Gene

KWMTBOMO04703

Pre Gene Modal

BGIBMGA009810

Annotation

PREDICTED:_G-protein_coupled_receptor_Mth2-like_[Bombyx_mori]

Location

Bomo_Chr8(-):12745094-12780703      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.987

CDS

ATGTCCGTTGTTTTTATGTTATTCGTGTTTGTCGCGACGGGTTTGTGTTGGAAATCGCATAGACTGGAAATTTGTGACGACGAGAACAGCGTGGATATCACAGCGGGCACCCATTTATCGGGTGGTGTGATCTACCACGACGGGGTGCGGTACGACCAAAGCGAATATTATACTGACAAGAGAACCGGATCGGACCGGGGGTGCGTGTGCTCGAAAGGGACGTGCATAAGAAAGTGTTGCCCCCTCGGCTATGGCTACAATTATAAAAGCAAACAATGTGTGAAAGTTTACGAGAGATTCGCGCCGCCCGTTTGGGACAACTATGCGTACGAAATGTTAAAAGTGAACGCTTCCGACATATTCCATTTTGTGCCCGGGAAAATGAACTGCACCGATTCCAAGACGAGGATACGAATAGGGCAAGCCACAAAGAATTTTGTCTTGAGAGTGGATGGTAAACTGTACATACAAATACCAGAGAGCATTCCTCCGTGGCTCGTTCAGACCCCTGATGAATACTGCATCGACACGTTCGTCAGAGAAGACCCAACAACCGGAGAGAGGACCTCAAGTCTGGACGCGCTGATCTGCTTCGCTGATAAAGTTAACAACGAACAATACGTCCTAAGATTCACTTGCATGCTGATTTCCTGCTTGTTCATCCTGGCCACGGTAGCAGTGTACGCGTGGCTACCAGAGCTACGGAACTTGCACGGCAGGGTGCTCATGGCGTACCTTCTCAGTCTGTTCGTCGGCTTCACGTTCCTGGCGACAATGCAAATACTGCTGACGATCAACAACATAACAGTGACGACATGCGTTTATTTCACATTCGTGATCTACTATTCGTTGCTGGCGGCCTTCTTTTGGCTCAACGTCATGTGCTTCGACATCTGGTGGACTTTCAGCGGCAAACGTGGAAAATCTTTAGAGAAAATGTCACTGCGGACCCGCTTCGTGGCATATTCTTTATACGCGTTTGGTATACCTACTGTGCTGACTGCTCTACTTGTTGGATTGGAGTTCTCGGGTCTTCCGCCGCATCCCTTATTACCAATGATCCGGCAACAAGGATGTTTTATTTACGGTACGAGTAAACTCATTTACCTGTACGGTCCGATTTCAATACTCTGCATCGCCAATATGACTTTCTTCGTGCTGACCGCCGTGAAAATAGCGCAGATTAAGAAGCAAACGTCGGTGCTCAAATCGAAAGACAGTTCCACGCACGATCAGCACCGGAATGATCGACAAAGGCTGCTCCTTTACATCAAGTTGCTTGCGGTAATGGGTGTTAGCTGGATCCTAGAGGTAGTCAGCGCTATATACCCAGAAGCCGAAGATATCTGGAAATTTACAGACGCCTACAACGTCCTTATCGGATTAATCATCTTCATCATTTTCGTCTGCAAGAGAAAAATCTTCAGATTGATCAAGAAGAGGATTAAGCAGAAGTTCCGACGATCGAACAATGAGAGCAGAGAGTTAAAGGAGATAGTCGATAAGAGAATGAGACGCTGGCAAAATAATTCGAACCAAAGAGCCAGCTTAGAAACTATCAGAACCTCAATCGGTGTCGACTCTGATGCTACCGTTAGAAACACGACAAATGTATGA

Protein

MSVVFMLFVFVATGLCWKSHRLEICDDENSVDITAGTHLSGGVIYHDGVRYDQSEYYTDKRTGSDRGCVCSKGTCIRKCCPLGYGYNYKSKQCVKVYERFAPPVWDNYAYEMLKVNASDIFHFVPGKMNCTDSKTRIRIGQATKNFVLRVDGKLYIQIPESIPPWLVQTPDEYCIDTFVREDPTTGERTSSLDALICFADKVNNEQYVLRFTCMLISCLFILATVAVYAWLPELRNLHGRVLMAYLLSLFVGFTFLATMQILLTINNITVTTCVYFTFVIYYSLLAAFFWLNVMCFDIWWTFSGKRGKSLEKMSLRTRFVAYSLYAFGIPTVLTALLVGLEFSGLPPHPLLPMIRQQGCFIYGTSKLIYLYGPISILCIANMTFFVLTAVKIAQIKKQTSVLKSKDSSTHDQHRNDRQRLLLYIKLLAVMGVSWILEVVSAIYPEAEDIWKFTDAYNVLIGLIIFIIFVCKRKIFRLIKKRIKQKFRRSNNESRELKEIVDKRMRRWQNNSNQRASLETIRTSIGVDSDATVRNTTNV

Similarity

Belongs to the G-protein coupled receptor Fz/Smo family.

