SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO04605  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA005493
Annotation
enolase_[Bombyx_mori]
Location
Bomo_Chr8(+):10625527-10634622      View in EpiBrowser
Full name
Enolase      
Alternative Name
2-phospho-D-glycerate hydro-lyase
2-phosphoglycerate dehydratase
Location in the cell
Cytoplasmic   Reliability : 4.451
 

Sequence

CDS
ATGGTAATAAAATCAATCAAGGCTCGTCAAATCTTTGACTCTCGTGGCAACCCTACTGTGGAAGTTGATCTGGTAACAGAGCTTGGCTTGTTCCGGGCAGCTGTACCCTCTGGTGCATCCACTGGTGTTCATGAAGCTCTTGAACTAAGAGATAACATCAAGAGTGAATATCATGGCAAGGGAGTTTTGACCGCAATCAAAAATATCAATGAACTCATTGCTCCTGAACTTACAAAAGCCAACCTCGAAGTAACCCAACAGAGAGAGATTGATGAACTCATGCTTAAGTTGGATGGCACTGAGAACAAATCCAAACTGGGTGCTAATGCTATCCTTGGAGTTTCCCTAGCTGTTGCTAAGGCTGGTGCTGCCAAGAAGAATGTTCCGCTGTACAAGCACTTGGCTGATTTGGCTGGAAATAATGACATTGTTCTACCTGTACCAGCATTCAATGTGATCAATGGAGGATCACATGCTGGAAATAAACTTGCCATGCAGGAATTCATGATTTTCCCTACAGGGGCATCCACCTTCAGTGAAGCCATGAGGATGGGTTCAGAAGTGTACCACCATTTGAAAAAGATCATTAAGGAGAAGTTTGGATTGGACTCTACGGCTGTTGGTGATGAAGGTGGTTTCGCTCCAAACATACAAAACAACAAGGATGCTCTTTATCTGATTCAGGATGCTATCCAGAAAGCTGGCTATGCTGGCAAGATCGACATTGGCATGGATGTAGCCGCCTCTGAGTTCTTCAAGGATGGAAAATACGACCTTGACTTTAAGAATCCCGATTCCAATCCAGGCGACTACCTGTCATCAGATAAATTAGCTGATGTCTATTTGGACTTCATCAAAGATTTTCCCATGGTGTCCATTGAGGATCCTTTTGACCAGGATGATTGGTCTGCATGGGCTAACCTCACTGGTCGCACGCCTATTCAGATTGTTGGTGATGATCTAACGGTGACAAACCCTAAGCGTATCGCTACTGCAGTTGAGAAGAAGGCATGCAACTGTCTGCTATTGAAGGTCAATCAGATCGGCAGCGTAACAGAGTCAATTGATGCTCACTTGCTGGCCAAGAAGAACGGATGGGGCACAATGGTCTCTCACAGATCTGGTGAGACCGAAGATACCTTTATTGCCGACCTGGTAGTTGGTTTGTCCACGGGTCAGATCAAGACCGGCGCCCCGTGTCGCTCGGAGCGTCTCGCCAAGTACAACCAAATTCTGCGCATTGAAGAGGAACTTGGCGTCAACGCCAAATACGCCGGGAAGAACTTCCGTAGACCGGTCTAA
Protein
MVIKSIKARQIFDSRGNPTVEVDLVTELGLFRAAVPSGASTGVHEALELRDNIKSEYHGKGVLTAIKNINELIAPELTKANLEVTQQREIDELMLKLDGTENKSKLGANAILGVSLAVAKAGAAKKNVPLYKHLADLAGNNDIVLPVPAFNVINGGSHAGNKLAMQEFMIFPTGASTFSEAMRMGSEVYHHLKKIIKEKFGLDSTAVGDEGGFAPNIQNNKDALYLIQDAIQKAGYAGKIDIGMDVAASEFFKDGKYDLDFKNPDSNPGDYLSSDKLADVYLDFIKDFPMVSIEDPFDQDDWSAWANLTGRTPIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGSVTESIDAHLLAKKNGWGTMVSHRSGETEDTFIADLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEELGVNAKYAGKNFRRPV

