Gene

KWMTBOMO04622

Annotation

PREDICTED:_cytochrome_c_oxidase_assembly_protein_COX19_[Amyelois_transitella]

Location

Bomo_Chr8(+):10774287-10774853      View in EpiBrowser

Full name

Cytochrome c oxidase assembly protein COX19      

Location in the cell

Nuclear   Reliability : 2.363

CDS

ATGTCAACTGCTATGACTTTCGGCCAGAAACAATTTATTCCAACTCCACCAGATAAGGGAAGTTTTCCCTTGGATCACGAAGGAATTTGCAAGAAAACTATGGTTCGCTACATGAAATGTTTGATTAATAACAATAGCAATAACTCATTATGTCGTGATGAAGCTAAGGAATATTTGGCATGTAGAATGGAGAATAATTTAATGGCTAAAGAAGACTGGAATAATTTAGGTTTTCAAGAAAATAAAGAAGAGCGATAG

Protein

MSTAMTFGQKQFIPTPPDKGSFPLDHEGICKKTMVRYMKCLINNNSNNSLCRDEAKEYLACRMENNLMAKEDWNNLGFQENKEER

Description

Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis. May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity).

Subunit

Interacts with CHCHD4/MIA40 forming transient intermolecular disulfide bridges.

Similarity

Belongs to the COX19 family.

Keywords

Acetylation   Complete proteome   Cytoplasm   Disulfide bond   Mitochondrion   Reference proteome  

Feature

chain  Cytochrome c oxidase assembly protein COX19

Uniprot

A0A194PWU8   A0A0L7LSZ5   S4PTT0   A0A2H1V0J8   A0A212EYW9   A0A2P8YJK4   + More
A0A1L8E052   A0A1L8E0M6   A0A2A3EG67   V9IEZ3   A0A0M9A1G6   A0A067QJ95   A0A026W370   F4WEP9   A0A087ZPP7   A0A151IPW2   A0A1Q3FJI2   A0A195FKY1   N6UGE8   Q16MI0   A0A195E7V7   E2BGX5   A0A1Q3FJX8   A0A023EDW3   A0A023ECC4   A0A1Q3FJQ9   A0A0L7R177   A0A182GLL1   A0A087UJ75   K7IS02   E2A2R8   A0A1S4ET34   B0XL27   A0A158NET7   A0A154PMQ6   A0A232FM10   A0A182KBI2   T1GMG5   A0A1Q3FK16   A0A182W254   A0A1W4VD55   A0A1Q3FKQ4   A0A182RMQ4   A0A1S4HD39   A0A0Q9WPN2   A0A182N9P7   B5E0I4   B4GHG9   A0A0M4EDH8   A0A1I8M4V6   A0A084W4E1   V5I3E5   A0A0J7L3W2   A0A2M4C4S5   B3NN05   B4I7U8   B4NVS3   B4P8U6   E1JGR4   T1DNK0   A0A2M3ZCY4   A0A2M4AZU2   A0A2M4C4S3   A0A336MTA4   A0A2M4AZ68   A0A336K641   B3MIZ2   A0A182MV92   A0A2P6L072   A0A2M4CXM6   A0A182YBQ1   A0A2M4CXU5   F7DGF4   A0A182PK93   W5JRK2   A0A0L8I5F4   A0A3S3SME1   A0A1I8P8R3   A0A369RTD1   B3SDQ3   T1IHP2   A0A287AQK8   A0A286XB29   A0A2Y9F571   F6U101   A0A182UHM3   A0A2Y9E2I0   D3ZIS5   A8E4L1   A0A287DBD1   A0A0P6K2Z3   A0A132AIX8   A0A250XUW7   A0A182FVS7   A0A1L8EQC5   A0A340Y5Y3   A0A1S3FQV1   A0A1W0XBM6   G3SV53   A0A3B4D5X0  

Pubmed

26354079    26227816    23622113    22118469    29403074    24845553    + More
24508170    30249741    21719571    23537049    17510324    20798317    24945155    26483478    20075255    21347285    28648823    17994087    15632085    25315136    24438588    25765539    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25244985    20431018    20920257    23761445    30042472    18719581    21993624    19892987    15057822    15632090    26555130    28087693    27762356   

