Gene

KWMTBOMO04573  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005477

Annotation

integrin_alpha-PS1_precursor_[Bombyx_mori]

Location

Bomo_Chr8(+):10164950-10178094      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.126 PlasmaMembrane   Reliability : 1.758

CDS

ATGTACCTGCTATCCGTTAATTGCACCATGTTACTTGTTGGAGCTCCGTTAGATCAAAATCTACAACCGAACACAACAAAGTCTGGCGCTTTGTGGAAATGCAGTCTCAGCCCAGACACGAACGACTGCGAGCAGATTATTACAGACGGGAAACGAACACTGGATTCTGATCATCTATCGGGTCCTTATTCAGACGAGATCAAGGAAGGCCAATGGCTCGGCGTGACTGTTCGAAGTCAGGGTCCTGGCAAAAAGGCTGTAGTTTGTGCTCACAGGTACATTCGAAAGATTGGACAACTGCAATTCGGCCAAGGACTGTGTTACACTTTCAAAAACACTCTACAACTACACGAAATCACTGAACCTTGTAGAGGAAGACCTATTACTAGAGAACACGAAGAATATGGTTTCTGTCAAGTAGGAACAAGCAGTACTCTATTGGATGATGAAACATTAATCCTCGGCAGTCCGGGACCGTATGCCTGGCGAGGAACAATATTCGCACAAGATATGACCGACGAAATGTTTGCCCGAGATAATGTGGTCTATAGTGCACCTGTCACTGATGGTGCTAGTCCTGTCGAGAAATACAGCTACCTGGGAATGTCAGTAGCAGGTGGAATGTTTTTTGGAAACAAGTCCTCTTACGTAGCCGGTGCACCCCGGGCCCAAGGGACTGGTCAAGTTGTAATTTTCAACAAAAAAGACACCGCTGATTGGGGCAGAACGGACTTAGATATTCTTCGTTTTACACTCATTCTGAAAGGGGAACAGTTTGGGTCCAGCTTTGGATATGAAGTGGCCGTGGCTGATGTTAATGGAGATGGATTGCCGGATCTTCTAGTCGGTGCACCATTTTATTTTTCACGAGATGCCGGTGGTGCAGTGTACTTATATCTTAATAAAAATCAAAACTTAACAAAAAAGTTCGATTTAAAGTTGACTGGAAAACAAGAATCACAGTTTGGTATTTCCATTGCTAATGCATCAGACTTAAACAAAGATGGTTGTCAAGATATAGCAATCGGTAGTCCTTACGAAGGGAATGGAGTTGTGTATATTTATATGGGTAACCGTAGAACTGGTTTGAATTCAATACCAGATCAGGTTATTTCAGCTGAAAGCTTACCAATCGTATTGAAGACATTTGGCTACTCGCTTTCAGGGGGTATTGATTTAGATGCTAATGGATATCCTGATTTGTTAGTTGGCGCGTATGAGAATAGCAGCGTCGCTTTAATACGAACGAGACCGATCATTGACATAAAGACGTCAATACGACCATCGAATACTATAATTAATATCGACCCGACGAAGCAGGGCTGTGAAAGAGATCCATCCTCAAAGTATACATGTTTCCACTTTCAAGCCTGCTGTACAATCGAATCTTTGGTGAAATCCACAAAAACGAATGCTCTAAAGTTGAATTATGTAATTGAAGCAGAAACTTTCCTTGGCGGGAAAAGATATTCTAGGGTGTTCTTGGATACAGAAAAGACGAACATAGTTAAAAAGTCAATTGTTCTGGACAAAGAAATCGAAGATTGCAGAGAACACATTGTTTACATAAAAAACAATACAAGAGATATTCAAACCCCAATAAAGTTCCAAGTGACATATAAATTGGAGAATGTCGAGCCGCAATATTCTCCCTCTGGCACTTTGCCCAACATCGATGATTACCCTGTTCTCAATGCGACAGCGATGACAACCTTCAGCGCTCACTTCTTGAACGACTGCGGGACTGATGCGATTTGTGTTAGTAATCTAATCGTCAATCCTGTTTTACAATTACCAAAAACGTCAGATGGCAAGTCGTACGCGCTCACATTAGGCCAAGAGGAAGAAATTAAGCTGTCAATAACTGTAGACAATTATGGGGAGTCAGCATACGAGAGCCAACTTTTCGTACAACACCATTCAAGTTTACATTACATCGCTGCAAATATAAGTGACAAGAACGTGATATGTACGAGTGTCAATAAAACGATAGTATCTTGTATGCTGGAGAATCCTTTCAAGAAGCAGCCGGAAAGTGCGGCTCCCATCACAATGAGGTTCGACGCAAGAGCACTTGAAGACAATGAGCCTTCAGTAGTGTTCACAGTTTGGGCTAATTCTACCTCCAAAGAATTGCACTCTGGGAAGAAGCCGGTTCAAGTCGAAGCCCTTGTAATTAAGAATGCTGAATTACTAATTAAAGGAGCTGCCCGACCAGAACAAGTTTTCTACGGAGGAGATATAAAAGGAGAATCTGCCATGACTTACTTCGATGACGTCGGTACAAGAGTGGTGCATACTTACCAGGTATTCAATGAAGGCCCTTGGCGCGTGTCTTCCGTGCAAGTTGTTATATTGTGGCCACATCAGGTAGCTTCTGAAAACGCACAGGGCAAATGGCTACTGTATCCCGAAGATGTTCCTACCGTCGACGGCGAAGCTGACCAGAGTAATGGTGAGTGCTTTATCACAGAAAAAGAGATTAACCCCTTAAACCTGACGTCCAGACCTGGAACATTTGAGCCTTATTTAGAAAACTTGGAGATAAATCCATTCATGAGTACTGGAAAGATCAGCGTGAACTCTTATGAAAAACAACAAAATCAAAGTAAAGTTGTAGAATTATCTACTGCCAAGGAAAATAAAGTGAGAAGAAAAAGAGATAGTGACGTAGTTAAAGCCGAAGCATATACGGACAAAGATGGGCAGAGAAAACATGTGGTTAATATGAGCTGCCAAAAGAAGACAGCGAAGTGCATACAATTTCAATGCGTGATCTATCGACTATCTCGGGCTCAGGCCACAACCATTACTGTGAAGGCTCGACTTTGGAACGCTACACTAGTAGAAGATTATCCCCGAATCAGCCATGTCAACATCGCTTCTACTGCGTTCATACATATACCAGATCACTACAACATCCATCAAAGCAAACAACACGATGATACCGCCACGGTTGAAACAGTCGCATATCCGGATTTGAAGATCAGCGAGCCCACAGAAGTTCCTCTTTGGGTCATCATTATATCAGTAATTATTGGACTAATCGTTCTGATACTCCTCATCTTAGCCCTTTGGAAACTGGGCTTCTTCAAGAGAAGTCGTCCTGACCCTACTCTCTCAGGAAACTTGGAGAAAAACCACCACGAATCCAGTCCGTTCATAGGAAGAGATAGAAATAGCATTCGATAG