Summary

Catalytic Activity
(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate
Cofactor
Mg(2+)
Subunit
Homodimer.
Similarity
Belongs to the enolase family.
Keywords
3D-structure   Alternative splicing   Complete proteome   Cytoplasm   Direct protein sequencing   Glycolysis   Lyase   Magnesium   Metal-binding   Polymorphism   Reference proteome  
Feature
chain  Enolase
splice variant  In isoform A.
Uniprot
H9J7K1   A0A1L7P084   A1YQ87   E3T796   S5G1I9   A0A0K2CU86   + More
A0A194QY73   I4DJA8   S4PLS1   F0UYI6   B3TED4   A0A0L7LLA9   A0A1D1YYT3   L7R404   L7R6W4   A0A212EYR3   A0A1Y1KVP6   A0A1W4WXQ7   A0A0T6B9W0   V5SHY9   T1E222   A0A182XZJ5   L7R3A3   A0A182QRK1   A0A1Y9H9P7   A0A240PKU2   A0A182P0G3   A0A1S4GX21   A0A1C7CZ11   A0A182UQ73   A0A182U3K2   A0A182X1L6   A0A182IEJ8   A0A1I8JVF3   A0A182MZE9   A0A1I8JV65   A0A182L2F0   A0A1Y9IM13   A0A1I8JT09   A0A182SGM0   Q7Q3D8   A0A0L0CCJ1   A0A2C9H419   A0A182MR29   A0A2C9GUE1   B3MKE9   A0A084VBB8   A0A1Y9HCG0   D6X009   A0A1Y9IVW2   A0A1Y9IVE2   A0A182RVL0   A0A240PJZ3   A0A182JPU4   Q17KK5   A0A023ETA6   B4KKU1   T1E772   A0A2M4A0M5   A0A2M4BNJ2   B0W1N4   A0A2K6V9K4   A0A182F2Z4   A0A1I8JSH0   W5JR97   A0A2M3YZD2   A0A0M4EBN0   A0A182H609   A0A336M011   B4JZ81   A0A1W4V158   A0A182IZK9   B4LVK3   A0A240PNQ1   W8GMW5   A0A1L8E1X5   B4IDB4   A0A1A9WZY7   J3JXB7   A0A0J9QTZ3   B4P3K9   A0A1Q3FK90   A0A151IXY3   A0A1L8E1V7   U5EVU9   A0A0Q5W8I0   A0A0A1WYC5   A0A195B3Y6   A0A1D2NE37   A5XD63   A0A034VN28   A0A0C9RZV9   A0A336MWX8   A0A0N8CXU9   A5XD38   A0A0P5WEU9   B3TED5   P15007   W8BG43   A0A0K8VLF5  
EC Number
4.2.1.11
Pubmed
19121390    28086791    20923858    26263512    26354079    22651552    + More
23622113    21265041    26227816    22118469    28004739    24330624    25244985    12364791    20966253    14747013    17210077    26108605    17994087    24438588    18362917    19820115    17510324    24945155    20920257    23761445    26483478    22516182    23537049    22936249    17550304    25830018    27289101    17379620    25348373    2106662    10731132    12537572    12537569    8500545    24495485   
EMBL
BABH01013947    BABH01013948    BABH01013949    LC170036    BAW35594.1    EF121427    + More
