Gene

KWMTBOMO04522

Pre Gene Modal

BGIBMGA005351

Annotation

PREDICTED:_rho_guanine_nucleotide_exchange_factor_10_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr8(-):8678844-8735567      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 1.838

CDS

ATGTACAAAACGCAATGTTATGAAAACACATTAGAAATAGGAAACTTTCCAAACGTGAATAAAACAGTGGGTAATGCTTTCCTAGCGAATGCGGGCCCTGCCTGCACGCATTCCGCAGGGAGCCAAGTGCCGGCAATAAGCATTTTACGAGAAGCGAACGGAGCGGGTGGCGGCGCGGCCGGCGGCGGCCTGCTTGCCATGAACGCCACCCAGGTCCAGTGCGAGCCCCACGACTCCGTGGTTCTCATCAAATATGAACATCGATCGGCGGGTGGCAGTTGGGAGGAGCCCGTGAGCGCGGTGCGTAATGCACCTCTCAGACGCTCACAAAGGCTCAACTCCACGCTGGACTCCAGAAGTACCGGACAGCTGCGCAACACCCTCAGCCGTGCGCGGGAGCTGTGCGAACGATGGCGAAGCGGAGGAATCACTCCGCCCGCGCCCCCTCCCGACGACGAGGGCGGGGGGAGGCTGGCGCGCTGGTTCAGCGTACGCAGGGGATCCACGCACCAGTACGACATGCACTCGCACGAAACCGACAAGATGCCCAAATTACCCGAGCTGGAGGAGGATTTGTTCTCGTGCGGCGGTGAGGTTCGAGGAGGGAGAGTTCCGCCGCCGTCTCTGGGCCCTCCGCCGGACTCGCTGACGCCCGTGCAACTGCGTCGTCGGCACGTCGTCGCTGCTATTATACACAGTGAAAACTCATACGTCGCCACTCTACAGCGACTCGTAAATGACTACAAAAAGCCCCTCGAAGAGAGCAGTCCGGCCATATTGAACGCCAGTAAAATACAAACGTTATTCCACCGTCTACCTGACATCCTACAATGCCACCTACACTTCCGCACCGCTCTGGCCGACTGTGCGCAGACGTGGGACCGCGATGAAAAAATAGGCGAGGTCTTTTTGAGCGCATTCTCGAAGGCCGTGGTGCTGGACGTGTATTCGGATTTCATAAATAACTTCTCAGTCGCCATGGAATTGGCTAAAATGGAGTCGAAAAGGAAATCAGCGCTGGCCGACTTCTTCAAAGTGAAGCAGATTAGTGCTCACGACAGACTCTCGTTCTTCGGACTGATGGTTAAGCCGGTTCAGAGGTTTCCGCAGTTCATCATGTTTTTACAGGATTTATTGAAGCACACGCCCCCCGGGCACGCGGACCGTGTGGCTTTACAAAGAGCTTTGACGAGACTAGAGGCGTTAGCCGAAGCATTAAATGAAAGAAAACGTGACGCTGAAAGAACACAGGCATTCCGCGCCGCCCTGAGGAGGCTGACCCGCGGCGGGGTGGCGGGCGCGGGGGGTGCGGGTGGCGCTACCCGGTTCGGCGCGGCCCGCCTGCTCGCCTCCCGGGCTGACAAACGACATTTACTCAGACAAGACGATCTACTGCAAATGGAATTTAACCAGTCGGGTGGCTTATCTAAGTGCAAGCCCCGTCGACTGCTGTTACTGAACGACCTGGTGGTGTGCGTGTCGGTTGGCGCGGGCGGCGATGACGCGGAACGTCTCGGCCTCAAGTGGGCACATCCGGTGCAGGACGTTGAGGTTTTGGACACGGGCACCTCGCCCACGCTCAGTAGAGTGCTCGCTCAAGGTATGAACCGTAGTGGCAGCCTACGTTCAAACTCTAGCAACGGTCAAATGAGCACGTCAACGGGAGATTCTCTCTGCGGCGAGATGTCCACGTTGATGCACGACTATGAGACCGTTTCGAGGATGGCCGACTTGGCGGCCTCCTTGAAAACTCCCTATCCTGAACTAGCACCGGAAATGTTCAAAACCTTGTTGCAGAGTATACAACAAAGCATACAGAAAAAAGACGATGAGATGGCGTGGGTGGATTCTTGTTGTCTCCAACTCCGAATACGCGGTCGGGAGGAGGCGCTGACGTTCCGCGCCAACGAGCCGGGCGCGCGCCTGGGCTGGGCCACGGCGCTGAGGCTGGCTCAGCTGGCCCAGGCGCCCGCCAACTCTCCCGCCTGGAGGGTGCCCGTCTCTCACGCGCCACCACACAAAATGCCGCTCTTTGTCGATGCCAACAATGTCTACTCTTCCAAAAATCTTACAGAGGTTCGATGCGGTTGTTTCTACACATCGAGCGGTAACAATCGCGGCGCCTCGCTGCGTCGCGCTCGCTCGCTGCTGTGGGTGTGTGCGGGCGGCGCCGCGCTCTCGCACGTCGCGGTCCTCACGCACCGGGCCGCCAAACTCAAGACCCTCGTCACCTTAGATCTGCCGGACACCAAGGTCACTTCGATGGAATTCGCCAAAGGAATACGGCAAGTGACCACGCTGTGCGGCGACACCGTGTGGCTCGGCACCGAAGACAAGAAAATAATAATCTTCTCTGCGGTGGAACCGGAGAAACAGGAGAAACTCGCGGAGGTGCCGACCGTGGCCGCCGTCACGCAGATCCGCTACCACTGCGACGCCATGTTCGTGGGACTCACCAACGGACGCGTGGCCGTCTACAGGCGCAACCACGACGACTCCTGGGCGCTGCAGGAGCCGCTGGCCATCGAGCTCGGCGACAAACCCGTGCACTGTCTGCTGCCCGTGGACGGCATCCTCTACGCCACCTGCGCGCGCCGAGTCTTTGCCATCAACGCTCTTACCGCCGAAATCATGCGCATTCTCGAACTCAAGAGCGACGGAGACCGAACAGTGAAATACTTGGCGCACTCCGGCGTCGGTCTGTGGACCGCGTTCTCTGATTCCACATTCGTCAGCCTATACCACGCGGAGACGTTCGAGCATCTACAAAACATAGACATCGCAGCTGATGTTGCTAAAACTATCGGAGCCAGAGACGGCAGTAAGCCCGCCTACGTTTCCGCGCTGCTCGCCAGCCAGGGCCTCCTGTGGGTCGGCACGACCGCTGGCGTCAGCGTCACCGTCCCTCTTCCTAAATTGGAGGGCCTGCCTCTGGTCGGCGGTCACATTGCCGTCTCATATCACGCTCACGCCGGACCCGTCACGTTTCTATTGTCGTTGTTGCCGGAAACGCGCGACATCGACGTCAATGCAGTTCGACGTAACCTCTCGAACGCACGCGCGCTCGCCGACGTGAACATCGTGCACGAGTTCAAAGAGGAGGACTCTAAAGAAGACTGTGACAAACCGAAACTGGAGCGACGAATCTCGGAGGAAACGAGCCCGTACCGACCGCAGCGCGTGCACTCCGCGGTCGTGCGCCGGAAGAAGCCCGGAGACGTGCGTCTGAGCAAAACTCTGCCGAAGTGCGCCAACTTAAACGCTTGCGACGTGTACGGACTGTTTGGCGATCTCATATTCGTGAAGGACTGCGTCGGTGAGAACGATGTGAGCGGCGGCGGCGGTGAGGCGATCCGACGCAGTGACCCCGAGCTGGCCACCATACCGTTCCGCGTGAGCACGCTGGACCGGCGACTGCGCATGCGCGCCGGGCGGCCGCGCAGCCTCGATCTCTCCAACTGGTCGGTAGACTCGCGCGCCTCCAGTCTGTGTACGTCATCGGGAAGCGAGGAGTCAATGGCCCTGCGCGGCGTCTCGAGGAACAGCTCAGGCGCGTCGGGGGCCGCGAGCCTGGCGCCCGTCGCGGTGTCCACGCCGGAATCGTCCGTCGCGTCGAGCAAGTCGTCGTCGCAGCGGTCGGTGGGCAGCACGGGCAGCGCGGGCGAGACGCGGGGCGGGGGGCGCAGCCTGCGCGGCGCGGACTACGCGGTGGGGGAGAGCGCGGCGCGGCGCTCGGTGCTGACGGTGATGGGCGGCCGCGGGTACGTGGACTGGCGGCAGACGGCGGAGGCGGCCGAGCGCCCCGCGCCCGCCGCCGACCCCAACCCTAAGGACGCGTACCTCGTGCTGTGGGAGATGCGCTTGTGA

