Gene

KWMTBOMO04487

Pre Gene Modal

BGIBMGA005442

Annotation

UDP-glycosyltransferase_UGT39C1_precursor_[Bombyx_mori]

Location

Bomo_Chr8(+):7604583-7606310      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

PlasmaMembrane   Reliability : 2.103

CDS

ATGTGGCAACTAGAAATCCTTTACAATTGGCTACAGGAACTAGTAGAAAAATACGTTCCAAATTTGCCTCAGCCATCTCCGAGCCTTTATGAACTACAGCAGAATGTTTCTTTGTATCTTATGAACACACATTTTAGTTTCGATCCTCCTGCTGCTTATTTGCCCAATTTTATTGAAATCGGCGGTATTCATCTGAATGAAGAAGTCGAAAAACTACCACAAGACATCCAAAGAATATTAGACGAAGCAAGCAATGGAGTTGTGTATGTAAATTTTGGATCTAATATTAAGAGTTCAGAATTGCCTATTGAAAAGAAGAATGCGCTAATCAACGTATTTAAGAGCTTAAACCAAACGGTGCTATGGAAATGGGAAGACGACAATTTTGGCAACCAAACTGCTAACATTAAGACGCGAAAATGGCTGCCACAAAACGAAATCTTAGCTCACCAAAATGTGAGAATATTTATATCACACGGTGGTTTAATGGGAACCATTGAAGCAATTTTCCACGGAGTTCCCATTATTGGCATTCCATTGTTCGGAGATCAATACAATAACCTACTACAAGTAGAAAATGCAGGATCTGGTATCATTCTTGAATATCACAACTTAAATGAAAACAATATGCGTTCTCTGATAAACCATGTTCTCAGTGATGAAAAGTACAAAAATAATGCTAGAGAACTATCGATAAGGTTTAGAGATAGACCAATTAAGGCTCTAGACGCTGCAATGTATTGGATCGAATACGTTATAAGACACAAAGGCGCTCATTTCATGAAAAATCCCGCATTAAAATTGAATTGGTTTGCCTACAACATGTATGATGTTTATCTTTTCATTTTATGTGTACTTATAATTAGCGTGTACGTAAGTTATAGATGTTTAAAGGTTTTAGTTTATTTTCGTATAAATACAAAGTTCGATAGAAAATTGTGTGGGAAAGTTAAATTTCAATAA

Protein

MWQLEILYNWLQELVEKYVPNLPQPSPSLYELQQNVSLYLMNTHFSFDPPAAYLPNFIEIGGIHLNEEVEKLPQDIQRILDEASNGVVYVNFGSNIKSSELPIEKKNALINVFKSLNQTVLWKWEDDNFGNQTANIKTRKWLPQNEILAHQNVRIFISHGGLMGTIEAIFHGVPIIGIPLFGDQYNNLLQVENAGSGIILEYHNLNENNMRSLINHVLSDEKYKNNARELSIRFRDRPIKALDAAMYWIEYVIRHKGAHFMKNPALKLNWFAYNMYDVYLFILCVLIISVYVSYRCLKVLVYFRINTKFDRKLCGKVKFQ

