Gene

KWMTBOMO04689

Pre Gene Modal

BGIBMGA009815

Annotation

PREDICTED:_mutS_protein_homolog_4-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr8(+):12546409-12551932      View in EpiBrowser

Full name

DNA mismatch repair protein      

Location in the cell

Cytoplasmic   Reliability : 1.737 Nuclear   Reliability : 2.166

CDS

ATGTGTTGTCTTCTTGGTGTGCTTGGCCCGACTTATACTGTTGGAGGGATTAGGGCATTGAGGGCTTCTATCTTGCAACCGTCTTGCAATAAACAATTAATTGAATCAAAACTAGATGTTCTTCAAGATTTAATTGAAAATGACAATGGTTTGATGGCTGATTTACAGGACATTTTGAAAAGGCTATCAGATATTGATAAAATATTATTCTTGTGCGTTGAGCATAATATTCAAAATGCTGACAAATTAGGAGAGGCGCAGCTCAATCAAGTGTTAATTCTAAAAACGACAATGAATATGGTACCAAAACTAGTTGAAGCTTTGAATCGTGCCGAAAGTGGTCTGTTAAGACAATTTAAAACGGATTTCGAAAATCCACATTACAATGAAATTGCCGAACGCATAAAAAATATCATACAAGACGACGCGCATTTCGAGAAGGGTGTTATGGGAAATCTCCAAAGATGTTTTGCAGTCAAGCCCGACATTAACGGACTCCTTGATGTGGCCAGAAGGACGTATTCTGAATTAATAGATGACATACAGAAAATTGTCGAACAGCTCAGCGAGACATACGACCTGCCTCTGCGGCTAAACCAAAACGTTATGAAAGGATTCCACATAGTTTTACCTATAGCTCCAAAAAACAGACGCAATTTCAGTATTGAAGATCTGCCCCCAATTTTCATACAGGTACACAACAACGGAGCCAGCGTATCGATGTCGACTGAAGAACTTGTAGTTCTCGATCAACAGGCAAAGGAATCTTTGAATGAAATACAAAGAATGAGTAACATAGTTATCGACGCATTATTGAAAGACTTAAGGCCATACATGTCGAGTCTGTACAAATTATGCGAGAACGTTGCTGAAATTGACATCCTCCTGGCATTAGCACAGGTTCGGATTGTACATATTTTAATGGAACAAAAGCATTATAACTCGTACCTCTTAACTTCTTATATGTTCCAGGCTAGCATGGTAGGGTCGTATATCAGACCGGAATTTAACAGCTATTTAGAAATAAGAAACAGCGTCCATCCGTTATTGGATTATAACAGTCACGTGATGCCAGTTCCAAATGACATAAATGCCAGCCCAGAATACAATTTCACTATAATCACCGGTCCGAATATGGGCGGCAAAAGTGTTTATATAAAACAGATTGCTATTATGCATGTTATGGCGCAACAGATTGGTTGTTTCTTGCCCGCTACTAATGCTGTACTGCGACTTAGTGACAGAATATTTTCGAGAATCGGTTTCAACGACAGCGTTGAGTTGAACGCTTCTACTTTTGTTTTCGAGATGAAAGAGATGCAGCATATTTTAAAAGGACTGACGCCATCAAGCCTGGTCATAATAGACGAACTCTGTCGCGGTACAACATACGAAGAGGGAGTCAGTATAGCTTGGGCGATCTGTGAAGAATTAATATTATCTGACGCTTTCACGTTCTTCACAACACACTTTTTATATTTGACGAAATTGCAACACCTTTACTACAACGTGGTCAATCGCCATACTACTGTTAAGGAAGAAAACGTTGATGAACTGAACGATTCTCATAAAAAACTGATTTATGAACATAAAATAGAATTAGGAGTTACGAATATAAAAAACTATGGATTGGCTTTGGCAGCAAAAACAAATTTACCAGAAGACACCGTAAAACTTGCATTTGAACTAGCAGAACTTATGACCATTGATGAAGAGACGCCAGAAACCTGCCTGCCGCAAAGAAATGACGAAAGAGAACTTTATATTTTAAATGCAGAGCTACAAAAAGAATATAGAAAAAATGGAGGTTCAGAGAAAGCTTTGGAAGCCACCATAAACAAATTCAAAGAAAATAATGCTGAACTCGTTGAAAAATTAAAAATTCAAACCAGCAACAATCCTTCTAGTTCAAGTAACGAATGTTGGTCAAGTGACCCTAAAAAAGGCTATTCAAATAATCCCAGTGGCAGTGGTAAAAAACCATTGGAATATAATAGAACACCCGAACGACTAAATACCGAGTCTTTAACAGTTAATGAAAAACCCGGTGCTACAGAGATATACCCACAAATCAAATCTTCCAATGAACTATTGACAAGCATGAAAACTATAAAGAACAAATCTCATACGTACATTGACGAAGACATACAAACGATTGGTATAGAAAACGTTAATACTAAATTAAATAAATTATCTCCAAATTGTTTAAATGAAAGTAATCATTACATTGAAGAATACCAAAATACGTTAAGCACGGAACATGAGAATTCACTCAGTGATGACGATTTATCAGAAGCACTAACGCAGGTTATAGGAGAATGTTCCAATTCATTCGATCATTCAATAGATAACGAGGATAGGGCTACCGATGAAACCCTTATGATAGAAACGATTAATGAAATTAATGAGGAATTGAACAATGCATCTAATTATAATTTTAACGATTTAATTTTAACGCCACCAATCGCTTTCAGGGACATTTCGTAG

