Gene

KWMTBOMO04673

Pre Gene Modal

BGIBMGA005290

Annotation

PREDICTED:_target_of_rapamycin_complex_subunit_lst8_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr8(-):11926061-11929668      View in EpiBrowser

Full name

Target of rapamycin complex subunit lst8      

Alternative Name

G protein beta subunit-like
MTOR associated protein, LST8 homolog

Location in the cell

Extracellular   Reliability : 1.932

CDS

ATGGCTGGTGATACCACTGCTTCTCTTGGAGGATCGCAGGTGGCTTTAGTAACAGGAGGCTACGATCATACTATCAAGCTATGGCAGGCACACAGTGGTGTTTGTTTACGAACAATGCAGCATCCAGATTCGCAAGTGAACAGCTTGGAGATCTCACCAACATCGATGGTAGCAGCAGCTGGATTTCAGCATATACGGTTATATGATCTTAGTAGTGCCAATCCAGACCCGGTCACAACTTTTGAGGACATCTCCAAAAACGTATCTCGAGTTGGGTTTCAGAAAAATGGCACTTGGATGTACACAGGAGGTGAGGACTGCACAGCCAGGATATGGGATCCCAGGGCTGCACCACGTACAAGGTGTCAAAAGATATTCCAAGTTCAAGCTCCGGTGAATGCAGTAATGCTTCATCCTGATCAGTCCCAGATAATGGTTGGAGACCAGAGTGGCATTATACATATATGGGATCTGAAAACGGATCAAAATGAACAACTGATACCAGAAGCGGAGGCGTCGATTCAGGACATAGCTATTGATCCAGCCGGCAAGATGATGGCGGCTGTTAATAACAAGGGCAACTGCTACGTGTGGTCGTTGAGCGGACAACCACCGCACCCTGTGCCCAAAAAACACATTACTGCACATTCTAAATATGCTTTACGGTGTAAATTTAGCCCAGATTCAACCATGTTGGTGACGACGTCGGGCGACTGCTCGGCCAAGATCTGGCGCACGAGCGACTGGGCGCTGTTGCGAGAGCTACGGCGCGACACGCAGCGATGGGTCTGGGACGCAGCCTTTACGCTTGATTCTCGATTTTTATTCACTGGTTCATCGGATAGTTATGCTCGATTATGGAACATTGAGCGTGGCACGCTTGAACGGGAGTACTGCGGTCATCAGAAAGCCATCACAGCACTCGCGTTTAAAGATCAACCTGTTTGA

Protein

MAGDTTASLGGSQVALVTGGYDHTIKLWQAHSGVCLRTMQHPDSQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQPV

Similarity

Belongs to the WD repeat LST8 family.

Keywords

Complete proteome   Cytoplasm   Reference proteome   Repeat   WD repeat  

Feature

chain  Target of rapamycin complex subunit lst8

Uniprot

H9J6Z8   A0A2A4IVE1   A0A2H1VL60   A0A194QUC8   A0A194PWZ5   A0A3S2TNJ6   + More
A0A212ENA9   A0A1E1WR98   A0A2H4NI40   E2AJ87   A0A154P3D2   A0A310S5E1   A0A195BP66   A0A158P2T3   F4W5V0   A0A195C1L4   A0A195DFF8   A0A195EYR4   A0A088A396   E2BSR9   A0A0L7QXT1   A0A026WDJ3   A0A1B6GBQ8   A0A1B6J6D9   A0A151XHN7   A0A0P4VWE1   A0A069DYL4   E0VCT7   A0A0M9A9Q1   R4WIV9   A0A1W4WXM4   D6X0M7   R7UH14   A0A1S3HA20   T1HL77   X1ZAF0   J9JTC1   A0A0P4W8E3   C4WXU6   V5R076   K1QE38   A0A1Y1L789   E9FTA7   A0A3Q3GMH4   A0A3Q3JZL1   A0A0P7UDP4   A0A3Q1I928   A0A067QS08   A0A3B3BLQ2   W5MD16   A0A1A8QHP9   A0A1A8PKK5   A0A3B4H2F3   A0A3Q1FMC0   A0A3B5A572   A0A3Q2W1V8   A0A3Q4I5G6   A0A3Q1BNG9   I3KUX0   A0A3P9BKE1   A0A3P8RTF4   A0A3P8Q3C1   A0A060X7C9   A0A1S3Q5C1   A0A2C9LA02   A0A3Q3VZ10   A0A0N8CKF5   A0A3B3R8C4   H2LD78   A0A1A8IH57   A0A1A7WV45   A0A1A8CQP0   A0A3P9K8W0   A0A1A8GNL9   A0A1A8B3J9   A0A3P8Q4G5   A0A3B4WU75   A0A3Q3ADV3   A0A146Z1W5   A0A0S7H509   A0A3B5QGB1   A0A087Y8C8   A0A3B3Y565   A0A315V1S3   A0A3Q3LGA2   A0A3B4C031   A0A3Q2YWQ1   A0A3P8UHP2   W5U9B8   Q4S4G3   H3BAC1   H3D5U2   A0A3P8YT99   A0A0M4N079   T2M5T1   A0A2I4C416   B2GPI2   Q803V5   A0A2R8QP30   C1BWT3  