Protein

MYLLSVNCTMLLVGAPLDQNLQPNTTKSGALWKCSLSPDTNDCEQIITDGKRTLDSDHLSGPYSDEIKEGQWLGVTVRSQGPGKKAVVCAHRYIRKIGQLQFGQGLCYTFKNTLQLHEITEPCRGRPITREHEEYGFCQVGTSSTLLDDETLILGSPGPYAWRGTIFAQDMTDEMFARDNVVYSAPVTDGASPVEKYSYLGMSVAGGMFFGNKSSYVAGAPRAQGTGQVVIFNKKDTADWGRTDLDILRFTLILKGEQFGSSFGYEVAVADVNGDGLPDLLVGAPFYFSRDAGGAVYLYLNKNQNLTKKFDLKLTGKQESQFGISIANASDLNKDGCQDIAIGSPYEGNGVVYIYMGNRRTGLNSIPDQVISAESLPIVLKTFGYSLSGGIDLDANGYPDLLVGAYENSSVALIRTRPIIDIKTSIRPSNTIINIDPTKQGCERDPSSKYTCFHFQACCTIESLVKSTKTNALKLNYVIEAETFLGGKRYSRVFLDTEKTNIVKKSIVLDKEIEDCREHIVYIKNNTRDIQTPIKFQVTYKLENVEPQYSPSGTLPNIDDYPVLNATAMTTFSAHFLNDCGTDAICVSNLIVNPVLQLPKTSDGKSYALTLGQEEEIKLSITVDNYGESAYESQLFVQHHSSLHYIAANISDKNVICTSVNKTIVSCMLENPFKKQPESAAPITMRFDARALEDNEPSVVFTVWANSTSKELHSGKKPVQVEALVIKNAELLIKGAARPEQVFYGGDIKGESAMTYFDDVGTRVVHTYQVFNEGPWRVSSVQVVILWPHQVASENAQGKWLLYPEDVPTVDGEADQSNGECFITEKEINPLNLTSRPGTFEPYLENLEINPFMSTGKISVNSYEKQQNQSKVVELSTAKENKVRRKRDSDVVKAEAYTDKDGQRKHVVNMSCQKKTAKCIQFQCVIYRLSRAQATTITVKARLWNATLVEDYPRISHVNIASTAFIHIPDHYNIHQSKQHDDTATVETVAYPDLKISEPTEVPLWVIIISVIIGLIVLILLILALWKLGFFKRSRPDPTLSGNLEKNHHESSPFIGRDRNSIR

