Gene

KWMTBOMO04647

Annotation

G_protein-coupled_receptor_[Danaus_plexippus]

Location

Bomo_Chr8(+):11396761-11403901      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.021

CDS

ATGATTTCCTTAAATCTCACAGATTTCAAAAGTGAACTGCTGTATTTCTACCCTTCAGTACTTACCTTAGTTGTTGTAAACGTAATTCTTTTCTCCGTGACGGCGTATCGTATTAGATCTATCCGACAAGAAACAGCTATTTTAAAGGGATCTGAATCTTCGAGGAGTGATAAATTGAAAAAAGATAAGCAAAGGTATTCTTTATACTTGAAATTGTTTGTCGTTATGGGTGTGAATTGGACAATCGAGGTGATAGGCTTCGCAGTCGGCGGATCTAACTACTACTGGATTCTTATAGACATATCGAATATCGGGCTTGGAATCTTCATATTTTTAATATTCGTTTGGAAAAAGAAAGTCAGAAACCTAATAAGGAAAAGATTTCAACAAATCCGAGGTCAACGTGTTTCTTCTGACGGACCAGGAATAAAGTGGACCACCAGCTCTGCACCCACAGAGGACACACGCGTATCGGGCGACGAATCCCTGATAAGATTAAAGGAATTGCGTTAG

Protein

MISLNLTDFKSELLYFYPSVLTLVVVNVILFSVTAYRIRSIRQETAILKGSESSRSDKLKKDKQRYSLYLKLFVVMGVNWTIEVIGFAVGGSNYYWILIDISNIGLGIFIFLIFVWKKKVRNLIRKRFQQIRGQRVSSDGPGIKWTTSSAPTEDTRVSGDESLIRLKELR

Similarity

Belongs to the G-protein coupled receptor Fz/Smo family.

Uniprot

A0A212FD97   A0A1E1WCB0   A0A194QSV3   A0A194PWW7   A0A1E1WN64   A0A1E1WH08   + More
A0A2R7VRT9   A0A182N959   A0A194PX16   A0A194QT14   A0A182PLA5   A0A067QSF7   A0A182IYC9   A0A1Y1L4G2   A0A1J1II64   A0A1L8DJU0   A0A1L8DK28   A0A2M4CFX2   A0A2M4CG55   A0A1Y1L8A2   A0A2P8Z835   A0A2M4AQA6   A0A182SZW2   B0X3X1   A0A1Q3FLM5   A0A1B6M8D2   A0A182V7J0   A0A2Y9D3K1   A0A182I170   A0A1B6F3W1   W5JEH1   A0A2M4DP26   A0A182LLL3   A0A182THK7   A0A2Y9D3T7   A7UU57   A0A182V1K9   A0A182N958   A0A182FDT7   A0A139W969   A0A2H1W4J5   A0A1Y1NCH2   A0A1B6EGM6   A0A167L5U9   A0A2Z5H045   A0A2Z5H083   A0A1Y1NFN1   A0A1B6CU80   E0VM50   A0A1B6E0C8   K7JQP3   A0A1Y1NE70   A0A1B6DQS8   A0A195CCU5   V9LVR6   A0A3S2LCX1   J7ETA9   A0A1Y1NEU4   A0A1Y1NI84  

Pubmed

22118469    26354079    24845553    28004739    29403074    20920257    + More
23761445    20966253    12364791    14747013    17210077    18362917    19820115    20566863    20075255   

EMBL

AGBW02009085    OWR51711.1    GDQN01006455    JAT84599.1    KQ461154    KPJ08557.1    + More
KQ459595    KPI95630.1    GDQN01002620    JAT88434.1    GDQN01004782    JAT86272.1    KK854040    PTY10069.1    KPI95685.1    KPJ08612.1    KK853008    KDR12560.1    GEZM01065042    JAV68579.1    CVRI01000050    CRK99458.1    GFDF01007356    JAV06728.1    GFDF01007357    JAV06727.1    GGFL01000036    MBW64214.1    GGFL01000037    MBW64215.1    GEZM01065041    JAV68580.1    PYGN01000153    PSN52656.1    GGFK01009643    MBW42964.1    DS232324    EDS40048.1    GFDL01006627    JAV28418.1    GEBQ01007873    JAT32104.1    APCN01000032    GECZ01024998    JAS44771.1    ADMH02001746    ETN61224.1    GGFL01015103    MBW79281.1    AAAB01008960    EDO63835.1    KQ972625    KXZ75833.1    ODYU01006156    SOQ47762.1    GEZM01010671    JAV93926.1    GEDC01000202    JAS37096.1    KU363815    ANB32480.1    MH175213    AXC32921.1    MH175214    AXC32922.1    GEZM01007070    JAV95425.1    GEDC01020320    JAS16978.1    DS235289    EEB14456.1    GEDC01018212    GEDC01005937    GEDC01001428    JAS19086.1    JAS31361.1    JAS35870.1    GEZM01010670    JAV93927.1    GEDC01018773    GEDC01009262    GEDC01000043    JAS18525.1    JAS28036.1    JAS37255.1    KQ978023    KYM98041.1    JQ809653    AFW03960.1    RSAL01000041    RVE50936.1    HQ188200    AEM43035.1    GEZM01007068    JAV95430.1    GEZM01007069    JAV95427.1   

