Gene

KWMTBOMO04669  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005519

Annotation

PREDICTED:_protein_flightless-1_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr8(+):11895379-11904466      View in EpiBrowser

Full name

Protein flightless-1      

Alternative Name

Flightless-I

Location in the cell

Cytoplasmic   Reliability : 1.495 Nuclear   Reliability : 1.922

CDS

ATGGCAAATACAGGCTTATTGCCGTTTGTGCGGGGAGTTGATTTCACGTGTAACGATTTCAGCGACGATAAATTTCCTGATGCTATTCGCTATATGACTGGATTGCAATGGTTGAGACTCGACAAGACAAACCTTTGTGATATACCTGAAGAACTAGGAAAGTTAATGAAATTGGAAAACCTTTCCTTGAAAAAGAACAATCTAGAAAAGTTATTTGGTGAACTCACAGAGTTAAAGTGTTTGAGATCTCTGAATGTCAGGCACAACAAGGTGAAGACTTCTGGGATCCCGGCTGAACTTTTCCATCTAGAAGAACTCACTACCTTAGATCTGTCACATAATAGGTTAAAGGAAGTCCCTGAGGGGTTGGAGAAAGCTAAATCTTTACTTGTATTGAACCTCAGCCATAACAGAATTGAAACAATCCCACCAACTTTATTTGTCCAACTAACTGACTTATTATTTCTGGATCTATCTCATAATCTTTTGGAGACCCTACCCCCTCAGACTAGAAGGTTGGCAAACCTGCAGACTTTGATACTCAATGATAATCCACTTGGAGTTTTCCAGTTGAGGCAATTACCTTCACTTCAAAGTCTAGAGACACTGCATATGCGAAACACACAAAGAACTCTTGCCAATTTGCCGACATCATTGGAAACACTCTCAAATCTTTCCGATGTGGACTTATCAAAGAATGCATTAACGAAAATACCAGATGCCTTGTACACGTTGTTGAGTCTCAAAAGACTGAATCTTAGTGATAATGAAATCTCGGAATTGTCTGCAGCAATGGATACATGGCAGAAACTAGAGAGCTTAAATTTGTCAAGAAACAATCTGACATCACTTCCGGCGTCTTTATGTAAGCTGCAGAACTTAAGGAGGTTACATGTAGACGACAATAAACTTGACTTTGAAGGCATACCATCTGGAATTGGGAAACTTGGCGCTTTGGAAGTATTCTCAGCTGCTAATAATTTACTGGAGATGATACCGGAAGGATTGTGTAGATGTGGCGCGCTAAAAAAGTTGAATCTGAGTTGCAATAAGCTGATCACTCTCCCCGACGCCGTTCACCTTCTAAGCGATCTGGAAAGTCTTCAGCTTCACGGAAACCCTGATCTCGTAATGCCTCCGAAGCCCGTCGAAAGACCAAGGGGAGCTGGCTTGCAGTATTACAACATTGACTTCTCGTTGCAAGCTCAGCTTCAACTGGCCGGGGCTGCGTCAGCTGAAAGCACAACAACCAGCAGCGTTAAGTCGGATCCGATAGCTCGCAAGCTCCGCCTACGTCGCGGCCGGCCCGAGCCCGAGCAGAAGGACTCGGCGCTGATCCTGCGCGGCATGCAGGAGCAAGCCAACACGCAGCACGGCGACAACGTGCTCGACCAACGACACAGCGAACTCAAACCAAAACGCTGGGACGAAAGCTTAGAGAAGCCCCCGCTAGACTATTCGGAGTTCTTCGACGAAGACACGGGTCAAACTCCTGGACTACAGGTGTGGGAGATCGAGAACTTCATACCGGCTCCTGTTGATGAGGTCGCTCACGGGAAATTCTTCGAAGGTGATTGCTACATCGTGCTGAAGACAGCCGTGGAAGAGCAAGGACAGCTGTCATGGGACATACACTTTTGGATCGGATCCAAAGCTACTTTAGACAAGGGGGCCTGCGCCGCAATGCACGCCGTTAACCTACGCAACCTGCTGGGAGCCAAGCGCACGCGGCGCCACGAGCAGGGCGACGAGAGCCCCGAGTTCATGGCGCTGTTCCCCACCCCGCCGGTCTACATCCAGGGCAGCCACACTCCGTCAGGGTTCTTCACGGTCGACGACCCGGATGAAGATTTCTTTTAA

