Gene

KWMTBOMO04588

Pre Gene Modal

BGIBMGA005327

Annotation

PREDICTED:_exportin-6_[Bombyx_mori]

Location

Bomo_Chr8(-):10419146-10425899      View in EpiBrowser

Full name

Exportin-6      

Alternative Name

Ran-binding protein 20

Location in the cell

PlasmaMembrane   Reliability : 1.07

CDS

ATGGATAGGTTTTGTTGTAGCGTATTAATTCATCGGTGGCGATACTTCTTCCCGCACAAGTGCGACACGGCGGAGGGGGGGCGGCGCGCGGACGAGTTCCGCGGCGCGCTGTCTGCGCTCGGGCGCGCCCTGCTGCTGCCCGACATAGAGCTGCTCAAGCTCAACATTGCGACGCTCGAGACGCTCAACAGCAAGTGGAAACTCTATCATAAAGCTATATTCCGTTCGGAGTTCCTGTGCGAGTTCCTGTCGGTGGCGCTGGGCGGGCTGGCGGAGGGCGGCTGGCGCGGGCTGGCGCGCGACGAGCTGACGGCGGCGGTGCACGCGATGGCGGCGGTCGACTTCTCCGCGTTCCGCCTCGCCTTCCTGCCGCGCTTCCTGCGCTCGCTGCCCGGCCTCGCGCCGCACCACCTGCAGTACCTCGAGAACTTCCCACCAGATACTGATCTCCCTACGTTTACACAGAATATACATCGGCTAATCAACGACGTGAACTGTTACCGCGCCTACAACGCGGCCGCCCCGGTCGACATGGCCACCTGA

Protein

MDRFCCSVLIHRWRYFFPHKCDTAEGGRRADEFRGALSALGRALLLPDIELLKLNIATLETLNSKWKLYHKAIFRSEFLCEFLSVALGGLAEGGWRGLARDELTAAVHAMAAVDFSAFRLAFLPRFLRSLPGLAPHHLQYLENFPPDTDLPTFTQNIHRLINDVNCYRAYNAAAPVDMAT

Description

Mediates the nuclear export of actin and profilin-actin complexes in somatic cells.

Subunit

Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with ACTB. Interacts with ACTB in a RanGTP-dependent manner.

Similarity

Belongs to the exportin family.

Keywords

Acetylation   Alternative splicing   Complete proteome   Cytoplasm   Nucleus   Phosphoprotein   Protein transport   Reference proteome   Transport  

Feature

chain  Exportin-6
splice variant  In isoform 3.

Uniprot

H9J735   A0A2A4IY48   A0A2A4IS69   A0A3S2TGI4   A0A2H1V1J9   A0A194PS50   + More
A0A2J7Q0D7   A0A067R0K4   A0A147BCU1   A0A0P4W6N5   A0A131XZF0   A0A194QT65   A0A0T6B3L7   G3WLI9   G3WLI8   G3IEC6   A0A0P5T8U3   A0A0P5UFZ9   A0A0P5ZDK2   A0A0P5T6U8   A0A0P6BRQ3   A0A0P4WI96   A0A0P5TR95   A0A0P5C4I9   A0A0P4WP72   A0A0P6CQF2   A0A0P5K2A8   G3HPB0   Q924Z6-3   F6VYP1   G2HGA8   A0A093BX72   A0A2R9AZ37   A0A093BU64   V3YVJ7   F6VAC3   A0A2J8JMI0   A0A151N6D3   A0A1U7SD17   A0A2I0LP45   A0A1U8DIJ3   A0A061I3Y2   A0A3Q7WEG8   A0A3Q7XWI6   A0A2J8JMG3   H9GNQ4   A0A3Q7X2G4   A0A384BLF2   A0A2R9AZ27   H2QAT9   A0A1S3A1T8   A0A3L7I1R9   A0A1S3ESV0   A0A3B1IZW0   A0A0D9R249   F1PV74   Q8CHG0   F6Y1V2   L9KU05   A0A091I3H1   A0A091TQU3   A0A093JBL7   G1NBB3   A0A093EMF6   A0A091US61   A0A1D5PKA8   R0LD91   A0A091PIY8   G7Q0T1   A0A2K5K455   A0A091Q934   A0A091RQK7   A0A226P3S8   A0A226MYI1   G7NQG0   A0A2K6BA70   A0A2K5VRV6   A0A2K5Y6A4   A0A096NHJ9   A0A2K6RRQ0   A0A2K5M6N0   H9FRV4   A0A2K6KV43   A0A212CZK1   A0A1V4KT73   L5MAS0   S7PHR5   A0A1V4KUS4   A0A1V4KTA2   A0A093PED5   A0A091NHN9   A0A091XU57   A0A093HGA8   A0A099ZQG9   A0A091F383   A0A0A0A9S4   A0A3M0KXG6   A0A3Q7MRU4   A0A2U3XRG4   A0A091MV81  