Pubmed

19121390    26354079    22118469    29125860    20798317    21347285    + More
21719571    24508170    30249741    27129103    26334808    20566863    23691247    18362917    19820115    23254933    22992520    28004739    21292972    24845553    29451363    25186727    24755649    15562597    29240929    17554307    23542700    29703783    24487278    23127152    15496914    9215903    25069045    24065732    23594743    20433749   

EMBL

BABH01014062    NWSH01007005    NWSH01002536    PCG63152.1    PCG68038.1    ODYU01003149    + More
SOQ41536.1    KQ461154    KPJ08585.1    KQ459595    KPI95660.1    RSAL01000041    RVE50909.1    AGBW02013681    OWR42982.1    GDQN01007014    GDQN01001491    JAT84040.1    JAT89563.1    MF038046    ATV91622.1    GL439967    EFN66527.1    KQ434809    KZC06357.1    KQ770178    OAD52667.1    KQ976432    KYM87436.1    ADTU01007470    ADTU01007471    GL887695    EGI70426.1    KQ978379    KYM94505.1    KQ980903    KYN11625.1    KQ981905    KYN33363.1    GL450241    EFN81315.1    KQ414704    KOC63339.1    KK107260    QOIP01000001    EZA54038.1    RLU27042.1    GECZ01009891    JAS59878.1    GECU01012978    GECU01010772    JAS94728.1    JAS96934.1    KQ982116    KYQ59916.1    GDKW01001586    JAI55009.1    GBGD01002185    JAC86704.1    DS235065    EEB11193.1    KQ435719    KOX78813.1    AK417420    BAN20635.1    KQ971371    EFA10009.2    KB301444    ELU05495.1    ACPB03003772    AMQN01007807    ABLF02038090    ABLF02038101    GDRN01064148    JAI64885.1    AK342844    BAH72716.1    KF638284    AHB23863.1    JH817341    EKC35172.1    GEZM01062874    GEZM01062873    JAV69444.1    GL732524    EFX89677.1    JARO02002605    KPP72280.1    KK853751    KDQ85827.1    AHAT01013494    AHAT01013495    HAEH01011747    HAEI01015431    SBR93036.1    HAEF01014031    HAEG01008312    SBR81544.1    AERX01002257    FR905048    CDQ75366.1    GDIQ01248313    GDIQ01207264    GDIP01123007    LRGB01003123    JAK03412.1    JAL80707.1    KZS04195.1    HAED01010226    HAEE01016180    SBQ96438.1    HADW01008024    HADX01012002    SBP09424.1    HADZ01017149    HAEA01004079    SBP81090.1    HAEB01012197    HAEC01003912    SBQ71989.1    HADY01023354    HAEJ01001967    SBP61839.1    GCES01025975    JAR60348.1    GBYX01447638    JAO33818.1    AYCK01025998    AYCK01025999    NHOQ01002507    PWA16143.1    JT408614    AHH38405.1    CAAE01014738    CAG04469.1    AFYH01059147    AFYH01059148    AFYH01059149    AFYH01059150    AFYH01059151    KR075847    ALE20566.1    HAAD01001396    CDG67628.1    BC164355    AAI64355.1    BC044176    BC068352    BX571974    BT079062    ACO13486.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000007151    + More
UP000000311    UP000076502    UP000078540    UP000005205    UP000007755    UP000078542    UP000078492    UP000078541    UP000005203    UP000008237    UP000053825    UP000053097    UP000279307    UP000075809    UP000009046    UP000053105    UP000192223    UP000007266    UP000014760    UP000085678    UP000015103    UP000007819    UP000005408    UP000000305    UP000261660    UP000261600    UP000034805    UP000265040    UP000027135    UP000261560    UP000018468    UP000261460    UP000257200    UP000261400    UP000264840    UP000261580    UP000257160    UP000005207    UP000265160    UP000265080    UP000265100    UP000193380    UP000087266    UP000076420    UP000261620    UP000076858    UP000261540    UP000001038    UP000265180    UP000265200    UP000261360    UP000264800    UP000265000    UP000002852    UP000028760    UP000261480    UP000261640    UP000261440    UP000264820    UP000265120    UP000221080    UP000008672    UP000007303    UP000265140    UP000192220    UP000000437   

