Gene

KWMTBOMO04512  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005452

Annotation

PREDICTED:_ribosome_biogenesis_protein_WDR12_homolog_[Amyelois_transitella]

Location

Bomo_Chr8(+):8347868-8348853      View in EpiBrowser

Full name

Ribosome biogenesis protein WDR12 homolog      

Location in the cell

Extracellular   Reliability : 2.076

CDS

ATGTCTGGCGATGCTTTAGAAGCTCAATTGCAAGTTAGATTTATAACTAAACAAGAACAATATGCAGTTCCGGATAGTCCTTACGCTATCCAGTGTAACGTACACCCTGCGGACCTTAATACCTTAATCAACGCAATTTTGAAGGAGACCTCACCATCGTTCGAGAAGGCGGTAATATTTGATTTCTTAGTATGTGGAGAGTTACTTTGTGCCTCCCTCGCAGAGCACTTACAAGAAAAAGGGGTATCGACAGAGGACACGCTTGAGGTCGAATACTTGGAAAGGTTCCCTGCACCAACTCCACAGGACTGTTTAATGCACGATGATTGGGTGTCAGCTGTTCAGGCACACAGTAGTTGGATTCTATCAGGAAGTTATGACAATAGCTTACATATATGGAGCACAAAAGGACAACACAAACTAGCCATACCAGGTCATACATCACCAGTAAAAGCAGTATCATGGGTGTCCTTCCAGGGTGATCAAGCTACATTTGTTAGATATAGCATAGCAGTTATGATCTGA

Protein

MSGDALEAQLQVRFITKQEQYAVPDSPYAIQCNVHPADLNTLINAILKETSPSFEKAVIFDFLVCGELLCASLAEHLQEKGVSTEDTLEVEYLERFPAPTPQDCLMHDDWVSAVQAHSSWILSGSYDNSLHIWSTKGQHKLAIPGHTSPVKAVSWVSFQGDQATFVRYSIAVMI

Description

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.

Similarity

Belongs to the WD repeat WDR12/YTM1 family.
Belongs to the ubiquitin-conjugating enzyme family.

Keywords

Complete proteome   Nucleus   Reference proteome   Repeat   Ribosome biogenesis   rRNA processing   WD repeat  

Feature

chain  Ribosome biogenesis protein WDR12 homolog

Uniprot

H9J7G0   A0A2A4IU73   A0A2H1VX79   A0A1E1WVF7   I4DPL0   A0A194PTG5   + More
S4PAA1   A0A194QSD8   A0A212EU55   A0A1B6J785   A0A1B6LGL4   A0A1B6F462   A0A182MM64   A0A1B6CDM3   A0A0J7KVS6   A0A182YMN0   K7IPU9   A0A182P250   A0A182UCN1   A0A2C9GS25   Q7QJ33   A0A182VC50   A0A1L8E5J4   A0A023ERD6   A0A0M8ZQ61   A0A182KQQ1   E9IDJ5   A0A154PCV7   Q17BB0   A0A088APV0   A0A1Q3G5G0   Q29KQ0   A0A182NKR6   B4GT01   F4WJF8   A0A3B0JHC4   B4KKN1   W5J4E0   A0A195BXA9   W8BY51   A0A182QG95   A0A182XLL4   A0A1B0D3H9   A0A195FQE1   A0A151WSV7   A0A158NV27   A0A2M4ADT5   A0A2P8ZJU2   A0A1I8PIR2   A0A2A3EIG1   B0W517   A0A2M4ADT1   A0A2M4AE07   A0A182JK61   B4HWV6   B4MU54   A0A182JPN2   A0A232FKL2   U5EMY7   A0A195CCI8   A0A2M4BNU7   A0A1W4VSY1   A0A0J9TKT5   B4Q9T6   A0A182F4J1   A0A1A9WZX7   A0A2J7PTS2   Q9VKQ3   M9PB96   A0A0M4EPV5   B4LS78   A0A1A9UMI4   A0A170YP47   A0A1A9XZJ1   A0A1B0B919   B3MJV8   A0A1A9Z7S1   D3TPJ6   A0A1B0G5Y7   T1PJQ0   A0A182R3H8   B4P116   B3N534   A0A0A1WW16   A0A336M4V3   A0A336MRQ0   E0W0L8   B4JPT9   A0A0L0BZH2   A0A0K8VFN1   E9GZX3   A0A182WJQ3   A0A0T6B3S7   T1I4N8   T1EA97   A0A0V0G7F4   A0A034WWZ6   A0A2S2PD99   A0A069DUD1   A0A0L7QLU0  

Pubmed

19121390    22651552    26354079    23622113    22118469    25244985    + More
20075255    12364791    24945155    20966253    21282665    17510324    15632085    17994087    21719571    20920257    23761445    24495485    21347285    29403074    28648823    22936249    10731132    12537572    12537569    12537568    12537573    12537574    16110336    17569856    17569867    20353571    25315136    14525923    25830018    20566863    26108605    21292972    25348373    26334808   

