Gene

KWMTBOMO04526  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005458

Annotation

PREDICTED:_serine--pyruvate_aminotransferase-like_[Amyelois_transitella]

Location

Bomo_Chr8(+):9157538-9172094      View in EpiBrowser

Full name

Serine--pyruvate aminotransferase      

Alternative Name

Alanine--glyoxylate aminotransferase

Location in the cell

Extracellular   Reliability : 0.876

CDS

ATGACCGAAATTAAACTAACTGTTCAAGCTCCCACATTAGTAAATCGAGACTTTGTCAAGCCCACGCTGTGTGGTCCAGGCCCCTGTGACGTCTGGCCCTCAGTTAATGAGGCTCTCACCAAACCAGTTATTTCGCCAATTTGCGATGAACATTTCTACGTACTAGATGACATTCGCGCCGGGTTGAAGTATGTTTTTCAGACAAACTGCGACACAGTTCTCGCCCTCAGTGGATCTGGTCACGGTGGTATGGAGACTGTTATAAATAATTTGGTCGGACCCGGTGAAACTTTGCTGGTAGCCAAGAGGGGCTTTTGGTGTGAGCGTGCTCTTGAAATGGCTAAGAGATACGGAATCAACACTATAACAACGACTGTACCGATGAACGAGACGTTTAGTTTGCAACAGCTAGAAAATGAGCTAAGAAAACACCGTCCAACCGCTTTGTTTATAGTCCACGGCGATTCATCTACTGGAATAGTACAAAACTTGAAAAGTGTGGGCGAATTATGTCAAAGATATGGCACCCTTTTGCTGGTCGATACGGTAGTGTCGCTGGTTGGTGTACCATTCTTTATGGACGATTGGAAAATAGACGCGGTTTATACTTCAACCCAAAAAGCTTTCAGCGGCCCAGCTGGCATCAGTCCTGTAGCTTTCAGTGATCGTGCTCTGAACAAAATCAACAACAGAACTCATCAACCTCCTTTCTATTTTGACGTCAAACTATTGAGCCAACAATGGAATTGTTACGGTAGTACAAGAGTATATCATCACACTCTAAGTTCTCCGCTATTGTGGGCGCTACGGCAATGTCTGCAGGAAGTCATCAAAGAGACTTTACCCAGATCTTGGGCCCGACATGCTGCAACCACTAAACACTTCCTCAAAAGAGTAGAACAGCTCTCCTTAAAGACCTTTGTACCGAAACCGGAGGATCGCTTAATGACCGTCACAACGGTAGTCTTGCCCAAAGGATATGATTATTTACAATTCTCTAAATATATGAGAGAGAAATACAATATCTTAATATTTCCCGGCATCGGTCAAACTGTAGGTAAAACCCTACGTATTGGACTTATGGGTGTCAACTCTACAATACAAGTCGCCGATGCTGTTGCAGACGCTGTGGCAGATTGA

Protein

MTEIKLTVQAPTLVNRDFVKPTLCGPGPCDVWPSVNEALTKPVISPICDEHFYVLDDIRAGLKYVFQTNCDTVLALSGSGHGGMETVINNLVGPGETLLVAKRGFWCERALEMAKRYGINTITTTVPMNETFSLQQLENELRKHRPTALFIVHGDSSTGIVQNLKSVGELCQRYGTLLLVDTVVSLVGVPFFMDDWKIDAVYTSTQKAFSGPAGISPVAFSDRALNKINNRTHQPPFYFDVKLLSQQWNCYGSTRVYHHTLSSPLLWALRQCLQEVIKETLPRSWARHAATTKHFLKRVEQLSLKTFVPKPEDRLMTVTTVVLPKGYDYLQFSKYMREKYNILIFPGIGQTVGKTLRIGLMGVNSTIQVADAVADAVAD

Catalytic Activity

L-serine + pyruvate = 3-hydroxypyruvate + L-alanine
glyoxylate + L-alanine = glycine + pyruvate