Subunit

Heterodimer of an alpha and a beta subunit.

Similarity

Belongs to the integrin alpha chain family.

Uniprot

A0A076JVB3   H9J7I5   A0A212ES31   A0A194PNQ1   A0A2H1VCY1   A0A1E1WRC4   + More
A0A2A4JVZ9   A0A194QU26   Q86G88   A0A1E1WLE5   A0A0L7LQM8   A0A067QUQ4   A0A1L8E400   A0A1L8E3C4   A0A1L8E3J4   A0A026VUY3   A0A1B0GKX3   A0A2A3ECL3   A0A3L8DE97   F4X5Q1   A0A195FQK3   A0A088ACX9   A0A154P056   A0A310STA2   A0A0P5N3H1   A0A0N8BB58   A0A0P6GVW7   A0A0P4ZC31   E9HAH4   A0A0P5C057   A0A0P4XX18   A0A0N8CM66   A0A0N8BWE9   A0A195BWJ3   A0A0N8AZ48   A0A0P5QID4   A0A0P5WQL9   A0A336MNG2   A0A0P5BL96   A0A0P6E5F6   A0A0P5PI39   A0A0P5U4M3   A0A0P5SDM2   A0A0P5JRM0   A0A0P5XJS3   U5EVI2   A0A0P5WI39   A0A0P5K412   A0A0P5Q316   A0A1I8PI49   A0A0P5HVX7   A0A0P6CIX5   A0A0P5UWB3   A0A0N8BHX1   A0A2S2PBV2   A0A336L6N5   A0A0P5N2F5   A0A0P6GQH3   A0A0P5DE29   A0A0P5MWQ1   A0A0P5VQV1   A0A2H8TNL6   A0A195CPU1   A0A0P5UL62   A0A158NUX1   J9JMY8   A0A0P5S3D5   A0A0P5N233   A0A0P5SED1   W8B5Q2   A0A2S2QN44   A0A0P5EBY2   A0A0A1WM48   A0A0L0CB15   A0A0P6E034   A0A0P5MRB7   A0A0P6ENK1   A0A0P5S3D1   A0A0A1XIX7   A0A0P6AZ93   A0A232EN93   A0A0P6JTB9   A0A1Q3FLP0   A0A1Q3FLJ8   A0A1Q3FLB2   A0A1Q3FLM6   A0A1Q3FLM1   A0A1Q3FLL8   A0A023EWP9   E9IJA6   A0A0P5P545   B0W7R8   E2B0Y4   A0A1J1IC26   A0A1Q3FLG3   A0A1Q3FLU3   Q17KN9   A0A1Q3FLL7   A0A1Q3FLN6  

Pubmed

25064490    19121390    22118469    26354079    12974949    26227816    + More
24845553    24508170    30249741    21719571    21292972    21347285    24495485    25830018    26108605    28648823    24945155    21282665    20798317    17510324   