Protein

MANTGLLPFVRGVDFTCNDFSDDKFPDAIRYMTGLQWLRLDKTNLCDIPEELGKLMKLENLSLKKNNLEKLFGELTELKCLRSLNVRHNKVKTSGIPAELFHLEELTTLDLSHNRLKEVPEGLEKAKSLLVLNLSHNRIETIPPTLFVQLTDLLFLDLSHNLLETLPPQTRRLANLQTLILNDNPLGVFQLRQLPSLQSLETLHMRNTQRTLANLPTSLETLSNLSDVDLSKNALTKIPDALYTLLSLKRLNLSDNEISELSAAMDTWQKLESLNLSRNNLTSLPASLCKLQNLRRLHVDDNKLDFEGIPSGIGKLGALEVFSAANNLLEMIPEGLCRCGALKKLNLSCNKLITLPDAVHLLSDLESLQLHGNPDLVMPPKPVERPRGAGLQYYNIDFSLQAQLQLAGAASAESTTTSSVKSDPIARKLRLRRGRPEPEQKDSALILRGMQEQANTQHGDNVLDQRHSELKPKRWDESLEKPPLDYSEFFDEDTGQTPGLQVWEIENFIPAPVDEVAHGKFFEGDCYIVLKTAVEEQGQLSWDIHFWIGSKATLDKGACAAMHAVNLRNLLGAKRTRRHEQGDESPEFMALFPTPPVYIQGSHTPSGFFTVDDPDEDFF

Similarity

Belongs to the villin/gelsolin family.

Keywords

Actin-binding   Complete proteome   Developmental protein   Leucine-rich repeat   Polymorphism   Reference proteome   Repeat  

Feature

chain  Protein flightless-1

Uniprot

H9J7M7   A0A3S2P2T9   A0A212ENC8   A0A194QSY4   A0A194PWZ1   A0A2H1WNX3   + More
A0A0K8S910   A0A146KS58   A0A1Q3F6L5   A0A1Q3F6S0   A0A1S4F5U6   Q17ED4   A0A182H6N0   A0A182GI72   D6X267   B0W2M9   E1ZXK9   A0A224XI49   A0A0C9RME3   E9ISY0   A0A1I8MN70   A0A182Q6Y3   A0A1B6FFE0   A0A151J2C3   A0A182NT12   F4WIB9   A0A026WPB4   E2BLJ4   A0A182IPJ9   A0A067QEP2   A0A158NZT8   A0A182P0R8   A0A195CNT6   A0A182RL00   A0A2M4AEU0   W5JSG5   A0A2J7QXM2   A0A195F3I7   A0A2A3E9T0   A0A195BMH4   A0A182JQY9   A0A182LY85   A0A084VD23   A0A182V9X0   A0A0L0BSJ3   A0A182LHF4   Q7QHP7   A0A182HY97   A0A182WYT6   A0A182WFQ2   A0A1L8DJ38   A0A182FLL2   W8BIH1   E0V9L7   A0A034WDM7   A0A1B0A7F4   A0A1B0G1T6   A0A1Y1MDJ9   A0A2R7WXH0   U4U0V8   A0A2R7WWP2   A0A0A1WWI1   A0A1Y1MHK3   K7IVH7   A0A0L7QXN2   A0A0K8TVK2   A0A154P3I5   A0A1A9W9U5   A0A1I8NPL1   A0A0M9A185   A0A1D2MSH9   B3MWI7   A0A1W4VVD9   B3NYD3   A0A1B6G105   A0A0R1EIY6   B4PZ29   Q24020   B5DM61   A0A2M4B9Y3   B4NUV2   A0A182Y6W2   A0A336MYS3   B4M353   A0A3B0JXU0   A0A3B0KM23   B4MSC1   A0A182UKK9   B4L1L0   A0A0M4EIN0   B4JIY5   T1P9T5   A0A151XBG4   A0A1J1J942   A0A310SQE9   A0A1A9VXJ4   A0A0Q5TJ86   A0A0R1EI52   A0A1A9Y669   A0A0J7L0S9  