Cofactor

pyridoxal 5'-phosphate

Similarity

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

Feature

chain  Serine--pyruvate aminotransferase

Uniprot

H9J7G6   A0A2A4JA13   A0A2W1BTN4   A0A2W1BTI9   A0A2A4J9J0   A0A212F566   + More
A0A3S2N685   A0A2H1VZD4   A0A194PTF0   A0A2H1W814   A0A194QT08   A0A194PNT9   A0A0L7LVG8   D6WZD5   A0A1D2M7D5   A0A2J7QYG5   B4MTD7   U5EHZ8   A0A0M9ABU5   A0A0P4VW80   A0A0P4W285   A0A182NL11   V5IAQ9   B3MZ47   A0A1W4VFD6   Q9W3Z3   C6TP18   B3NXS8   A0A3B0KL32   T1PAB8   B4PYT0   B4R5M1   A0A3Q4MTI7   A0A3Q2WPW6   Q29J54   B4GTB5   A0A3B4GVH1   A0A087SQK2   A0A3P8RB99   A0A3P9BRB1   A0A1S3AAW1   A0A1D2A4H9   B4I0A1   A0A182VNH7   A0A3Q1FE22   A0A3P9H7B2   A0A3P9KGC4   I3KT22   A0A3B4VM22   A0A3Q3QX64   Q3LSM4   A0A1Y1KT54   A0A2A3ERY3   K7IQ85   A0A182H713   Q16FD8   A0A3P8VG94   A0A0M4F8F0   N6USA5   A0A182KX75   H2MYK7   A0A3Q4HB18   A0A182M4C6   Q7QH32   A0A3P9KFX5   B0WZW4   A0A3P9H7C5   A0A182WW14   A0A182R878   A0A1Q3FN94   A0A0L0BXN4   A0A3Q3GT65   A0A034VZ82   A0A0C9QS08   A0A0L7QXH0   B4JKK7   A0A154P0L2   A0A0K8W8D1   A0A0A1XJC1   A0A182FKZ2   A0A3B4WR59   A0A182HJY8   A0A3Q0RHC5   A0A182U6U7   A0A182YLN1   A0A182IPW9   A0A059LSR7   A0A2U9C6U5   A0A3Q1AJZ8   A0A1W4X347   A0A3B3ZUX2   B4L6E9   A0A088A573   A0A3R7NTN3   A0A182P8W5   A0A3Q1JI51   B4M824   A0A2K6EMJ8   Q6DIW8  

EC Number

2.6.1.44
2.6.1.51

Pubmed

19121390    28756777    22118469    26354079    26227816    18362917    + More
19820115    27289101    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25315136    17550304    25186727    15632085    25012212    17554307    16681462    16990263    17510324    28004739    20075255    26483478    24487278    23537049    20966253    12364791    14747013    17210077    26108605    25348373    25830018    25244985    24809511    25463417   

EMBL

BABH01013820    BABH01013821    NWSH01002333    PCG68508.1    KZ149904    PZC78379.1    + More
PZC78378.1    PCG68509.1    AGBW02010228    OWR48881.1    RSAL01000320    RVE42562.1    ODYU01005253    SOQ45922.1    KQ459599    KPI94410.1    ODYU01006802    SOQ48992.1    KQ461154    KPJ08454.1    KPI94409.1    JTDY01000051    KOB79161.1    KQ971372    EFA09724.1    LJIJ01003131    ODM88834.1    NEVH01009090    PNF33614.1    CH963851    EDW75376.1    GANO01002824    JAB57047.1    KQ435687    KOX81337.1    GDRN01109190    JAI57113.1    GDRN01109192    JAI57111.1    GALX01000755    JAB67711.1    CH902632    EDV32891.1    AE014298    BT133279    AAF46168.1    AFC38910.1    BT099504    ACU24744.1    CH954180    EDV47379.1    OUUW01000019    SPP89310.1    KA645721    AFP60350.1    CM000162    EDX01016.1    CM000366    EDX17258.1    CH379063    EAL32448.1    CH479190    EDW25785.1    KL662160    QOKY01000184    KFM28006.1    RMZ53954.1    GDKF01004538    JAT74084.1    CH480819    EDW52932.1    AERX01011518    DQ182329    CH477665    ABA26661.1    EAT37540.1    GEZM01077174    JAV63380.1    KZ288191    PBC34467.1    JXUM01115355    KQ565871    KXJ70586.1    CH478461    EAT32945.1    CP012528    ALC48637.1    APGK01018692    KB740082    ENN81587.1    AXCM01000231    AAAB01008820    EAA05410.3    DS232219    EDS37789.1    GFDL01005975    JAV29070.1    JRES01001179    KNC24756.1    GAKP01012084    JAC46868.1    GBYB01003422    JAG73189.1    KQ414705    KOC63256.1    CH916370    EDW00110.1    KQ434783    KZC04788.1    GDHF01004977    JAI47337.1    GBXI01017238    GBXI01002843    JAC97053.1    JAD11449.1    APCN01002223    AYPS01000026    KDD77074.1    CP026254    AWP11446.1    CH933812    EDW05945.1    QCYY01002941    ROT66404.1    CH940653    EDW62300.1    BC075417    BC089751    AAH75417.1    AAH89751.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000283053    UP000053268    UP000053240    + More
UP000037510    UP000007266    UP000094527    UP000235965    UP000007798    UP000053105    UP000075884    UP000007801    UP000192221    UP000000803    UP000008711    UP000268350    UP000095301    UP000002282    UP000000304    UP000261580    UP000264840    UP000001819    UP000008744    UP000261460    UP000028924    UP000279271    UP000265100    UP000265160    UP000079721    UP000001292    UP000075903    UP000257200    UP000265200    UP000265180    UP000005207    UP000261420    UP000261600    UP000008820    UP000242457    UP000002358    UP000069940    UP000249989    UP000265120    UP000092553    UP000019118    UP000075882    UP000001038    UP000075883    UP000007062    UP000002320    UP000076407    UP000075900    UP000037069    UP000261660    UP000053825    UP000001070    UP000076502    UP000069272    UP000261360    UP000075840    UP000261340    UP000075902    UP000076408    UP000075880    UP000026042    UP000246464    UP000257160    UP000192223    UP000261520    UP000009192    UP000005203    UP000283509    UP000075885    UP000265040    UP000008792    UP000233160   

