Gene

KWMTBOMO04734

Pre Gene Modal

BGIBMGA009865

Annotation

PREDICTED:_atrial_natriuretic_peptide_receptor_2-like_[Bombyx_mori]

Location

Bomo_Chr8(-):13733599-13742980      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

PlasmaMembrane   Reliability : 2.479

CDS

ATGAAGTCTGCCAGGCGTTCTGTGCTCCTGTACGCGGGTGTTTTAGTCACTGTACTCATCACGTCGGCTGTGCCCTTACTGCTTCTCAGACACGTGGTTTCAACGTTAGAGACATTCACCCACTCATTAAACATGAGTACGGAGAAATTGATAGCCGAGAAACAGAAGAGCGACCTCTTGCTCTCCCGGATGCTCCCGCTGCCAGTTCTGCGGAGGCTGCGGGCACAGAGGACGGTGCCGGCTGAAGCCTTCGACGCGGTCACCATCTTCTTCAGCGATATTGTCGGCTTCACCACCATATCTGCGAATAGCACGCCCATGGAAGTCATCAACATGCTGAACATGCTCTATAAATTGTTTGACGAGAAAATATCTCAATACAACGTTTACAAGGTGGAAACTATAGGAGACGCGTATATGGTGGTCTCTGGTCTGCCACAGAAGAACGGCAGCCGTCACGCGTCCGAGATAGCTGACATGTCATTGTCACTGGTGAGCAGCGTGGAGGAGGCGCGGGTACCGCACCGTCCCGCCGTGCCTCTACGAGTGCGGGCCGGTGTCAACACGGGCCCGTGCGTCGCCGGCGTGGTCGGGACCACCATGCCGAGATACTGCCTTTTTGGCGACACCATCAACACCGCCAGCAGAATGGAGTCTACTGGCGAACCTATGAAAATTCACATCTCGGATTCGACGAAGAGAGCCTTAGACGAGTTCGGTACCTATATCACTGAGTCCAGAGGAATTATTGATATTCCGGGCAAAGGCAGCATGGAAACGTTCTGGTTGCTCGACAAGATCGGAGGAGTACAAAGTGAGAGTCCGCGGTGTCAATTCAACGACTACGACCACAATTTACTGGAACTCATAATTAAATCTTAA

Protein

MKSARRSVLLYAGVLVTVLITSAVPLLLLRHVVSTLETFTHSLNMSTEKLIAEKQKSDLLLSRMLPLPVLRRLRAQRTVPAEAFDAVTIFFSDIVGFTTISANSTPMEVINMLNMLYKLFDEKISQYNVYKVETIGDAYMVVSGLPQKNGSRHASEIADMSLSLVSSVEEARVPHRPAVPLRVRAGVNTGPCVAGVVGTTMPRYCLFGDTINTASRMESTGEPMKIHISDSTKRALDEFGTYITESRGIIDIPGKGSMETFWLLDKIGGVQSESPRCQFNDYDHNLLELIIKS

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Uniprot

H9JK14   A0A194PSH9   A0A0N1PI28   A0A212EVU8   A0A2H1WTN6   A0A0L7LFI9   + More
A0A1D2NJN9   A0A0P5C8P8   A0A182SK07   A0A0P5N0L5   A0A0P6I899   A0A1S4ELA7   A0A0P6BET9   Q7Q9X3   A0A182TVY7   A0A182MSI9   A0A084WTT8   A0A2H1VQ90   A0A182V862   Q17BS6   A0A182HYT8   A0A182X2J4   A0A182Y8M4   A0A182QBM8   A0A182KZE6   A0A182JVW7   A0A212FDS7   W5JDP6   A0A182W3L0   A0A182PQS0   A0A067R086   A0A182N9U7   A0A2R7WVR9   A0A0N1ICN5   A0A182RDZ4   A0A182F900   A0A164RD13   T1HM71   A0A2J7PHM6   A0A1D2ML76   E9GKU2   A0A2A4JGA7   B0WDM1   A0A1B6HPF3   Q17BS5   A0A1B6MQA4   A0A091HSK3   B0XGU2   A0A1Y3BRU1   Q7Q9X4   G1N3D1   U4TTC7   U3IT17   A0A067R2X5   F4X106   A0A158NI27   A0A0K2TJP5   B4LNM4   A0A0C9QND4   A0A093FJC9   T1GUA8   A0A091RZS2   A0A061QLJ7   A0A091MVY1   L5KCF6   A0A139WCS5   H9GJY6   Q8R1P8   A0A0E9X0L5   A0A093Q8U9   A0A093R4F7   A0A087V9F1   H3AE67   A0A2I0M3A9   A0A226EPN3   B4KM65   A0A3L8S379   A0A091H8N2   A0A091JMP6   A0A091QXK6   A0A091VAH8   A0A0Q3XAF4   V9IKY9   A0A2U9C161   S4PX19   A0A094KSS2   E2BEU4   K7FIE2   A0A1D2NFI3   V5G9K2   E0VPI7   A0A2D0QYK5  

