Gene

KWMTBOMO04670  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005519

Annotation

PREDICTED:_protein_flightless-1_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr8(+):11905409-11917946      View in EpiBrowser

Full name

Protein flightless-1      

Alternative Name

Flightless-I

Location in the cell

Cytoplasmic   Reliability : 2.825

CDS

ATGCACTACGTAACGCGCTTGTACCGAGTCCACGGCGCCGGCAACAGCATCCACCTGGAGCCGGTCGCGGTGCGCGCCGCCTCGCTCGACCCGAGATACGTCTTCGTGCTCGACACCGGACTCATAATTTATCTCTGGTACGGTAAGAAAGCTAAGAACACCCTCAAGTCCAAAGCTCGTTTGTTTGCGGAGAAGATAAACAAAGAGGAGAGGAAGAACAAAGCGGAGCTGATCGCGGAACCGCCGGGGAAGGAACCCAAAAGTTTCTGGCAGATATTGGGGCACGAAGAGGATGTGCCTTTTGTACCCGAGGAGCACGTGGGCGAGTGGAGCAGCCGGGCGGTGCGGCTGTACCGCGTGGAGCTCGGCATGGGCTACCTCGAGCTGCCGCAGCCCGGGCCCGCGCCGCTGTCCCGGGGCGCGCTCGCCACTAGGAACGTTTACATCCTCGACGCGCACCTCGACGTCTTCGTCTGGTTCGGTAAGAAGTCCTCCCGGCTGGTGCGAGCAGCTGCGGTGAAGCTCGCGCAGGAGCTGTTCAACATGGTGACGCGGCCGCCGCACGCGCTCGTCACGCGTCTCCAAGAAGGGACCGAGACACAGGTGTTCAAAACGTATTTCCTGGGCTGGGACGAAATCATAGCGGTGGACTTCACGAGAACTGCAGAGTCTGTGGCGAGGACCGGGGTAGACCTCGCCAGCTGGGCCAAACAACAGGAGACTAAGGCCGATCTATCAGCGCTGTTCACGCCGAGGCAGCCGGCGATGACGGCGTCAGAAGCGAAGACCCTCGCAGACGAGTGGAACGAAGACCTGGAAGCGATGGAGGCCTTCGTGCTGGAGGGACGCCACTTCGTCCGGTTGCCCGAGAACGAACTGGGGGTCTTCTACAGCTGTGATTGCTACGTGTTCCTCTGCAGATATGTCTTGTGTCCTGATGCCGAGGAAGAGAGCGAGGGCTCCAACGTGGATCACGAGACGGAAGACGACGGTGAATCCGCCACCTGGGTCGTGTACTTCTGGCAGGGACGTAGGGCTCCCAACATGGGCTGGCTGACGTTCACCTTCGGTCTTGAGAGGAAGTTCAAGCAGCTCTGCAAGCGCCTTGAGGTCGTCCGGACGCACCAGCAGCAAGAGAGCCTCAAGTTCCTCTCGCACTTCCACAGGCAATTCGTGCTCAGAGACGGCAAGAGGAATCTTAAACCGGAGGGTCGTCTGCCCGTCGAGTTGTTCGAGCTGCGTAGTAACGGCTCCGCGCTCTGCACCAGGCTGGTCCAGGTCAAAGCGGAGGCGTCCCAACTGAACAGTGCCTTCTGCTACATTTTAAACGTACCGCTGGAAGGTAACGGGGAAACGTCGTCCGCCATCGTGTACGCGTGGATCGGGAGCAAAAGCGACCCCGACTCCGCGCGACTCATCGAGCAAATGGCCGAAGATAAGTTCAACAACCCGTGGGTCAGCCTACAGGTATTAACGGAGGGTAGCGAGCCAGATAATTTCTTCTGGGTGGCGCTCGGTGGCCGCAAGCCTTACGACACAGACGCGGACTATCTCAACTATACGAGACTGTTCCGGTGCTCAAACGAGAAAGGATACTTTACAGTCTCCGAGAAATGTACGGACTTCTGTCAGGATGATTTGGCTGATGATGATATTATGATATTGGACAACGGAGAACAGGTCTTTCTGTGGCTTGGAGCAAAATGTTCTGAAGTGGAAATAAAGCTTGCATACAAATCTGCACAGGTGTATATACAACACATGAAAACCGTACAACCAGACCGTCCAAGGAAACTGTTTTTGACACTAAAAGACAAAGAGTCACGTCGGTTCACCAAGTGCTTCCATGGCTGGGGGGATCACAAGCGGCCTCCAGAATAA

