Gene

KWMTBOMO04527

Pre Gene Modal

BGIBMGA005348

Annotation

PREDICTED:_dorsal-ventral_patterning_protein_Sog_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr8(-):9180189-9235487      View in EpiBrowser

Full name

Dorsal-ventral patterning protein Sog      

Alternative Name

Short gastrulation protein

Location in the cell

Extracellular   Reliability : 2.343

CDS

ATGGCAACTTATGAATGCCTATTCGGTAAACAAGCAATGGAGTTGGGCTCTCAGTGGTTCGCGGATCTCGGTCCTCCTTTCGGGATCATGTACTGTATCAAATGTGAGTGTATAGCGGTGCAAAAGAAGCGTCGCGTTGTAGCGAAAGTGCATTGTCGGAACATAAAGAATGAATGCCCGGAACCGACTTGTGAAACGCCCGTGCTACTGCCCGGCCGATGCTGTAAGACATGTCCGGGGGATGTTAACTACCCAGACCTTGTGCAAGAAGATATGCCCGGAGACGTGATCATTGAAGAAGCAGATCACAATATGAAACATTTCGCTTCGTTTTTGACCGGTCGATCTCCGCTTTGCGTGCAGCGCGATGACATGACCGGCGTGCCAGTGGCTCCGGGTGTTGCCGCAGCGAGGTTCACGTTCCGCCGCCGTCACCTTTACTGGTCCGTGTTGCTGAGTCCGTCGATGAAAACGCGGCCGCGGGCCCTCGCCTTCTTAGATCGTCAAGGTCAAGTGCTACTCGAGCAATCCTTGAAGAAGATACCCGGCATACACGCAACTTACGAAGAGAAAACGGATAAGCTATGCGGTGTGTGGCGGCGAGTACCACGCCAGTACAAGACCTTATTACGGGACGGCGATCTACACGTTGCTCTTTTATGGGGAGACGAGACCAGCAACTCCATAGACAGCGCTCTGAGTGGCAGAATCGACAGATACCCAGCGCTGTCATCAGAAATGTTCACATCTTTATTGGAACCCGAGAATCCCCCTACCACCTTCAGCCAGGCAACTTGTCGAGGGTCTAAAGATTTAGATCACGAGGAAGGATGGTGGGGTGGTACCGCTGTAATCACATCGGTCGCCGGCGCAGCTCCGAGCTTGTACATGGCTATAGTTTTCAATGGAATTTTTCCGAAAACAGTGAACACGTCAGACCTTGTCAGAGTTGTTTTAACTTTGCCGGACAAAAATCAGACTATCATTGATCAGGTGCAGAGAGTCGCAAAACCAAATTACGATTTCAATTTGCTCGAAGTATCTACTCCCATATCGGCTGCTGAGTTACGATCTTTAGCGAGGGGACGCCTATTGCTCGGCATTGAATCTGTCGAAAATCCCCAAAGGCGTATTTCGGGAAGTGTGAGACAGAAGGGAACATGTGAACTTTTCCACACACCTTTGGTGGCCGAGAGAACACCGGCTGCGCCATCTCCTGAAGGATTGGCTTTGGTCTACATTGACAAGGAAGGATCTCTCGTCTATGATATACAGATGGAAAACGTAGGTGTTGTTGATCCGAAGATAACTTTGGTAGAAGAACAGGGGAAGAGACATTTGCAGGTTGAGATATTGGATACAAGGGTCGGTGTTCTCGCAAGACCAAGCGCCCGGATCTTCCAACCACTATACGACGAACAACTCGTAGTCCATATTGCAGGGGATGCCGGTCCTCCGATTCTACGAGGGCGTCTTACGTCTCGTCTAATGCCAGATGCGGCTGGTTCAGGTCCGGCTTTGTTACGACGCACGACTCAGGCTCGTGTTCCCAATAACATGGCCGGACTTGCATGGTTGTCCGTCGATTCGCTATGCGGACTGTATTACGAGGCAGCGGTCACGGGTAGTTCTCGTTCACGGTCGACGTGGTGGCTGGAGACGCACGCGGGAGGCGAGGACAACGCCCGCGAGCTCGGCGGCGACGAAGGCTGGGTGTTAGAGCCCAGCGCTGCAGAACTAGTGGCTATCCATATCGGAGCCGCGTTCCTAGAGTTGCGAGCACAGGATAATGTCACGGCGCTACTGCGCACGCGCGCTCCCCAGATAAGCGTGCCAACATCGTGCCTACCCGCAGTACCGGGTCCTATAGACAACGAGTTGAGTCCCAAGTATCCACCTAGTCCTTCTGCAGATCAGCTTTCTGACTACGGGCTATATCGATTGAGTGTTGGATATTGTAAGCAAGGAGAAAAATATTACAAGCTCGGGGAAATTTGGACTGACACTGAGACATGTTCGAAATGCGTGTGCGTGATGGGCACGCCGAAATGTGAGCCGGTCCAGTGCCCGCACGTTAACTGCTTAGTACCAACCATTCTACCGCCGGGACATTGCTGCCCAATTTGTACAAATACTACTTCTGCTGCATGGTCAGAAAATGGTAGTTGCGTTTTAGCTGGACAGAGCTATGCTCCTGGCTCCTCCTGGCACCCGTATCTAGTTCCAGGAGGTTACGACACTTGCGCGATATGCACATGTAATTACATCACGAAGCAGATTCACTGTCCTCGGGTGCAATGTCCTCCTCTGAGATGCAGCGAGAAGGATGCCTTCAGACCTGACAAGAAAGCCTGTTGCAGGGTTTGTCCAGAGAATAAAACTAAGAAATCAGATGAGGAGACACCGAAGGATCAGGGAACGCCCAAGACTGCGGAGGAGATATTAGCTGAAGGAGGCTGTCGATTCCCGGACGGGCCGCTACCCAACGGCAAGGAAGTTCATCCATCCATACATTCTCATGGAGAGCAGAGATGCGTCACGTGTCGGTGCAAGGTACCAGTGCTATCTTACTTAAATCATCCATATTGTTTGATTTTTTAA