EMBL

KQ459595    KPI95610.1    JTDY01000150    KOB78585.1    GAIX01011503    JAA81057.1    + More
ODYU01000113    SOQ34339.1    AGBW02011442    OWR46651.1    PYGN01000552    PSN44384.1    GFDF01001961    JAV12123.1    GFDF01001962    JAV12122.1    KZ288254    PBC30708.1    JR042889    AEY59683.1    KQ435763    KOX75400.1    KK853297    KDR08782.1    KK107455    QOIP01000010    EZA50517.1    RLU17363.1    GL888103    EGI67412.1    KQ976806    KYN08202.1    GFDL01007357    JAV27688.1    KQ981490    KYN41325.1    APGK01026886    KB740648    ENN79716.1    CH477861    CH477658    EAT35536.1    EAT37681.1    EAT37683.1    KQ979479    KYN21300.1    GL448228    EFN85107.1    GFDL01007114    JAV27931.1    GAPW01006627    JAC06971.1    GAPW01006626    JAC06972.1    GFDL01007236    JAV27809.1    KQ414668    KOC64598.1    JXUM01072257    KQ562711    KXJ75283.1    KK120053    KFM77414.1    GL436210    EFN72272.1    DS234212    EDS33256.1    ADTU01013669    KQ434988    KZC13165.1    NNAY01000055    OXU31488.1    CAQQ02172840    GFDL01007203    JAV27842.1    GFDL01006953    JAV28092.1    CH963850    KRF98164.1    CM000071    EDY69355.1    CH479183    EDW35939.1    CP012524    ALC41038.1    ATLV01020327    KE525298    KFB45085.1    GANP01000196    JAB84272.1    LBMM01000896    KMQ97258.1    GGFJ01011000    MBW60141.1    CH954179    EDV55499.1    CH480824    EDW56673.1    CM000362    CH989425    CM002911    EDX08115.1    EDX16166.1    KMY95628.1    CM000158    EDW91200.1    AE013599    AY102691    ACZ94515.1    AGK45256.1    GAMD01002800    JAA98790.1    GGFM01005608    MBW26359.1    GGFK01012767    MBW46088.1    GGFJ01011169    MBW60310.1    UFQS01001716    UFQT01001716    SSX11950.1    SSX31497.1    GGFK01012768    MBW46089.1    UFQS01000062    UFQT01000062    SSW98815.1    SSX19201.1    CH902619    EDV37058.1    AXCM01001643    MWRG01003010    PRD31966.1    GGFL01005908    MBW70086.1    GGFL01005907    MBW70085.1    AAMC01119007    ADMH02000674    ETN65374.1    KQ416499    KOF96738.1    NCKU01000294    RWS16116.1    NOWV01000205    RDD37938.1    DS985284    EDV19137.1    JH429957    AEMK02000013    AAKN02032234    AC127903    CH474012    EDL89773.1    BC134520    AGTP01103410    GEBF01004792    JAN98840.1    JXLN01015946    KPM10877.1    GFFV01004856    JAV35089.1    CM004483    OCT61553.1    MTYJ01000004    OQV24915.1   

Proteomes

UP000053268    UP000037510    UP000007151    UP000245037    UP000242457    UP000053105    + More
UP000027135    UP000053097    UP000279307    UP000007755    UP000005203    UP000078542    UP000078541    UP000019118    UP000008820    UP000078492    UP000008237    UP000053825    UP000069940    UP000249989    UP000054359    UP000002358    UP000000311    UP000079169    UP000002320    UP000005205    UP000076502    UP000215335    UP000075881    UP000015102    UP000075920    UP000192221    UP000075900    UP000007798    UP000075884    UP000001819    UP000008744    UP000092553    UP000095301    UP000030765    UP000036403    UP000008711    UP000001292    UP000000304    UP000002282    UP000000803    UP000007801    UP000075883    UP000076408    UP000008143    UP000075885    UP000000673    UP000053454    UP000285301    UP000095300    UP000253843    UP000009022    UP000008227    UP000005447    UP000248484    UP000002281    UP000075902    UP000248480    UP000002494    UP000009136    UP000005215    UP000069272    UP000186698    UP000265300    UP000081671    UP000007646    UP000261440   