PRIDE

H9J6Z8   

Pfam

PF00400   WD40        + More
PF12894   ANAPC4_WD40

Interpro

IPR015943   WD40/YVTN_repeat-like_dom_sf        + More
IPR001680   WD40_repeat       
IPR037588   MLST8       
IPR017986   WD40_repeat_dom       
IPR036322   WD40_repeat_dom_sf       
IPR019775   WD40_repeat_CS       
IPR020472   G-protein_beta_WD-40_rep       
IPR011047   Quinoprotein_ADH-like_supfam       
IPR024977   Apc4_WD40_dom       

SUPFAM

SSF50978   SSF50978        + More
SSF50998   SSF50998       

Gene 3D

2.130.10.10    

ProteinModelPortal

H9J6Z8   A0A2A4IVE1   A0A2H1VL60   A0A194QUC8   A0A194PWZ5   A0A3S2TNJ6   + More
A0A212ENA9   A0A1E1WR98   A0A2H4NI40   E2AJ87   A0A154P3D2   A0A310S5E1   A0A195BP66   A0A158P2T3   F4W5V0   A0A195C1L4   A0A195DFF8   A0A195EYR4   A0A088A396   E2BSR9   A0A0L7QXT1   A0A026WDJ3   A0A1B6GBQ8   A0A1B6J6D9   A0A151XHN7   A0A0P4VWE1   A0A069DYL4   E0VCT7   A0A0M9A9Q1   R4WIV9   A0A1W4WXM4   D6X0M7   R7UH14   A0A1S3HA20   T1HL77   X1ZAF0   J9JTC1   A0A0P4W8E3   C4WXU6   V5R076   K1QE38   A0A1Y1L789   E9FTA7   A0A3Q3GMH4   A0A3Q3JZL1   A0A0P7UDP4   A0A3Q1I928   A0A067QS08   A0A3B3BLQ2   W5MD16   A0A1A8QHP9   A0A1A8PKK5   A0A3B4H2F3   A0A3Q1FMC0   A0A3B5A572   A0A3Q2W1V8   A0A3Q4I5G6   A0A3Q1BNG9   I3KUX0   A0A3P9BKE1   A0A3P8RTF4   A0A3P8Q3C1   A0A060X7C9   A0A1S3Q5C1   A0A2C9LA02   A0A3Q3VZ10   A0A0N8CKF5   A0A3B3R8C4   H2LD78   A0A1A8IH57   A0A1A7WV45   A0A1A8CQP0   A0A3P9K8W0   A0A1A8GNL9   A0A1A8B3J9   A0A3P8Q4G5   A0A3B4WU75   A0A3Q3ADV3   A0A146Z1W5   A0A0S7H509   A0A3B5QGB1   A0A087Y8C8   A0A3B3Y565   A0A315V1S3   A0A3Q3LGA2   A0A3B4C031   A0A3Q2YWQ1   A0A3P8UHP2   W5U9B8   Q4S4G3   H3BAC1   H3D5U2   A0A3P8YT99   A0A0M4N079   T2M5T1   A0A2I4C416   B2GPI2   Q803V5   A0A2R8QP30   C1BWT3  

PDB

6BCX     E-value=6.80841e-106,     Score=980

KEGG

101740945    K08266 target of rapamycin complex subunit LST8 | (RefSeq) target of rapamycin complex subunit lst8

PATHWAY

04136    Autophagy - other - Bombyx mori (domestic silkworm)
04140    Autophagy - animal - Bombyx mori (domestic silkworm)
04150    mTOR signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0031931   GO:0031929   GO:0031932   GO:0032008   GO:0032956   GO:0005737   GO:0005515   GO:0016192   GO:0030131   GO:0005622   GO:0009058   GO:0005089   GO:0035023   GO:0016742   GO:0003824  

PANTHER

PTHR19842  

Subcellular location

Cytoplasm  

Length:

315

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00966999999999998

Exp number, first 60 AAs:

0.00857

Total prob of N-in:

0.01396

outside

1  -  315

 

 

Pi

134.638648

Theta

160.576346

Tajima's D

-0.734812

CLR

176.246259

CSRT

0.189640517974101

Interpretation

Possibly Positive selection