Gene

KWMTBOMO04554  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005338

Annotation

PREDICTED:_ubiquitin_conjugation_factor_E4_A_isoform_X2_[Papilio_machaon]

Location

Bomo_Chr8(-):9613821-9628846      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.377 Nuclear   Reliability : 1.303 PlasmaMembrane   Reliability : 1.08

CDS

ATGTCTCAACAGTTTAATCCATTTCTTGGGTTACTGGGAACTTCTCCATCTGAAACTCCAATTCCGGAAGACAGTCCTATAACTATTACTTCTGTGCCAGTCCAGGTTGATGAAGAAACAGAAATTGTAAACAACATCGTCGAAAATGTTTTTTACTTTACCATAAATGTAAATGCAGTCGAAAATCGGCCCAATAATGAAAAACAGTTAGTATATTTAGAAGAACTTGCTGAAGCAACTAAACCTCGCATTCACATAGACTTCGAAGCATTGGAACAGGCACTTTTCGAAAGATTACTTTTGCAAGATGTTGAGTCTAATGTTATTCCAAAAGGTACCAAAGTTTATAAGGAGCATGTCATAGAGAAGCATGTCTTTCTGTATCTATTTAACTCCTTACAAAATCTACAAAGTTATAACAATAGCAAGAACATGGTGGAAAAGCGAGCTGTGTCAAAAATGAGAGAATTAATATTTCGAAATGCAGTGACTGCTTTAAAACAACCAGCACTCTTTGAAGACCAAGACTTTTCATCACAGCTTTTAGGATTATTACAACATGCTGACCCATTGAGTCAATCATTTTTTACTGATATTGTCAATGCACTGGTATCCGATTGTGATAATGAAAGTCAAGCACAACTTAAAGCCACAATGAATGAGGTTCTGCAAAAAATTAATACAGAAGTAAAGAAGTCTAATTTAATCAATCTACCGAATTATATTTTACCATCTGTACATTTATTTGCTAGTAACCCTCATTTAGCACCAATTTTAATGGAAGAAAGTGAGCCAAAAGTAGAAAATAATGGACGTTTGTATCAAGACTCAGTTATTGGTGCTCTTCTGAGTTTGTCGGTTCTACCTAGAACTGCCTTATCACTTCATGAATTCTTTGAACAACCAATGGATCAGGCAGCCAACTCATTAATAGAAACCTCAATATGGAATGCATTGTCACATTTAAACAATAATATGCAAAGAATATTTCTGGGGCTGTTGAAATGTGGACCTGCGATGCGTAATCGTCTACTCACTTGGACCGGTAAATGTTTGAGTGCGAATGTAGCAAGAGGAAAACTGTGGAGTGTACAAGCTGGAGAAATCAGTGCTGCAACACTGAACTGCGTGTCCGACGGCTTCATGTTGAACCTGGGTGCAGTGTTATTGCAACTTTGTATGCCATTCTGTGCCTCCCCAGATGACCCTAAATTACTTAAAATAGATCCAACTTACGGAGCTGTTCCGCCCGAGGAATGTGCCTCGAAATCTGTTCATCTCGACAGCCTACATAATGAAACGTGCTTATTACCACCACGAGAAGACGAAAACGGACAATCTATAAAACGACCGACGGCCGAAACATATAGTTTCGTAACTGAATGTTTCTTTGTGACACAGAAATGTATCGATTTGGGTGTACGCGTCTGCGCCGAGAAGCTATGGCAGTGCGGTCGCGAGCTCGGGCAGGCCCAGCGCGCCCTCGCCGACGCCGGCACCGCGCCGCGCCTGCTCGAAGCCCTACGCACTCGCACGCATCATCTCATGACGCGGTTTGTTAGTCTGCGTTGCGCTTTACTAGAGAAGAACATGTTGACGAATTTGCATCGGCTTCAAGCGGCGACTTGCACGTGGCTCGTACAAGTGGCGATACGGACCGATCTGGACACGCCGCTCAGTAACTACGCGCCCATGACCCTACTGCCGGTCGAGATGCCCATAACCACACCAGCACCCGACACGCTAAGATGCATTCCAGAGTTCGTATTGGAAAATATAGTGGTTTTAATAACAATGGCGCGACGCACCGCCGGAGCTACGACCGAAGAAGCAGACATCGCTGGCCTGCTGCAGCCCGCGCTCACCCTCGTGCTCACGTTCATGGGAGACTCCTCGCGTACTTACAACCCGCATCTGAGGGCACGACTAGCTGAATGTCTGGAAGCGATGCTGCCTAATCATCCAGACAACCAACAGCCTTTAAGTAGTTTGGCTTCGTTTTACAGAGAACAACTCTTCAAAGAACATCCTCACAGATCACAGCTCGTGCCATGCCTTTTGGATGTATTCGTGGGCATAGAAATGACCGGACAGAGTGTTCAGTTTGAACAAAAGTTCAACTACCGTCGACCCATGTACCTTGTCATGGAATTCCTATGGGGACTGGAAGAACACCGGGAATCTTTTAGTCAATTAGCAAGAGAAGCAGAATCCAATATGGAGGCTGTACATCCACCGATATTTTTGCGTTTCGTCAATCTGTTGATGAACGACGCTATATTCTTACTGGATGAAGCATTAGGGAACATGGCTCAAATAAGAACTATGCAAACTGCACAACAATCCGGTGCGTGGAGGAACTTGCCGGTTCACGAACGCGAACAAAACTTCTCGAATTTATCTCACATCGGGATGTTGGCGCGCTTCGACAATATACTCGGGCGCGACACGATCCGCATGCTGGTGCGGCTCACCGCGCACGCGCCGCACGTGTTCTGTCACCCGACGCTCGTCGACCGGATCGCGTCGATGCTCAACTACTTCCTGCTGAACCTGGTCGGACCTAACAAAAAGAATTTGAAAGTAAAAGACATGAAGGAATACGAGTTCGACCCGGCCAGTACAGTGCTGGACATTTGTCGTATGTACGTGGAGCTAGGTAACAACGAGCGGTTCTGCAACGCCGTGTCCGACGACGGCCGCTCCTACTCGCCGCAACTGTTCACCCTCGCTGAAACTGTACTAGTCCGCATCGGGGGGGGCTTTCTCATAAGCACACTGCGGGAGGTTGCCGAGCGAGTGAGACTGCTCGCCGAACAGAAGCAGAGAGACGAGGAGATACTCGCGAACGCTCCAGACGAGTTCCTCGATCCGATCATGAGCACCATCATGCTGGACCCCGTCGTGCTTCCGAGCTCAAGGACCACGGTCGACAGGACGACAATAGCCAGGCATCTTTTAAGTGATCAGTCAGATCCATTCAACAGGTCGCCGCTCTCCATGGATCAAGTAAAATCAGACACTGAACTCAAAGAAAGAATACACAGCTGGATCGCTGAAGCCAAAAAGAATAGTTCACAATCGACGAGCACTAAAAATTAG