Protein

MYKTQCYENTLEIGNFPNVNKTVGNAFLANAGPACTHSAGSQVPAISILREANGAGGGAAGGGLLAMNATQVQCEPHDSVVLIKYEHRSAGGSWEEPVSAVRNAPLRRSQRLNSTLDSRSTGQLRNTLSRARELCERWRSGGITPPAPPPDDEGGGRLARWFSVRRGSTHQYDMHSHETDKMPKLPELEEDLFSCGGEVRGGRVPPPSLGPPPDSLTPVQLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVALQRALTRLEALAEALNERKRDAERTQAFRAALRRLTRGGVAGAGGAGGATRFGAARLLASRADKRHLLRQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGGDDAERLGLKWAHPVQDVEVLDTGTSPTLSRVLAQGMNRSGSLRSNSSNGQMSTSTGDSLCGEMSTLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGREEALTFRANEPGARLGWATALRLAQLAQAPANSPAWRVPVSHAPPHKMPLFVDANNVYSSKNLTEVRCGCFYTSSGNNRGASLRRARSLLWVCAGGAALSHVAVLTHRAAKLKTLVTLDLPDTKVTSMEFAKGIRQVTTLCGDTVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDDSWALQEPLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAVSYHAHAGPVTFLLSLLPETRDIDVNAVRRNLSNARALADVNIVHEFKEEDSKEDCDKPKLERRISEETSPYRPQRVHSAVVRRKKPGDVRLSKTLPKCANLNACDVYGLFGDLIFVKDCVGENDVSGGGGEAIRRSDPELATIPFRVSTLDRRLRMRAGRPRSLDLSNWSVDSRASSLCTSSGSEESMALRGVSRNSSGASGAASLAPVAVSTPESSVASSKSSSQRSVGSTGSAGETRGGGRSLRGADYAVGESAARRSVLTVMGGRGYVDWRQTAEAAERPAPAADPNPKDAYLVLWEMRL

Uniprot

H9J759   A0A194PN44   A0A212ELQ1   A0A2W1BXK0   A0A2H1WJ73   A0A1Y1K266   + More
A0A1W4X222   A0A3L8DNJ1   A0A139WBN8   A0A1W4WSE9   A0A1W4X217   A0A1W4WSE7   A0A1W4X3C4   A0A1W4X366   A0A067RC31   D6WZE0   A0A088A5B5   A0A139WBV7   A0A0L7QXC0   A0A154NYX7   A0A2A3E6E9   A0A158NSF0   A0A0M9ADW9   F4W5N8   A0A195ET50   A0A151WWZ0   A0A151HY17   A0A151IE13   A0A310STU5   A0A026X583   E2AW26   E2BKF9   K7IQ84   A0A0T6BEC2   A0A336JX25   A0A336LI48   A0A336LM44   A0A1L8DLW7   A0A232FFP1   A0A0A1WHQ1   A0A0K8VPK8   A0A3R7MNX1   A0A034VFH2   A0A1I8Q594   A0A0C9REB2   A0A1A9UUU8   A0A1B0AK40   A0A1A9W264   E0VFY5   A0A0P5G834   A0A0P5G7J7   A0A0P6GVR7   A0A0P5G8F2   A0A0P6AQ73   A0A0P5MJY2   A0A0N8E8B4   A0A0P5YAT4   A0A0P5FRW9   A0A0P5J4F2   A0A0P5JSY9   A0A0P5GTA9   A0A0P5J7F6   A0A0N7ZPG6   A0A0P6G5U1   A0A0P5LUW8   A0A0P5UVM2   A0A0P5NJ76   A0A0M3QZQ2   A0A0P5PDD4   A0A0N8ED58   A0A0P6HV32   A0A0P5V2J2   A0A0P5VBP2   B4Q2H3   M9PHU0   B3NWU8   E1JJN5   E9H770   B4R6M8   B4IF18   Q9VX48   M9PEZ9   A0A1W4VVY6   A0A0P5WZM7   A0A1W4VIH6   A0A0P5J0B4   A0A0P6IKR3   A0A0P6CU95   A0A1B0CFE5   B5DLR5   A0A0P5MBU7   A0A2P8YFC7   A0A182HDX1   B0WM74   A0A1B0FCZ8   A0A164XKE7   B3MW25  

