Gene

KWMTBOMO04607

Pre Gene Modal

BGIBMGA005316

Annotation

PREDICTED:_uncharacterized_protein_LOC101746213_[Bombyx_mori]

Location

Bomo_Chr8(-):10640473-10641776      View in EpiBrowser

Full name

Deoxyhypusine hydroxylase      

Alternative Name

Deoxyhypusine dioxygenase
Deoxyhypusine monooxygenase

Location in the cell

Nuclear   Reliability : 1.978

CDS

ATGGTTCGATTGTCAATAATTCTAAATAGAATTCCTGTTATAAAATTTCGTAAAGGTGGGGCTAGTCATGTCGGTACAAGCTCTCCCGGAGCTTCAGGACCCACTGCTGCTGCTACTGCTGGAACCCCTGTGCAAAGCCAGCCTGCTGCAGCAATGAGTACTGGTGCTATACCAGACATAGACCTACCAGCACGTTACAAGAGACAACCACTCTCAGAAGAAGAGATTGCTTATATCAATGGAGGAGGAATTGTTTAG

Protein

MVRLSIILNRIPVIKFRKGGASHVGTSSPGASGPTAAATAGTPVQSQPAAAMSTGAIPDIDLPARYKRQPLSEEEIAYINGGGIV

Description

Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

Catalytic Activity

[eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O

Cofactor

Fe(2+)

Similarity

Belongs to the deoxyhypusine hydroxylase family.

Uniprot

H9J724   A0A2A4IZB0   A0A2H1VWF7   A0A3S2M416   S4P3T7   A0A1B0F963   + More
A0A1A9WHX0   A0A1B0BQN6   A0A0Q9XLT7   A0A0R1DT11   A0A1W4UZI3   A0A212EYR0   A0A1Q3FGM5   A0A1Q3FGG8   A0A1Q3FFW9   A0A0Q9W3D2   B4QHH1   A0A0J9U3F3   A0A0Q5VM39   Q2VKK0   Q2VKJ4   G2J5Z0   A0A1W4VC73   A0A1L8EEX2   U5ESB8   A0A158NDK1   A0A0L0C819   Q2VKI7   A0A1I8NCZ5   A0A0J9RE52   B7YZH7   A0A0R1DSN2   A0A2A3EH50   B0W2R3   T1E3F6   G2J5Y4   A0A023EE72   A0A0P8Y9Z4   A0A088A2L5   A0A1B0D8T7   A0A1B0CB85   A0A1L8EHI1   B4JW97   A0A1S4EWV3   A0A0Q5VN31   Q17N73   A0A0Q9WS23   T1E7Q3   W5JVG9   A0A2M4AKG8   A0A1Q3FHW0   A0A1J1IGM7   A0A1Q3FH20   A0A139WG59   A0A195BP30   A0A2M3ZKP3   A0A1I8NCZ0   A0A2M4AL05   A0A2M4ANR7   A0A2M4C5A7   A0A182R4P2   A0A182Y9D2   A0A2M3ZE99   A0A023ED80   K7IS90   A0A182QCI9   A0A1I8PP15   A0A0K8TRL0   A0A182N3Y9   A0A151XEE3   A0A164LPY0   A0A195CMY3   A0A195D9Y0   A0A182WDW2   A0A3L8E0A3   A0A226EY09   A0A1L8DSB1   A0A182JLK1   A0A1L8DR58   A0A0Q9X2Q8   A0A154PGU7   E2AQQ3   A0A0N0BG38   A0A0L7RB26   A0A084WIS0   B5E017   B4GAM3   F4W531   A0A182FUQ1   A0A026W6S7   A0A182HHG6   A0A182P4Y8   A0A1L8E849   A0A210QI14   A0A1D2MYH0  

