Gene

KWMTBOMO04597  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005320

Annotation

PREDICTED:_carboxypeptidase_D-like_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr8(-):10515469-10531049      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.436 Extracellular   Reliability : 1.14

CDS

ATGCTGGCTGGTTCGACATTTGCGCAATCTTTTCATAATCCAAGCTTAAATGGAGAAGAAACGTCAACCAATCTAGGTGAAGTGGAATCACGTGAAAATGCTCCAGACTTGGAGTTTCAATATCACGATCATGATCAGATGACGCGGTATCTACGTGCAGTTTCTGCCAAATATCCTGAACTCACAGCTTTATATTCCATTGGGAAGTCGGTACAAGGTCGAGATCTATGGGTGATGGTCGTCTCTGTGTCTCCATACGAGCACATGATTGGGAAGCCTGATGTTAAATATGTGGCTAACATACACGGTAACGAAGCAGTAGGACGGGAGCTACTTCTACATCTTATACAGTATTTAGTGACGTCGTATGCAACTGATCCGTACGTGAAATGGCTGTTGGACAACACACGTATTCACTTAATGCCCTCAATGAATCCTGATGGTTTCGCAATATCGAGGGAAGGACAATGCGACACCATACATGGCAGGCACAATGCACGTCGTCATGATTTGAACAGGAATTTTCCCGATTTTTTCAAAGCGAATACAAAACAGCCTCAGCCAGAAACGGAAGCAGTGAAACAATGGATCAGCAAAATACAGTTCGTTCTCTCTGGGTCGCTGCATGGCGGTGCTCTGGTCGCGTCTTATCCTTTCGACAACACTCCCAGTTCTACAGTGTTTCAAAACTATGAACACACGCCGTCAATATCTCCCGATGATGATGTCTTCAAACATTTGTCCTTGGTATACTCTAAAAACCATGCCAAAATGTCTCGAGGTGTCTCTTGCAAATCGGGATCACCAAGATTCGAAAATGGCATTACAAATGGAGCGGCCTGGTATCCACTGACAGGTGGCATGCAAGACTACAACTACCTGTGGCACGGATGTATGGAAGTCACTTTAGAAATATCTTGCTGTAAATATCCCCCAGCCCACGAATTACCCAAATACTGGCAAGACAATAAACAGTCTCTTATAAAATACTTAGCGGAAGTACACCGAGGTGCCCACGGCTTTGTCATGGATGAAAATAATAATCCAGTAGAGCGTGCAGCTATCAAAATCAAAGGACGAGATGTCAATTATCATACTACTAACTTCGGAGAATTTTGGCGCATTCTTTTACCCGGAACGTACCGCATGGACATTTCGGCGGAGGGATATTTACCACAAGAAGTAGAATTTATTGTTATTGATAGCCATCCAACGCTATTAAATGTTACTTTGCGTTCCGCGAAGGATGTTACAACCCGTCCAACAACAAGCGAATCTGAAGAAGCGATGACCACCTCAATCATTACAACCACAATGGACCCTGAAGAAACTATTGTTTTTCCTGAAGACTAG

Protein

MLAGSTFAQSFHNPSLNGEETSTNLGEVESRENAPDLEFQYHDHDQMTRYLRAVSAKYPELTALYSIGKSVQGRDLWVMVVSVSPYEHMIGKPDVKYVANIHGNEAVGRELLLHLIQYLVTSYATDPYVKWLLDNTRIHLMPSMNPDGFAISREGQCDTIHGRHNARRHDLNRNFPDFFKANTKQPQPETEAVKQWISKIQFVLSGSLHGGALVASYPFDNTPSSTVFQNYEHTPSISPDDDVFKHLSLVYSKNHAKMSRGVSCKSGSPRFENGITNGAAWYPLTGGMQDYNYLWHGCMEVTLEISCCKYPPAHELPKYWQDNKQSLIKYLAEVHRGAHGFVMDENNNPVERAAIKIKGRDVNYHTTNFGEFWRILLPGTYRMDISAEGYLPQEVEFIVIDSHPTLLNVTLRSAKDVTTRPTTSESEEAMTTSIITTTMDPEETIVFPED