EMBL

KJ511849    AII79408.1    BABH01013908    AGBW02012896    OWR44261.1    KQ459599    + More
KPI94369.1    ODYU01001858    SOQ38646.1    GDQN01001494    JAT89560.1    NWSH01000571    PCG75570.1    KQ461154    KPJ08495.1    AY237585    AAO85803.1    GDQN01003259    JAT87795.1    JTDY01000323    KOB77704.1    KK853387    KDR07962.1    GFDF01000819    JAV13265.1    GFDF01000928    JAV13156.1    GFDF01000781    JAV13303.1    KK108839    EZA46609.1    AJWK01033902    KZ288285    PBC29468.1    QOIP01000009    RLU18616.1    GL888739    EGI58217.1    KQ981335    KYN42577.1    KQ434787    KZC05299.1    KQ760551    OAD59829.1    GDIQ01155257    JAK96468.1    GDIQ01194995    JAK56730.1    GDIQ01038349    JAN56388.1    GDIP01214610    JAJ08792.1    GL732612    EFX71180.1    GDIP01181316    GDIP01146221    GDIQ01162407    GDIP01069736    GDIQ01029605    JAJ42086.1    JAK89318.1    GDIP01236830    JAI86571.1    GDIP01118119    JAL85595.1    GDIQ01138267    JAL13459.1    KQ976401    KYM92650.1    GDIQ01228675    JAK23050.1    GDIQ01120213    JAL31513.1    GDIP01082984    JAM20731.1    UFQS01001739    UFQT01001739    SSX12129.1    SSX31590.1    GDIP01197920    JAJ25482.1    GDIP01146223    GDIP01050735    GDIQ01067840    JAJ77179.1    JAN26897.1    GDIQ01138266    JAL13460.1    GDIP01118121    JAL85593.1    GDIQ01095026    JAL56700.1    GDIQ01194994    JAK56731.1    GDIP01071331    JAM32384.1    GANO01001848    JAB58023.1    GDIP01086133    JAM17582.1    GDIQ01194996    JAK56729.1    GDIQ01120214    JAL31512.1    GDIQ01228074    JAK23651.1    GDIQ01090474    JAN04263.1    GDIP01107386    JAL96328.1    GDIQ01176091    JAK75634.1    GGMR01014243    MBY26862.1    SSX12128.1    SSX31589.1    GDIQ01147972    JAL03754.1    GDIQ01031151    JAN63586.1    GDIP01157716    JAJ65686.1    GDIQ01152408    JAK99317.1    GDIP01096788    JAM06927.1    GFXV01003930    MBW15735.1    KQ977444    KYN02758.1    GDIP01113680    JAL90034.1    ADTU01026806    ADTU01026807    ADTU01026808    ABLF02022377    ABLF02022379    GDIQ01092928    JAL58798.1    GDIQ01152407    JAK99318.1    GDIQ01092930    JAL58796.1    GAMC01021441    JAB85114.1    GGMS01009767    MBY78970.1    GDIP01162510    JAJ60892.1    GBXI01014168    GBXI01011409    GBXI01000867    JAD00124.1    JAD02883.1    JAD13425.1    JRES01000755    KNC28664.1    GDIQ01070438    JAN24299.1    GDIQ01152406    JAK99319.1    GDIQ01073182    JAN21555.1    GDIQ01092929    JAL58797.1    GBXI01003457    JAD10835.1    GDIP01022314    JAM81401.1    NNAY01003194    OXU19825.1    GDIQ01009218    JAN85519.1    GFDL01006590    JAV28455.1    GFDL01006651    JAV28394.1    GFDL01006645    JAV28400.1    GFDL01006621    JAV28424.1    GFDL01006610    JAV28435.1    GFDL01006637    JAV28408.1    GAPW01000065    JAC13533.1    GL763764    EFZ19346.1    GDIQ01133477    JAL18249.1    DS231855    EDS38212.1    GL444716    EFN60653.1    CVRI01000044    CRK96534.1    GFDL01006624    JAV28421.1    GFDL01006557    JAV28488.1    CH477222    EAT47265.1    GFDL01006623    JAV28422.1    GFDL01006554    JAV28491.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000218220    UP000053240    UP000037510    + More
UP000027135    UP000053097    UP000092461    UP000242457    UP000279307    UP000007755    UP000078541    UP000005203    UP000076502    UP000000305    UP000078540    UP000095300    UP000078542    UP000005205    UP000007819    UP000037069    UP000215335    UP000002320    UP000000311    UP000183832    UP000008820   