EC Number

4.6.1.2

Pubmed

19121390    26354079    22118469    26227816    27289101    12364791    + More
14747013    17210077    24438588    17510324    25244985    20966253    20920257    23761445    24845553    21292972    20838655    23537049    23749191    21719571    21347285    17994087    23258410    18362917    19820115    21881562    15489334    25613341    9215903    23371554    30282656    23622113    20798317    17381049    20566863   

EMBL

BABH01026556    BABH01026557    KQ459595    KPI95714.1    KQ459784    KPJ19950.1    + More
AGBW02012140    OWR45574.1    ODYU01010978    SOQ56430.1    JTDY01001316    KOB74222.1    LJIJ01000028    ODN05186.1    GDIP01173931    JAJ49471.1    GDIQ01149084    JAL02642.1    GDIQ01008120    JAN86617.1    GDIP01030400    JAM73315.1    AAAB01008898    EAA09176.4    AXCM01000458    ATLV01026914    KE525420    KFB53632.1    ODYU01003514    SOQ42404.1    CH477318    EAT43691.1    APCN01005408    AXCN02001201    AGBW02009004    OWR51884.1    ADMH02001458    ETN62492.1    KK853042    KDR12137.1    KK855717    PTY23639.1    KPJ19949.1    LRGB01002190    KZS08548.1    ACPB03017284    NEVH01025135    PNF15831.1    LJIJ01000914    ODM93786.1    GL732550    EFX79739.1    NWSH01001513    PCG71011.1    DS231898    EDS44630.1    GECU01031150    JAS76556.1    EAT43692.1    GEBQ01001932    JAT38045.1    KL217800    KFO98866.1    DS233064    EDS27829.1    MUJZ01002637    OTF83670.1    EAA09177.5    KB630856    KB631023    ERL83905.1    ERL84012.1    ADON01084214    KDR12136.1    GL888520    EGI59866.1    ADTU01016189    ADTU01016190    HACA01008788    CDW26149.1    CH940648    EDW62204.2    GBYB01005079    JAG74846.1    KK390609    KFV54421.1    CAQQ02031877    CAQQ02031878    CAQQ02031879    KK937289    KFQ47905.1    GBFC01000092    JAC59246.1    KK838640    KFP81628.1    KB030846    ELK09022.1    KQ971362    KYB25768.1    BC023420    AAH23420.1    GBXM01012325    JAH96252.1    KL672239    KFW85011.1    KL438435    KFW93530.1    KL484857    KFO09243.1    AFYH01074404    AFYH01074405    AKCR02000044    PKK24170.1    LNIX01000003    OXA58781.1    CH933808    EDW08729.1    QUSF01000077    RLV95590.1    KL525367    KFO90995.1    KK502299    KFP22284.1    KK804800    KFQ31346.1    KK733826    KFR00129.1    LMAW01000094    KQL60805.1    JR050741    AEY61347.1    CP026253    AWP09399.1    GAIX01005808    JAA86752.1    KL266973    KFZ62278.1    GL447857    EFN85810.1    AGCU01118388    AGCU01118389    LJIJ01000057    ODN04011.1    GALX01001646    JAB66820.1    DS235366    EEB15293.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000037510    UP000094527    + More
UP000075901    UP000079169    UP000007062    UP000075902    UP000075883    UP000030765    UP000075903    UP000008820    UP000075840    UP000076407    UP000076408    UP000075886    UP000075882    UP000075881    UP000000673    UP000075920    UP000075885    UP000027135    UP000075884    UP000075900    UP000069272    UP000076858    UP000015103    UP000235965    UP000000305    UP000218220    UP000002320    UP000054308    UP000001645    UP000030742    UP000016666    UP000007755    UP000005205    UP000008792    UP000015102    UP000010552    UP000007266    UP000001646    UP000053258    UP000008672    UP000053872    UP000198287    UP000009192    UP000276834    UP000053119    UP000053605    UP000051836    UP000246464    UP000008237    UP000007267    UP000009046    UP000221080   