Pubmed

19121390    22118469    26354079    26823975    17510324    26483478    + More
18362917    19820115    20798317    21282665    25315136    21719571    24508170    30249741    24845553    21347285    20920257    23761445    24438588    26108605    20966253    12364791    14747013    17210077    24495485    20566863    25348373    28004739    23537049    25830018    20075255    27289101    17994087    17550304    8248259    8582612    9520435    10731132    12537572    10731138    15632085    25244985    18057021   

EMBL

BABH01014058    BABH01014059    BABH01014060    BABH01014061    RSAL01000041    RVE50907.1    + More
AGBW02013681    OWR42979.1    KQ461154    KPJ08582.1    KQ459595    KPI95655.1    ODYU01009991    SOQ54771.1    GBRD01016058    JAG49768.1    GDHC01019305    JAP99323.1    GFDL01011858    JAV23187.1    GFDL01011789    JAV23256.1    CH477283    EAT44842.1    JXUM01114411    JXUM01114412    KQ565783    KXJ70670.1    JXUM01065660    KQ562359    KXJ76068.1    KQ971371    EFA10220.1    DS231827    EDS29337.1    GL435066    EFN74092.1    GFTR01008707    JAW07719.1    GBYB01008151    GBYB01011973    JAG77918.1    JAG81740.1    GL765434    EFZ16387.1    AXCN02002653    GECZ01020840    JAS48929.1    KQ980404    KYN16191.1    GL888175    EGI66050.1    KK107139    QOIP01000003    EZA57897.1    RLU25165.1    GL449033    EFN83431.1    KK853751    KDQ85824.1    ADTU01005002    ADTU01005003    KQ977580    KYN01764.1    GGFK01005974    MBW39295.1    ADMH02000297    ETN67066.1    NEVH01009378    PNF33329.1    KQ981856    KYN34649.1    KZ288322    PBC28234.1    KQ976440    KYM86486.1    AXCM01009604    ATLV01011135    KE524643    KFB35867.1    JRES01001421    KNC23050.1    AAAB01008816    EAA05158.4    APCN01004510    GFDF01007699    JAV06385.1    GAMC01013494    JAB93061.1    DS234994    EEB10073.1    GAKP01007059    JAC51893.1    CCAG010006899    GEZM01034412    JAV83814.1    KK855776    PTY23860.1    KB631761    ERL85908.1    PTY23861.1    GBXI01011437    JAD02855.1    GEZM01034411    JAV83815.1    KQ414704    KOC63357.1    GDHF01034011    GDHF01033377    GDHF01033369    GDHF01028190    GDHF01017032    GDHF01000295    JAI18303.1    JAI18937.1    JAI18945.1    JAI24124.1    JAI35282.1    JAI52019.1    KQ434809    KZC06476.1    KQ435767    KOX75280.1    LJIJ01000614    ODM95848.1    CH902625    EDV34972.2    CH954180    EDV47612.1    GECZ01013640    JAS56129.1    CM000162    KRK07106.1    EDX03090.1    U01182    AF017777    AE014298    AF132184    CH379064    EDY72578.1    GGFJ01000689    MBW49830.1    CH984282    EDX16385.1    UFQS01001564    UFQT01001564    SSX11461.1    SSX31028.1    CH940651    EDW65228.2    OUUW01000011    SPP86887.1    SPP86886.1    CH963851    EDW75010.1    CH933810    EDW07646.1    CP012528    ALC48791.1    CH916370    EDV99549.1    KA645516    AFP60145.1    KQ982330    KYQ57679.1    CVRI01000072    CRL07521.1    KQ761039    OAD58387.1    KQS30573.1    KQS30574.1    KRK07105.1    LBMM01001484    KMQ96236.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000053240    UP000053268    UP000008820    + More
UP000069940    UP000249989    UP000007266    UP000002320    UP000000311    UP000095301    UP000075886    UP000078492    UP000075884    UP000007755    UP000053097    UP000279307    UP000008237    UP000075880    UP000027135    UP000005205    UP000075885    UP000078542    UP000075900    UP000000673    UP000235965    UP000078541    UP000242457    UP000078540    UP000075881    UP000075883    UP000030765    UP000075903    UP000037069    UP000075882    UP000007062    UP000075840    UP000076407    UP000075920    UP000069272    UP000009046    UP000092445    UP000092444    UP000030742    UP000002358    UP000053825    UP000076502    UP000091820    UP000095300    UP000053105    UP000094527    UP000007801    UP000192221    UP000008711    UP000002282    UP000000803    UP000001819    UP000000304    UP000076408    UP000008792    UP000268350    UP000007798    UP000075902    UP000009192    UP000092553    UP000001070    UP000075809    UP000183832    UP000078200    UP000092443    UP000036403   