ABL73887.1    GU289926    ADO40102.1    KC832292    AGQ53952.1    KT218671    ALA09391.1    KQ461154    KPJ08526.1    AK401376    KQ459595    BAM17998.1    KPI95597.1    GAIX01003885    JAA88675.1    FJ882068    ACZ68117.1    EU032900    ABW39167.1    JTDY01000648    KOB76343.1    GDJX01008128    JAT59808.1    JQ789814    AGB91624.1    JQ789671    AGB91481.1    AGBW02011442    OWR46639.1    GEZM01072559    GEZM01072558    JAV65469.1    LJIG01009043    KRT83869.1    KF647623    AHB50485.1    GALA01001134    JAA93718.1    JQ789534    AGB91344.1    AXCN02000606    AAAB01008964    APCN01005204    EAA12254.2    JRES01000569    KNC30153.1    AXCM01006351    CH902620    EDV32533.1    ATLV01006318    KE524352    KFB35262.1    KQ971372    EFA10506.1    CH477223    EAT47221.1    GAPW01001537    JAC12061.1    CH933807    EDW11671.2    GAMD01003302    JAA98288.1    GGFK01000988    MBW34309.1    GGFJ01005506    MBW54647.1    DS231823    EDS26585.1    ADMH02000571    ETN65833.1    GGFM01000879    MBW21630.1    CP012523    ALC40026.1    JXUM01113158    KQ565663    KXJ70801.1    UFQT01000246    SSX22339.1    CH916379    EDV94190.1    CH940649    EDW64397.1    KF986614    AHK26792.1    GFDF01001363    JAV12721.1    CH480829    EDW45540.1    APGK01052696    APGK01052697    BT127886    KB741213    KB631874    AEE62848.1    ENN72673.1    ERL86865.1    CM002910    KMY87511.1    CM000157    EDW87276.1    GFDL01007142    JAV27903.1    KQ980796    KYN12966.1    GFDF01001364    JAV12720.1    GANO01003248    JAB56623.1    CH954177    KQS69959.1    GBXI01010213    JAD04079.1    KQ976618    KYM79196.1    LJIJ01000076    ODN03365.1    DQ864214    DQ864215    DQ864216    DQ864217    DQ864218    DQ864219    DQ864220    DQ864221    DQ864222    DQ864223    DQ864224    DQ864225    DQ864226    ABH06849.1    ABH06850.1    ABH06851.1    ABH06852.1    ABH06853.1    ABH06854.1    ABH06855.1    ABH06856.1    ABH06857.1    ABH06858.1    ABH06859.1    ABH06860.1    ABH06861.1    GAKP01015979    JAC42973.1    GBYB01013676    JAG83443.1    UFQT01003345    SSX34892.1    GDIP01088255    JAM15460.1    DQ864189    ABH06824.1    GDIP01087201    JAM16514.1    EU032901    ABW39168.1    X17034    AE014134    AY118449    BT014924    BT058002    BT072929    DQ864190    DQ864191    DQ864192    DQ864193    DQ864194    DQ864195    DQ864196    DQ864197    DQ864198    DQ864199    DQ864200    DQ864201    DQ864202    DQ864203    DQ864204    DQ864205    DQ864206    DQ864207    DQ864208    DQ864209    DQ864210    DQ864211    DQ864212    DQ864213    GAMC01010637    JAB95918.1    GDHF01012929    JAI39385.1   