PRIDE

H9J7G6    Q9W3Z3    C6TP18   

Pfam

PF00266   Aminotran_5

Interpro

IPR015424   PyrdxlP-dep_Trfase        + More
IPR000192   Aminotrans_V_dom       
IPR020578   Aminotrans_V_PyrdxlP_BS       
IPR015421   PyrdxlP-dep_Trfase_major       
IPR015422   PyrdxlP-dep_Trfase_dom1       
IPR024169   SP_NH2Trfase/AEP_transaminase       

SUPFAM

SSF53383   SSF53383       

Gene 3D

3.40.640.10     3.90.1150.10    

ProteinModelPortal

H9J7G6   A0A2A4JA13   A0A2W1BTN4   A0A2W1BTI9   A0A2A4J9J0   A0A212F566   + More
A0A3S2N685   A0A2H1VZD4   A0A194PTF0   A0A2H1W814   A0A194QT08   A0A194PNT9   A0A0L7LVG8   D6WZD5   A0A1D2M7D5   A0A2J7QYG5   B4MTD7   U5EHZ8   A0A0M9ABU5   A0A0P4VW80   A0A0P4W285   A0A182NL11   V5IAQ9   B3MZ47   A0A1W4VFD6   Q9W3Z3   C6TP18   B3NXS8   A0A3B0KL32   T1PAB8   B4PYT0   B4R5M1   A0A3Q4MTI7   A0A3Q2WPW6   Q29J54   B4GTB5   A0A3B4GVH1   A0A087SQK2   A0A3P8RB99   A0A3P9BRB1   A0A1S3AAW1   A0A1D2A4H9   B4I0A1   A0A182VNH7   A0A3Q1FE22   A0A3P9H7B2   A0A3P9KGC4   I3KT22   A0A3B4VM22   A0A3Q3QX64   Q3LSM4   A0A1Y1KT54   A0A2A3ERY3   K7IQ85   A0A182H713   Q16FD8   A0A3P8VG94   A0A0M4F8F0   N6USA5   A0A182KX75   H2MYK7   A0A3Q4HB18   A0A182M4C6   Q7QH32   A0A3P9KFX5   B0WZW4   A0A3P9H7C5   A0A182WW14   A0A182R878   A0A1Q3FN94   A0A0L0BXN4   A0A3Q3GT65   A0A034VZ82   A0A0C9QS08   A0A0L7QXH0   B4JKK7   A0A154P0L2   A0A0K8W8D1   A0A0A1XJC1   A0A182FKZ2   A0A3B4WR59   A0A182HJY8   A0A3Q0RHC5   A0A182U6U7   A0A182YLN1   A0A182IPW9   A0A059LSR7   A0A2U9C6U5   A0A3Q1AJZ8   A0A1W4X347   A0A3B3ZUX2   B4L6E9   A0A088A573   A0A3R7NTN3   A0A182P8W5   A0A3Q1JI51   B4M824   A0A2K6EMJ8   Q6DIW8  

PDB

2HUU     E-value=1.14902e-76,     Score=729

KEGG

101737836    K00830 alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transamina

PATHWAY

00250    Alanine, aspartate and glutamate metabolism - Bombyx mori (domestic silkworm)
00260    Glycine, serine and threonine metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0003824   GO:0008453   GO:0004760   GO:0008483   GO:0019265   GO:0005777   GO:0009436   GO:0016021   GO:0042853   GO:0005782   GO:0030170   GO:0046724   GO:0016597   GO:0005102   GO:0019448   GO:0042803   GO:0007219   GO:0043621   GO:0035023   GO:0005515   GO:0016887   GO:0030870   GO:0006310   GO:0006418   GO:0009058   GO:0016742  

Length:

379

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.574530000000001

Exp number, first 60 AAs:

1e-05

Total prob of N-in:

0.03708

outside

1  -  379

 

 

Pi

197.737272

Theta

176.370234

Tajima's D

-0.881838

CLR

181.20286

CSRT

0.15859207039648

Interpretation

Uncertain