Gene

KWMTBOMO04535

Annotation

PREDICTED:_NADH_dehydrogenase_[ubiquinone]_1_alpha_subcomplex_subunit_6-like_[Amyelois_transitella]

Location

Bomo_Chr8(+):9346097-9347314      View in EpiBrowser

Full name

Peptidyl-prolyl cis-trans isomerase      

Location in the cell

Cytoplasmic   Reliability : 2.282

CDS

ATGGTTAAACATTTCGATATACCGAAGAGTGAGGAAGATTGTCGATGGAAACTCAGAGAATATTTCTATAGAAATGCTTGTGTAACTGATATACGTGTTATAGACATGTTGGTGATTAAGGGTTACATGGAACTAAAAGAAATGAAACATATGTGGCAACAAAAAGGTCACGTGATGGCGCATTGGAATCCTACACTTGAACCAAAGCCTTATGACTTTATTGGAAAATTTCTAGAAGGGATCGATTAA

Protein

MVKHFDIPKSEEDCRWKLREYFYRNACVTDIRVIDMLVIKGYMELKEMKHMWQQKGHVMAHWNPTLEPKPYDFIGKFLEGID

Description

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Similarity

Belongs to the complex I LYR family.
Belongs to the tetraspanin (TM4SF) family.
Belongs to the cyclophilin-type PPIase family.

Uniprot

A0A2H1VYZ8   A0A2W1BTJ8   A0A3S2LDS0   A0A194QSG3   A0A212EJF7   A0A212EJF9   + More
N6U0D3   A0A0L7LVH4   U4U7N1   A0A1E1W373   S4P9V1   A0A194PLT7   I4DK69   A0A194QSJ9   A0A2W1BYS3   H9J7H0   A0A2H1VYZ0   B4LJC1   A0A0K8V405   A0A034VMX7   A0A2J7QDN1   B4JVZ0   A0A1B0C5E2   A0A182RJ79   A0A023EDZ8   Q17Q29   A0A1A9YL53   A0A1A9URC8   A0A182GAU6   A0A1B0CJY0   A0A0M4ETG2   A0A182IKX4   A0A182VXQ7   A0A1A9Z2G6   A0A1B0FK01   A0A182XXA2   A0A1Q3FL65   A0A182KFR6   A0A1A9WWU7   Q28ZU9   A0A182QQJ1   A0A182PBG8   A0A182KK73   A0A182XKF2   W5JGV3   A0A182NLA0   D1FQ06   B0WQF7   Q7QM15   W8C2I8   A0A1B0CZR5   A0A1L8E0P9   A0A182UXX9   B4P7M4   B3NN29   A0A2M3Z512   A0A1L8EER1   A0A2P8Z6T4   A0A2M4AEF7   T1PFB1   B4KTT1   Q7Q9C1   A0A182HJJ2   B4MRY0   A0A1I8QAR8   A0A182FPE2   A0A0L0C5I4   B4GGR1   A0A182M072   A0A336KWV3   A0A2P2HWS3   A0A1W4VCJ1   A0A069DMX4   A0A3B0JNX9   A0A023F825   T1DKV1   A0A336M644   A0A2M4C3K4   B3MCS3   B4NSC9   Q7JZK1   A0A0N7Z9G2   R4FPF4   B4HN24   A0A154PEM7   A0A161MLJ2   A0A0A9WBQ8   A0A1J1HMR8   A0A2R7WG33   A0A1B6CPM9   R7VDU5   A0A1Y1M1Y9   A0A1W4WSQ1   A0A226EDV4   A0A1S4E8P0   A0A0P4WG23   A0A1J1J7B6   A0A0N8BP27   A0A0V0G6U0   A0A0P5JZT4  

EC Number

5.2.1.8

Pubmed

28756777    26354079    22118469    23537049    26227816    23622113    + More
22651552    19121390    17994087    25348373    24945155    17510324    26999592    26483478    25244985    15632085    20966253    20920257    23761445    9087549    12364791    14747013    17210077    24495485    17550304    29403074    25315136    26108605    26334808    25474469    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    27129103    25401762    26823975    23254933    28004739   