PRIDE

D3ZIS5    A8E4L1   

Pfam

PF06747   CHCH        + More
PF02441   Flavoprotein
PF05676   NDUF_B7
PF18036   Ubiquitin_4
PF07896   DUF1674

Interpro

IPR010625   CHCH        + More
IPR009069   Cys_alpha_HP_mot_SF       
IPR036551   Flavin_trans-like       
IPR003382   Flavoprotein       
IPR008698   NADH_UbQ_OxRdtase_B18_su       
IPR040610   SNRNP25_ubiquitin       
IPR012875   SDHF4       
IPR029071   Ubiquitin-like_domsf       
IPR039690   SNRNP25       

SUPFAM

SSF47072   SSF47072        + More
SSF52507   SSF52507       
SSF54236   SSF54236       

Gene 3D

3.40.50.1950    

ProteinModelPortal

A0A194PWU8   A0A0L7LSZ5   S4PTT0   A0A2H1V0J8   A0A212EYW9   A0A2P8YJK4   + More
A0A1L8E052   A0A1L8E0M6   A0A2A3EG67   V9IEZ3   A0A0M9A1G6   A0A067QJ95   A0A026W370   F4WEP9   A0A087ZPP7   A0A151IPW2   A0A1Q3FJI2   A0A195FKY1   N6UGE8   Q16MI0   A0A195E7V7   E2BGX5   A0A1Q3FJX8   A0A023EDW3   A0A023ECC4   A0A1Q3FJQ9   A0A0L7R177   A0A182GLL1   A0A087UJ75   K7IS02   E2A2R8   A0A1S4ET34   B0XL27   A0A158NET7   A0A154PMQ6   A0A232FM10   A0A182KBI2   T1GMG5   A0A1Q3FK16   A0A182W254   A0A1W4VD55   A0A1Q3FKQ4   A0A182RMQ4   A0A1S4HD39   A0A0Q9WPN2   A0A182N9P7   B5E0I4   B4GHG9   A0A0M4EDH8   A0A1I8M4V6   A0A084W4E1   V5I3E5   A0A0J7L3W2   A0A2M4C4S5   B3NN05   B4I7U8   B4NVS3   B4P8U6   E1JGR4   T1DNK0   A0A2M3ZCY4   A0A2M4AZU2   A0A2M4C4S3   A0A336MTA4   A0A2M4AZ68   A0A336K641   B3MIZ2   A0A182MV92   A0A2P6L072   A0A2M4CXM6   A0A182YBQ1   A0A2M4CXU5   F7DGF4   A0A182PK93   W5JRK2   A0A0L8I5F4   A0A3S3SME1   A0A1I8P8R3   A0A369RTD1   B3SDQ3   T1IHP2   A0A287AQK8   A0A286XB29   A0A2Y9F571   F6U101   A0A182UHM3   A0A2Y9E2I0   D3ZIS5   A8E4L1   A0A287DBD1   A0A0P6K2Z3   A0A132AIX8   A0A250XUW7   A0A182FVS7   A0A1L8EQC5   A0A340Y5Y3   A0A1S3FQV1   A0A1W0XBM6   G3SV53   A0A3B4D5X0  

KEGG

101746871    K18183 cytochrome c oxidase assembly protein subunit 19 | (RefSeq) cytochrome c oxidase assembly pro

GO

GO:0003824   GO:0005829   GO:0030001   GO:0005758   GO:0005507   GO:0033617   GO:0008137   GO:0005739   GO:0005689   GO:0000398   GO:0006878  

PANTHER

PTHR14942  

Subcellular location

Cytoplasm   Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated.   With evidence from 2 publications.
Cytosol   Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated.   With evidence from 2 publications.
Mitochondrion intermembrane space   Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated.   With evidence from 2 publications.
Mitochondrion   Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated.   With evidence from 2 publications.

Length:

85

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.40088

outside

1  -  85

 

 

Pi

211.592056

Theta

221.942175

Tajima's D

-0.1295

CLR

0

CSRT

0.332083395830209

Interpretation

Uncertain