Protein

MHYVTRLYRVHGAGNSIHLEPVAVRAASLDPRYVFVLDTGLIIYLWYGKKAKNTLKSKARLFAEKINKEERKNKAELIAEPPGKEPKSFWQILGHEEDVPFVPEEHVGEWSSRAVRLYRVELGMGYLELPQPGPAPLSRGALATRNVYILDAHLDVFVWFGKKSSRLVRAAAVKLAQELFNMVTRPPHALVTRLQEGTETQVFKTYFLGWDEIIAVDFTRTAESVARTGVDLASWAKQQETKADLSALFTPRQPAMTASEAKTLADEWNEDLEAMEAFVLEGRHFVRLPENELGVFYSCDCYVFLCRYVLCPDAEEESEGSNVDHETEDDGESATWVVYFWQGRRAPNMGWLTFTFGLERKFKQLCKRLEVVRTHQQQESLKFLSHFHRQFVLRDGKRNLKPEGRLPVELFELRSNGSALCTRLVQVKAEASQLNSAFCYILNVPLEGNGETSSAIVYAWIGSKSDPDSARLIEQMAEDKFNNPWVSLQVLTEGSEPDNFFWVALGGRKPYDTDADYLNYTRLFRCSNEKGYFTVSEKCTDFCQDDLADDDIMILDNGEQVFLWLGAKCSEVEIKLAYKSAQVYIQHMKTVQPDRPRKLFLTLKDKESRRFTKCFHGWGDHKRPPE

Similarity

Belongs to the villin/gelsolin family.

Keywords

Actin-binding   Complete proteome   Developmental protein   Leucine-rich repeat   Polymorphism   Reference proteome   Repeat  

Feature

chain  Protein flightless-1

Uniprot

H9J7M7   A0A2H1VL32   A0A3S2P2T9   A0A2A4J2P6   A0A212ENC8   A0A2A4IZ78   + More
A0A194PQD2   A0A2J7QXM2   A0A067QEP2   A0A2J7QXM9   A0A1Q3F6L5   A0A1Q3F6S0   E1ZXK9   E9ISY0   E2BLJ4   A0A151J2C3   A0A195F3I7   B0W2M9   A0A158NZT8   A0A0L7QXN2   A0A195BMH4   A0A026WPB4   A0A182H6N0   A0A151XBG4   Q17ED4   F4WIB9   A0A1S4F5U6   A0A195CNT6   A0A154P3I5   A0A084VD23   A0A182P0R8   A0A182UKK9   A0A182V9X0   A0A182WFQ2   A0A1B6C6V4   A0A2A3E9T0   A0A182Y6W2   A0A182NT12   A0A182IPJ9   A0A0L0BSJ3   A0A1B6I1P4   E0V9L7   A0A182RL00   A0A146KS58   D6X267   A0A182JQY9   T1P9T5   A0A336MYS3   A0A1I8MN70   A0A0A9X1H4   A0A0C9RME3   A0A310SQE9   W5JSG5   A0A0K8TKX2   A0A1I8NPL1   A0A1B0G1T6   A0A1Y1MHK3   K7IVH7   A0A0T6AZ13   A0A1A9VXJ4   A0A1L8DJ38   A0A1B0A7F4   A0A1A9Y669   A0A224XI49   A0A1J1J942   A0A0A1WWI1   A0A0K8TVK2   A0A1A9W9U5   A0A034WDM7   A0A0M9A185   A0A0P4VHI9   A0A088A2Y8   B4JIY5   B5DM61   B4L1L0   B4M353   J9JY79   B4GYE2   Q24020   B3NYD3   A0A0Q5TJ86   A0A1W4VVD9   B4I6G7   A0A3B0KM23   B3MWI7   A0A0R1EI52   B4PZ29   B4MSC1   A0A2H8TCW9   A0A2S2P6Q7   A0A226EEV5   A0A0P6FGJ4   A0A0P5N9H3   A0A0P6IBJ3   A0A0P6EZ46   A0A0P5VPY8   A0A0P6ARI5   A0A0P6EXZ2   A0A0P5ZVP3   A0A0P5TNY0  