EMBL

ODYU01005326    SOQ46061.1    KZ149904    PZC78388.1    RSAL01000032    RVE51544.1    + More
KQ461154    KPJ08463.1    AGBW02014484    OWR41601.1    OWR41600.1    APGK01044294    APGK01044295    KB741022    ENN74995.1    JTDY01000051    KOB79166.1    KB631843    ERL86631.1    GDQN01009629    JAT81425.1    GAIX01003559    JAA89001.1    KQ459599    KPI94401.1    AK401687    BAM18309.1    KPJ08462.1    PZC78387.1    BABH01013834    SOQ46060.1    CH940648    EDW60501.1    GDHF01019019    JAI33295.1    GAKP01015138    GAKP01015136    GAKP01015135    JAC43814.1    NEVH01015817    PNF26688.1    CH916375    EDV98128.1    JXJN01025945    GAPW01006061    JAC07537.1    CH477187    GDUN01001025    EAT48887.1    JAN94894.1    JXUM01008769    JXUM01008770    KQ560268    KXJ83442.1    AJWK01015524    AJWK01015525    CP012524    ALC40532.1    CCAG010020733    GFDL01006695    JAV28350.1    CM000071    EAL25513.1    AXCN02000114    ADMH02001538    ETN62135.1    EZ419906    ACZ28261.1    DS232039    EDS32828.1    AAAB01005603    EAA02579.3    GAMC01006524    JAC00032.1    AJVK01009695    GFDF01001803    JAV12281.1    CM000158    EDW90059.1    CH954179    EDV56549.1    GGFM01002858    MBW23609.1    GFDG01001633    JAV17166.1    PYGN01000170    PSN52207.1    GGFK01005829    MBW39150.1    KA647431    AFP62060.1    CH933808    EDW10657.1    AAAB01008904    EAA09633.5    APCN01002170    CH963850    EDW74869.1    JRES01000890    KNC27545.1    CH479183    EDW35681.1    AXCM01015740    UFQS01000611    UFQT01000611    SSX05370.1    SSX25731.1    IACF01000288    LAB66080.1    GBGD01003486    JAC85403.1    OUUW01000001    SPP75036.1    GBBI01001328    JAC17384.1    GAMD01000766    JAB00825.1    SSX05365.1    SSX25726.1    GGFJ01010742    MBW59883.1    CH902619    EDV37325.1    CH982158    CH982159    CM002911    EDX15507.1    EDX15511.1    KMY92889.1    AE013599    AY071209    AAF58729.1    AAL48831.1    AGB93410.1    GDKW01000635    JAI55960.1    ACPB03020118    GAHY01000909    JAA76601.1    CH480816    EDW47328.1    KQ434874    KZC09670.1    GEMB01002303    JAS00878.1    GBHO01038768    GBRD01004963    GDHC01004245    JAG04836.1    JAG60858.1    JAQ14384.1    CVRI01000005    CRK87758.1    KK854775    PTY18603.1    GEDC01026564    GEDC01021862    GEDC01016586    JAS10734.1    JAS15436.1    JAS20712.1    AMQN01004216    AMQN01004217    KB292914    ELU16794.1    GEZM01042665    JAV79743.1    LNIX01000004    OXA55589.1    GDRN01027129    JAI67659.1    CVRI01000074    CRL08279.1    GDIQ01158843    JAK92882.1    GECL01002451    JAP03673.1    GDIQ01196781    JAK54944.1   

Proteomes

UP000283053    UP000053240    UP000007151    UP000019118    UP000037510    UP000030742    + More
UP000053268    UP000005204    UP000008792    UP000235965    UP000001070    UP000092460    UP000075900    UP000008820    UP000092443    UP000078200    UP000069940    UP000249989    UP000092461    UP000092553    UP000075880    UP000075920    UP000092445    UP000092444    UP000076408    UP000075881    UP000091820    UP000001819    UP000075886    UP000075885    UP000075882    UP000076407    UP000000673    UP000075884    UP000002320    UP000007062    UP000092462    UP000075903    UP000002282    UP000008711    UP000245037    UP000095301    UP000009192    UP000075840    UP000007798    UP000095300    UP000069272    UP000037069    UP000008744    UP000075883    UP000192221    UP000268350    UP000007801    UP000000304    UP000000803    UP000015103    UP000001292    UP000076502    UP000183832    UP000014760    UP000192223    UP000198287    UP000079169   