Uniprot

A0A2A4JZW9   A0A3S2LCX1   A0A2A4K0U7   A0A2A4K0F5   A0A194QT14   V9LVR6   + More
A0S6W9   A0A1E1WH08   A0A212FD97   A0A1E1WCB0   A0A1E1WN64   A0A194PWW7   A0A2A4JF49   J7EQT7   A0A1Q3FKG5   A0A1Q3FKC1   B0X3W8   A0A1L8DJU0   A0A182Q5Y6   A0A1L8DK28   A0A3S2NWT9   A0A182V7J0   A0A182TDZ9   A0A182N958   A0A167L5T8   A0A182LLL5   A0A2Y9D3K1   A0A182I170   A0A2Y9D3M1   Q7PNT9   A0A2J7R7H5   A0A023ESZ7   A0A182GN29   A0A067QUD2   A0A2J7RJJ1   A0A1W4WTI3   A0A182PLA5   A0A084WK40   A0A1B6JEQ5   A0A1W4WTH9   A0A1B6G5F1   J9JKN2   A0A182IYC9   A0A1W4X4A5   A0A1I8Q8U0   A0A182N959   A0A182GN30   A0A1W4X335   A0A1I8Q8T7   A0A1I8Q8W7   A0A1B6DQS8   A0A182IR24   A0A1W4X330   Q16RE5   A0A336MQY2   A0A182FDT7   Q16RE7   A0A3L8D8G7   A0A1W4X4E4   A0A1B6IUT9   A0A1B6IBM7   A0A2M4BMW9   A7UU57   A0A182V1K9   A0A182QW48   A0A182I172   Q7PNU1   A0A2S2QB80   A0A2M4BM26   A0A2M4CFX2   A0A2M4BL65   A0A182WLQ8   A0A0K8W8Z7   A0A1B6KQY4   A0A0K8V9N1   A0A2Y9D3T7   E2AKW8   A0A336MK75   A0A182LLL3   A0A336MLF9   A0A182MPY5   A0A034W0F2   A0A182THK7   A0A158NSZ5   B0X3X1   A0A1Y1NC30   A0A0N0BJ15   E0VM50   A0A151I3Y4   A0A1Q3FLM5  

Pubmed

26354079    22118469    20966253    12364791    24945155    26483478    + More
24845553    24438588    17510324    30249741    14747013    17210077    20798317    25348373    21347285    28004739    20566863   

EMBL

NWSH01000314    PCG77537.1    RSAL01000041    RVE50936.1    PCG77538.1    PCG77539.1    + More
KQ461154    KPJ08612.1    JQ809653    AFW03960.1    DQ295917    ABC24708.1    GDQN01004782    JAT86272.1    AGBW02009085    OWR51711.1    GDQN01006455    JAT84599.1    GDQN01002620    JAT88434.1    KQ459595    KPI95630.1    NWSH01001619    PCG70677.1    HQ188201    AEM43036.1    GFDL01007020    JAV28025.1    GFDL01007037    JAV28008.1    DS232324    EDS40045.1    GFDF01007356    JAV06728.1    AXCN02000556    GFDF01007357    JAV06727.1    RVE50935.1    KU363814    ANB32479.1    APCN01000032    AAAB01008960    EAA11607.3    NEVH01006732    PNF36788.1    GAPW01001180    JAC12418.1    JXUM01014371    JXUM01014372    JXUM01014373    JXUM01014374    JXUM01014375    JXUM01014376    JXUM01014377    JXUM01014378    KQ560401    KXJ82611.1    KK852944    KDR13486.1    NEVH01002992    PNF40994.1    ATLV01024093    KE525349    KFB50584.1    GECU01010087    JAS97619.1    GECZ01012105    JAS57664.1    ABLF02038161    JXUM01014387    JXUM01014388    JXUM01014389    JXUM01014390    KXJ82612.1    GEDC01018773    GEDC01009262    GEDC01000043    JAS18525.1    JAS28036.1    JAS37255.1    CH477715    EAT36975.2    UFQT01001465    SSX30677.1    EAT36973.2    QOIP01000011    RLU16797.1    GECU01017005    JAS90701.1    GECU01023436    JAS84270.1    GGFJ01005162    MBW54303.1    EDO63835.1    APCN01000034    EAA11592.2    GGMS01005791    MBY74994.1    GGFJ01004986    MBW54127.1    GGFL01000036    MBW64214.1    GGFJ01004654    MBW53795.1    GDHF01004805    JAI47509.1    GEBQ01026124    JAT13853.1    GDHF01016786    JAI35528.1    GL440425    EFN65885.1    SSX30676.1    SSX30675.1    AXCM01007268    GAKP01011745    GAKP01011744    JAC47208.1    ADTU01025461    ADTU01025462    EDS40048.1    GEZM01007071    JAV95423.1    KQ435724    KOX78511.1    DS235289    EEB14456.1    KQ976472    KYM83995.1    GFDL01006627    JAV28418.1   

