Gene

KWMTBOMO04579

Pre Gene Modal

BGIBMGA005480

Annotation

PREDICTED:_vacuolar_fusion_protein_CCZ1_homolog_isoform_X1_[Papilio_xuthus]

Location

Bomo_Chr8(+):10347480-10353055      View in EpiBrowser

Full name

Vacuolar fusion protein CCZ1 homolog       + More
Vacuolar fusion protein CCZ1 homolog B      

Alternative Name

Vacuolar fusion protein CCZ1 homolog-like

Location in the cell

Cytoplasmic   Reliability : 1.169 PlasmaMembrane   Reliability : 1.699

CDS

ATGATAGACTTAAGATCTAAAATCAACTTTTTCTTCGTTTTTAACCCTACCTTTGGACCTAAGGAGGGCGATGAATTAAAGAGAATACTATACTTTTATCCAAATGAAGTCAGTCCAGATGCCCGGAAAATGCAAGTTGGGCTGTGTGAAGCCGTTGTCAAATTTATGTCGACGTTTTCATCTGAACCATGTGAAGCTTTGCAAACACAATCTAAGAGATACATATTTTTTCAACCAGAAAAAAACTTTTGGATGGTTTTAGTAGTCCGAATACCGTATACAACCAAAGCATTGTCAGCAGTTGGTGAAAGTCAGGGAGATATAGTCAATCCTACTGTAATGCAAAATCTCCTAACATCTGCATATAAGATGTTTAAAATGTTCAGGGGCCCATTCAAAAATATTCCAGCTGATGATTTATATGGTATAAGTGAGCAGTTCTTTACGCCTCTTCTATGGAACGGTCTGTGTACAGAAGACATGCTAACATTATACCAATATCTAGTACAGACATTGCTCCCTAAACAAGTTGAAATAGAAATCCAAGGTGGTGTAGTGACAGCAGCGCAGAGACTTGGCCGATTCATAAGTCCGCCAGATGGAATACATGTTAAAGAAGACTTAGATAAATTGATAAAGATACACGTAACACTCGAAGATGATACAGAATTTAAGGAATACTACCTCCTCATATACAGAACATTGAGTGCGACTGTCTGTTTCACTATTGATGTAAACACTCGGCTGGAACTTGATACGGTCAAGTCAGTGGACGCATTTATTGGGCCGCAGCTATCAGCAATAGCTTCGGCCATCAGCGAACAATGTTCATTGCACGCATTACAAGCAGCGCAACTGGCTAGCGAACACAAGTTCGTGTACTTCAACAGATTAAATTTAATTTTGAAATCATCTCCACCAGTAAATAAATTGCAAATATCCGCTGCGATAAAACCTGAAGTTCTTAGTATCATGTCTGGAATTCATGCTGACCGACAAAGCCTTGGAAATTATGGAGAAATAATAATTAAAACTCCAGACGAATACTGGATAACAGGAAAATGTTCCAATGACAGAGAATTCTATGTGATAATACAAGAGAAAAATGCCAACCTTAAAGAAATAGCGGATGAAGTGAAGCGTGTCTGTGAAGCACAAATGAAAGGGATATTCTTTTACCCTATGTAA

Protein

MIDLRSKINFFFVFNPTFGPKEGDELKRILYFYPNEVSPDARKMQVGLCEAVVKFMSTFSSEPCEALQTQSKRYIFFQPEKNFWMVLVVRIPYTTKALSAVGESQGDIVNPTVMQNLLTSAYKMFKMFRGPFKNIPADDLYGISEQFFTPLLWNGLCTEDMLTLYQYLVQTLLPKQVEIEIQGGVVTAAQRLGRFISPPDGIHVKEDLDKLIKIHVTLEDDTEFKEYYLLIYRTLSATVCFTIDVNTRLELDTVKSVDAFIGPQLSAIASAISEQCSLHALQAAQLASEHKFVYFNRLNLILKSSPPVNKLQISAAIKPEVLSIMSGIHADRQSLGNYGEIIIKTPDEYWITGKCSNDREFYVIIQEKNANLKEIADEVKRVCEAQMKGIFFYPM

Description

Acts in concert with MON1A, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.
Acts in concert with MON1A, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).

Subunit

Interacts with MON1A. Found in a complex with RMC1, CCZ1 MON1A and MON1B.
Interacts with MON1A. Found in a complex with RMC1, CCZ1, MON1A and MON1B.
Interacts with MON1A (PubMed:23084991). Found in a complex with RMC1, CCZ1, MON1A and MON1B (PubMed:29038162).

Similarity

Belongs to the CCZ1 family.