PRIDE

H9J7H0    Q7JZK1   

Pfam

PF05347   Complex1_LYR        + More
PF00335   Tetraspanin
PF11708   Slu7
PF00160   Pro_isomerase

Interpro

IPR016488   NADH_Ub_cplx-1_asu_su-6        + More
IPR008011   Complex1_LYR       
IPR018499   Tetraspanin/Peripherin       
IPR008952   Tetraspanin_EC2_sf       
IPR021715   Slu7_dom       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR020892   Cyclophilin-type_PPIase_CS       
IPR029000   Cyclophilin-like_dom_sf       

SUPFAM

SSF48652   SSF48652        + More
SSF50891   SSF50891       

Gene 3D

1.10.1450.10     2.40.100.10    

ProteinModelPortal

A0A2H1VYZ8   A0A2W1BTJ8   A0A3S2LDS0   A0A194QSG3   A0A212EJF7   A0A212EJF9   + More
N6U0D3   A0A0L7LVH4   U4U7N1   A0A1E1W373   S4P9V1   A0A194PLT7   I4DK69   A0A194QSJ9   A0A2W1BYS3   H9J7H0   A0A2H1VYZ0   B4LJC1   A0A0K8V405   A0A034VMX7   A0A2J7QDN1   B4JVZ0   A0A1B0C5E2   A0A182RJ79   A0A023EDZ8   Q17Q29   A0A1A9YL53   A0A1A9URC8   A0A182GAU6   A0A1B0CJY0   A0A0M4ETG2   A0A182IKX4   A0A182VXQ7   A0A1A9Z2G6   A0A1B0FK01   A0A182XXA2   A0A1Q3FL65   A0A182KFR6   A0A1A9WWU7   Q28ZU9   A0A182QQJ1   A0A182PBG8   A0A182KK73   A0A182XKF2   W5JGV3   A0A182NLA0   D1FQ06   B0WQF7   Q7QM15   W8C2I8   A0A1B0CZR5   A0A1L8E0P9   A0A182UXX9   B4P7M4   B3NN29   A0A2M3Z512   A0A1L8EER1   A0A2P8Z6T4   A0A2M4AEF7   T1PFB1   B4KTT1   Q7Q9C1   A0A182HJJ2   B4MRY0   A0A1I8QAR8   A0A182FPE2   A0A0L0C5I4   B4GGR1   A0A182M072   A0A336KWV3   A0A2P2HWS3   A0A1W4VCJ1   A0A069DMX4   A0A3B0JNX9   A0A023F825   T1DKV1   A0A336M644   A0A2M4C3K4   B3MCS3   B4NSC9   Q7JZK1   A0A0N7Z9G2   R4FPF4   B4HN24   A0A154PEM7   A0A161MLJ2   A0A0A9WBQ8   A0A1J1HMR8   A0A2R7WG33   A0A1B6CPM9   R7VDU5   A0A1Y1M1Y9   A0A1W4WSQ1   A0A226EDV4   A0A1S4E8P0   A0A0P4WG23   A0A1J1J7B6   A0A0N8BP27   A0A0V0G6U0   A0A0P5JZT4  

PDB

5GUP     E-value=6.79652e-14,     Score=181

KEGG

101738818    K03950 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6 | (RefSeq) NADH dehydrogenase [u

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0006979   GO:0005747   GO:0006120   GO:0003954   GO:0005739   GO:0008137   GO:0006457   GO:0003755  

PANTHER

PTHR12964  

Length:

82

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.29855

Exp number, first 60 AAs:

0.29855

Total prob of N-in:

0.26210

outside

1  -  82

 

 

Pi

249.679726

Theta

205.262972

Tajima's D

0.659813

CLR

0

CSRT

0.56347182640868

Interpretation

Uncertain