Pubmed

19121390    26354079    22118469    28756777    28004739    30249741    + More
18362917    19820115    24845553    21347285    21719571    24508170    20798317    20075255    28648823    25830018    25348373    20566863    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    21292972    26109357    26109356    15632085    29403074    26483478   

EMBL

BABH01013792    KQ459599    KPI94413.1    AGBW02013995    OWR42415.1    KZ149904    + More
PZC78375.1    ODYU01009024    SOQ53119.1    GEZM01099129    JAV53476.1    QOIP01000006    RLU21856.1    KQ971372    KYB25332.1    KK852555    KDR21446.1    EFA10412.2    KYB25331.1    KQ414705    KOC63257.1    KQ434783    KZC04791.1    KZ288364    PBC26852.1    ADTU01024887    KQ435687    KOX81333.1    GL887655    EGI70535.1    KQ981993    KYN31059.1    KQ982669    KYQ52459.1    KQ976730    KYM76467.1    KQ977894    KYM98953.1    KQ759893    OAD62058.1    KK107020    EZA62589.1    GL443213    EFN62448.1    GL448795    EFN83799.1    LJIG01001255    KRT85685.1    UFQS01000015    UFQT01000015    SSW97336.1    SSX17722.1    SSW97338.1    SSX17724.1    SSW97337.1    SSX17723.1    GFDF01006635    JAV07449.1    NNAY01000281    OXU29522.1    GBXI01016384    GBXI01002314    JAC97907.1    JAD11978.1    GDHF01011507    JAI40807.1    QCYY01000884    ROT82100.1    GAKP01017743    JAC41209.1    GBYB01005071    GBYB01014939    JAG74838.1    JAG84706.1    DS235129    EEB12291.1    GDIQ01248169    JAK03556.1    GDIQ01252620    JAJ99104.1    GDIQ01038403    JAN56334.1    GDIQ01249770    JAK01955.1    GDIP01025995    JAM77720.1    GDIQ01154701    JAK97024.1    GDIQ01051956    JAN42781.1    GDIP01074276    JAM29439.1    GDIQ01251268    JAK00457.1    GDIQ01205481    JAK46244.1    GDIQ01195485    JAK56240.1    GDIQ01240069    GDIQ01229722    JAK11656.1    GDIQ01202130    JAK49595.1    GDIP01225409    GDIP01094823    GDIP01081775    JAI97992.1    GDIQ01125865    GDIQ01049745    JAN44992.1    GDIQ01164813    JAK86912.1    GDIP01107624    JAL96090.1    GDIQ01151853    JAK99872.1    CP012528    ALC49813.1    GDIQ01151852    JAK99873.1    GDIQ01038404    JAN56333.1    GDIQ01038402    JAN56335.1    GDIP01105018    JAL98696.1    GDIP01102170    JAM01545.1    CM000162    EDX02614.2    AE014298    AGB95485.1    CH954180    EDV46495.2    ACZ95315.2    GL732600    EFX72325.1    CM000366    EDX18227.1    CH480832    EDW46272.1    AY069788    AAF48732.2    AAL39933.1    AGB95487.1    AHN59843.1    GDIP01079322    JAM24393.1    GDIQ01206886    JAK44839.1    GDIQ01009457    JAN85280.1    GDIQ01088471    JAN06266.1    AJWK01010031    AJWK01010032    CH379063    EDY72467.2    GDIQ01166402    JAK85323.1    PYGN01000641    PSN42960.1    JXUM01130525    JXUM01130526    DS231995    EDS30908.1    CCAG010011289    LRGB01000966    KZS14327.1    CH902625    EDV35170.2   

