Gene

KWMTBOMO04733

Pre Gene Modal

BGIBMGA009866

Annotation

PREDICTED:_membrane-bound_alkaline_phosphatase-like_[Bombyx_mori]

Location

Bomo_Chr8(-):13706585-13713280      View in EpiBrowser

Full name

Alkaline phosphatase       + More
Membrane-bound alkaline phosphatase      

Location in the cell

Cytoplasmic   Reliability : 1.083 Extracellular   Reliability : 1.005 Mitochondrial   Reliability : 1.519

CDS

ATGTTACAGGTTTTAGCTCCTTTAAACAAGAAAGTAGCTAAGAATGTCATCTTATTTCTTGGGGACGGCATGAGCATTACAACGCTCGCCGCCACGAGAGCATACCTCGGCCAGCAGCGGGGACTAAATGGTGAAGAGCTCAAACTGAGTTTCGAAATTTTCCCGTACACCGGCTTAGCTAAGACGTATTGTGTAGATAATAACGTAGCGGACTCTGCGTGTAGTGGTACCGCGTATCTGACTGGAGTGAAGGCCAACAGTGGAACTGTAGGTCTTACCGCCGCCGTCAAGAGAGGAGACTGCGAAGGACAAATTGAAGGCAGACATTCTGTCACCGGACTTATGGATTGGGCGCAACGGGCCGTCAAATCTACTGGTCTCGTGACCACAACACGAGTGACCCACGCCACTCCCGCCGCCGCATACGCTCATTCAGCCGATAGGAGATGGGAAGCTGACACCGATCTTCCAAGCAAAGGCCCTCGCTGCGATGACATAGCGACGCAATTAGTTAGAGGACGTATCGGCAGTAAAATTGATGTGGTCCTTGGTGGAGGTCGACACAATTTCTATCCTAAAAACGAGATAGACCCCGAAGGATACTCCGGTTATCGAAGCGATGGTGTCAATCTAGCAAGGGAATGGTTGATTAAGAAGAAATCGCAGGGACGCACCCCGAAATACCTTTACAATAGAAACGACTTACTGAATCTTAAAGTCAACGAATACGACAGCTTATTAGGTTTGTTCAGCCCTGATCACATGCCGTATCATTTGGAAGCTGACGGTGATGATCCGACGCTGACGGAAATGACTAGGAAAGCCATTGAAATGCTGTCGAAAAACAAAAACGGATTTTTCTTGTTCGTTGAAGGTGGAAGAATAGACACGGCGCATCACGAAACGAAAGCTCGCAAAGCTTTGGATGAGACAGCAGAGTTCGCGAAAGCCGTTGAAGCGGCCGTCAGGATGGTGGACGCCGAAGAGACCCTAATCGTTGTGACATCGGACCACAGTCATACGATGACATACAGTGGATACAGTAAGAGAGGCACCGATATCCTAGGATTTACCAATAAGGTAATTTCTGTTTTATGA

Protein

MLQVLAPLNKKVAKNVILFLGDGMSITTLAATRAYLGQQRGLNGEELKLSFEIFPYTGLAKTYCVDNNVADSACSGTAYLTGVKANSGTVGLTAAVKRGDCEGQIEGRHSVTGLMDWAQRAVKSTGLVTTTRVTHATPAAAYAHSADRRWEADTDLPSKGPRCDDIATQLVRGRIGSKIDVVLGGGRHNFYPKNEIDPEGYSGYRSDGVNLAREWLIKKKSQGRTPKYLYNRNDLLNLKVNEYDSLLGLFSPDHMPYHLEADGDDPTLTEMTRKAIEMLSKNKNGFFLFVEGGRIDTAHHETKARKALDETAEFAKAVEAAVRMVDAEETLIVVTSDHSHTMTYSGYSKRGTDILGFTNKVISVL

Catalytic Activity

a phosphate monoester + H2O = an alcohol + phosphate

Cofactor

Mg(2+)
Zn(2+)

Similarity

Belongs to the alkaline phosphatase family.

Keywords

Cell membrane   Complete proteome   Direct protein sequencing   Glycoprotein   GPI-anchor   Hydrolase   Lipoprotein   Magnesium   Membrane   Metal-binding   Phosphoprotein   Reference proteome   Signal   Zinc  