EC Number

1.14.99.29

Pubmed

19121390    23622113    17994087    17550304    22118469    22936249    + More
16085702    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    21347285    26108605    25315136    24330624    24945155    26483478    17510324    20920257    23761445    18362917    19820115    25244985    20075255    26369729    30249741    20798317    24438588    15632085    21719571    24508170    28812685    27289101   

EMBL

BABH01013949    NWSH01004892    PCG64604.1    ODYU01004863    SOQ45177.1    RSAL01000041    + More
RVE50857.1    GAIX01006299    JAA86261.1    CCAG010022078    JXJN01018704    CH933808    KRG04739.1    CM000158    KRK00229.1    AGBW02011442    OWR46638.1    GFDL01008339    JAV26706.1    GFDL01008399    JAV26646.1    GFDL01008597    JAV26448.1    CH940648    KRF79378.1    CM000362    EDX07316.1    CM002911    KMY94200.1    CH954179    KQS62467.1    DQ079170    DQ079171    DQ079172    DQ079173    DQ079174    DQ079175    DQ079176    AAZ42654.1    AAZ42655.1    AAZ42656.1    AAZ42657.1    AAZ42658.1    AAZ42659.1    AAZ42660.1    DQ079177    DQ079178    DQ079179    DQ079180    DQ079181    DQ079182    DQ079183    AAZ42661.1    AAZ42662.1    AAZ42663.1    AAZ42664.1    AAZ42665.1    AAZ42666.1    AAZ42667.1    KRG04740.1    AE013599    BT128847    KX531797    ADV37203.1    AEM98445.1    ANY27607.1    GFDG01001558    JAV17241.1    GANO01003314    JAB56557.1    ADTU01012643    JRES01000883    KNC27564.1    DQ079184    AAZ42668.1    KMY94201.1    BT125795    ACL83130.1    ADR66769.1    KRK00230.1    KZ288252    PBC31038.1    DS231828    EDS29816.1    GALA01000400    JAA94452.1    BT128841    AEM92672.1    JXUM01147457    GAPW01006669    KQ570372    JAC06929.1    KXJ68376.1    CH902619    KPU75937.1    AJVK01027725    AJWK01004883    GFDG01000723    JAV18076.1    CH916375    EDV98235.1    KQS62468.1    CH477201    EAT48181.1    CH964154    KRF99087.1    GAMD01003453    JAA98137.1    ADMH02000368    ETN66809.1    GGFK01007965    MBW41286.1    GFDL01007889    JAV27156.1    CVRI01000047    CRK98198.1    GFDL01008242    JAV26803.1    KQ971351    KYB26787.1    KQ976424    KYM88270.1    GGFM01008386    MBW29137.1    GGFK01008155    MBW41476.1    GGFK01009115    MBW42436.1    GGFJ01011190    MBW60331.1    GGFM01006057    MBW26808.1    GAPW01006792    JAC06806.1    AXCN02001095    GDAI01000599    JAI17004.1    KQ982254    KYQ58742.1    LRGB01003123    KZS04327.1    KQ977600    KYN01449.1    KQ981082    KYN09667.1    QOIP01000002    RLU25913.1    LNIX01000001    OXA61721.1    GFDF01004755    JAV09329.1    GFDF01005132    JAV08952.1    KRF99088.1    KQ434899    KZC11027.1    GL441804    EFN64242.1    KQ435793    KOX74242.1    KQ414617    KOC68122.1    ATLV01023945    KE525347    KFB50114.1    CM000071    EDY68901.1    CH479181    EDW31975.1    GL887596    EGI70727.1    KK107399    EZA51331.1    APCN01002408    GFDG01003882    JAV14917.1    NEDP02003547    OWF48428.1    LJIJ01000418    ODM97705.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000092444    UP000091820    UP000092460    + More
UP000009192    UP000002282    UP000192221    UP000007151    UP000008792    UP000000304    UP000008711    UP000000803    UP000005205    UP000037069    UP000095301    UP000242457    UP000002320    UP000069940    UP000249989    UP000007801    UP000005203    UP000092462    UP000092461    UP000001070    UP000008820    UP000007798    UP000000673    UP000183832    UP000007266    UP000078540    UP000075900    UP000076408    UP000002358    UP000075886    UP000095300    UP000075884    UP000075809    UP000076858    UP000078542    UP000078492    UP000075920    UP000279307    UP000198287    UP000075880    UP000076502    UP000000311    UP000053105    UP000053825    UP000030765    UP000001819    UP000008744    UP000007755    UP000069272    UP000053097    UP000075840    UP000075885    UP000242188    UP000094527   