Pubmed

19121390    26354079    24845553    29652888    21709235    21804562    + More
16141072    15489334    21183079    22323606    17495919    21484476    22722832    23254933    18464734    22293439    23371554    23929341    21881562    16136131    29704459    25329095    16341006    19892987    23385571    20838655    15592404    22002653    24621616    25362486    17431167    25319552   

EMBL

BABH01013925    BABH01013926    BABH01013927    BABH01013928    BABH01013929    BABH01013930    + More
BABH01013931    NWSH01005707    PCG64023.1    NWSH01008557    PCG62499.1    RSAL01000163    RVE45377.1    ODYU01000229    SOQ34646.1    KQ459595    KPI95579.1    NEVH01019969    PNF22047.1    KK852824    KDR15433.1    GEGO01006811    JAR88593.1    GDRN01087946    JAI60958.1    GEFM01004211    JAP71585.1    KQ461154    KPJ08509.1    LJIG01016079    KRT81677.1    AEFK01080670    AEFK01080671    AEFK01080672    AEFK01080673    AEFK01080674    AEFK01080675    AEFK01080676    AEFK01080677    AEFK01080678    AEFK01080679    JH002176    EGW12306.1    GDIP01135772    JAL67942.1    GDIP01115618    JAL88096.1    GDIP01045296    JAM58419.1    GDIP01134571    JAL69143.1    GDIP01010670    JAM93045.1    GDIP01254904    JAI68497.1    GDIP01140672    LRGB01002506    JAL63042.1    KZS07267.1    GDIP01176267    JAJ47135.1    GDIP01254858    JAI68543.1    GDIQ01089579    JAN05158.1    GDIQ01190688    GDIQ01182797    JAK61037.1    JH000570    EGW01997.1    AY029528    AK011324    AK154709    BC058090    AK305772    BAK62766.1    KL454705    KFV08315.1    AJFE02022945    AJFE02022946    AJFE02022947    AJFE02022948    AJFE02022949    KL227261    KFV03416.1    KB204066    ESO82003.1    NBAG03000444    PNI23975.1    AKHW03003917    KYO32404.1    AKCR02000159    PKK19189.1    KE680964    ERE71046.1    PNI23972.1    AAWZ02029546    AAWZ02029547    AAWZ02029548    AACZ04059639    AACZ04059640    GABC01000770    GABF01003938    GABD01005497    JAA10568.1    JAA18207.1    JAA27603.1    PNI23973.1    RAZU01000108    RLQ72134.1    AQIB01118623    AQIB01118624    AAEX03004417    AB093235    BAC41419.1    KB320653    ELW66405.1    KL218232    KFP03119.1    KK482862    KFQ61026.1    KK604636    KFW08374.1    KK372432    KFV44237.1    KL410017    KFQ93257.1    AC163700    KB743321    EOA99449.1    KK659641    KFQ07331.1    CM001295    EHH60269.1    KK689667    KFQ16061.1    KK930621    KFQ44955.1    AWGT02000179    OXB74471.1    MCFN01000356    OXB60069.1    CM001272    EHH31538.1    AQIA01042494    AQIA01042495    AQIA01042496    AQIA01042497    AHZZ02018557    JSUE03025981    JSUE03025982    JSUE03025983    JSUE03025984    JU333608    JV046545    AFE77363.1    AFI36616.1    MKHE01000010    OWK11418.1    LSYS01001700    OPJ87659.1    KB102349    ELK35417.1    KE162966    EPQ10243.1    OPJ87657.1    OPJ87658.1    KL669029    KFW75258.1    KK847050    KFP88439.1    KK735903    KFR16436.1    KL206272    KFV80751.1    KL897628    KGL84664.1    KK719436    KFO63317.1    KL871144    KGL90806.1    QRBI01000098    RMC17863.1    KK517967    KFP65400.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000235965    UP000027135    + More
UP000053240    UP000007648    UP000001075    UP000076858    UP000000589    UP000002280    UP000240080    UP000030746    UP000002279    UP000050525    UP000189705    UP000053872    UP000030759    UP000286642    UP000001646    UP000261680    UP000002277    UP000079721    UP000273346    UP000081671    UP000018467    UP000029965    UP000002254    UP000002281    UP000011518    UP000054308    UP000001645    UP000053283    UP000000539    UP000009130    UP000233080    UP000198419    UP000198323    UP000233120    UP000233100    UP000233140    UP000028761    UP000233200    UP000233060    UP000006718    UP000233180    UP000190648    UP000053258    UP000053605    UP000053584    UP000053641    UP000052976    UP000053858    UP000269221    UP000286641    UP000245341   