Protein

MCCLLGVLGPTYTVGGIRALRASILQPSCNKQLIESKLDVLQDLIENDNGLMADLQDILKRLSDIDKILFLCVEHNIQNADKLGEAQLNQVLILKTTMNMVPKLVEALNRAESGLLRQFKTDFENPHYNEIAERIKNIIQDDAHFEKGVMGNLQRCFAVKPDINGLLDVARRTYSELIDDIQKIVEQLSETYDLPLRLNQNVMKGFHIVLPIAPKNRRNFSIEDLPPIFIQVHNNGASVSMSTEELVVLDQQAKESLNEIQRMSNIVIDALLKDLRPYMSSLYKLCENVAEIDILLALAQVRIVHILMEQKHYNSYLLTSYMFQASMVGSYIRPEFNSYLEIRNSVHPLLDYNSHVMPVPNDINASPEYNFTIITGPNMGGKSVYIKQIAIMHVMAQQIGCFLPATNAVLRLSDRIFSRIGFNDSVELNASTFVFEMKEMQHILKGLTPSSLVIIDELCRGTTYEEGVSIAWAICEELILSDAFTFFTTHFLYLTKLQHLYYNVVNRHTTVKEENVDELNDSHKKLIYEHKIELGVTNIKNYGLALAAKTNLPEDTVKLAFELAELMTIDEETPETCLPQRNDERELYILNAELQKEYRKNGGSEKALEATINKFKENNAELVEKLKIQTSNNPSSSSNECWSSDPKKGYSNNPSGSGKKPLEYNRTPERLNTESLTVNEKPGATEIYPQIKSSNELLTSMKTIKNKSHTYIDEDIQTIGIENVNTKLNKLSPNCLNESNHYIEEYQNTLSTEHENSLSDDDLSEALTQVIGECSNSFDHSIDNEDRATDETLMIETINEINEELNNASNYNFNDLILTPPIAFRDIS

Description

Component of the post-replicative DNA mismatch repair system (MMR).

Similarity

Belongs to the DNA mismatch repair MutS family.