EMBL

BABH01013775    NWSH01007981    PCG62732.1    ODYU01005000    SOQ45440.1    GDQN01000044    + More
JAT91010.1    AK403658    BAM19850.1    KQ459599    KPI94425.1    GAIX01003344    JAA89216.1    KQ461154    KPJ08438.1    AGBW02012491    OWR44991.1    GECU01012682    JAS95024.1    GEBQ01017142    JAT22835.1    GECZ01024791    JAS44978.1    AXCM01002371    GEDC01025918    JAS11380.1    LBMM01002784    KMQ94369.1    APCN01000179    AAAB01008807    GFDF01000195    JAV13889.1    GAPW01002369    JAC11229.1    KQ435922    KOX68667.1    GL762454    EFZ21373.1    KQ434874    KZC09682.1    CH477324    GFDL01000010    JAV35035.1    CH379061    CH479189    GL888182    EGI65736.1    OUUW01000006    SPP81747.1    CH933807    ADMH02002093    ETN59327.1    KQ976401    KYM92593.1    GAMC01002278    JAC04278.1    AXCN02000542    AJVK01010976    KQ981335    KYN42636.1    KQ982769    KYQ50877.1    ADTU01026871    ADTU01026872    GGFK01005622    MBW38943.1    PYGN01000035    PSN56766.1    KZ288232    PBC31507.1    DS231840    GGFK01005620    MBW38941.1    GGFK01005621    MBW38942.1    CH480818    CH963852    NNAY01000087    OXU31123.1    GANO01000809    JAB59062.1    KQ978023    KYM97941.1    GGFJ01005502    MBW54643.1    CM002910    KMY89620.1    CM000361    NEVH01021221    PNF19730.1    AE014134    AY118871    AGB92898.1    CP012523    ALC38682.1    CH940649    GEMB01003104    JAS00105.1    JXJN01010184    JXJN01010185    CH902620    EZ423348    ADD19624.1    CCAG010022414    KA648981    AFP63610.1    CM000157    AY231921    CH954177    GBXI01011659    JAD02633.1    UFQS01000560    UFQT01000560    SSX04950.1    SSX25312.1    UFQT01001049    SSX28628.1    DS235861    EEB19174.1    CH916372    JRES01001119    KNC25413.1    GDHF01014637    JAI37677.1    GL732579    EFX74983.1    LJIG01015976    KRT81986.1    ACPB03009352    GAMD01000622    JAB00969.1    GECL01002206    JAP03918.1    GAKP01000242    JAC58710.1    GGMR01014745    MBY27364.1    GBGD01001508    JAC87381.1    KQ414905    KOC59618.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000075883    + More
UP000036403    UP000076408    UP000002358    UP000075885    UP000075902    UP000075840    UP000007062    UP000075903    UP000053105    UP000075882    UP000076502    UP000008820    UP000005203    UP000001819    UP000075884    UP000008744    UP000007755    UP000268350    UP000009192    UP000000673    UP000078540    UP000075886    UP000076407    UP000092462    UP000078541    UP000075809    UP000005205    UP000245037    UP000095300    UP000242457    UP000002320    UP000075880    UP000001292    UP000007798    UP000075881    UP000215335    UP000078542    UP000192221    UP000000304    UP000069272    UP000091820    UP000235965    UP000000803    UP000092553    UP000008792    UP000078200    UP000092443    UP000092460    UP000007801    UP000092445    UP000092444    UP000095301    UP000075900    UP000002282    UP000008711    UP000009046    UP000001070    UP000037069    UP000000305    UP000075920    UP000015103    UP000053825   

PRIDE

H9J7G0    Q29KQ0    B4GT01    Q9VKQ3    M9PB96    B4LS78    + More
B3MJV8    B4JPT9   

Pfam

PF00400   WD40        + More
PF08154   NLE
PF16450   Prot_ATP_ID_OB
PF00004   AAA
PF17862   AAA_lid_3
PF00621   RhoGEF
PF12738   PTCB-BRCT
PF00179   UQ_con
PF13869   NUDIX_2
PF13864   Enkurin
PF01423   LSM