Pubmed

19121390    22118469    26354079    24845553    20798317    21282665    + More
21347285    24508170    30249741    26483478    17510324    21719571    24438588    25244985    26108605    20566863    26823975    18362917    19820115    25315136    25401762    20920257    23761445    26369729    28004739    20075255    25830018    25348373    27129103    17994087    15632085    8248259    8582612    9520435    10731132    12537572    10731138    18057021    17550304   

EMBL

BABH01014058    BABH01014059    BABH01014060    BABH01014061    ODYU01003149    SOQ41533.1    + More
RSAL01000041    RVE50907.1    NWSH01003929    PCG65672.1    AGBW02013681    OWR42979.1    NWSH01005084    PCG64452.1    KQ459595    KPI95656.1    NEVH01009378    PNF33329.1    KK853751    KDQ85824.1    PNF33328.1    GFDL01011858    JAV23187.1    GFDL01011789    JAV23256.1    GL435066    EFN74092.1    GL765434    EFZ16387.1    GL449033    EFN83431.1    KQ980404    KYN16191.1    KQ981856    KYN34649.1    DS231827    EDS29337.1    ADTU01005002    ADTU01005003    KQ414704    KOC63357.1    KQ976440    KYM86486.1    KK107139    QOIP01000003    EZA57897.1    RLU25165.1    JXUM01114411    JXUM01114412    KQ565783    KXJ70670.1    KQ982330    KYQ57679.1    CH477283    EAT44842.1    GL888175    EGI66050.1    KQ977580    KYN01764.1    KQ434809    KZC06476.1    ATLV01011135    KE524643    KFB35867.1    GEDC01028164    JAS09134.1    KZ288322    PBC28234.1    JRES01001421    KNC23050.1    GECU01026858    JAS80848.1    DS234994    EEB10073.1    GDHC01019305    JAP99323.1    KQ971371    EFA10220.1    KA645516    AFP60145.1    UFQS01001564    UFQT01001564    SSX11461.1    SSX31028.1    GBHO01029745    JAG13859.1    GBYB01008151    GBYB01011973    JAG77918.1    JAG81740.1    KQ761039    OAD58387.1    ADMH02000297    ETN67066.1    GDAI01002817    JAI14786.1    CCAG010006899    GEZM01034411    JAV83815.1    LJIG01022475    KRT80377.1    GFDF01007699    JAV06385.1    GFTR01008707    JAW07719.1    CVRI01000072    CRL07521.1    GBXI01011437    JAD02855.1    GDHF01034011    GDHF01033377    GDHF01033369    GDHF01028190    GDHF01017032    GDHF01000295    JAI18303.1    JAI18937.1    JAI18945.1    JAI24124.1    JAI35282.1    JAI52019.1    GAKP01007059    JAC51893.1    KQ435767    KOX75280.1    GDKW01002650    JAI53945.1    CH916370    EDV99549.1    CH379064    EDY72578.1    CH933810    EDW07646.1    CH940651    EDW65228.2    ABLF02016317    CH479197    EDW27798.1    U01182    AF017777    AE014298    AF132184    CH954180    EDV47612.1    KQS30573.1    KQS30574.1    CH480823    EDW56373.1    OUUW01000011    SPP86886.1    CH902625    EDV34972.2    CM000162    KRK07105.1    EDX03090.1    CH963851    EDW75010.1    GFXV01000134    MBW11939.1    GGMR01012476    MBY25095.1    LNIX01000004    OXA56072.1    GDIQ01064587    JAN30150.1    GDIQ01145317    GDIQ01039705    JAL06409.1    GDIQ01006918    JAN87819.1    GDIQ01056541    JAN38196.1    GDIP01097075    JAM06640.1    GDIP01025550    JAM78165.1    GDIQ01056539    JAN38198.1    GDIP01037891    JAM65824.1    GDIP01124941    JAL78773.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053268    UP000235965    + More
UP000027135    UP000000311    UP000008237    UP000078492    UP000078541    UP000002320    UP000005205    UP000053825    UP000078540    UP000053097    UP000279307    UP000069940    UP000249989    UP000075809    UP000008820    UP000007755    UP000078542    UP000076502    UP000030765    UP000075885    UP000075902    UP000075903    UP000075920    UP000242457    UP000076408    UP000075884    UP000075880    UP000037069    UP000009046    UP000075900    UP000007266    UP000075881    UP000095301    UP000000673    UP000095300    UP000092444    UP000002358    UP000078200    UP000092445    UP000092443    UP000183832    UP000091820    UP000053105    UP000005203    UP000001070    UP000001819    UP000009192    UP000008792    UP000007819    UP000008744    UP000000803    UP000008711    UP000192221    UP000001292    UP000268350    UP000007801    UP000002282    UP000007798    UP000198287   