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.
Belongs to the ubiquitin-conjugating enzyme family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPT9   H9J7F0   A0A2H1W5A1   A0A191T1L9   H9J7F1   G9LPT8   + More
A0A2A4K0B3   A0A3S2N8S7   G9LPP9   A0A194QSA9   A0A2H4WB64   A0A212FL56   A0A1L8D6G2   A0A194PNY6   D2JLL0   A0A212EHV3   A0A2H4WB65   A0A182M8S5   A0A182R334   A0A182TC71   A0A182NJM1   A0A182Y289   A0A2M4BJX2   A0A2M4BJY0   A0A2M4BJY3   A0A182FDS8   A0A182I6Z1   A0A182JUT3   A0A182L3C8   A0A182VHN2   Q7PTF6   A0A182PQN3   A0A182WWQ5   A0A182WL35   A0A2M3Z343   A0A336K257   A0A182IJQ8   A0A2M3Z3U6   W5JEF5   A0A182QE42   A0A084WK54   A0A2M4AGW6   A0A2M4AFV3   A0A1B0DAR4   A0A2M4AGI4   A0A182TJ21   V5GU86   A0A1Q3FZT2   Q17GE2   A0A182GSW1   A0A1I8Q3X2   A0A182G7B7   A0A1B0CEV9   V5GQB1   A0A1Q3FRS4   A0A1Q3FZT9   Q17GE3   A0A2J7R4T0   B0W9Y5   A0A182SPP8   A0A1S4FQK6   V5I8H8   Q16T56   A0A2J7R4W5   A0A1Q3FR21   A0A1Y1MYW5   A0A182SBM5   Q16T58   A0A182G119   Q17KZ7   A0A182G120   A0A1B0DAR3   A0A336LRS6   L7WMY4   A0A1Y1NF76   A0A1Y9HEP2   A0A023EW79   A0A1S4EZ13   A0A1Y1MYZ1   Q1HRH8   A0A2M4CMN6   B4LYF5   T1PD10   A0A1Y1LHF3   A0A182IIM5   A0A182GYX7   A0A1Q3FQK2   A0A182Y290   A0A1W7R8H2   A0A1S4GSA2   A0A2J7R4W2   A0A2Z4LZD7   A0A1B0DAR5   A0A182FDS7   A0A182RHS4   A0A1L8E195   Q7Q5T0   W5JWX5   A0A2J7Q382   A0A1I8P2N0  

EC Number

2.4.1.17

Pubmed

22155036    19121390    26354079    29027758    22118469    19954531    + More
25244985    20966253    12364791    14747013    17210077    20920257    23761445    24438588    17510324    26483478    28004739    23326229    24945155    17204158    17994087   

EMBL

JQ070246    AEW43162.1    BABH01013714    ODYU01006427    SOQ48259.1    KU680293    + More
ANI21999.1    JQ070245    AEW43161.1    NWSH01000322    PCG77489.1    RSAL01000196    RVE44553.1    JQ070206    AEW43122.1    KQ461154    KPJ08408.1    KY202931    AUC64275.1    AGBW02007908    OWR54430.1    GEYN01000086    JAV02043.1    KQ459599    KPI94459.1    GQ915326    ACZ97420.2    AGBW02014796    OWR41057.1    KY202935    AUC64279.1    AXCM01005982    GGFJ01004214    MBW53355.1    GGFJ01004173    MBW53314.1    GGFJ01004216    MBW53357.1    APCN01003712    AAAB01008807    EAA03993.4    GGFM01002198    MBW22949.1    UFQS01000048    UFQT01000048    SSW98571.1    SSX18957.1    GGFM01002441    MBW23192.1    ADMH02001746    ETN61209.1    AXCN02000438    ATLV01024094    KE525349    KFB50598.1    GGFK01006656    MBW39977.1    GGFK01006354    MBW39675.1    AJVK01013380    GGFK01006565    MBW39886.1    GALX01004658    JAB63808.1    GFDL01001981    JAV33064.1    CH477262    EAT45644.1    JXUM01017315    KQ560480    KXJ82204.1    JXUM01046260    KQ561468    KXJ78484.1    AJWK01009317    AJWK01009318    GALX01004659    JAB63807.1    GFDL01004778    JAV30267.1    GFDL01001967    JAV33078.1    EAT45643.1    NEVH01007402    PNF35837.1    DS231867    EDS40643.1    GALX01004660    JAB63806.1    CH477659    EAT37651.1    PNF35871.1    GFDL01005087    JAV29958.1    GEZM01017163    JAV90862.1    EAT37649.1    JXUM01038022    KQ561151    KXJ79545.1    CH477220    EAT47358.1    JXUM01038023    KXJ79546.1    AJVK01013379    UFQT01000126    SSX20505.1    KC118981    AGC84403.1    GEZM01007277    JAV95265.1    GAPW01000969    JAC12629.1    GEZM01017166    JAV90859.1    DQ440116    ABF18149.1    GGFL01002422    MBW66600.1    CH940650    EDW66951.1    KA645990    AFP60619.1    GEZM01055230    JAV73082.1    APCN01000032    JXUM01021599    KQ560606    KXJ81644.1    GFDL01005243    JAV29802.1    GEHC01000199    JAV47446.1    AAAB01008960    PNF35872.1    MF787212    AWX49640.1    AJVK01013381    GFDF01001625    JAV12459.1    EAA11593.4    ADMH02000091    ETN67850.1    NEVH01019069    PNF23045.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000007151    UP000053268    + More
UP000075883    UP000075900    UP000075901    UP000075884    UP000076408    UP000069272    UP000075840    UP000075881    UP000075882    UP000075903    UP000007062    UP000075885    UP000076407    UP000075920    UP000075880    UP000000673    UP000075886    UP000030765    UP000092462    UP000075902    UP000008820    UP000069940    UP000249989    UP000095300    UP000092461    UP000235965    UP000002320    UP000008792   