Keywords

Acetylation   Complete proteome   Guanine-nucleotide releasing factor   Lysosome   Membrane   Phosphoprotein   Reference proteome  

Feature

chain  Vacuolar fusion protein CCZ1 homolog

Uniprot

A0A194PWR0   A0A194QU31   A0A3S2N9X2   A0A2H1WXG5   H9J7I8   A0A2A4JEW2   + More
S4NK59   A0A212EL52   A0A0B7A2C9   A0A3L7HQ82   A0A1S3IZ04   A0A067R0N2   D6WEZ5   A0A232FEF7   A0A140UHX9   Q8C1Y8   F7DNC8   A0A1L8EY01   A0A1U7R302   Q28HU2   F7C5J2   F6XPR3   A0A1U7ULN4   A0A1W7RBN4   T1E444   G3IC82   U3FYS6   G1SSD7   E2B812   A0A151N1E6   A0A2K6GIC1   K9ILB0   G3WN95   H0XIL6   A0A1L8EQF7   Q7T102   A0A0B7A1T9   A0A2D4MSQ3   H9GIQ0   A0A250YIR5   G5BF32   G1Q273   I3M786   A0A1B6LR64   Q0VD30   A0A091PT21   W5MPS9   A0A2D4NK71   A0A341BHI4   A0A2U3V336   A0A2Y9P8T5   A0A2Y9SB26   M3X7D0   A0A1V4KS48   A0A087ZSP4   A0A2A3EEL0   F1NPX4   A0A2P4THD5   A0A2Y9J630   Q5ZLN2   A0A226PTA4   A0A093G479   A0A091S9U4   U6D8S8   J3JV42   A0A2Y9DTU4   A0A2J8KJT1   A0A091D499   A0A099ZL34   A0A0Q3XBR0   A0A340WPL3   G1LQY0   A0A3Q7X425   A0A250Y1U2   A0A2K5EJ21   K7BL66   H2QU52   F7AJ87   U3KHS8   A0A3Q7NMA6   H0VRU5   H2RGW5   G2HGQ4   P86791   P86790   A0A2K5PCG3   U3BMT8   A0A2Y9GAB2   H2PLG8   U3BAR2   H9Z9Y4   A0A2K6QQ63   A0A218V7P8   H9H486   H9Z9Y5   H9FVN6   G3TTW3   A0A096NQ31  

Pubmed

26354079    19121390    23622113    22118469    29704459    24845553    + More
18362917    19820115    28648823    15057822    16141072    15489334    19144319    21183079    20431018    27762356    18464734    26358130    23758969    21804562    23915248    21993624    20798317    22293439    21709235    21881562    28087693    21993625    17975172    15592404    15642098    24621616    22516182    20010809    16136131    19892987    21484476    10810093    14702039    12853948    17897319    18220336    18669648    19413330    21269460    23084991    22223895    23186163    29038162    25243066    25319552    25362486    17431167   

EMBL

KQ459595    KPI95570.1    KQ461154    KPJ08500.1    RSAL01000163    RVE45368.1    + More
ODYU01011808    SOQ57765.1    BABH01013921    NWSH01001841    PCG69942.1    GAIX01013429    JAA79131.1    AGBW02014132    OWR42213.1    HACG01027917    CEK74782.1    RAZU01000163    RLQ68066.1    KK852824    KDR15453.1    KQ971319    EFA00460.2    NNAY01000365    OXU28858.1    AC126486    AK090008    AK150793    AK152328    AK152576    AK153160    BC048077    AAMC01007054    AAMC01007055    AAMC01007056    CM004482    OCT64210.1    CR760737    GDAY02002918    JAV48549.1    GAAZ01002916    JAA95027.1    JH001891    EGW02542.1    GAEP01001871    JAB52950.1    GL446270    EFN88171.1    AKHW03004154    KYO30646.1    GABZ01005828    JAA47697.1    AEFK01075610    AEFK01075611    AEFK01075612    AEFK01075613    AEFK01075614    AEFK01075615    AAQR03148892    AAQR03148893    AAQR03148894    AAQR03148895    CM004483    OCT61586.1    BC055965    HACG01027918    CEK74783.1    IACM01117687    LAB35803.1    AAWZ02029387    GFFW01001260    JAV43528.1    JH169911    GEBF01002442    EHB07893.1    JAO01191.1    AAPE02034763    AGTP01102874    GEBQ01013802    JAT26175.1    BC119863    KK678304    KFQ10810.1    AHAT01013702    IACN01006609    LAB46094.1    AANG04004562    LSYS01001700    OPJ87253.1    KZ288266    PBC30148.1    AADN05000376    PPHD01000222    POI35765.1    AJ719702    AWGT02000022    OXB82712.1    KL214745    KFV61602.1    KK813486    KFQ37220.1    HAAF01006484    CCP78308.1    BT127108    AEE62070.1    NBAG03000362    PNI35261.1    KN123370    KFO25323.1    KL896048    KGL83154.1    LMAW01000001    KQL61533.1    ACTA01178351    ACTA01186349    GFFV01002420    JAV37525.1    GABC01000765    GABF01007286    JAA10573.1    JAA14859.1    AC193266    GABC01000764    GABF01007285    GABD01003299    GABD01003298    GABE01009998    JAA10574.1    JAA14860.1    JAA29801.1    JAA34741.1    AGTO01020915    AAKN02032157    AAKN02032158    AAKN02032159    AC192442    AK305918    BAK62912.1    AF151801    AK292326    AC004983    BC132749    BC132751    AC079882    BC010130    GAMS01008908    GAMR01004692    GAMQ01005809    GAMP01002176    JAB14228.1    JAB29240.1    JAB36042.1    JAB50579.1    ABGA01163992    ABGA01163993    NDHI03004471    PNJ01525.1    GAMT01008599    JAB03262.1    JU475946    AFH32750.1    MUZQ01000034    OWK61949.1    JSUE03027732    JSUE03027733    JSUE03027734    JSUE03027735    JSUE03027736    JSUE03027737    JSUE03027738    JSUE03027739    JSUE03027740    JSUE03027741    JU475947    AFH32751.1    JU334942    AFE78695.1    AHZZ02022003   

