Gene

KWMTBOMO04513  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005452

Annotation

PREDICTED:_ribosome_biogenesis_protein_WDR12_homolog_[Amyelois_transitella]

Location

Bomo_Chr8(+):8349898-8353468      View in EpiBrowser

Full name

Ribosome biogenesis protein WDR12 homolog      

Location in the cell

Extracellular   Reliability : 1.719

CDS

ATGATCACTTACCGTGGCCACGACAAGGGAATTGAATGCCTGTCTGTGTCGGCTGATGGTAACCGTTTTGCAAGTGGGAGCTGGGATAACAATGTTTGTCTTTGGAGTGCAAGCTTAGCAGAAGAAGAAAACCATCCAGCTACGAAGAAAAGTAAACCAGAACACGGCACCACTAGAAATCCACTGACCACTTTAAAAGGACACAAGGAGGCTATCTCGGGTGTTCAATGGATGGATTACAACACAGTACTGTCCAGTGGTTGGGACCACTTATTGAAAATTTGGGACTGTGATTTGGGTGGTATTAAACAAGAAATTGCTGGTAATAAGGCCTTTTTTGATGTTGATTGGTCACCTCTGAACAACAGCATTATTACTGCATCAGCAGATAGACATGTCCGGTTATATGACCCTAGATCTACAGAGAGTATTGTGAAGACAACATTCACATCACACACAGGATGGGTCCAGTCAGTTCGCTGGTCTAAAACAAAAGACACTCTTTTCCTTTCTGCTGGATACGACAACCAGGTTAAACTTTGGGAAACAAGAAGTCCACGAACTCCACTTTATGACCTTAGCGGACACGAAGATAAAGTTCTCTGCTGCGATTGGTCGAATCCCTCCCTGTTAATCAGCGGCTCCAGCGACAACACCCTCAGGATATTCAAAGCTAAACACGCTGTCGGAAACGCGTGA

Protein

MITYRGHDKGIECLSVSADGNRFASGSWDNNVCLWSASLAEEENHPATKKSKPEHGTTRNPLTTLKGHKEAISGVQWMDYNTVLSSGWDHLLKIWDCDLGGIKQEIAGNKAFFDVDWSPLNNSIITASADRHVRLYDPRSTESIVKTTFTSHTGWVQSVRWSKTKDTLFLSAGYDNQVKLWETRSPRTPLYDLSGHEDKVLCCDWSNPSLLISGSSDNTLRIFKAKHAVGNA

Description

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Similarity

Belongs to the WD repeat WDR12/YTM1 family.

Keywords

Complete proteome   Nucleus   Reference proteome   Repeat   Ribosome biogenesis   rRNA processing   WD repeat  

Feature

chain  Ribosome biogenesis protein WDR12 homolog

Uniprot

H9J7G0   A0A1E1WVF7   S4PAA1   A0A2H1VX79   A0A194PTG5   A0A194QSD8   + More
A0A212EU55   A0A0M8ZQ61   A0A154PCV7   A0A0L7QLU0   A0A088APV0   K7IPU9   A0A2A3EIG1   A0A2J7PTS2   A0A2P8ZJU2   A0A067RI71   A0A336M4V3   A0A336MRQ0   A0A0J7KVS6   A0A195CCI8   A0A195BXA9   E2A5I5   A0A158NV27   F4WJF8   A0A182JK61   A0A1L8E5Q2   E9IDJ5   U5EMY7   A0A195FQE1   A0A1B6LNN0   A0A1L8E5J4   A0A232FKL2   A0A1B0D3H9   A0A182MM64   B0W517   A0A1J1IMX4   A0A182JPN2   A0A1S4J4Q8   A0A151WSV7   A0A1B6CDM3   A0A0P5GDL0   A0A084VNZ8   A0A1B6F462   E0W0L8   A0A1Q3G5G0   A0A0P5VES8   T1PJQ0   A0A0P4XXA8   A0A0P4Z3F0   A0A0P5KWT2   W8BY51   A0A182H105   A0A0P5GQ38   E2BUS4   A0A0A1WW16   A0A0P5TAV2   A0A182UCN1   A0A2C9GS25   Q7QJ33   A0A182KQQ1   A0A182YMN0   A0A182VC50   A0A0N8D4Y7   A0A182NKR6   Q17BB0   A0A0P5V3X0   A0A0N8CL69   A0A0P5W3D9   A0A1I8PIR2   A0A0N8CSN7   A0A0P6E3F7   E9GZX3   A0A0P5S6C9   A0A0P5YGU0   A0A0P5RWG4   A0A0P5H6D5   A0A0P5PG41   J9JKF4   A0A2S2PD99   A0A0P5UNK4   A0A0P6JV15   A0A226DZG9   A0A2H8TPF2   A0A0P5YTL3   A0A0P5NHJ9   A0A182QG95   A0A2M4AE07   A0A0P5ACV7   T1EA97   A0A0N8B493   A0A2M4ADT5   A0A2M4ADT1   A0A1D2N9P5   A0A182P250   A0A0K8VFN1   W5J4E0   A0A182XLL4   A0A1W4WZ08   A0A3B0JHC4   A0A0P5CKE9  