Proteomes

UP000007151    UP000053240    UP000053268    UP000075884    UP000075885    UP000027135    + More
UP000075880    UP000183832    UP000245037    UP000075901    UP000002320    UP000075903    UP000076407    UP000075840    UP000000673    UP000075882    UP000075902    UP000007062    UP000069272    UP000007266    UP000009046    UP000002358    UP000078542    UP000283053    UP000005203   

Pfam

PF00002   7tm_2        + More
PF06652   Methuselah_N
PF07666   MpPF26
PF05773   RWD
PF01534   Frizzled

Interpro

IPR036272   Methuselah_N_sf        + More
IPR000832   GPCR_2_secretin-like       
IPR017981   GPCR_2-like       
IPR010596   Methuselah_N_dom       
IPR011655   MpPF26       
IPR013083   Znf_RING/FYVE/PHD       
IPR016135   UBQ-conjugating_enzyme/RWD       
IPR001841   Znf_RING       
IPR006575   RWD-domain       
IPR000539   Frizzled/Smoothened_TM       
IPR023311   Methusela_ecto_dom_2       
IPR017452   GPCR_Rhodpsn_7TM       

SUPFAM

SSF63877   SSF63877        + More
SSF54495   SSF54495       

Gene 3D

3.10.110.10     3.30.40.10     2.170.180.11    

CDD

cd00251  Mth_Ecto

ProteinModelPortal

A0A212FD97   A0A1E1WCB0   A0A194QSV3   A0A194PWW7   A0A1E1WN64   A0A1E1WH08   + More
A0A2R7VRT9   A0A182N959   A0A194PX16   A0A194QT14   A0A182PLA5   A0A067QSF7   A0A182IYC9   A0A1Y1L4G2   A0A1J1II64   A0A1L8DJU0   A0A1L8DK28   A0A2M4CFX2   A0A2M4CG55   A0A1Y1L8A2   A0A2P8Z835   A0A2M4AQA6   A0A182SZW2   B0X3X1   A0A1Q3FLM5   A0A1B6M8D2   A0A182V7J0   A0A2Y9D3K1   A0A182I170   A0A1B6F3W1   W5JEH1   A0A2M4DP26   A0A182LLL3   A0A182THK7   A0A2Y9D3T7   A7UU57   A0A182V1K9   A0A182N958   A0A182FDT7   A0A139W969   A0A2H1W4J5   A0A1Y1NCH2   A0A1B6EGM6   A0A167L5U9   A0A2Z5H045   A0A2Z5H083   A0A1Y1NFN1   A0A1B6CU80   E0VM50   A0A1B6E0C8   K7JQP3   A0A1Y1NE70   A0A1B6DQS8   A0A195CCU5   V9LVR6   A0A3S2LCX1   J7ETA9   A0A1Y1NEU4   A0A1Y1NI84  

KEGG

101737554    K04599 G protein-coupled receptor Mth (Methuselah protein) | (RefSeq) G-protein coupled receptor Mth

GO

GO:0007166   GO:0004930   GO:0016021   GO:0004888  

Length:

170

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

67.17359

Exp number, first 60 AAs:

21.59334

Total prob of N-in:

0.00018

POSSIBLE N-term signal

sequence

outside

1  -  12

TMhelix

13  -  35

inside

36  -  67

TMhelix

68  -  90

outside

91  -  93

TMhelix

94  -  116

inside

117  -  170

 

 

Pi

129.850654

Theta

152.014715

Tajima's D

-0.5207

CLR

106.826291

CSRT

0.245887705614719

Interpretation

Uncertain