SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO04529  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA005347
Annotation
ADP-ribosylation_factor_[Bombyx_mori]
Full name
ADP-ribosylation factor 1      
Alternative Name
lARF1
Location in the cell
Mitochondrial   Reliability : 1.077
 

Sequence

CDS
ATGGGGAATATGTTTGCGAATTTATTTAAAGGCCTTTTTGGCAAAAAGGAAATGAGAATATTGATGGTTGGTTTGGATGCAGCTGGTAAAACCACAATTCTGTACAAACTCAAATTAGGTGAAATTGTAACAACAATTCCCACTATTGGCTTTAATGTGGAGACAGTAGAATACAAAAACATTAGTTTTACTGTGTGGGATGTTGGAGGCCAAGACAAAATCAGACCACTGTGGAGGCATTATTTCCAAAATACACAGGGTCTAATCTTCGTAGTAGACAGTAACGATCGGGAACGTATCGGCGAGGCACGCGAAGAGCTCATGAGGATGCTCAGCGAAGATGAACTACGGGATGCAGTACTTTTGATCTTTGCGAATAAACAGGATTTGCCAAACGCAATGAACGCAGCCGAGATAACAGACAAACTGGGTCTGCATTCGCTGCGCAACCGTAACTGGTACATCCAAGCGACATGCGCCACTTCCGGAGACGGACTGTACGAGGGTCTCGACTGGCTCTCCAATCAGCTCAAGAACGCCAACCGCTAA
Protein
MGNMFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIGEAREELMRMLSEDELRDAVLLIFANKQDLPNAMNAAEITDKLGLHSLRNRNWYIQATCATSGDGLYEGLDWLSNQLKNANR

