Gene

KWMTBOMO04671

Pre Gene Modal

BGIBMGA005291

Annotation

PREDICTED:_protein_EMRE_homolog?_mitochondrial_[Papilio_machaon]

Location

Bomo_Chr8(-):11918858-11919498      View in EpiBrowser

Full name

Essential MCU regulator, mitochondrial      

Location in the cell

Nuclear   Reliability : 1.1

CDS

ATGGCGATTTTTAGACTAACTCGTCTTGTGGCACAGTCCAAGACTTTAACGAAACACGAACCGATTATACATCTAAGAACTGCAACTACTACTCCAACTGGTGCTATTTTACCCGAACCACAAAAACAACCTTTTGGTTTGCTGTGTGTTGTTTTTGCTGTCGTACCGGGCTTACTAATCGGAGCTGCTATTAGTAAAAACATAGCAAATTTCCTTGAAGAAAATGAACTCTTTGTACCATCGGACGATGACGATGATGACGACTAA

Protein

MAIFRLTRLVAQSKTLTKHEPIIHLRTATTTPTGAILPEPQKQPFGLLCVVFAVVPGLLIGAAISKNIANFLEENELFVPSDDDDDDD

Description

Essential regulatory subunit of the mitochondrial calcium uniporter MCU channel, a protein that mediates calcium uptake into mitochondria.
Essential regulatory subunit of the mitochondrial calcium uniporter (mcu) channel, a protein that mediates calcium uptake into mitochondria.

Similarity

Belongs to the SMDT1/EMRE family.

Keywords

Calcium   Calcium transport   Complete proteome   Ion transport   Membrane   Mitochondrion   Mitochondrion inner membrane   Reference proteome   Transit peptide   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Essential MCU regulator, mitochondrial

Uniprot

H9J6Z9   A0A2H1VMQ1   I4DJI6   A0A194QSU0   A0A212ENB3   A0A0L7L8W3   + More
A0A2J7QXL0   E2BLJ5   A0A195BMU3   A0A195F2G1   V5GDE8   A0A151J2T5   F4WIC0   E9ISY1   A0A195CM30   A0A151XBK9   A0A026WQC6   D6X268   A0A0L7QXS6   B4P4R3   A0A310SDD0   A0A1B2AJ28   B4HNC6   B4QBV9   Q7JX57   B3NLP8   Q17ED3   A0A0N0BGU2   N6T3F5   A0A1W4UZN6   A0A1Q3FJU5   A0A1Q3FIV0   A0A182QVS4   A0A182JQZ0   B3MH49   A0A2M3ZC54   B0W2N0   T1E7K1   B4GBM0   Q290M9   A0A2A3E8X3   A0A084VD24   A0A2M3ZCK6   W5JRN2   A0A2P6KEH4   A0A0K8TPV1   B4LKW9   A0A182RL01   A0A336MPI5   A0A1D2MJW3   A0A2M4C4T6   B4J5I1   A0A1I8MES3   H2MII7   A0A3P9IBG9   A0A3P9LV58  

Pubmed

19121390    22651552    26354079    22118469    26227816    20798317    + More
21719571    21282665    24508170    18362917    19820115    17994087    17550304    22936249    10731132    12537572    12537569    27099988    28726639    17510324    23537049    15632085    24438588    20920257    23761445    26369729    27289101    25315136    17554307   