Interpro

IPR017986   WD40_repeat_dom        + More
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR028599   WDR12/Ytm1       
IPR012972   NLE       
IPR020472   G-protein_beta_WD-40_rep       
IPR019775   WD40_repeat_CS       
IPR003960   ATPase_AAA_CS       
IPR027417   P-loop_NTPase       
IPR003959   ATPase_AAA_core       
IPR005937   26S_Psome_P45-like       
IPR032501   Prot_ATP_ID_OB       
IPR003593   AAA+_ATPase       
IPR041569   AAA_lid_3       
IPR000219   DH-domain       
IPR035899   DBL_dom_sf       
IPR001357   BRCT_dom       
IPR026817   Ect2       
IPR001331   GDS_CDC24_CS       
IPR011993   PH-like_dom_sf       
IPR036420   BRCT_dom_sf       
IPR016135   UBQ-conjugating_enzyme/RWD       
IPR000608   UBQ-conjugat_E2       
IPR023313   UBQ-conjugating_AS       
IPR027012   Enkurin_dom       
IPR016706   Cleav_polyA_spec_factor_su5       
IPR000086   NUDIX_hydrolase_dom       
IPR001163   LSM_dom_euk/arc       
IPR010920   LSM_dom_sf       
IPR034102   Sm_D1       

SUPFAM

SSF50978   SSF50978        + More
SSF52540   SSF52540       
SSF48065   SSF48065       
SSF52113   SSF52113       
SSF54495   SSF54495       
SSF50182   SSF50182       

Gene 3D

2.130.10.10     1.20.900.10     2.30.29.30     3.40.50.10190     3.10.110.10    

CDD

cd00027  BRCT
cd00160  RhoGEF
cd00195  UBCc
cd01724  Sm_D1

ProteinModelPortal

H9J7G0   A0A2A4IU73   A0A2H1VX79   A0A1E1WVF7   I4DPL0   A0A194PTG5   + More
S4PAA1   A0A194QSD8   A0A212EU55   A0A1B6J785   A0A1B6LGL4   A0A1B6F462   A0A182MM64   A0A1B6CDM3   A0A0J7KVS6   A0A182YMN0   K7IPU9   A0A182P250   A0A182UCN1   A0A2C9GS25   Q7QJ33   A0A182VC50   A0A1L8E5J4   A0A023ERD6   A0A0M8ZQ61   A0A182KQQ1   E9IDJ5   A0A154PCV7   Q17BB0   A0A088APV0   A0A1Q3G5G0   Q29KQ0   A0A182NKR6   B4GT01   F4WJF8   A0A3B0JHC4   B4KKN1   W5J4E0   A0A195BXA9   W8BY51   A0A182QG95   A0A182XLL4   A0A1B0D3H9   A0A195FQE1   A0A151WSV7   A0A158NV27   A0A2M4ADT5   A0A2P8ZJU2   A0A1I8PIR2   A0A2A3EIG1   B0W517   A0A2M4ADT1   A0A2M4AE07   A0A182JK61   B4HWV6   B4MU54   A0A182JPN2   A0A232FKL2   U5EMY7   A0A195CCI8   A0A2M4BNU7   A0A1W4VSY1   A0A0J9TKT5   B4Q9T6   A0A182F4J1   A0A1A9WZX7   A0A2J7PTS2   Q9VKQ3   M9PB96   A0A0M4EPV5   B4LS78   A0A1A9UMI4   A0A170YP47   A0A1A9XZJ1   A0A1B0B919   B3MJV8   A0A1A9Z7S1   D3TPJ6   A0A1B0G5Y7   T1PJQ0   A0A182R3H8   B4P116   B3N534   A0A0A1WW16   A0A336M4V3   A0A336MRQ0   E0W0L8   B4JPT9   A0A0L0BZH2   A0A0K8VFN1   E9GZX3   A0A182WJQ3   A0A0T6B3S7   T1I4N8   T1EA97   A0A0V0G7F4   A0A034WWZ6   A0A2S2PD99   A0A069DUD1   A0A0L7QLU0  

PDB

6EM5     E-value=4.95133e-19,     Score=227

KEGG

101736588    K14863 ribosome biogenesis protein | (RefSeq) ribosome biogenesis protein WDR12 homolog

GO

GO:0000466   GO:0005654   GO:0000463   GO:0043021   GO:0005730   GO:0030687   GO:0042254   GO:0070545   GO:0006364   GO:0036402   GO:0030163   GO:0005737   GO:0005524   GO:0005089   GO:0035556   GO:2000431   GO:0005096   GO:0035023   GO:0016740   GO:0005886   GO:0005829   GO:0006378   GO:0005849   GO:0003729   GO:0000387   GO:0005515   GO:0046872   GO:0006281   GO:0016887   GO:0030870   GO:0006310   GO:0006418   GO:0009058   GO:0016742   GO:0003824  

PANTHER

PTHR16777  

Subcellular location

Nucleus  
Nucleolus  
Nucleoplasm  
  

Length:

174

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0117

Exp number, first 60 AAs:

0.00225

Total prob of N-in:

0.04566

outside

1  -  174

 

 

Pi

133.379087

Theta

153.763935

Tajima's D

-0.414934

CLR

0.427638

CSRT

0.266736663166842

Interpretation

Uncertain