Uniprot

H9JJW4   A0A2H1VXG5   A0A194PQU0   A0A194QYE7   A0A2A4IVB4   A0A3S2P2U8   + More
A0A0L7KVA3   A0A1S3J8M3   A0A291S6W3   A0A0L8GSV3   A0A310S973   R7UWW9   X1X5V3   A0A210Q4E9   A0A087ZW46   A0A2T7PYR7   G3NYW7   C3Z1V1   A0A3Q3J7J5   A0A3B3Y865   A0A315V2X0   A0A3Q2XGU5   X1WBE0   A0A3Q1JBY1   A0A3B3V842   A0A3Q2PPU5   A0A2I4BLW9   A0A087XAI6   A0A2Y9D7G1   A0A151NJZ5   A7SM04   A0A3B5ALJ5   A0A3B4T9K8   A0A091CZD1   W5MZK1   F1P6X2   A0A1W5AVU3   A0A1U7T652   A0A2U3XQC5   A0A091Q636   A0A087WQN0   A0A3B4YRE2   F1M9U4   A0A091SRK3   A0A3Q0GHF2   M3YHF4   A0A0Q3MKY6   I3MR69   H0UVG2   A0A093JB45   A0A3P9J148   A0A2I2USD9   A0A093NKS1   A0A3Q7TGP9   A0A3Q0DCQ3   H3AEP5   F6TF84   A0A3B5QL95   Q7TNA6   E2RJA9   M3XLC8   A0A091TZC5   A0A3Q1EZY6   A0A087WQG8   U3JF60   A0A091HJ69   A0A2Y9IWB1   A0A0A0AD33   A0A2Y9G427   H0WWT9   A0A099ZCQ0   H3DJ20   F6QL61  

Pubmed

19121390    26354079    26227816    28992199    23254933    28812685    + More
18563158    29703783    23594743    22293439    17615350    16341006    19468303    15057822    21993624    17554307    17975172    9215903    17431167    23542700    15527976    15496914   

EMBL

BABH01040635    ODYU01004714    SOQ44894.1    KQ459595    KPI95677.1    KQ461154    + More
KPJ08601.1    NWSH01006823    PCG63224.1    RSAL01000041    RVE50926.1    JTDY01005259    KOB67187.1    MF432997    ATL75348.1    KQ420579    KOF79909.1    KQ763441    OAD55100.1    AMQN01005970    KB297235    ELU10757.1    ABLF02007369    ABLF02007370    ABLF02007371    ABLF02054782    NEDP02005059    OWF43559.1    PZQS01000001    PVD38561.1    GG666573    EEN53468.1    NHOQ01002481    PWA16448.1    BX465227    AYCK01005147    AKHW03002907    KYO36835.1    DS469703    EDO35291.1    KN123809    KFO23250.1    AHAT01003728    AAEX03004895    AAEX03004896    KK687050    KFQ15001.1    AC087184    AABR07013859    AABR07013860    KK483858    KFQ61347.1    AEYP01045765    AEYP01045766    AEYP01045767    AEYP01045768    AEYP01045769    AEYP01045770    AEYP01045771    AEYP01045772    LMAW01001570    KQK83168.1    AGTP01063383    AGTP01063384    AGTP01063385    AAKN02005014    AAKN02005015    KL217284    KFV76134.1    AANG04003279    KL224841    KFW64726.1    AFYH01155080    AFYH01155081    AFYH01155082    AFYH01155083    AFYH01155084    JSUE03001697    JSUE03001698    JSUE03001699    AY351586    AAQ20789.1    KK407711    KFQ83127.1    AGTO01011277    KL217539    KFO96338.1    KL871554    KGL92419.1    AAQR03023681    AAQR03023682    AAQR03023683    AAQR03023684    AAQR03023685    AAQR03023686    AAQR03023687    KL891373    KGL78610.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000218220    UP000283053    UP000037510    + More
UP000085678    UP000053454    UP000014760    UP000007819    UP000242188    UP000005203    UP000245119    UP000007635    UP000001554    UP000261600    UP000261480    UP000264820    UP000000437    UP000265040    UP000261500    UP000265000    UP000192220    UP000028760    UP000248480    UP000050525    UP000001593    UP000261400    UP000261420    UP000028990    UP000018468    UP000002254    UP000192224    UP000189704    UP000245341    UP000000589    UP000261360    UP000002494    UP000189705    UP000000715    UP000051836    UP000005215    UP000005447    UP000053875    UP000265200    UP000011712    UP000054081    UP000286640    UP000189706    UP000008672    UP000006718    UP000002852    UP000257200    UP000016665    UP000054308    UP000248482    UP000053858    UP000248481    UP000005225    UP000053641    UP000007303    UP000008225   