Protein

MATYECLFGKQAMELGSQWFADLGPPFGIMYCIKCECIAVQKKRRVVAKVHCRNIKNECPEPTCETPVLLPGRCCKTCPGDVNYPDLVQEDMPGDVIIEEADHNMKHFASFLTGRSPLCVQRDDMTGVPVAPGVAAARFTFRRRHLYWSVLLSPSMKTRPRALAFLDRQGQVLLEQSLKKIPGIHATYEEKTDKLCGVWRRVPRQYKTLLRDGDLHVALLWGDETSNSIDSALSGRIDRYPALSSEMFTSLLEPENPPTTFSQATCRGSKDLDHEEGWWGGTAVITSVAGAAPSLYMAIVFNGIFPKTVNTSDLVRVVLTLPDKNQTIIDQVQRVAKPNYDFNLLEVSTPISAAELRSLARGRLLLGIESVENPQRRISGSVRQKGTCELFHTPLVAERTPAAPSPEGLALVYIDKEGSLVYDIQMENVGVVDPKITLVEEQGKRHLQVEILDTRVGVLARPSARIFQPLYDEQLVVHIAGDAGPPILRGRLTSRLMPDAAGSGPALLRRTTQARVPNNMAGLAWLSVDSLCGLYYEAAVTGSSRSRSTWWLETHAGGEDNARELGGDEGWVLEPSAAELVAIHIGAAFLELRAQDNVTALLRTRAPQISVPTSCLPAVPGPIDNELSPKYPPSPSADQLSDYGLYRLSVGYCKQGEKYYKLGEIWTDTETCSKCVCVMGTPKCEPVQCPHVNCLVPTILPPGHCCPICTNTTSAAWSENGSCVLAGQSYAPGSSWHPYLVPGGYDTCAICTCNYITKQIHCPRVQCPPLRCSEKDAFRPDKKACCRVCPENKTKKSDEETPKDQGTPKTAEEILAEGGCRFPDGPLPNGKEVHPSIHSHGEQRCVTCRCKVPVLSYLNHPYCLIF