PRIDE

H9J735    Q924Z6   

Pfam

PF08389   Xpo1        + More
PF03810   IBN_N

Interpro

IPR040016   XPO6        + More
IPR011989   ARM-like       
IPR013598   Exportin-1/Importin-b-like       
IPR016024   ARM-type_fold       
IPR001494   Importin-beta_N       

SUPFAM

SSF48371   SSF48371       

Gene 3D

1.25.10.10    

ProteinModelPortal

H9J735   A0A2A4IY48   A0A2A4IS69   A0A3S2TGI4   A0A2H1V1J9   A0A194PS50   + More
A0A2J7Q0D7   A0A067R0K4   A0A147BCU1   A0A0P4W6N5   A0A131XZF0   A0A194QT65   A0A0T6B3L7   G3WLI9   G3WLI8   G3IEC6   A0A0P5T8U3   A0A0P5UFZ9   A0A0P5ZDK2   A0A0P5T6U8   A0A0P6BRQ3   A0A0P4WI96   A0A0P5TR95   A0A0P5C4I9   A0A0P4WP72   A0A0P6CQF2   A0A0P5K2A8   G3HPB0   Q924Z6-3   F6VYP1   G2HGA8   A0A093BX72   A0A2R9AZ37   A0A093BU64   V3YVJ7   F6VAC3   A0A2J8JMI0   A0A151N6D3   A0A1U7SD17   A0A2I0LP45   A0A1U8DIJ3   A0A061I3Y2   A0A3Q7WEG8   A0A3Q7XWI6   A0A2J8JMG3   H9GNQ4   A0A3Q7X2G4   A0A384BLF2   A0A2R9AZ27   H2QAT9   A0A1S3A1T8   A0A3L7I1R9   A0A1S3ESV0   A0A3B1IZW0   A0A0D9R249   F1PV74   Q8CHG0   F6Y1V2   L9KU05   A0A091I3H1   A0A091TQU3   A0A093JBL7   G1NBB3   A0A093EMF6   A0A091US61   A0A1D5PKA8   R0LD91   A0A091PIY8   G7Q0T1   A0A2K5K455   A0A091Q934   A0A091RQK7   A0A226P3S8   A0A226MYI1   G7NQG0   A0A2K6BA70   A0A2K5VRV6   A0A2K5Y6A4   A0A096NHJ9   A0A2K6RRQ0   A0A2K5M6N0   H9FRV4   A0A2K6KV43   A0A212CZK1   A0A1V4KT73   L5MAS0   S7PHR5   A0A1V4KUS4   A0A1V4KTA2   A0A093PED5   A0A091NHN9   A0A091XU57   A0A093HGA8   A0A099ZQG9   A0A091F383   A0A0A0A9S4   A0A3M0KXG6   A0A3Q7MRU4   A0A2U3XRG4   A0A091MV81  

KEGG

101735669    no KO assigned | (RefSeq) exportin-6

GO

GO:0008565   GO:0006611   GO:0005623   GO:0005634   GO:0008536   GO:0005730   GO:0032991   GO:0005829   GO:0005049   GO:0005886  

PANTHER

PTHR21452  

Subcellular location

Nucleus  
Cytoplasm   Shuttles between the nucleus and the cytoplasm.   With evidence from 2 publications.

Length:

180

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.57168

Exp number, first 60 AAs:

0.00254

Total prob of N-in:

0.11253

outside

1  -  180

 

 

Pi

299.916989

Theta

148.956729

Tajima's D

1.706572

CLR

0.356582

CSRT

0.831258437078146

Interpretation

Uncertain