PRIDE

H9JJW4    A0A087WQN0    F1M9U4   

Pfam

PF00488   MutS_V        + More
PF05192   MutS_III
PF05188   MutS_II
PF05190   MutS_IV

Interpro

IPR000432   DNA_mismatch_repair_MutS_C        + More
IPR036678   MutS_con_dom_sf       
IPR011184   DNA_mismatch_repair_Msh2       
IPR007696   DNA_mismatch_repair_MutS_core       
IPR036187   DNA_mismatch_repair_MutS_sf       
IPR027417   P-loop_NTPase       
IPR007860   DNA_mmatch_repair_MutS_con_dom       
IPR007861   DNA_mismatch_repair_MutS_clamp       
IPR017261   DNA_mismatch_repair_MutS/MSH       

SUPFAM

SSF48334   SSF48334        + More
SSF53150   SSF53150       
SSF52540   SSF52540       

Gene 3D

3.30.420.110    

ProteinModelPortal

H9JJW4   A0A2H1VXG5   A0A194PQU0   A0A194QYE7   A0A2A4IVB4   A0A3S2P2U8   + More
A0A0L7KVA3   A0A1S3J8M3   A0A291S6W3   A0A0L8GSV3   A0A310S973   R7UWW9   X1X5V3   A0A210Q4E9   A0A087ZW46   A0A2T7PYR7   G3NYW7   C3Z1V1   A0A3Q3J7J5   A0A3B3Y865   A0A315V2X0   A0A3Q2XGU5   X1WBE0   A0A3Q1JBY1   A0A3B3V842   A0A3Q2PPU5   A0A2I4BLW9   A0A087XAI6   A0A2Y9D7G1   A0A151NJZ5   A7SM04   A0A3B5ALJ5   A0A3B4T9K8   A0A091CZD1   W5MZK1   F1P6X2   A0A1W5AVU3   A0A1U7T652   A0A2U3XQC5   A0A091Q636   A0A087WQN0   A0A3B4YRE2   F1M9U4   A0A091SRK3   A0A3Q0GHF2   M3YHF4   A0A0Q3MKY6   I3MR69   H0UVG2   A0A093JB45   A0A3P9J148   A0A2I2USD9   A0A093NKS1   A0A3Q7TGP9   A0A3Q0DCQ3   H3AEP5   F6TF84   A0A3B5QL95   Q7TNA6   E2RJA9   M3XLC8   A0A091TZC5   A0A3Q1EZY6   A0A087WQG8   U3JF60   A0A091HJ69   A0A2Y9IWB1   A0A0A0AD33   A0A2Y9G427   H0WWT9   A0A099ZCQ0   H3DJ20   F6QL61  

PDB

1FW6     E-value=1.81595e-34,     Score=368

KEGG

101745041    K08740 DNA mismatch repair protein MSH4 | (RefSeq) mutS protein homolog 4-like

GO

GO:0005524   GO:0006298   GO:0030983   GO:0000228   GO:0000795   GO:0000712   GO:0032300   GO:0008094   GO:0007131   GO:0032301   GO:0003677   GO:0005713   GO:0007292   GO:0001541   GO:0007129   GO:0007283   GO:0006564   GO:0032784   GO:0005089   GO:0035023   GO:0005515   GO:0016742   GO:0003824  

Subcellular location

Nucleus  

Length:

828

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.10579

Exp number, first 60 AAs:

0.07268

Total prob of N-in:

0.00370

outside

1  -  828

 

 

Pi

179.959134

Theta

169.287557

Tajima's D

0.305681

CLR

0.133867

CSRT

0.459027048647568

Interpretation

Uncertain