Description

Putative negative growth factor. Antagonist of dpp, a protein involved in patterning the dorsal region and in the development of the neuroectoderm; dpp inhibition is enhanced by tsg. Required for establishment of a narrow stripe of peak levels of BMP signaling in the dorsal midline of early embryos, that will give rise to the amnioserosa.
Putative negative growth factor (PubMed:7958919). Antagonist of dpp, a protein involved in patterning the dorsal region and in the development of the neuroectoderm; dpp inhibition is enhanced by tsg (PubMed:7958919). Required for establishment of a narrow stripe of peak levels of BMP signaling in the dorsal midline of early embryos, that will give rise to the amnioserosa (PubMed:11260716).

Subunit

Component of a complex composed of dpp, sog and tsg (PubMed:11260716). Interacts with palmitoyltransferase Hip14 (PubMed:20599894).

Similarity

Belongs to the chordin family.

Keywords

Cell membrane   Complete proteome   Developmental protein   Glycoprotein   Golgi apparatus   Growth factor   Growth regulation   Lipoprotein   Membrane   Palmitate   Reference proteome   Repeat   Secreted   Signal-anchor   Transmembrane   Transmembrane helix  

Feature

chain  Dorsal-ventral patterning protein Sog

Uniprot

H9J756   A0A2A4IZJ6   A0A2W1BZU5   A0A2H1VFL6   A0A3S2P5U9   A0A0L7LUN5   + More
A0A194PN39   A0A1E1WFA1   A0A212EJB8   U5ESB1   A0A336M282   A0A0L0C955   A0A034VKS8   A0A0K8VLW4   Q0IFE4   A0A1I8Q788   A0A1Q3FN78   A0A1Q3FN82   B0WH39   A0A1W4VH05   A0A0A1XC83   B4NEC5   B3NTJ0   T1PFX7   A0A1I8M1B1   Q3KN44   M9PH73   Q24025   A0A3B0JTQ2   W8AF09   B4PWQ1   B4IK93   A0A1L8DP90   B4L5H0   A0A1L8DC27   A0A1A9W8Q0   A0A0M5J340   A0A1J1HT19   B4MAV8   A0A310SUP3   A0A2Z6BDU3   A0A182Y516   A0A3L8DNQ2   A0A151HYM8   A0A158NSG1   A0A182N420   A0A195ESB3   A0A182LTZ7   B4R595   B4GWH3   A0A154NYT9   A0A182QL29   A0A182V3K3   A0A3F2Z213   A0A1I8JT81   A0A182GII5   Q7PS07   A0A3B0K1G6   E2AW27   A0A1Y1M0P1   A0A1W4WSF8   A0A1B0CA27   A0A0N0BL02   B3MZ23   A0A182W4U9   E2BKG5   A0A182J073   B4JN88   F4W5N9   A0A151IE46   A0A1B6KQL2   A0A1B6J6Q5   A0A1B6FDB0   A0A026X3K5   A0A182P189   A0A067RCG0   A0A0L7QXB9   A0A023F000   A0A1B6DB02   D6WZD4   Q0ZEL0   W5JQ71   A0A1B0FI18   A0A088A5B2   A0A1B0AN76   A0A1A9XH69   A0A1A9VRT8   A0A1A9ZID5   E0W0M5   A0A182GEE1   A0A1B0D2U9   A0A182RP77   A0A182TCJ8   A0A2H8TDR4   E9IKL9   J9JR62   A0A1B6DTR6   A0A2A3ERV7  