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Uniprot

A0A2H1V3E3   A0A194PQK2   A0A212F5K1   A0A194QY63   W8B0P1   A0A1B0CR20   + More
A0A0K8VPW2   A0A0K8V2T1   A0A0A1XR52   A0A0K8VCR1   A0A034VHI3   A0A0A1WWD8   A0A1B0DJT4   A0A1I8M573   B4M280   A0A182G4V6   B4L1N7   A0A1I8M569   A0A1I8Q574   A0A182GM98   A0A1I8M574   A0A1I8M576   A0A1I8Q580   A0A0Q9WLL3   B4JIV8   A0A0Q9WQ54   A0A0Q9X062   A0A1B1UZG6   B0XKN5   A0A0P6IY98   A0A0Q9WY01   A0A1Q3FNI8   Q9VXC4   A0A0M3QZ87   A0A1I8Q572   B7Z0Z6   A0A1W4VX05   Q16RA6   A0A2H8U1T6   A0A0P8XL69   A0A0L0C9K7   Q29IJ7   A0A023GPN7   B3NVL6   M9NFA0   G4LU56   A0A2S2PCI8   A0A1I8Q562   B4NDT0   A0A1Q3FNE4   A0A1I8Q5A8   B4Q1U0   A0A1S4G7R5   A0A1B0BR12   A0A1W4VIZ4   A0A0P8XL55   A0A182V964   X2JFS7   A0A2J7PJV6   A0A2M4CQM3   B3MWA7   A0A0Q5THM9   A0A182U1Y6   A0A182I9I5   A0A182XEL6   A0A182LRG1   A0A1A9Y2X6   A0A0R1EBE5   A0A1W4VIR3   A0A3B0K5D3   A0A0P9AB63   A0A1B0A9X9   A0A067R6S5   A0A0Q5T3K9   A0A1V1FTI7   W5JLU2   A0A1W4VW68   A0A182Q3Q2   A4V4N7   A0A182XXR0   A0A1B6GXV1   A0A0Q5T3V4   A0A182FIJ0   A0A182RPG6   A0A182NAB7   B7Z0Z5   J9JWQ5   A0A0R1EIA7   A0A2J7PJX9   A0A1B6E9U3   A0A182LIM4   F5HJX9   Q7PRP0   A0A1A9VC85   A0A182W480   A0A224XFS6   A0A2K8JS22   A0A0R1EBL9   A0A182KB53   A0A1B6M867  

Pubmed

26354079    22118469    24495485    25830018    25348373    25315136    + More
17994087    26483478    26999592    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17510324    26108605    15632085    17550304    24845553    28410430    20920257    23761445    25244985    20966253    12364791    14747013    17210077   

EMBL

ODYU01000493    SOQ35365.1    KQ459595    KPI95587.1    AGBW02010183    OWR49003.1    + More
KQ461154    KPJ08516.1    GAMC01011895    JAB94660.1    AJWK01024342    AJWK01024343    GDHF01011431    GDHF01003535    JAI40883.1    JAI48779.1    GDHF01019191    JAI33123.1    GBXI01000523    JAD13769.1    GDHF01015677    JAI36637.1    GAKP01017752    JAC41200.1    GBXI01010933    JAD03359.1    AJVK01001052    AJVK01001053    AJVK01001054    CH940651    EDW65784.2    JXUM01144536    KQ569811    KXJ68512.1    CH933810    EDW07673.2    JXUM01074065    KQ562810    KXJ75079.1    KRF82417.1    CH916370    EDV99522.1    KRF82416.1    KRF94133.1    KX428487    ANW09598.1    DS233924    EDS32354.1    GDUN01000121    JAN95798.1    KRF94132.1    GFDL01005876    JAV29169.1    AE014298    AAF48652.3    CP012528    ALC48949.1    BT132702    ACL82940.1    AEQ72804.2    CH477719    EAT36941.1    GFXV01008047    MBW19852.1    CH902625    KPU75497.1    JRES01000728    KNC28936.1    CH379063    EAL32656.2    ABC67188.2    CH954180    EDV46408.1    AFH07431.1    BT132686    AEQ62990.1    GGMR01014554    MBY27173.1    CH964239    EDW81899.2    GFDL01006042    JAV29003.1    CM000162    EDX02515.1    JXJN01018875    KPU75496.1    AHN59814.1    NEVH01024944    PNF16608.1    GGFL01003401    MBW67579.1    EDV35252.2    KQS29963.1    APCN01000984    AXCM01000900    KRK06812.1    OUUW01000021    SPP89424.1    KPU75495.1    KK852704    KDR18068.1    KQS29964.1    FX985402    BAX07415.1    ADMH02001203    ETN63744.1    AXCN02002441    AAN09418.2    GECZ01002511    JAS67258.1    KQS29965.1    ACL82941.1    ABLF02026859    ABLF02026864    KRK06810.1    PNF16609.1    GEDC01002664    JAS34634.1    AAAB01008847    EGK96595.1    EAA06873.5    GFTR01006542    JAW09884.1    KY031089    ATU82840.1    KRK06811.1    GEBQ01007854    JAT32123.1   