Proteomes

UP000218220    UP000283053    UP000053240    UP000007151    UP000053268    UP000002320    + More
UP000075886    UP000075903    UP000075902    UP000075884    UP000075882    UP000076407    UP000075840    UP000007062    UP000235965    UP000069940    UP000249989    UP000027135    UP000192223    UP000075885    UP000030765    UP000007819    UP000075880    UP000095300    UP000008820    UP000069272    UP000279307    UP000075920    UP000000311    UP000075883    UP000005205    UP000053105    UP000009046    UP000078540   

PRIDE

J7EQT7   

Pfam

PF00002   7tm_2        + More
PF06652   Methuselah_N
PF01534   Frizzled

Interpro

IPR017981   GPCR_2-like        + More
IPR036272   Methuselah_N_sf       
IPR010596   Methuselah_N_dom       
IPR000832   GPCR_2_secretin-like       
IPR023311   Methusela_ecto_dom_2       
IPR000539   Frizzled/Smoothened_TM       

SUPFAM

SSF63877   SSF63877       

Gene 3D

2.170.180.11    

CDD

cd00251  Mth_Ecto

ProteinModelPortal

A0A2A4JZW9   A0A3S2LCX1   A0A2A4K0U7   A0A2A4K0F5   A0A194QT14   V9LVR6   + More
A0S6W9   A0A1E1WH08   A0A212FD97   A0A1E1WCB0   A0A1E1WN64   A0A194PWW7   A0A2A4JF49   J7EQT7   A0A1Q3FKG5   A0A1Q3FKC1   B0X3W8   A0A1L8DJU0   A0A182Q5Y6   A0A1L8DK28   A0A3S2NWT9   A0A182V7J0   A0A182TDZ9   A0A182N958   A0A167L5T8   A0A182LLL5   A0A2Y9D3K1   A0A182I170   A0A2Y9D3M1   Q7PNT9   A0A2J7R7H5   A0A023ESZ7   A0A182GN29   A0A067QUD2   A0A2J7RJJ1   A0A1W4WTI3   A0A182PLA5   A0A084WK40   A0A1B6JEQ5   A0A1W4WTH9   A0A1B6G5F1   J9JKN2   A0A182IYC9   A0A1W4X4A5   A0A1I8Q8U0   A0A182N959   A0A182GN30   A0A1W4X335   A0A1I8Q8T7   A0A1I8Q8W7   A0A1B6DQS8   A0A182IR24   A0A1W4X330   Q16RE5   A0A336MQY2   A0A182FDT7   Q16RE7   A0A3L8D8G7   A0A1W4X4E4   A0A1B6IUT9   A0A1B6IBM7   A0A2M4BMW9   A7UU57   A0A182V1K9   A0A182QW48   A0A182I172   Q7PNU1   A0A2S2QB80   A0A2M4BM26   A0A2M4CFX2   A0A2M4BL65   A0A182WLQ8   A0A0K8W8Z7   A0A1B6KQY4   A0A0K8V9N1   A0A2Y9D3T7   E2AKW8   A0A336MK75   A0A182LLL3   A0A336MLF9   A0A182MPY5   A0A034W0F2   A0A182THK7   A0A158NSZ5   B0X3X1   A0A1Y1NC30   A0A0N0BJ15   E0VM50   A0A151I3Y4   A0A1Q3FLM5  

PDB

5L7I     E-value=0.057895,     Score=86

KEGG

101746106    K04599 G protein-coupled receptor Mth (Methuselah protein) | (RefSeq) G-protein coupled receptor Mth

GO

GO:0016021   GO:0004930   GO:0007166   GO:0006950   GO:0004888   GO:0016020   GO:0035023   GO:0005515   GO:0016742   GO:0003824  

SignalP

Position:   1 - 21,         Likelihood:  0.985790

 

 

Length:

538

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

155.83759

Exp number, first 60 AAs:

0.01608

Total prob of N-in:

0.00128

outside

1  -  206

TMhelix

207  -  229

inside

230  -  240

TMhelix

241  -  263

outside

264  -  277

TMhelix

278  -  300

inside

301  -  320

TMhelix

321  -  343

outside

344  -  367

TMhelix

368  -  390

inside

391  -  420

TMhelix

421  -  443

outside

444  -  457

TMhelix

458  -  475

inside

476  -  538

 

 

Pi

237.992529

Theta

174.406396

Tajima's D

1.431284

CLR

0.186471

CSRT

0.771711414429278

Interpretation

Uncertain