Protein

MSQQFNPFLGLLGTSPSETPIPEDSPITITSVPVQVDEETEIVNNIVENVFYFTINVNAVENRPNNEKQLVYLEELAEATKPRIHIDFEALEQALFERLLLQDVESNVIPKGTKVYKEHVIEKHVFLYLFNSLQNLQSYNNSKNMVEKRAVSKMRELIFRNAVTALKQPALFEDQDFSSQLLGLLQHADPLSQSFFTDIVNALVSDCDNESQAQLKATMNEVLQKINTEVKKSNLINLPNYILPSVHLFASNPHLAPILMEESEPKVENNGRLYQDSVIGALLSLSVLPRTALSLHEFFEQPMDQAANSLIETSIWNALSHLNNNMQRIFLGLLKCGPAMRNRLLTWTGKCLSANVARGKLWSVQAGEISAATLNCVSDGFMLNLGAVLLQLCMPFCASPDDPKLLKIDPTYGAVPPEECASKSVHLDSLHNETCLLPPREDENGQSIKRPTAETYSFVTECFFVTQKCIDLGVRVCAEKLWQCGRELGQAQRALADAGTAPRLLEALRTRTHHLMTRFVSLRCALLEKNMLTNLHRLQAATCTWLVQVAIRTDLDTPLSNYAPMTLLPVEMPITTPAPDTLRCIPEFVLENIVVLITMARRTAGATTEEADIAGLLQPALTLVLTFMGDSSRTYNPHLRARLAECLEAMLPNHPDNQQPLSSLASFYREQLFKEHPHRSQLVPCLLDVFVGIEMTGQSVQFEQKFNYRRPMYLVMEFLWGLEEHRESFSQLAREAESNMEAVHPPIFLRFVNLLMNDAIFLLDEALGNMAQIRTMQTAQQSGAWRNLPVHEREQNFSNLSHIGMLARFDNILGRDTIRMLVRLTAHAPHVFCHPTLVDRIASMLNYFLLNLVGPNKKNLKVKDMKEYEFDPASTVLDICRMYVELGNNERFCNAVSDDGRSYSPQLFTLAETVLVRIGGGFLISTLREVAERVRLLAEQKQRDEEILANAPDEFLDPIMSTIMLDPVVLPSSRTTVDRTTIARHLLSDQSDPFNRSPLSMDQVKSDTELKERIHSWIAEAKKNSSQSTSTKN

Uniprot

A0A2W1C2N5   A0A2A4IYX9   A0A2H1UZW1   A0A194PM27   A0A194QU11   A0A212F462   + More
A0A067QPB5   A0A2J7QP27   A0A1Y1K3I1   D6WFJ1   A0A0C9QY62   A0A2A3E3C9   A0A088A3N0   A0A151X6V8   A0A158NSZ7   A0A0T6AW29   A0A232FKS0   A0A195CB06   A0A151I3Y9   A0A2S2Q4K6   A0A195FES3   F4WY58   K7IRY3   A0A1B6FPW6   A0A2R4SE34   A0A195EGF8   A0A026WCX2   E0VTU5   E2AKX1   A0A0P6IUR8   A0A0M9A9A1   E2BI54   A0A182JUS9   A0A182J8H8   A0A1B0FYA7   J9JLB6   A0A0P4VYL6   A0A336MGD6   A0A336LVS4   U5EIQ4   T1HX59   A0A1L8DTB6   A0A224XHP5   A0A182PSM7   A0A2P8Z9X9   A0A182MSU7   A0A182Y3P4   A0A2M4BBU0   A0A182VZI4   A0A182FNF9   A0A069DZP3   A0A0A9YW70   A0A146L1T6   A0A2M3Z264   A0A182UKF4   A0A182RAR9   A0A154NYH5   A0A2M4AKK2   W5JBL2   A0A182VNL0   A0A182NRX8   A0A182L9Z3   F7IUQ9   Q7PUV9   A0A182HLJ6   A0A182WSP4   A0A1B6C5Z5   A0A182QKU1   A0A2M4BBS0   A0A182HCH6   A0A1Q3FGR2   A0A1Q3FGN4   B0W2D1   B4MZC8   A0A1J1I0T3   A0A0M4E8T3   B4KJT7   B4GJ22   Q29JW1   B4LRE9   A0A0Q9WMQ9   B4JPT2   A0A3B0K110   A0A0R3NV21   A0A0K8UC82   A0A034VDD6   A0A034VFQ4   A0A0A1X098   A0A0L0BSM8   B3MKU1   W8AZT6   B4Q4Z7   Q9U4F8   B4HXV5   A0A1W4UQG8   B3N5U8   B4P0A4  

Pubmed

28756777    26354079    22118469    24845553    28004739    18362917    + More
19820115    21347285    28648823    21719571    20075255    24508170    30249741    20566863    20798317    26999592    27129103    29403074    25244985    26334808    25401762    26823975    20920257    23761445    20966253    15944077    12364791    14747013    17210077    26483478    17994087    18057021    15632085    23185243    25348373    25830018    26108605    24495485    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304   