Pubmed

19121390    23622113    26354079    22118469    20075255    29403074    + More
24845553    20798317    21347285    21719571    21282665    28648823    24438588    20566863    25315136    24495485    26483478    25830018    12364791    20966253    25244985    17510324    21292972    27289101    20920257    23761445   

EMBL

BABH01013775    GDQN01000044    JAT91010.1    GAIX01003344    JAA89216.1    ODYU01005000    + More
SOQ45440.1    KQ459599    KPI94425.1    KQ461154    KPJ08438.1    AGBW02012491    OWR44991.1    KQ435922    KOX68667.1    KQ434874    KZC09682.1    KQ414905    KOC59618.1    KZ288232    PBC31507.1    NEVH01021221    PNF19730.1    PYGN01000035    PSN56766.1    KK852619    KDR20110.1    UFQS01000560    UFQT01000560    SSX04950.1    SSX25312.1    UFQT01001049    SSX28628.1    LBMM01002784    KMQ94369.1    KQ978023    KYM97941.1    KQ976401    KYM92593.1    GL436989    EFN71297.1    ADTU01026871    ADTU01026872    GL888182    EGI65736.1    GFDF01000242    JAV13842.1    GL762454    EFZ21373.1    GANO01000809    JAB59062.1    KQ981335    KYN42636.1    GEBQ01014699    GEBQ01006134    JAT25278.1    JAT33843.1    GFDF01000195    JAV13889.1    NNAY01000087    OXU31123.1    AJVK01010976    AXCM01002371    DS231840    CVRI01000055    CRL01098.1    KQ982769    KYQ50877.1    GEDC01025918    JAS11380.1    GDIQ01242454    JAK09271.1    ATLV01014965    KE524999    KFB39692.1    GECZ01024791    JAS44978.1    DS235861    EEB19174.1    GFDL01000010    JAV35035.1    GDIP01102803    JAM00912.1    KA648981    AFP63610.1    GDIP01235437    JAI87964.1    GDIP01218541    JAJ04861.1    GDIQ01186312    JAK65413.1    GAMC01002278    JAC04278.1    JXUM01102366    KQ564722    KXJ71840.1    GDIQ01239350    JAK12375.1    GL450746    EFN80547.1    GBXI01011659    JAD02633.1    GDIP01134803    JAL68911.1    APCN01000179    AAAB01008807    GDIP01068351    JAM35364.1    CH477324    GDIP01120896    JAL82818.1    GDIP01120895    JAL82819.1    GDIP01105600    GDIQ01061559    JAL98114.1    JAN33178.1    GDIP01102751    JAM00964.1    GDIP01136042    GDIQ01083103    JAL67672.1    JAN11634.1    GL732579    EFX74983.1    GDIQ01108898    JAL42828.1    GDIP01059610    JAM44105.1    GDIQ01095689    JAL56037.1    GDIQ01231656    JAK20069.1    GDIQ01139034    JAL12692.1    ABLF02004647    ABLF02004648    ABLF02059306    GGMR01014745    MBY27364.1    GDIP01114158    JAL89556.1    GDIQ01007746    JAN86991.1    LNIX01000009    OXA50091.1    GFXV01004252    MBW16057.1    GDIP01054821    JAM48894.1    GDIQ01152630    JAK99095.1    AXCN02000542    GGFK01005621    MBW38942.1    GDIP01204142    JAJ19260.1    GAMD01000622    JAB00969.1    GDIQ01214315    JAK37410.1    GGFK01005622    MBW38943.1    GGFK01005620    MBW38941.1    LJIJ01000132    ODN01974.1    GDHF01014637    JAI37677.1    ADMH02002093    ETN59327.1    OUUW01000006    SPP81747.1    GDIP01170343    JAJ53059.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000053105    UP000076502    + More
UP000053825    UP000005203    UP000002358    UP000242457    UP000235965    UP000245037    UP000027135    UP000036403    UP000078542    UP000078540    UP000000311    UP000005205    UP000007755    UP000075880    UP000078541    UP000215335    UP000092462    UP000075883    UP000002320    UP000183832    UP000075881    UP000075809    UP000030765    UP000009046    UP000095301    UP000069940    UP000249989    UP000008237    UP000075902    UP000075840    UP000007062    UP000075882    UP000076408    UP000075903    UP000075884    UP000008820    UP000095300    UP000000305    UP000007819    UP000198287    UP000075886    UP000094527    UP000075885    UP000000673    UP000076407    UP000192223    UP000268350   