Pubmed

19121390    28756777    26227816    26354079    22118469    26108605    + More
25348373    17510324    25830018    17994087    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    7958919    11260716    20599894    24495485    17550304    18057021    25244985    30249741    21347285    26483478    12364791    20798317    28004739    21719571    24508170    24845553    25474469    18362917    19820115    17050690    20920257    23761445    20566863    21282665   

EMBL

BABH01013821    BABH01013822    NWSH01004478    PCG65059.1    KZ149904    PZC78380.1    + More
ODYU01002287    SOQ39571.1    RSAL01000320    RVE42561.1    JTDY01000051    KOB79167.1    KQ459599    KPI94408.1    GDQN01005438    JAT85616.1    AGBW02014484    OWR41593.1    GANO01002438    JAB57433.1    UFQT01000107    SSX20078.1    JRES01000749    KNC28780.1    GAKP01015868    JAC43084.1    GDHF01012759    JAI39555.1    CH477351    EAT42881.1    GFDL01005985    JAV29060.1    GFDL01006000    JAV29045.1    DS231932    EDS27490.1    GBXI01011856    GBXI01006224    GBXI01005011    JAD02436.1    JAD08068.1    JAD09281.1    CH964239    EDW82094.2    CH954180    EDV46994.1    KA647045    AFP61674.1    BT023895    ABA81829.1    AE014298    AGB95418.1    U18774    BT053679    OUUW01000003    SPP78860.1    GAMC01019741    GAMC01019740    GAMC01019739    JAB86815.1    CM000162    EDX01797.1    CH480852    EDW51485.1    GFDF01005924    JAV08160.1    CH933811    EDW06429.1    KRG06920.1    GFDF01010082    JAV04002.1    CP012528    ALC48636.1    CVRI01000020    CRK91207.1    CH940655    EDW66367.2    KRF82641.1    KQ759893    OAD62062.1    LC373543    BBD17786.1    QOIP01000006    RLU21852.1    KQ976730    KYM76466.1    ADTU01024888    ADTU01024889    KQ981993    KYN31061.1    AXCM01002317    CM000366    EDX17996.1    CH479194    EDW27057.1    KQ434783    KZC04787.1    AXCN02002435    APCN01005714    APCN01005715    APCN01005716    JXUM01066198    KQ562386    KXJ76016.1    AAAB01008846    EAA06317.5    SPP78861.1    GL443213    EFN62449.1    GEZM01043003    JAV79394.1    AJWK01003177    AJWK01003178    KQ435687    KOX81338.1    CH902632    EDV32867.2    GL448795    EFN83805.1    CH916371    EDV92181.1    GL887655    EGI70536.1    KQ977894    KYM98951.1    GEBQ01026257    JAT13720.1    GECU01012849    JAS94857.1    GECZ01021592    JAS48177.1    KK107020    EZA62586.1    KK852555    KDR21447.1    KQ414705    KOC63255.1    GBBI01003892    JAC14820.1    GEDC01014421    JAS22877.1    KQ971372    EFA10780.2    DQ490059    ABF22614.1    ADMH02000792    ETN65045.1    CCAG010013228    CCAG010013229    CCAG010013230    JXJN01000741    DS235861    EEB19181.1    JXUM01057879    JXUM01057880    KQ561976    KXJ77009.1    AJVK01002860    GFXV01000436    MBW12241.1    GL764021    EFZ18871.1    ABLF02032228    ABLF02032231    ABLF02032235    GEDC01008237    JAS29061.1    KZ288191    PBC34468.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000037510    UP000053268    UP000007151    + More
UP000037069    UP000008820    UP000095300    UP000002320    UP000192221    UP000007798    UP000008711    UP000095301    UP000000803    UP000268350    UP000002282    UP000001292    UP000009192    UP000091820    UP000092553    UP000183832    UP000008792    UP000076408    UP000279307    UP000078540    UP000005205    UP000075884    UP000078541    UP000075883    UP000000304    UP000008744    UP000076502    UP000075886    UP000075903    UP000076407    UP000075840    UP000069940    UP000249989    UP000007062    UP000000311    UP000192223    UP000092461    UP000053105    UP000007801    UP000075920    UP000008237    UP000075880    UP000001070    UP000007755    UP000078542    UP000053097    UP000075885    UP000027135    UP000053825    UP000007266    UP000000673    UP000092444    UP000005203    UP000092460    UP000092443    UP000078200    UP000092445    UP000009046    UP000092462    UP000075900    UP000075901    UP000007819    UP000242457   