EMBL

KZ149904    PZC78403.1    NWSH01004628    PCG64839.1    ODYU01000039    SOQ34137.1    + More
KQ459599    KPI94382.1    KQ461154    KPJ08480.1    AGBW02010434    OWR48524.1    KK853109    KDR11245.1    NEVH01012097    PNF30331.1    GEZM01096201    JAV55061.1    KQ971328    EEZ99810.1    GBYB01005622    JAG75389.1    KZ288403    PBC26215.1    KQ982476    KYQ56049.1    ADTU01025462    LJIG01022662    KRT79375.1    NNAY01000103    OXU30937.1    KQ978023    KYM98044.1    KQ976472    KYM83991.1    GGMS01003453    MBY72656.1    KQ981636    KYN38888.1    GL888439    EGI60815.1    GECZ01017527    JAS52242.1    MF101764    AVZ46901.1    KQ978957    KYN27323.1    KK107309    QOIP01000011    EZA52894.1    RLU17280.1    DS235773    EEB16801.1    GL440425    EFN65888.1    GDUN01001037    JAN94882.1    KQ435724    KOX78489.1    GL448450    EFN84625.1    AJVK01000943    ABLF02025495    ABLF02025508    ABLF02051708    GDKW01000882    JAI55713.1    UFQT01001009    SSX28471.1    UFQS01000234    UFQT01000234    SSX01774.1    SSX22152.1    GANO01002539    JAB57332.1    ACPB03011001    ACPB03011002    GFDF01004447    JAV09637.1    GFTR01008446    JAW07980.1    PYGN01000132    PSN53313.1    AXCM01000263    GGFJ01001349    MBW50490.1    GBGD01000290    JAC88599.1    GBHO01007160    GBRD01008400    JAG36444.1    JAG57421.1    GDHC01016115    JAQ02514.1    GGFM01001876    MBW22627.1    KQ434783    KZC04725.1    GGFK01007998    MBW41319.1    ADMH02001966    ETN60154.1    CR954256    CAJ14148.1    AAAB01008987    EAA00913.6    APCN01000909    GEDC01028375    GEDC01026223    JAS08923.1    JAS11075.1    AXCN02000252    GGFJ01001348    MBW50489.1    JXUM01033185    JXUM01033186    KQ560980    KXJ80153.1    GFDL01008320    JAV26725.1    GFDL01008383    JAV26662.1    DS231826    EDS28677.1    CH963913    EDW77401.1    CVRI01000021    CRK91993.1    CP012523    ALC38476.1    CH933807    EDW12540.1    KRG03281.1    CH479184    EDW37336.1    CH379062    EAL32850.2    KRT05010.1    CH940649    EDW64619.2    KRF81749.1    CH916372    EDV98912.1    OUUW01000006    SPP81530.1    KRT05009.1    GDHF01028085    GDHF01005263    JAI24229.1    JAI47051.1    GAKP01017641    JAC41311.1    GAKP01017638    JAC41314.1    GBXI01010092    JAD04200.1    JRES01001533    KNC22229.1    CH902620    EDV31622.1    GAMC01012215    JAB94340.1    CM000361    CM002910    EDX03989.1    KMY88567.1    AF181657    AE014134    AAD55442.1    AAF52416.2    CH480818    EDW51885.1    CH954177    EDV59107.1    CM000157    EDW87862.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000007151    UP000027135    UP000235965    + More
UP000007266    UP000242457    UP000005203    UP000075809    UP000005205    UP000215335    UP000078542    UP000078540    UP000078541    UP000007755    UP000002358    UP000078492    UP000053097    UP000279307    UP000009046    UP000000311    UP000053105    UP000008237    UP000075881    UP000075880    UP000092462    UP000007819    UP000015103    UP000075885    UP000245037    UP000075883    UP000076408    UP000075920    UP000069272    UP000075902    UP000075900    UP000076502    UP000000673    UP000075903    UP000075884    UP000075882    UP000007062    UP000075840    UP000076407    UP000075886    UP000069940    UP000249989    UP000002320    UP000007798    UP000183832    UP000092553    UP000009192    UP000008744    UP000001819    UP000008792    UP000001070    UP000268350    UP000037069    UP000007801    UP000000304    UP000000803    UP000001292    UP000192221    UP000008711    UP000002282   