Feature

chain  Alkaline phosphatase
propeptide  Removed in mature form

Uniprot

H9JK15   A0A2A4JNE4   A0A2H1W0P4   A0A212ESB5   A0A194PQX4   A0A2H5CLH1   + More
A0A3S2P0P5   A0A0N1IIK6   U5EGZ8   B0W3S9   A0A1Q3EV69   A0A1Q3EV65   A0A0T6BBC6   A0A1B6DLR4   A0A1B0CIG9   A0A182QLW3   A0A3G1LC34   A0A2J7PHL4   A0A182XYI9   A0A182RTZ7   A0A067QRJ2   A0A182JL64   W5JSA4   Q16WV8   A0A182MT69   A0A182P207   A0A182JP07   A0A084VQQ6   A0A1S4FLA4   E0VEB3   A0A182NKM7   A0A182WJL0   A0A182FG53   A0A0P6JST2   A0A182SLH6   A0A182KQV2   A0A182VAE3   A0A182WZ34   A0A182I2X2   Q7QJ58   A0A1B6MN90   A0A1B6MFZ1   A0A1J1ID93   A0A182THI0   A0A2L1IQA0   C0JBW2   A0A2J7PHK8   A0A182GRD2   B2ZZW3   A5A746   H9JH21   A0A1B6DQA4   B2ZZW7   B2ZZX0   P29523   B2ZZX1   C6L8N8   A0A139WCZ9   A0A3S2PC92   A0A2P8YNZ8   A0A1L8DJJ7   A0A2H5CLJ8   A0A2H5CLG8   H9JH27   A0A0K8WLU3   G3GBT4   A0A2L1IQA2   C0JBW1   I6PI83   B2ZZW5   A0A1B6D5A0   A0A194R254   A0A2W1BI04   A0A2H1WA01   A0A0A1WHU6   A0A182QLC7   H9JXN7   C6L8N9   B2ZZW4   A0A0M4F783   A0A1W4X350   Q7KXT0   B2ZZW8   A0A194R2N2   A0A182FNG2   A0A067QT98   B4JEK3   A0A194Q8I8   J9JZX4   B4LW25   A0A1L8DMR0   W8BIN1   B2ZZX2   A0A182PSM3   A0A182R8V1   A0A1L8DMR2   A0A0L0C934   B4K503   A0A1L8DMY4  

EC Number

3.1.3.1

Pubmed

19121390    22118469    26354079    25244985    24845553    20920257    + More
23761445    17510324    24438588    20566863    26999592    20966253    12364791    14747013    17210077    29415259    26483478    1756175    14508679    18362917    19820115    29403074    21840855    28756777    25830018    17994087    24495485    26108605   

EMBL

BABH01026553    NWSH01000914    PCG73557.1    ODYU01005624    SOQ46661.1    AGBW02012833    + More
OWR44383.1    KQ459595    KPI95712.1    KY912923    AUH25164.1    RSAL01000066    RVE49395.1    KQ459784    KPJ19948.1    GANO01003229    JAB56642.1    DS231833    EDS32226.1    GFDL01015845    JAV19200.1    GFDL01015846    JAV19199.1    LJIG01002313    KRT84627.1    GEDC01020887    GEDC01010675    GEDC01009792    JAS16411.1    JAS26623.1    JAS27506.1    AJWK01013324    AXCN02000551    KY922835    AUF74484.1    NEVH01025135    PNF15822.1    KK853042    KDR12134.1    ADMH02000578    ETN65800.1    CH477553    EAT39089.1    AXCM01001173    ATLV01015292    KE525006    KFB40300.1    DS235088    EEB11719.1    GDUN01000056    JAN95863.1    APCN01000188    AAAB01008807    EAA03918.4    GEBQ01002563    JAT37414.1    GEBQ01005162    JAT34815.1    CVRI01000047    CRK98187.1    MF741670    AVD96953.1    FJ175381    ACN29683.1    PNF15827.1    JXUM01082264    JXUM01082265    KQ563301    KXJ74098.1    AB379672    BAG41968.1    AB270698    BAF62124.1    BABH01037520    GEDC01009448    JAS27850.1    AB379674    BAG41972.1    AB379676    BAG41975.1    D90454    AB055428    AB379677    BAG41976.1    AB516292    BAH95821.1    KQ971362    KYB25767.1    RSAL01000106    RVE47295.1    PYGN01000459    PSN45953.1    GFDF01007570    JAV06514.1    KY912922    AUH25163.1    KY912924    AUH25165.1    BABH01037533    BABH01037534    GDHF01000489    JAI51825.1    JF825967    AEG79734.1    MF741672    AVD96955.1    FJ175380    ACN29682.1    JF979062    AFI81420.1    AB379673    BAG41970.1    GEDC01016426    JAS20872.1    KQ460870    KPJ11777.1    KZ150047    PZC74488.1    ODYU01007279    SOQ49911.1    GBXI01016061    JAC98230.1    AXCN02000252    BABH01044837    AB516293    BAH95822.1    BAG41969.1    CP012526    ALC47682.1    BAB62746.2    BAG41971.1    BAG41973.1    KPJ11779.1    KDR12135.1    CH916369    EDV93134.1    KQ459562    KPI99720.1    ABLF02034222    ABLF02034224    CH940650    EDW66530.1    GFDF01006336    JAV07748.1    GAMC01005400    JAC01156.1    BAG41977.1    GFDF01006338    JAV07746.1    JRES01000835    KNC27894.1    CH933806    EDW13974.1    GFDF01006337    JAV07747.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000283053    UP000053240    + More
UP000002320    UP000092461    UP000075886    UP000235965    UP000076408    UP000075900    UP000027135    UP000075880    UP000000673    UP000008820    UP000075883    UP000075885    UP000075881    UP000030765    UP000009046    UP000075884    UP000075920    UP000069272    UP000075901    UP000075882    UP000075903    UP000076407    UP000075840    UP000007062    UP000183832    UP000075902    UP000069940    UP000249989    UP000007266    UP000245037    UP000092553    UP000192223    UP000001070    UP000007819    UP000008792    UP000037069    UP000009192   