PRIDE

H9J7I5   

Pfam

PF08441   Integrin_alpha2        + More
PF01839   FG-GAP

Interpro

IPR032695   Integrin_dom_sf        + More
IPR018184   Integrin_alpha_C_CS       
IPR028994   Integrin_alpha_N       
IPR013517   FG-GAP       
IPR013519   Int_alpha_beta-p       
IPR000413   Integrin_alpha       
IPR013649   Integrin_alpha-2       

SUPFAM

SSF69179   SSF69179       

Gene 3D

2.130.10.130    

ProteinModelPortal

A0A076JVB3   H9J7I5   A0A212ES31   A0A194PNQ1   A0A2H1VCY1   A0A1E1WRC4   + More
A0A2A4JVZ9   A0A194QU26   Q86G88   A0A1E1WLE5   A0A0L7LQM8   A0A067QUQ4   A0A1L8E400   A0A1L8E3C4   A0A1L8E3J4   A0A026VUY3   A0A1B0GKX3   A0A2A3ECL3   A0A3L8DE97   F4X5Q1   A0A195FQK3   A0A088ACX9   A0A154P056   A0A310STA2   A0A0P5N3H1   A0A0N8BB58   A0A0P6GVW7   A0A0P4ZC31   E9HAH4   A0A0P5C057   A0A0P4XX18   A0A0N8CM66   A0A0N8BWE9   A0A195BWJ3   A0A0N8AZ48   A0A0P5QID4   A0A0P5WQL9   A0A336MNG2   A0A0P5BL96   A0A0P6E5F6   A0A0P5PI39   A0A0P5U4M3   A0A0P5SDM2   A0A0P5JRM0   A0A0P5XJS3   U5EVI2   A0A0P5WI39   A0A0P5K412   A0A0P5Q316   A0A1I8PI49   A0A0P5HVX7   A0A0P6CIX5   A0A0P5UWB3   A0A0N8BHX1   A0A2S2PBV2   A0A336L6N5   A0A0P5N2F5   A0A0P6GQH3   A0A0P5DE29   A0A0P5MWQ1   A0A0P5VQV1   A0A2H8TNL6   A0A195CPU1   A0A0P5UL62   A0A158NUX1   J9JMY8   A0A0P5S3D5   A0A0P5N233   A0A0P5SED1   W8B5Q2   A0A2S2QN44   A0A0P5EBY2   A0A0A1WM48   A0A0L0CB15   A0A0P6E034   A0A0P5MRB7   A0A0P6ENK1   A0A0P5S3D1   A0A0A1XIX7   A0A0P6AZ93   A0A232EN93   A0A0P6JTB9   A0A1Q3FLP0   A0A1Q3FLJ8   A0A1Q3FLB2   A0A1Q3FLM6   A0A1Q3FLM1   A0A1Q3FLL8   A0A023EWP9   E9IJA6   A0A0P5P545   B0W7R8   E2B0Y4   A0A1J1IC26   A0A1Q3FLG3   A0A1Q3FLU3   Q17KN9   A0A1Q3FLL7   A0A1Q3FLN6  

PDB

6DJP     E-value=3.03888e-77,     Score=738

KEGG

101747051    K06583 integrin alpha 7 | (RefSeq) integrin alpha-PS1

PATHWAY

04512    ECM-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0008305   GO:0007155   GO:0007229   GO:0016021   GO:0006457   GO:0042626   GO:0016887   GO:0007165   GO:0015031   GO:0016020   GO:0016742   GO:0003824  

Subcellular location

Membrane  

SignalP

Position:   1 - 16,         Likelihood:  0.627674

 

 

Length:

1063

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.91585

Exp number, first 60 AAs:

0.00345

Total prob of N-in:

0.00036

outside

1  -  1003

TMhelix

1004  -  1026

inside

1027  -  1063

 

 

Pi

221.993945

Theta

173.259914

Tajima's D

0.897456

CLR

0.001338

CSRT

0.630868456577171

Interpretation

Uncertain