EMBL

BABH01014061    ODYU01003149    SOQ41534.1    AK401454    KQ459595    BAM18076.1    + More
KPI95657.1    KQ461154    KPJ08583.1    AGBW02013681    OWR42980.1    JTDY01002167    KOB71968.1    NEVH01009378    PNF33326.1    GL449033    EFN83432.1    KQ976440    KYM86487.1    KQ981856    KYN34648.1    GALX01006442    JAB62024.1    KQ980404    KYN16192.1    GL888175    EGI66051.1    GL765434    EFZ16365.1    KQ977580    KYN01763.1    KQ982330    KYQ57678.1    KK107139    EZA57896.1    KQ971371    EFA09907.1    KQ414704    KOC63356.1    CM000158    EDW91686.1    KQ761039    OAD58386.1    KX531345    ANY27155.1    CH480816    EDW48408.1    CM000362    CM002911    EDX07619.1    KMY94769.1    AE013599    AY095085    CH954179    EDV55023.1    CH477283    EAT44843.1    KQ435767    KOX75281.1    APGK01054008    KB741242    KB631761    ENN72088.1    ERL85910.1    GFDL01007273    JAV27772.1    GFDL01007597    JAV27448.1    AXCN02002653    CH902619    EDV35808.1    GGFM01005386    MBW26137.1    DS231827    EDS29338.1    GAMD01002967    JAA98623.1    CH479181    EDW32278.1    CM000071    EAL25333.1    KZ288322    PBC28233.1    ATLV01011135    KE524643    KFB35868.1    GGFM01005478    MBW26229.1    ADMH02000297    ETN67067.1    MWRG01014206    PRD24725.1    GDAI01001447    JAI16156.1    CH940648    EDW60773.1    UFQT01001564    SSX31029.1    LJIJ01001044    ODM93221.1    GGFJ01011010    MBW60151.1    CH916367    EDW00744.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000037510    UP000235965    + More
UP000008237    UP000078540    UP000078541    UP000078492    UP000007755    UP000078542    UP000075809    UP000053097    UP000007266    UP000053825    UP000002282    UP000001292    UP000000304    UP000000803    UP000008711    UP000008820    UP000053105    UP000019118    UP000030742    UP000192221    UP000075886    UP000075881    UP000007801    UP000002320    UP000008744    UP000001819    UP000242457    UP000030765    UP000000673    UP000008792    UP000075900    UP000094527    UP000001070    UP000095301    UP000001038    UP000265200    UP000265180   

PRIDE

H9J6Z9    Q7JX57   

Pfam

PF10161   DDDD

Interpro

IPR018782   MCU_reg       

ProteinModelPortal

H9J6Z9   A0A2H1VMQ1   I4DJI6   A0A194QSU0   A0A212ENB3   A0A0L7L8W3   + More
A0A2J7QXL0   E2BLJ5   A0A195BMU3   A0A195F2G1   V5GDE8   A0A151J2T5   F4WIC0   E9ISY1   A0A195CM30   A0A151XBK9   A0A026WQC6   D6X268   A0A0L7QXS6   B4P4R3   A0A310SDD0   A0A1B2AJ28   B4HNC6   B4QBV9   Q7JX57   B3NLP8   Q17ED3   A0A0N0BGU2   N6T3F5   A0A1W4UZN6   A0A1Q3FJU5   A0A1Q3FIV0   A0A182QVS4   A0A182JQZ0   B3MH49   A0A2M3ZC54   B0W2N0   T1E7K1   B4GBM0   Q290M9   A0A2A3E8X3   A0A084VD24   A0A2M3ZCK6   W5JRN2   A0A2P6KEH4   A0A0K8TPV1   B4LKW9   A0A182RL01   A0A336MPI5   A0A1D2MJW3   A0A2M4C4T6   B4J5I1   A0A1I8MES3   H2MII7   A0A3P9IBG9   A0A3P9LV58  

PDB

6O5B     E-value=1.50087e-08,     Score=135

KEGG

101740660    K22830 essential MCU regulator, mitochondrial | (RefSeq) protein EMRE homolog, mitochondrial

GO

GO:0036444   GO:1990246   GO:0051560   GO:0031305   GO:0006851   GO:0045089   GO:0050829   GO:0005515   GO:0005634   GO:0008033   GO:0009058   GO:0005089   GO:0035023   GO:0016742   GO:0003824  

PANTHER

PTHR33904  

Subcellular location

Mitochondrion inner membrane  

Length:

88

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

19.00989

Exp number, first 60 AAs:

14.93744

Total prob of N-in:

0.71412

POSSIBLE N-term signal

sequence

inside

1  -  44

TMhelix

45  -  64

outside

65  -  88

 

 

Pi

224.272127

Theta

197.932762

Tajima's D

0.41885

CLR

0.285758

CSRT

0.490475476226189

Interpretation

Possibly Positive selection