB83199.1    EYC01126.1    EYC02928.1    JARK01001337    EYC34625.1    JARK01001736    JARK01001462    JARK01001379    JARK01001338    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    JARK01000460    EYC36749.1    JARK01001340    EYC30828.1    JARK01001621    EYB86109.1    JARK01001626    EYB85833.1    JARK01001354    EYC21986.1    JARK01001348    EYC25048.1    EYC25050.1    JARK01000388    EYC37469.1    JARK01000173    EYC41342.1    JARK01001389    EYC11015.1    JARK01001370    EYC16150.1    JARK01001639    EYB85201.1    EYC25046.1    JARK01001473    EYB97806.1    EYC25049.1    JARK01001568    EYB89432.1    JARK01000347    EYC38051.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    DS268591    EFO92565.1    EYC25145.1    DS268444    EFP01729.1    GL379822    EGT48339.1    GBBI01004877    JAC13835.1    GDKW01001596    JAI54999.1    JARK01001424    EYC04316.1    EYC04314.1    EYC04317.1    EYC04315.1    QFQQ01000179    PZR20596.1    GBGD01000453    JAC88436.1    JARK01001475    EYB97550.1    JARK01001531    EYB92324.1    JARK01001470    JARK01000204    EYB98082.1    EYC40602.1    EYB98944.1    EYB98081.1    EYC40601.1    JARK01001346    EYC26445.1    JARK01000109    EYC42952.1    EYC33297.1    JARK01000063    EYC44387.1    JARK01001502    EYB94855.1    JARK01001365    EYC18010.1    JARK01001628    JARK01001583    JARK01001528    JARK01001506    JARK01001467    JARK01001463    JARK01001457    JARK01001432    JARK01001420    JARK01001403    JARK01001371    JARK01001369    JARK01001360    JARK01001353    JARK01001349    JARK01000603    JARK01000080    EYB85741.1    EYB88438.1    EYB92544.1    EYB94540.1    EYB98080.1    EYB98468.1    EYB98899.1    EYB99568.1    EYC03088.1    EYC05014.1    EYC08153.1    EYC15852.1    EYC16408.1    EYC19456.1    EYC22445.1    EYC24734.1    EYC24778.1    EYC24866.1    EYC33488.1    EYC35672.1    EYC43798.1   

Proteomes

UP000024635    UP000035680    UP000008281    UP000008068    UP000005237    UP000046392    + More

PRIDE

D7F176    D7F179    D7F178    D7F177    D7F159    D7F157    + More
D7F165    D7F164    D7F158    D7F160    D7F166   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF00211   Guanylate_cyc
PF07714   Pkinase_Tyr
PF01094   ANF_receptor
PF03372   Exo_endo_phos
PF00069   Pkinase
PF00201   UDPGT

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR029052   Metallo-depent_PP-like       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR001170   ANPR/GUC       
IPR011009   Kinase-like_dom_sf       
IPR028082   Peripla_BP_I       
IPR001054   A/G_cyclase       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       
IPR008271   Ser/Thr_kinase_AS       
IPR017441   Protein_kinase_ATP_BS       
IPR002213   UDP_glucos_trans       

SUPFAM

SSF56219   SSF56219        + More
SSF56112   SSF56112       
SSF53822   SSF53822       
SSF55073   SSF55073       

Gene 3D

3.60.10.10     3.60.21.10     3.30.70.1230    

ProteinModelPortal

D7F176   D7F179   D7F178   D7F177   A0A023EXV2   A0A069DZM5   + More
A0A2H1WF27   A0A2H1VS24   A0A2W1BZV1   D7F159   D7F157   D7F165   D7F164   D7F158   D7F160   D7F166   A0A016S1D2   A0A016SG46   A0A016TK11   A0A016W4R1   A0A016T7J7   A0A016WA79   A0A016VVN3   A0A016S795   A0A016S5B2   A0A0K0FAW8   A0A016V419   A0A016VEC1   A0A016VCD9   A0A016WCB8   A0A016WPY4   A0A016U784   A0A016ULU9   A0A016S403   A0A016VCU3   A0A016T590   A0A016VBP7   A0A016SGC3   A0A016WEQ1   A0A016SX67   E3NC15   A0A016VCK8   E3MH09   G0MZ46   A0A023EWU8   A0A2H2JFN0   A0A0P4VWD0   A0A2H2JCS8   A0A0N5C0B1   A0A016TNL1   A0A016TMT8   A0A016TNS4   A0A016TNH6   A0A2H2ITH9   A0A2H2JKX8   A0A2H2JKG1   A0A2W5U8K4   K7IG36   K7IG35   K7I2A1   K7I2A2   K7I2A3   K7ICT2   K7ICT1   A0A069DX96   A0A2H2J2F1   K7H0Q8   A0A016T4C4   A0A016SPR9   K7H0R0   A0A016T5Z1   A0A016T8K0   K7H0Q9   A0A016T636   A0A2H2J8I4   K7HDM3   K7HDM2   K7IBZ6   A0A016VGA0   A0A016WUN2   A0A016W1X2   A0A016WYN9   A0A016SWH8   A0A016US53   K7IBZ5   A0A016SCL7  

PDB

6AR3     E-value=0.0816039,     Score=87

KEGG

105842305    no KO assigned | (RefSeq) trypsin beta-like

GO

GO:0003964   GO:0004519   GO:0005524   GO:0016021   GO:0035556   GO:0004672   GO:0004383   GO:0016758  

Length:

916

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01131

Exp number, first 60 AAs:

0.00128

Total prob of N-in:

0.00010

outside

1  -  916

 

 

Pi

33.059815

Theta

40.205801

Tajima's D

-1.256107

CLR

0

CSRT

0.0973451327433628

Interpretation

Uncertain