PRIDE

H9J7G0   

Pfam

PF00400   WD40        + More
PF08154   NLE
PF00621   RhoGEF
PF12738   PTCB-BRCT
PF16450   Prot_ATP_ID_OB
PF00004   AAA
PF17862   AAA_lid_3

Interpro

IPR017986   WD40_repeat_dom        + More
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR028599   WDR12/Ytm1       
IPR012972   NLE       
IPR020472   G-protein_beta_WD-40_rep       
IPR019775   WD40_repeat_CS       
IPR000219   DH-domain       
IPR035899   DBL_dom_sf       
IPR001357   BRCT_dom       
IPR026817   Ect2       
IPR001331   GDS_CDC24_CS       
IPR011993   PH-like_dom_sf       
IPR036420   BRCT_dom_sf       
IPR003960   ATPase_AAA_CS       
IPR027417   P-loop_NTPase       
IPR003959   ATPase_AAA_core       
IPR005937   26S_Psome_P45-like       
IPR032501   Prot_ATP_ID_OB       
IPR003593   AAA+_ATPase       
IPR041569   AAA_lid_3       

SUPFAM

SSF50978   SSF50978        + More
SSF48065   SSF48065       
SSF52113   SSF52113       
SSF52540   SSF52540       

Gene 3D

2.130.10.10     1.20.900.10     2.30.29.30     3.40.50.10190    

CDD

cd00027  BRCT
cd00160  RhoGEF

ProteinModelPortal

H9J7G0   A0A1E1WVF7   S4PAA1   A0A2H1VX79   A0A194PTG5   A0A194QSD8   + More
A0A212EU55   A0A0M8ZQ61   A0A154PCV7   A0A0L7QLU0   A0A088APV0   K7IPU9   A0A2A3EIG1   A0A2J7PTS2   A0A2P8ZJU2   A0A067RI71   A0A336M4V3   A0A336MRQ0   A0A0J7KVS6   A0A195CCI8   A0A195BXA9   E2A5I5   A0A158NV27   F4WJF8   A0A182JK61   A0A1L8E5Q2   E9IDJ5   U5EMY7   A0A195FQE1   A0A1B6LNN0   A0A1L8E5J4   A0A232FKL2   A0A1B0D3H9   A0A182MM64   B0W517   A0A1J1IMX4   A0A182JPN2   A0A1S4J4Q8   A0A151WSV7   A0A1B6CDM3   A0A0P5GDL0   A0A084VNZ8   A0A1B6F462   E0W0L8   A0A1Q3G5G0   A0A0P5VES8   T1PJQ0   A0A0P4XXA8   A0A0P4Z3F0   A0A0P5KWT2   W8BY51   A0A182H105   A0A0P5GQ38   E2BUS4   A0A0A1WW16   A0A0P5TAV2   A0A182UCN1   A0A2C9GS25   Q7QJ33   A0A182KQQ1   A0A182YMN0   A0A182VC50   A0A0N8D4Y7   A0A182NKR6   Q17BB0   A0A0P5V3X0   A0A0N8CL69   A0A0P5W3D9   A0A1I8PIR2   A0A0N8CSN7   A0A0P6E3F7   E9GZX3   A0A0P5S6C9   A0A0P5YGU0   A0A0P5RWG4   A0A0P5H6D5   A0A0P5PG41   J9JKF4   A0A2S2PD99   A0A0P5UNK4   A0A0P6JV15   A0A226DZG9   A0A2H8TPF2   A0A0P5YTL3   A0A0P5NHJ9   A0A182QG95   A0A2M4AE07   A0A0P5ACV7   T1EA97   A0A0N8B493   A0A2M4ADT5   A0A2M4ADT1   A0A1D2N9P5   A0A182P250   A0A0K8VFN1   W5J4E0   A0A182XLL4   A0A1W4WZ08   A0A3B0JHC4   A0A0P5CKE9  

PDB

6N31     E-value=1.61936e-50,     Score=501

KEGG

101736588    K14863 ribosome biogenesis protein | (RefSeq) ribosome biogenesis protein WDR12 homolog

GO

GO:0000466   GO:0005654   GO:0000463   GO:0043021   GO:0005730   GO:0030687   GO:0042254   GO:0006364   GO:0005089   GO:0035556   GO:2000431   GO:0005096   GO:0035023   GO:0005737   GO:0070545   GO:0036402   GO:0030163   GO:0005524   GO:0005515   GO:0046872   GO:0006281   GO:0016887   GO:0030870   GO:0006310   GO:0006418   GO:0009058   GO:0016742   GO:0003824  

PANTHER

PTHR16777  

Subcellular location

Nucleus  
Nucleolus  
Nucleoplasm  
  

Length:

232

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00013

Exp number, first 60 AAs:

0

Total prob of N-in:

0.15003

outside

1  -  232

 

 

Pi

229.030651

Theta

199.29392

Tajima's D

0.466309

CLR

0.033259

CSRT

0.498525073746313

Interpretation

Uncertain