PRIDE

H9J7M7    Q24020   

Pfam

PF00626   Gelsolin        + More
PF00560   LRR_1
PF04281   Tom22
PF13855   LRR_8
PF12799   LRR_4
PF13516   LRR_6

Interpro

IPR007122   Villin/Gelsolin        + More
IPR032675   LRR_dom_sf       
IPR029919   FliI       
IPR001611   Leu-rich_rpt       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR005683   Tom22       
IPR007123   Gelsolin-like_dom       
IPR029006   ADF-H/Gelsolin-like_dom_sf       
IPR025875   Leu-rich_rpt_4       

Gene 3D

3.40.20.10     3.80.10.10    

ProteinModelPortal

H9J7M7   A0A3S2P2T9   A0A212ENC8   A0A194QSY4   A0A194PWZ1   A0A2H1WNX3   + More
A0A0K8S910   A0A146KS58   A0A1Q3F6L5   A0A1Q3F6S0   A0A1S4F5U6   Q17ED4   A0A182H6N0   A0A182GI72   D6X267   B0W2M9   E1ZXK9   A0A224XI49   A0A0C9RME3   E9ISY0   A0A1I8MN70   A0A182Q6Y3   A0A1B6FFE0   A0A151J2C3   A0A182NT12   F4WIB9   A0A026WPB4   E2BLJ4   A0A182IPJ9   A0A067QEP2   A0A158NZT8   A0A182P0R8   A0A195CNT6   A0A182RL00   A0A2M4AEU0   W5JSG5   A0A2J7QXM2   A0A195F3I7   A0A2A3E9T0   A0A195BMH4   A0A182JQY9   A0A182LY85   A0A084VD23   A0A182V9X0   A0A0L0BSJ3   A0A182LHF4   Q7QHP7   A0A182HY97   A0A182WYT6   A0A182WFQ2   A0A1L8DJ38   A0A182FLL2   W8BIH1   E0V9L7   A0A034WDM7   A0A1B0A7F4   A0A1B0G1T6   A0A1Y1MDJ9   A0A2R7WXH0   U4U0V8   A0A2R7WWP2   A0A0A1WWI1   A0A1Y1MHK3   K7IVH7   A0A0L7QXN2   A0A0K8TVK2   A0A154P3I5   A0A1A9W9U5   A0A1I8NPL1   A0A0M9A185   A0A1D2MSH9   B3MWI7   A0A1W4VVD9   B3NYD3   A0A1B6G105   A0A0R1EIY6   B4PZ29   Q24020   B5DM61   A0A2M4B9Y3   B4NUV2   A0A182Y6W2   A0A336MYS3   B4M353   A0A3B0JXU0   A0A3B0KM23   B4MSC1   A0A182UKK9   B4L1L0   A0A0M4EIN0   B4JIY5   T1P9T5   A0A151XBG4   A0A1J1J942   A0A310SQE9   A0A1A9VXJ4   A0A0Q5TJ86   A0A0R1EI52   A0A1A9Y669   A0A0J7L0S9  

PDB

4U08     E-value=2.29176e-27,     Score=306

KEGG

101740804    no KO assigned | (RefSeq) gelsolin; protein flightless-1

GO

GO:0051015   GO:0006886   GO:0051014   GO:0005741   GO:0030036   GO:0004721   GO:0010004   GO:0007527   GO:0030239   GO:0005509   GO:0003779   GO:0005515   GO:0005634   GO:0008033   GO:0009058   GO:0005089   GO:0035023   GO:0016742   GO:0003824  

PANTHER

PTHR11977   PTHR11977:SF92  

Length:

619

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00126

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00008

outside

1  -  619

 

 

Pi

229.696124

Theta

204.579035

Tajima's D

-1.34781

CLR

0.748006

CSRT

0.0833458327083646

Interpretation

Uncertain