PRIDE

H9J7M7    Q24020   

Pfam

PF00626   Gelsolin        + More
PF00560   LRR_1
PF04281   Tom22
PF13855   LRR_8
PF12799   LRR_4
PF13516   LRR_6

Interpro

IPR007122   Villin/Gelsolin        + More
IPR032675   LRR_dom_sf       
IPR029919   FliI       
IPR001611   Leu-rich_rpt       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR005683   Tom22       
IPR007123   Gelsolin-like_dom       
IPR029006   ADF-H/Gelsolin-like_dom_sf       
IPR025875   Leu-rich_rpt_4       

Gene 3D

3.40.20.10     3.80.10.10    

ProteinModelPortal

H9J7M7   A0A2H1VL32   A0A3S2P2T9   A0A2A4J2P6   A0A212ENC8   A0A2A4IZ78   + More
A0A194PQD2   A0A2J7QXM2   A0A067QEP2   A0A2J7QXM9   A0A1Q3F6L5   A0A1Q3F6S0   E1ZXK9   E9ISY0   E2BLJ4   A0A151J2C3   A0A195F3I7   B0W2M9   A0A158NZT8   A0A0L7QXN2   A0A195BMH4   A0A026WPB4   A0A182H6N0   A0A151XBG4   Q17ED4   F4WIB9   A0A1S4F5U6   A0A195CNT6   A0A154P3I5   A0A084VD23   A0A182P0R8   A0A182UKK9   A0A182V9X0   A0A182WFQ2   A0A1B6C6V4   A0A2A3E9T0   A0A182Y6W2   A0A182NT12   A0A182IPJ9   A0A0L0BSJ3   A0A1B6I1P4   E0V9L7   A0A182RL00   A0A146KS58   D6X267   A0A182JQY9   T1P9T5   A0A336MYS3   A0A1I8MN70   A0A0A9X1H4   A0A0C9RME3   A0A310SQE9   W5JSG5   A0A0K8TKX2   A0A1I8NPL1   A0A1B0G1T6   A0A1Y1MHK3   K7IVH7   A0A0T6AZ13   A0A1A9VXJ4   A0A1L8DJ38   A0A1B0A7F4   A0A1A9Y669   A0A224XI49   A0A1J1J942   A0A0A1WWI1   A0A0K8TVK2   A0A1A9W9U5   A0A034WDM7   A0A0M9A185   A0A0P4VHI9   A0A088A2Y8   B4JIY5   B5DM61   B4L1L0   B4M353   J9JY79   B4GYE2   Q24020   B3NYD3   A0A0Q5TJ86   A0A1W4VVD9   B4I6G7   A0A3B0KM23   B3MWI7   A0A0R1EI52   B4PZ29   B4MSC1   A0A2H8TCW9   A0A2S2P6Q7   A0A226EEV5   A0A0P6FGJ4   A0A0P5N9H3   A0A0P6IBJ3   A0A0P6EZ46   A0A0P5VPY8   A0A0P6ARI5   A0A0P6EXZ2   A0A0P5ZVP3   A0A0P5TNY0  

PDB

3FFN     E-value=2.16783e-36,     Score=384

KEGG

101740804    no KO assigned | (RefSeq) gelsolin; protein flightless-1

GO

GO:0051015   GO:0006886   GO:0051014   GO:0005741   GO:0030036   GO:0004721   GO:0010004   GO:0030239   GO:0007527   GO:0005509   GO:0003779   GO:0005515   GO:0005634   GO:0008033   GO:0009058   GO:0005089   GO:0035023   GO:0016742   GO:0003824  

PANTHER

PTHR11977   PTHR11977:SF92  

Length:

626

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.6128

Exp number, first 60 AAs:

1.60843

Total prob of N-in:

0.09555

outside

1  -  626

 

 

Pi

226.828743

Theta

158.817938

Tajima's D

-2.646282

CLR

1172.589524

CSRT

0.000149992500374981

Interpretation

Possibly Positive selection