Proteomes

UP000005204    UP000053268    UP000007151    UP000192223    UP000279307    UP000007266    + More
UP000027135    UP000005203    UP000053825    UP000076502    UP000242457    UP000005205    UP000053105    UP000007755    UP000078541    UP000075809    UP000078540    UP000078542    UP000053097    UP000000311    UP000008237    UP000002358    UP000215335    UP000283509    UP000095300    UP000078200    UP000092445    UP000091820    UP000009046    UP000092553    UP000002282    UP000000803    UP000008711    UP000000305    UP000000304    UP000001292    UP000192221    UP000092461    UP000001819    UP000245037    UP000069940    UP000002320    UP000092444    UP000076858    UP000007801   

PRIDE

H9J759    M9PHU0    E1JJN5    Q9VX48   

Pfam

PF00621   RhoGEF

Interpro

IPR000219   DH-domain        + More
IPR035899   DBL_dom_sf       
IPR039919   ARHGEF10/ARHGEF17       
IPR011047   Quinoprotein_ADH-like_supfam       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001849   PH_domain       
IPR036322   WD40_repeat_dom_sf       
IPR011044   Quino_amine_DH_bsu       

SUPFAM

SSF48065   SSF48065        + More
SSF50998   SSF50998       
SSF50978   SSF50978       
SSF50969   SSF50969       

Gene 3D

1.20.900.10     2.130.10.10    

CDD

cd00160  RhoGEF

ProteinModelPortal

H9J759   A0A194PN44   A0A212ELQ1   A0A2W1BXK0   A0A2H1WJ73   A0A1Y1K266   + More
A0A1W4X222   A0A3L8DNJ1   A0A139WBN8   A0A1W4WSE9   A0A1W4X217   A0A1W4WSE7   A0A1W4X3C4   A0A1W4X366   A0A067RC31   D6WZE0   A0A088A5B5   A0A139WBV7   A0A0L7QXC0   A0A154NYX7   A0A2A3E6E9   A0A158NSF0   A0A0M9ADW9   F4W5N8   A0A195ET50   A0A151WWZ0   A0A151HY17   A0A151IE13   A0A310STU5   A0A026X583   E2AW26   E2BKF9   K7IQ84   A0A0T6BEC2   A0A336JX25   A0A336LI48   A0A336LM44   A0A1L8DLW7   A0A232FFP1   A0A0A1WHQ1   A0A0K8VPK8   A0A3R7MNX1   A0A034VFH2   A0A1I8Q594   A0A0C9REB2   A0A1A9UUU8   A0A1B0AK40   A0A1A9W264   E0VFY5   A0A0P5G834   A0A0P5G7J7   A0A0P6GVR7   A0A0P5G8F2   A0A0P6AQ73   A0A0P5MJY2   A0A0N8E8B4   A0A0P5YAT4   A0A0P5FRW9   A0A0P5J4F2   A0A0P5JSY9   A0A0P5GTA9   A0A0P5J7F6   A0A0N7ZPG6   A0A0P6G5U1   A0A0P5LUW8   A0A0P5UVM2   A0A0P5NJ76   A0A0M3QZQ2   A0A0P5PDD4   A0A0N8ED58   A0A0P6HV32   A0A0P5V2J2   A0A0P5VBP2   B4Q2H3   M9PHU0   B3NWU8   E1JJN5   E9H770   B4R6M8   B4IF18   Q9VX48   M9PEZ9   A0A1W4VVY6   A0A0P5WZM7   A0A1W4VIH6   A0A0P5J0B4   A0A0P6IKR3   A0A0P6CU95   A0A1B0CFE5   B5DLR5   A0A0P5MBU7   A0A2P8YFC7   A0A182HDX1   B0WM74   A0A1B0FCZ8   A0A164XKE7   B3MW25  

PDB

5N7E     E-value=6.92405e-16,     Score=210

KEGG

101745631    K16727 Rho guanine nucleotide exchange factor 10 | (RefSeq) rho guanine nucleotide exchange factor 1

GO

GO:0005089   GO:0035023   GO:0030036   GO:0005085   GO:0051496   GO:0016021   GO:0007480   GO:0035025   GO:0005515   GO:0016887   GO:0030870   GO:0006310   GO:0006418   GO:0009058   GO:0016742   GO:0003824  

PANTHER

PTHR12877  

Length:

1288

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.762589999999997

Exp number, first 60 AAs:

0.06181

Total prob of N-in:

0.01144

outside

1  -  1288

 

 

Pi

201.803713

Theta

168.089437

Tajima's D

0.461042

CLR

0.204443

CSRT

0.507024648767562

Interpretation

Possibly Positive selection