PRIDE

Q9U4F8   

Pfam

PF10408   Ufd2P_core        + More
PF04564   U-box

Interpro

IPR003613   Ubox_domain        + More
IPR019474   Ub_conjug_fac_E4_core       
IPR013083   Znf_RING/FYVE/PHD       
IPR016024   ARM-type_fold       
IPR000048   IQ_motif_EF-hand-BS       

SUPFAM

SSF48371   SSF48371       

Gene 3D

3.30.40.10    

ProteinModelPortal

A0A2W1C2N5   A0A2A4IYX9   A0A2H1UZW1   A0A194PM27   A0A194QU11   A0A212F462   + More
A0A067QPB5   A0A2J7QP27   A0A1Y1K3I1   D6WFJ1   A0A0C9QY62   A0A2A3E3C9   A0A088A3N0   A0A151X6V8   A0A158NSZ7   A0A0T6AW29   A0A232FKS0   A0A195CB06   A0A151I3Y9   A0A2S2Q4K6   A0A195FES3   F4WY58   K7IRY3   A0A1B6FPW6   A0A2R4SE34   A0A195EGF8   A0A026WCX2   E0VTU5   E2AKX1   A0A0P6IUR8   A0A0M9A9A1   E2BI54   A0A182JUS9   A0A182J8H8   A0A1B0FYA7   J9JLB6   A0A0P4VYL6   A0A336MGD6   A0A336LVS4   U5EIQ4   T1HX59   A0A1L8DTB6   A0A224XHP5   A0A182PSM7   A0A2P8Z9X9   A0A182MSU7   A0A182Y3P4   A0A2M4BBU0   A0A182VZI4   A0A182FNF9   A0A069DZP3   A0A0A9YW70   A0A146L1T6   A0A2M3Z264   A0A182UKF4   A0A182RAR9   A0A154NYH5   A0A2M4AKK2   W5JBL2   A0A182VNL0   A0A182NRX8   A0A182L9Z3   F7IUQ9   Q7PUV9   A0A182HLJ6   A0A182WSP4   A0A1B6C5Z5   A0A182QKU1   A0A2M4BBS0   A0A182HCH6   A0A1Q3FGR2   A0A1Q3FGN4   B0W2D1   B4MZC8   A0A1J1I0T3   A0A0M4E8T3   B4KJT7   B4GJ22   Q29JW1   B4LRE9   A0A0Q9WMQ9   B4JPT2   A0A3B0K110   A0A0R3NV21   A0A0K8UC82   A0A034VDD6   A0A034VFQ4   A0A0A1X098   A0A0L0BSM8   B3MKU1   W8AZT6   B4Q4Z7   Q9U4F8   B4HXV5   A0A1W4UQG8   B3N5U8   B4P0A4  

PDB

2QJ0     E-value=9.28239e-57,     Score=562

KEGG

101746071    K10596 ubiquitin conjugation factor E4 A [EC:2.3.2.27] | (RefSeq) ubiquitin conjugation factor E4 A

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0034450   GO:0000151   GO:0006511   GO:0030433   GO:0000209   GO:0005737   GO:0005634   GO:0005488   GO:0016567   GO:0004842   GO:0008565   GO:0015031   GO:0016020   GO:0016742   GO:0003824  

Length:

1033

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06067

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00009

outside

1  -  1033

 

 

Pi

244.706647

Theta

174.780561

Tajima's D

1.300724

CLR

0

CSRT

0.738913054347283

Interpretation

Uncertain