PRIDE

H9JK14   

Pfam

PF00211   Guanylate_cyc        + More
PF08376   NIT
PF07701   HNOBA
PF07714   Pkinase_Tyr

Interpro

IPR018297   A/G_cyclase_CS        + More
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR013587   Nitrate/nitrite_sensing       
IPR011645   HNOB_dom_associated       
IPR011009   Kinase-like_dom_sf       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR000719   Prot_kinase_dom       

SUPFAM

SSF55073   SSF55073        + More
SSF56112   SSF56112       

Gene 3D

3.30.70.1230    

ProteinModelPortal

H9JK14   A0A194PSH9   A0A0N1PI28   A0A212EVU8   A0A2H1WTN6   A0A0L7LFI9   + More
A0A1D2NJN9   A0A0P5C8P8   A0A182SK07   A0A0P5N0L5   A0A0P6I899   A0A1S4ELA7   A0A0P6BET9   Q7Q9X3   A0A182TVY7   A0A182MSI9   A0A084WTT8   A0A2H1VQ90   A0A182V862   Q17BS6   A0A182HYT8   A0A182X2J4   A0A182Y8M4   A0A182QBM8   A0A182KZE6   A0A182JVW7   A0A212FDS7   W5JDP6   A0A182W3L0   A0A182PQS0   A0A067R086   A0A182N9U7   A0A2R7WVR9   A0A0N1ICN5   A0A182RDZ4   A0A182F900   A0A164RD13   T1HM71   A0A2J7PHM6   A0A1D2ML76   E9GKU2   A0A2A4JGA7   B0WDM1   A0A1B6HPF3   Q17BS5   A0A1B6MQA4   A0A091HSK3   B0XGU2   A0A1Y3BRU1   Q7Q9X4   G1N3D1   U4TTC7   U3IT17   A0A067R2X5   F4X106   A0A158NI27   A0A0K2TJP5   B4LNM4   A0A0C9QND4   A0A093FJC9   T1GUA8   A0A091RZS2   A0A061QLJ7   A0A091MVY1   L5KCF6   A0A139WCS5   H9GJY6   Q8R1P8   A0A0E9X0L5   A0A093Q8U9   A0A093R4F7   A0A087V9F1   H3AE67   A0A2I0M3A9   A0A226EPN3   B4KM65   A0A3L8S379   A0A091H8N2   A0A091JMP6   A0A091QXK6   A0A091VAH8   A0A0Q3XAF4   V9IKY9   A0A2U9C161   S4PX19   A0A094KSS2   E2BEU4   K7FIE2   A0A1D2NFI3   V5G9K2   E0VPI7   A0A2D0QYK5  

PDB

3ET6     E-value=1.10746e-39,     Score=409

KEGG

101742292    no KO assigned | (RefSeq) atrial natriuretic peptide receptor 2-like

GO

GO:0000166   GO:0035556   GO:0009190   GO:0016849   GO:0016021   GO:0006182   GO:0007165   GO:0007168   GO:0004383   GO:0001653   GO:0005886   GO:0005524   GO:0004672   GO:0016829   GO:0016791   GO:0006511   GO:0016020   GO:0035023   GO:0005515   GO:0016742   GO:0003824  

Length:

293

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

23.95196

Exp number, first 60 AAs:

22.80617

Total prob of N-in:

0.99864

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  293

 

 

Pi

237.296826

Theta

187.428231

Tajima's D

0.68449

CLR

0

CSRT

0.569121543922804

Interpretation

Uncertain