Summary

Description
GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development (PubMed:21976699). Required for cleavage furrow ingression in embryonic cells (PubMed:27535433).
Similarity
Belongs to the small GTPase superfamily. Arf family.
Keywords
ER-Golgi transport   Golgi apparatus   GTP-binding   Lipoprotein   Myristate   Nucleotide-binding   Protein transport   Transport   Complete proteome   Cytoplasm   Reference proteome  
Feature
chain  ADP-ribosylation factor 1
EMBL
JF915770    AET74048.1    KZ149904    PZC78383.1    AK402520    BAM19142.1    + More
KQ461154    KPJ08457.1    GDQN01000515    JAT90539.1    ODYU01002287    SOQ39574.1    GAIX01003443    JAA89117.1    MG846926    AXY94778.1    BABH01013828    DQ311145    ABD36090.1    AK401264    KQ459599    BAM17886.1    KPI94406.1    RSAL01000032    RVE51549.1    UFQT01001374    SSX30252.1    KT984804    KU932396    AMZ00356.1    APA34032.1    GBHO01039205    GBRD01011691    GDHC01007872    JAG04399.1    JAG54133.1    JAQ10757.1    AGBW02014484    OWR41595.1    AK417370    BAN20585.1    JX046920    AFO83996.1    GFDF01003517    JAV10567.1    OUUW01000012    SPP87397.1    GALA01000743    JAA94109.1    GAMD01002226    JAA99364.1    GFDL01001039    JAV34006.1    AE014296    AGB94918.1    CH479188    EDW40305.1    GANO01000968    JAB58903.1    NEVH01021221    PNF19728.1    KK852507    KDR22418.1    AJVK01013552    AJVK01013553    CH964101    EDW79471.1    JRES01000005    KNC34978.1    CH480826    EDW44516.1    CH916366    EDV97299.1    GGFM01006670    MBW27421.1    GGFK01001926    MBW35247.1    GDAI01001243    JAI16360.1    AJWK01014890    CM000363    CM002912    EDX11533.1    KMZ01243.1    AXCM01002821    AXCN02001676    CH933809    EDW18819.1    KRG06378.1    CH954178    EDV52801.1    KQS44443.1    KQS44444.1    CH379069    EAL30885.1    KRT07736.1    KRT07737.1    GAMC01011161    GAMC01011160    JAB95395.1    ADMH02001479    GGFL01004224    ETN62397.1    MBW68402.1    DS231875    EDS41801.1    CH902618    EDV41398.1    KPU79091.1    CCAG010018371    EZ422443    ADD18719.1    DQ440221    CH477418    ABF18254.1    EAT41274.1    ATLV01014310    KE524956    KFB38622.1    CH940647    EDW70008.1    KRF84669.1    AXCP01003861    AAAB01008986    EAA00461.2    CM000159    EDW95569.1    KRK02519.1    KRK02520.1    KRK02521.1    APCN01002444    JXUM01129668    JXUM01129669    KQ567480    KXJ69409.1    U90609    S62079    AY060375    GECU01019950    JAS87756.1    JH432007    GQ483535    ADE42873.1    GL762106    EFZ22216.1    GL888679    EGI58543.1    AAZX01000186    AAZX01000188    AAZX01005723    AAZX01010956    AAZX01011092    AAZX01015773    KZ288191    PBC34469.1    KQ435687    KOX81342.1    KQ981993    KYN31117.1    GBYB01005504    JAG75271.1    GL451420    EFN79316.1    ADTU01027564    KQ759893    OAD62064.1    JR039423    JR039424    AEY58690.1    AEY58691.1    KK107020    QOIP01000006    EZA62585.1    RLU21855.1    GFDG01000960    JAV17839.1    GFTR01003024    JAW13402.1    GDKW01000776    JAI55819.1    GECL01003741    JAP02383.1    GEMB01000320    JAS02800.1    HP429371    ADN29871.1    GBGD01003139    JAC85750.1    ACPB03019847    GAHY01000768    JAA76742.1    GBXI01013075    GBXI01012576    GBXI01008671    JAD01217.1    JAD01716.1    JAD05621.1    QCYY01002331    ROT71202.1   
Pfam
PF00025   Arf
Interpro
IPR027417   P-loop_NTPase        + More
IPR005225   Small_GTP-bd_dom       
IPR006689   Small_GTPase_ARF/SAR       
SUPFAM
SSF52540   SSF52540       
PDB
1RRG     E-value=3.30251e-97,     Score=902

Ontologies

Topology

Subcellular location
Golgi apparatus  
Cytoplasm   Localization to the Golgi is dependent on Asap.   With evidence from 4 publications.
Cytosol   Localization to the Golgi is dependent on Asap.   With evidence from 4 publications.
Length:
182
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.04704
Exp number, first 60 AAs:
0.04444
Total prob of N-in:
0.06579
outside
1  -  182
 
 

Population Genetic Test Statistics

Pi
188.443725
Theta
203.72662
Tajima's D
0.30299
CLR
0.208195
CSRT
0.457677116144193
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
25044914 IGEIGIMAIAVPEK 95.24 1e-08
28556443 DAVLLIFANK 100.00 2e-07
28556443 HYFQNTQGLIFVVDSNDR 100.00 3e-04
26822097 IIMVGIDAAGK 100.00 6e-04
26280517 NFGDFFSGGSCIPGVDKPENNPSGDDVSSIKK 100.00 6e-04
25044914 NISFNDR 100.00 6e-04
27102218 YIIDDDRAIFMFK 100.00 6e-04
28467696 NISFNDR 100.00 6e-04
28556443 NISFTVWDVGGQDK 100.00 6e-04
28556443 NISFTVWDVGGQDK 100.00 6e-04
28556443 NISFTVWDVGGQDK 100.00 6e-04
28556443 LMVGLDAAGK 100.00 6e-04
28556443 NISFTVWDVGGQDK 100.00 6e-04
28556443 NISFTVWDVGGQDK 100.00 6e-04
28556443 DAVLLIFANK 100.00 6e-04
28556443 QDLPNAMNAAEITDK 100.00 6e-04
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