PRIDE

H9J724    G2J5Z0    G2J5Y4   

Pfam

PF10937   S36_mt

Interpro

IPR020373   Ribosomal_S36_mt        + More
IPR027517   Deoxyhypusine_hydroxylase       
IPR011989   ARM-like       
IPR016024   ARM-type_fold       
IPR004155   PBS_lyase_HEAT       

SUPFAM

SSF48371   SSF48371       

Gene 3D

1.25.10.10    

ProteinModelPortal

H9J724   A0A2A4IZB0   A0A2H1VWF7   A0A3S2M416   S4P3T7   A0A1B0F963   + More
A0A1A9WHX0   A0A1B0BQN6   A0A0Q9XLT7   A0A0R1DT11   A0A1W4UZI3   A0A212EYR0   A0A1Q3FGM5   A0A1Q3FGG8   A0A1Q3FFW9   A0A0Q9W3D2   B4QHH1   A0A0J9U3F3   A0A0Q5VM39   Q2VKK0   Q2VKJ4   G2J5Z0   A0A1W4VC73   A0A1L8EEX2   U5ESB8   A0A158NDK1   A0A0L0C819   Q2VKI7   A0A1I8NCZ5   A0A0J9RE52   B7YZH7   A0A0R1DSN2   A0A2A3EH50   B0W2R3   T1E3F6   G2J5Y4   A0A023EE72   A0A0P8Y9Z4   A0A088A2L5   A0A1B0D8T7   A0A1B0CB85   A0A1L8EHI1   B4JW97   A0A1S4EWV3   A0A0Q5VN31   Q17N73   A0A0Q9WS23   T1E7Q3   W5JVG9   A0A2M4AKG8   A0A1Q3FHW0   A0A1J1IGM7   A0A1Q3FH20   A0A139WG59   A0A195BP30   A0A2M3ZKP3   A0A1I8NCZ0   A0A2M4AL05   A0A2M4ANR7   A0A2M4C5A7   A0A182R4P2   A0A182Y9D2   A0A2M3ZE99   A0A023ED80   K7IS90   A0A182QCI9   A0A1I8PP15   A0A0K8TRL0   A0A182N3Y9   A0A151XEE3   A0A164LPY0   A0A195CMY3   A0A195D9Y0   A0A182WDW2   A0A3L8E0A3   A0A226EY09   A0A1L8DSB1   A0A182JLK1   A0A1L8DR58   A0A0Q9X2Q8   A0A154PGU7   E2AQQ3   A0A0N0BG38   A0A0L7RB26   A0A084WIS0   B5E017   B4GAM3   F4W531   A0A182FUQ1   A0A026W6S7   A0A182HHG6   A0A182P4Y8   A0A1L8E849   A0A210QI14   A0A1D2MYH0  

KEGG

101746213    K17414 small subunit ribosomal protein S36 | (RefSeq) uncharacterized LOC101746213

GO

GO:0005840   GO:0019135   GO:0008612   GO:0046872  

PANTHER

PTHR31601  

Length:

85

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01841

Exp number, first 60 AAs:

0.01841

Total prob of N-in:

0.26960

outside

1  -  85

 

 

Pi

225.278952

Theta

214.379598

Tajima's D

-0.227611

CLR

0.976851

CSRT

0.312384380780961

Interpretation

Uncertain