PRIDE

H9J756    Q3KN44    Q24025   

Pfam

PF07452   CHRD        + More
PF00093   VWC

Interpro

IPR001007   VWF_dom        + More
IPR010895   CHRD       
IPR016353   Chordin       

ProteinModelPortal

H9J756   A0A2A4IZJ6   A0A2W1BZU5   A0A2H1VFL6   A0A3S2P5U9   A0A0L7LUN5   + More
A0A194PN39   A0A1E1WFA1   A0A212EJB8   U5ESB1   A0A336M282   A0A0L0C955   A0A034VKS8   A0A0K8VLW4   Q0IFE4   A0A1I8Q788   A0A1Q3FN78   A0A1Q3FN82   B0WH39   A0A1W4VH05   A0A0A1XC83   B4NEC5   B3NTJ0   T1PFX7   A0A1I8M1B1   Q3KN44   M9PH73   Q24025   A0A3B0JTQ2   W8AF09   B4PWQ1   B4IK93   A0A1L8DP90   B4L5H0   A0A1L8DC27   A0A1A9W8Q0   A0A0M5J340   A0A1J1HT19   B4MAV8   A0A310SUP3   A0A2Z6BDU3   A0A182Y516   A0A3L8DNQ2   A0A151HYM8   A0A158NSG1   A0A182N420   A0A195ESB3   A0A182LTZ7   B4R595   B4GWH3   A0A154NYT9   A0A182QL29   A0A182V3K3   A0A3F2Z213   A0A1I8JT81   A0A182GII5   Q7PS07   A0A3B0K1G6   E2AW27   A0A1Y1M0P1   A0A1W4WSF8   A0A1B0CA27   A0A0N0BL02   B3MZ23   A0A182W4U9   E2BKG5   A0A182J073   B4JN88   F4W5N9   A0A151IE46   A0A1B6KQL2   A0A1B6J6Q5   A0A1B6FDB0   A0A026X3K5   A0A182P189   A0A067RCG0   A0A0L7QXB9   A0A023F000   A0A1B6DB02   D6WZD4   Q0ZEL0   W5JQ71   A0A1B0FI18   A0A088A5B2   A0A1B0AN76   A0A1A9XH69   A0A1A9VRT8   A0A1A9ZID5   E0W0M5   A0A182GEE1   A0A1B0D2U9   A0A182RP77   A0A182TCJ8   A0A2H8TDR4   E9IKL9   J9JR62   A0A1B6DTR6   A0A2A3ERV7  

PDB

1U5M     E-value=0.000525207,     Score=106

KEGG

101745779    K04657 chordin | (RefSeq) dorsal-ventral patterning protein Sog

PATHWAY

04350    TGF-beta signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0007275   GO:0016021   GO:0035271   GO:0061328   GO:0007313   GO:0005518   GO:0008586   GO:0008083   GO:0005886   GO:0030512   GO:0040008   GO:0005576   GO:0030509   GO:0030510   GO:0007354   GO:0007398   GO:0030511   GO:0007378   GO:0000139   GO:0005515   GO:0035023   GO:0016887   GO:0030870   GO:0006310   GO:0006418   GO:0009058   GO:0016742   GO:0003824  

Subcellular location

Golgi apparatus membrane  
Cell membrane  
Secreted  

Length:

866

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.997070000000001

Exp number, first 60 AAs:

0.1179

Total prob of N-in:

0.03056

outside

1  -  866

 

 

Pi

221.612076

Theta

174.157125

Tajima's D

0.558611

CLR

0.318318

CSRT

0.529973501324934

Interpretation

Uncertain