Proteomes

UP000053268    UP000053240    UP000283053    UP000005204    UP000218220    UP000007151    + More
UP000273346    UP000085678    UP000027135    UP000007266    UP000215335    UP000002494    UP000000589    UP000008143    UP000186698    UP000189706    UP000002279    UP000189704    UP000001075    UP000001811    UP000008237    UP000050525    UP000233160    UP000007648    UP000005225    UP000001646    UP000006813    UP000001074    UP000005215    UP000009136    UP000018468    UP000252040    UP000245320    UP000248483    UP000248484    UP000011712    UP000190648    UP000005203    UP000242457    UP000000539    UP000248482    UP000198419    UP000053875    UP000248480    UP000028990    UP000053641    UP000051836    UP000265300    UP000008912    UP000286642    UP000233020    UP000002277    UP000002281    UP000016665    UP000286641    UP000005447    UP000005640    UP000233040    UP000008225    UP000248481    UP000001595    UP000233200    UP000197619    UP000006718    UP000007646    UP000028761   

PRIDE

H9J7I8    Q8C1Y8    G3IC82    Q0VD30    P86791    P86790    + More

Pfam

PF08217   DUF1712

Interpro

IPR013176   Ccz1       

ProteinModelPortal

A0A194PWR0   A0A194QU31   A0A3S2N9X2   A0A2H1WXG5   H9J7I8   A0A2A4JEW2   + More
S4NK59   A0A212EL52   A0A0B7A2C9   A0A3L7HQ82   A0A1S3IZ04   A0A067R0N2   D6WEZ5   A0A232FEF7   A0A140UHX9   Q8C1Y8   F7DNC8   A0A1L8EY01   A0A1U7R302   Q28HU2   F7C5J2   F6XPR3   A0A1U7ULN4   A0A1W7RBN4   T1E444   G3IC82   U3FYS6   G1SSD7   E2B812   A0A151N1E6   A0A2K6GIC1   K9ILB0   G3WN95   H0XIL6   A0A1L8EQF7   Q7T102   A0A0B7A1T9   A0A2D4MSQ3   H9GIQ0   A0A250YIR5   G5BF32   G1Q273   I3M786   A0A1B6LR64   Q0VD30   A0A091PT21   W5MPS9   A0A2D4NK71   A0A341BHI4   A0A2U3V336   A0A2Y9P8T5   A0A2Y9SB26   M3X7D0   A0A1V4KS48   A0A087ZSP4   A0A2A3EEL0   F1NPX4   A0A2P4THD5   A0A2Y9J630   Q5ZLN2   A0A226PTA4   A0A093G479   A0A091S9U4   U6D8S8   J3JV42   A0A2Y9DTU4   A0A2J8KJT1   A0A091D499   A0A099ZL34   A0A0Q3XBR0   A0A340WPL3   G1LQY0   A0A3Q7X425   A0A250Y1U2   A0A2K5EJ21   K7BL66   H2QU52   F7AJ87   U3KHS8   A0A3Q7NMA6   H0VRU5   H2RGW5   G2HGQ4   P86791   P86790   A0A2K5PCG3   U3BMT8   A0A2Y9GAB2   H2PLG8   U3BAR2   H9Z9Y4   A0A2K6QQ63   A0A218V7P8   H9H486   H9Z9Y5   H9FVN6   G3TTW3   A0A096NQ31  

KEGG

101742995    no KO assigned | (RefSeq) vacuolar fusion protein CCZ1 homolog

GO

GO:0035658   GO:0016192   GO:0016021   GO:0043231   GO:0005085   GO:0005765   GO:0016235   GO:0005829  

PANTHER

PTHR13056  

Subcellular location

Lysosome membrane  

Length:

395

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01385

Exp number, first 60 AAs:

0.00014

Total prob of N-in:

0.01027

outside

1  -  395

 

 

Pi

228.721983

Theta

150.970328

Tajima's D

1.440116

CLR

0

CSRT

0.773061346932653

Interpretation

Uncertain