Proteomes
UP000005204    UP000053240    UP000053268    UP000037510    UP000007151    UP000192223    + More
UP000076408    UP000075886    UP000075885    UP000075882    UP000075903    UP000075902    UP000076407    UP000075840    UP000075884    UP000075901    UP000007062    UP000037069    UP000075883    UP000007801    UP000030765    UP000075900    UP000007266    UP000075920    UP000075881    UP000008820    UP000009192    UP000002320    UP000069272    UP000000673    UP000092553    UP000069940    UP000249989    UP000001070    UP000192221    UP000075880    UP000008792    UP000001292    UP000091820    UP000019118    UP000030742    UP000002282    UP000078492    UP000008711    UP000078540    UP000094527    UP000000803   
PRIDE
H9J7K1    A1YQ87    B3TED4    P15007   
Pfam
PF03952   Enolase_N        + More
PF00113   Enolase_C
Interpro
IPR020809   Enolase_CS        + More
IPR029017   Enolase-like_N       
IPR000941   Enolase       
IPR036849   Enolase-like_C_sf       
IPR020810   Enolase_C       
IPR020811   Enolase_N       
SUPFAM
SSF51604   SSF51604       
Gene 3D
3.20.20.120     3.30.390.10    
CDD
cd03313  enolase
ProteinModelPortal
H9J7K1   A0A1L7P084   A1YQ87   E3T796   S5G1I9   A0A0K2CU86   + More
A0A194QY73   I4DJA8   S4PLS1   F0UYI6   B3TED4   A0A0L7LLA9   A0A1D1YYT3   L7R404   L7R6W4   A0A212EYR3   A0A1Y1KVP6   A0A1W4WXQ7   A0A0T6B9W0   V5SHY9   T1E222   A0A182XZJ5   L7R3A3   A0A182QRK1   A0A1Y9H9P7   A0A240PKU2   A0A182P0G3   A0A1S4GX21   A0A1C7CZ11   A0A182UQ73   A0A182U3K2   A0A182X1L6   A0A182IEJ8   A0A1I8JVF3   A0A182MZE9   A0A1I8JV65   A0A182L2F0   A0A1Y9IM13   A0A1I8JT09   A0A182SGM0   Q7Q3D8   A0A0L0CCJ1   A0A2C9H419   A0A182MR29   A0A2C9GUE1   B3MKE9   A0A084VBB8   A0A1Y9HCG0   D6X009   A0A1Y9IVW2   A0A1Y9IVE2   A0A182RVL0   A0A240PJZ3   A0A182JPU4   Q17KK5   A0A023ETA6   B4KKU1   T1E772   A0A2M4A0M5   A0A2M4BNJ2   B0W1N4   A0A2K6V9K4   A0A182F2Z4   A0A1I8JSH0   W5JR97   A0A2M3YZD2   A0A0M4EBN0   A0A182H609   A0A336M011   B4JZ81   A0A1W4V158   A0A182IZK9   B4LVK3   A0A240PNQ1   W8GMW5   A0A1L8E1X5   B4IDB4   A0A1A9WZY7   J3JXB7   A0A0J9QTZ3   B4P3K9   A0A1Q3FK90   A0A151IXY3   A0A1L8E1V7   U5EVU9   A0A0Q5W8I0   A0A0A1WYC5   A0A195B3Y6   A0A1D2NE37   A5XD63   A0A034VN28   A0A0C9RZV9   A0A336MWX8   A0A0N8CXU9   A5XD38   A0A0P5WEU9   B3TED5   P15007   W8BG43   A0A0K8VLF5  
PDB
5WRO     E-value=0,     Score=1786