PRIDE

H9JK15    B2ZZW3    A5A746    H9JH21    B2ZZW7    B2ZZX0    + More
P29523    B2ZZX1    C6L8N8    H9JH27    B2ZZW5    H9JXN7    C6L8N9    B2ZZW4    Q7KXT0    B2ZZW8    B2ZZX2   

Pfam

PF00245   Alk_phosphatase

Interpro

IPR017850   Alkaline_phosphatase_core_sf        + More
IPR001952   Alkaline_phosphatase       
IPR018299   Alkaline_phosphatase_AS       

SUPFAM

SSF53649   SSF53649       

Gene 3D

3.40.720.10    

CDD

cd16012  ALP

ProteinModelPortal

H9JK15   A0A2A4JNE4   A0A2H1W0P4   A0A212ESB5   A0A194PQX4   A0A2H5CLH1   + More
A0A3S2P0P5   A0A0N1IIK6   U5EGZ8   B0W3S9   A0A1Q3EV69   A0A1Q3EV65   A0A0T6BBC6   A0A1B6DLR4   A0A1B0CIG9   A0A182QLW3   A0A3G1LC34   A0A2J7PHL4   A0A182XYI9   A0A182RTZ7   A0A067QRJ2   A0A182JL64   W5JSA4   Q16WV8   A0A182MT69   A0A182P207   A0A182JP07   A0A084VQQ6   A0A1S4FLA4   E0VEB3   A0A182NKM7   A0A182WJL0   A0A182FG53   A0A0P6JST2   A0A182SLH6   A0A182KQV2   A0A182VAE3   A0A182WZ34   A0A182I2X2   Q7QJ58   A0A1B6MN90   A0A1B6MFZ1   A0A1J1ID93   A0A182THI0   A0A2L1IQA0   C0JBW2   A0A2J7PHK8   A0A182GRD2   B2ZZW3   A5A746   H9JH21   A0A1B6DQA4   B2ZZW7   B2ZZX0   P29523   B2ZZX1   C6L8N8   A0A139WCZ9   A0A3S2PC92   A0A2P8YNZ8   A0A1L8DJJ7   A0A2H5CLJ8   A0A2H5CLG8   H9JH27   A0A0K8WLU3   G3GBT4   A0A2L1IQA2   C0JBW1   I6PI83   B2ZZW5   A0A1B6D5A0   A0A194R254   A0A2W1BI04   A0A2H1WA01   A0A0A1WHU6   A0A182QLC7   H9JXN7   C6L8N9   B2ZZW4   A0A0M4F783   A0A1W4X350   Q7KXT0   B2ZZW8   A0A194R2N2   A0A182FNG2   A0A067QT98   B4JEK3   A0A194Q8I8   J9JZX4   B4LW25   A0A1L8DMR0   W8BIN1   B2ZZX2   A0A182PSM3   A0A182R8V1   A0A1L8DMR2   A0A0L0C934   B4K503   A0A1L8DMY4  

PDB

1SHQ     E-value=2.06659e-83,     Score=787

KEGG

101742146    K01077 alkaline phosphatase [EC:3.1.3.1] | (RefSeq) membrane-bound alkaline phosphatase-like

PATHWAY

00730    Thiamine metabolism - Bombyx mori (domestic silkworm)
00790    Folate biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004035   GO:0016791   GO:0016021   GO:0005886   GO:0031225   GO:0046872   GO:0001666   GO:0035094   GO:0003824   GO:0008152   GO:0006182   GO:0006511   GO:0016020   GO:0035023   GO:0005515   GO:0016742  

PANTHER

PTHR11596  

Subcellular location

Cell membrane  

Length:

365

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.38664

Exp number, first 60 AAs:

2.38525

Total prob of N-in:

0.10665

outside

1  -  365

 

 

Pi

142.62143

Theta

126.799601

Tajima's D

-0.517305

CLR

0.497816

CSRT

0.24158792060397

Interpretation

Uncertain