Proteomes

UP000053268    UP000007151    UP000053240    UP000092461    UP000092462    UP000095301    + More
UP000008792    UP000069940    UP000249989    UP000009192    UP000095300    UP000001070    UP000002320    UP000000803    UP000092553    UP000192221    UP000008820    UP000007801    UP000037069    UP000001819    UP000008711    UP000007798    UP000002282    UP000092460    UP000075903    UP000235965    UP000075902    UP000075840    UP000076407    UP000075883    UP000092443    UP000268350    UP000092445    UP000027135    UP000000673    UP000075886    UP000076408    UP000069272    UP000075900    UP000075884    UP000007819    UP000075882    UP000007062    UP000078200    UP000075920    UP000075881   

PRIDE

Q9VXC4   

Pfam

PF00246   Peptidase_M14        + More
PF00135   COesterase
PF08596   Lgl_C
PF08366   LLGL

Interpro

IPR015567   Pept_M14B_carboxypept_D2        + More
IPR000834   Peptidase_M14       
IPR008969   CarboxyPept-like_regulatory       
IPR029058   AB_hydrolase       
IPR002018   CarbesteraseB       
IPR019826   Carboxylesterase_B_AS       
IPR019819   Carboxylesterase_B_CS       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       
IPR000664   Lethal2_giant       
IPR013577   LLGL2       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR013905   Lgl_C_dom       
IPR001388   Synaptobrevin       
IPR001680   WD40_repeat       

SUPFAM

SSF49464   SSF49464        + More
SSF53474   SSF53474       
SSF50978   SSF50978       

Gene 3D

3.40.50.1820     2.130.10.10    

ProteinModelPortal

A0A2H1V3E3   A0A194PQK2   A0A212F5K1   A0A194QY63   W8B0P1   A0A1B0CR20   + More
A0A0K8VPW2   A0A0K8V2T1   A0A0A1XR52   A0A0K8VCR1   A0A034VHI3   A0A0A1WWD8   A0A1B0DJT4   A0A1I8M573   B4M280   A0A182G4V6   B4L1N7   A0A1I8M569   A0A1I8Q574   A0A182GM98   A0A1I8M574   A0A1I8M576   A0A1I8Q580   A0A0Q9WLL3   B4JIV8   A0A0Q9WQ54   A0A0Q9X062   A0A1B1UZG6   B0XKN5   A0A0P6IY98   A0A0Q9WY01   A0A1Q3FNI8   Q9VXC4   A0A0M3QZ87   A0A1I8Q572   B7Z0Z6   A0A1W4VX05   Q16RA6   A0A2H8U1T6   A0A0P8XL69   A0A0L0C9K7   Q29IJ7   A0A023GPN7   B3NVL6   M9NFA0   G4LU56   A0A2S2PCI8   A0A1I8Q562   B4NDT0   A0A1Q3FNE4   A0A1I8Q5A8   B4Q1U0   A0A1S4G7R5   A0A1B0BR12   A0A1W4VIZ4   A0A0P8XL55   A0A182V964   X2JFS7   A0A2J7PJV6   A0A2M4CQM3   B3MWA7   A0A0Q5THM9   A0A182U1Y6   A0A182I9I5   A0A182XEL6   A0A182LRG1   A0A1A9Y2X6   A0A0R1EBE5   A0A1W4VIR3   A0A3B0K5D3   A0A0P9AB63   A0A1B0A9X9   A0A067R6S5   A0A0Q5T3K9   A0A1V1FTI7   W5JLU2   A0A1W4VW68   A0A182Q3Q2   A4V4N7   A0A182XXR0   A0A1B6GXV1   A0A0Q5T3V4   A0A182FIJ0   A0A182RPG6   A0A182NAB7   B7Z0Z5   J9JWQ5   A0A0R1EIA7   A0A2J7PJX9   A0A1B6E9U3   A0A182LIM4   F5HJX9   Q7PRP0   A0A1A9VC85   A0A182W480   A0A224XFS6   A0A2K8JS22   A0A0R1EBL9   A0A182KB53   A0A1B6M867  

PDB

1UWY     E-value=2.0211e-104,     Score=969

KEGG

101744869    no KO assigned | (RefSeq) carboxypeptidase D-like

GO

GO:0008270   GO:0004181   GO:0016021   GO:0016192   GO:0005615   GO:0016485   GO:0006518   GO:0006508   GO:0020037   GO:0016491   GO:0007165   GO:0015031   GO:0016020   GO:0016742   GO:0003824  

PANTHER

PTHR11532:SF73  

Length:

450

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00713999999999998

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.00189

outside

1  -  450

 

 

Pi

191.129614

Theta

166.654056

Tajima's D

0.876306

CLR

0.322394

CSRT

0.629668516574171

Interpretation

Uncertain