Ontologies

KEGG
100037426    K01689 enolase [EC:4.2.1.11] | (RefSeq) enolase
PATHWAY
00010    Glycolysis / Gluconeogenesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)
03018    RNA degradation - Bombyx mori (domestic silkworm)
GO
GO:0000015   GO:0006096   GO:0000287   GO:0004634   GO:0042593   GO:0005737   GO:0005886   GO:0016491   GO:0007165   GO:0015031   GO:0016020   GO:0016742   GO:0003824  
PANTHER
PTHR11902  

Topology

Subcellular location
Cytoplasm  
Length:
433
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.18845
Exp number, first 60 AAs:
0.00144
Total prob of N-in:
0.03780
outside
1  -  433
 
 

Population Genetic Test Statistics

Pi
286.729874
Theta
161.041784
Tajima's D
2.683491
CLR
0.428906
CSRT
0.960601969901505
Interpretation
Possibly Positive selection
Peptides ×
Source Sequence Identity Evalue
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 3e-14
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 3e-14
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 3e-14
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 3e-14
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 3e-14
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 3e-14
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 3e-14
28556443 HLADLAGNNDIVLPVPAF 100.00 3e-14
28556443 FGLDSTAVGDEGGFAPNIQNNK 100.00 3e-14
26822097 MGSEVYHHIK 95.83 6e-10
28467696 EKFEDITIKPTR 95.83 6e-10
28556443 FGLDSTAVGDEGGFAPNIQNNK 100.00 7e-09
28556443 FGLDSTAVGDEGGFAPN 100.00 7e-09
28556443 FGLDSTAVGDEGGFAPN 100.00 7e-09
28556443 LAMQEFMIFPTGASTFSEAMR 100.00 7e-09
28556443 LAMQEFMIFPTGASTFSEAMR 100.00 7e-09
28556443 LADVYLDFIK 100.00 7e-09
28556443 LADVYLDFIK 100.00 7e-09
26822097 EIDEIMIK 95.45 1e-08
26280517 FFIESR 95.45 1e-08
25044914 FGHVFMSETGTSVGEISGQSK 95.45 1e-08
27102218 DNIKSEYHGK 95.45 1e-08
28467696 FGHSIIPTAVER 95.45 1e-08
26280517 IAEQIDFVNHNVR 95.24 2e-08
25044914 IAMETFGVTEGNIGK 95.24 2e-08
28467696 IAMMTIDAGR 95.24 2e-08
31250652 NSFGVYPVGGLAVGAVGAGAGAEAALPLATHGPVQR 100.00 6e-07
28556443 GVLTAIK 100.00 3e-06
28556443 EIDELMLK 100.00 3e-06
28556443 AAVPSGASTGVHEALELR 100.00 2e-05
28556443 GASTFSEAMR 100.00 2e-05
28556443 TGNLLVTTGVVDPK 100.00 2e-05
28556443 TPIQIVGDDLTVTNPK 100.00 2e-05
28556443 VNQIGSVTESIDAHLLAK 100.00 3e-05
28556443 VNQIGSVTESIDAHLLAK 100.00 3e-05
28556443 VNQIGSVTESIDAHLLAK 100.00 3e-05
28556443 VNQIGSVTESIDAHLLAK 100.00 3e-05
28556443 TPIQIVGDDLTVTNPK 100.00 3e-05
28556443 TPIQIVGDDLTVTNPKR 100.00 3e-05
28556443 EIDELMLK 100.00 3e-05
28556443 DALYLIQDAIQK 100.00 3e-05
28556443 MIFPTGASTFSEAMR 100.00 2e-04
28556443 MIFPTGASTFSEAMR 100.00 2e-04
28556443 MIFPTGASTFSEAMR 100.00 2e-04
28556443 MIFPTGASTFSEAMR 100.00 2e-04
28556443 MGSEVYHHLK 100.00 2e-04
28556443 MGSEVYHHLK 100.00 2e-04
28556443 TPIQIVGDDLTVTNPK 100.00 2e-04
28556443 TPIQIVGDDLTVTNPK 100.00 2e-04
28556443 TPIQIVGDDLTVTNPK 100.00 2e-04
28556443 TPIQIVGDDLTVTNPK 100.00 2e-04
28556443 NPDSNPGDYLSSDK 100.00 2e-04
28556443 NPDSNPGDYLSSDK 100.00 2e-04
28556443 QIFDSR 100.00 0.001
28556443 NPDSNPGDYLSSDK 100.00 0.003
28556443 NINELIAPELTK 100.00 0.003
28556443 NINELIAPELTK 100.00 0.003
26280517 ICEEIAIIPTKPIR 100.00 0.008
25044914 IDIEAWFPGSGAFR 100.00 0.008
28467696 IDIGEAIENNIEK 100.00 0.008
28556443 IDIGMDVAASEFFK 100.00 0.008
28556443 IDIGMDVAASEFFK 100.00 0.008
28556443 IDIGMDVAASEFFK 100.00 0.008
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 0.008
28556443 HLADLAGNNDIVLPVPAFNVINGGSHAGNK 100.00 0.008
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