PRIDE

G9LPT9    H9J7F0    H9J7F1    G9LPT8   

Pfam

PF00201   UDPGT        + More
PF00179   UQ_con
PF04101   Glyco_tran_28_C

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       
IPR023313   UBQ-conjugating_AS       
IPR000608   UBQ-conjugat_E2       
IPR016135   UBQ-conjugating_enzyme/RWD       
IPR007235   Glyco_trans_28_C       

SUPFAM

SSF54495   SSF54495       

Gene 3D

3.10.110.10    

CDD

cd00195  UBCc

ProteinModelPortal

G9LPT9   H9J7F0   A0A2H1W5A1   A0A191T1L9   H9J7F1   G9LPT8   + More
A0A2A4K0B3   A0A3S2N8S7   G9LPP9   A0A194QSA9   A0A2H4WB64   A0A212FL56   A0A1L8D6G2   A0A194PNY6   D2JLL0   A0A212EHV3   A0A2H4WB65   A0A182M8S5   A0A182R334   A0A182TC71   A0A182NJM1   A0A182Y289   A0A2M4BJX2   A0A2M4BJY0   A0A2M4BJY3   A0A182FDS8   A0A182I6Z1   A0A182JUT3   A0A182L3C8   A0A182VHN2   Q7PTF6   A0A182PQN3   A0A182WWQ5   A0A182WL35   A0A2M3Z343   A0A336K257   A0A182IJQ8   A0A2M3Z3U6   W5JEF5   A0A182QE42   A0A084WK54   A0A2M4AGW6   A0A2M4AFV3   A0A1B0DAR4   A0A2M4AGI4   A0A182TJ21   V5GU86   A0A1Q3FZT2   Q17GE2   A0A182GSW1   A0A1I8Q3X2   A0A182G7B7   A0A1B0CEV9   V5GQB1   A0A1Q3FRS4   A0A1Q3FZT9   Q17GE3   A0A2J7R4T0   B0W9Y5   A0A182SPP8   A0A1S4FQK6   V5I8H8   Q16T56   A0A2J7R4W5   A0A1Q3FR21   A0A1Y1MYW5   A0A182SBM5   Q16T58   A0A182G119   Q17KZ7   A0A182G120   A0A1B0DAR3   A0A336LRS6   L7WMY4   A0A1Y1NF76   A0A1Y9HEP2   A0A023EW79   A0A1S4EZ13   A0A1Y1MYZ1   Q1HRH8   A0A2M4CMN6   B4LYF5   T1PD10   A0A1Y1LHF3   A0A182IIM5   A0A182GYX7   A0A1Q3FQK2   A0A182Y290   A0A1W7R8H2   A0A1S4GSA2   A0A2J7R4W2   A0A2Z4LZD7   A0A1B0DAR5   A0A182FDS7   A0A182RHS4   A0A1L8E195   Q7Q5T0   W5JWX5   A0A2J7Q382   A0A1I8P2N0  

PDB

2O6L     E-value=1.80181e-25,     Score=287

KEGG

100862811    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT39C1; UDP-glycosyltransferase UGT39C1

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0016758   GO:0015020   GO:0005524   GO:0043231   GO:0008194   GO:0008152   GO:0046983   GO:0051536   GO:0006310   GO:0003676   GO:0006418   GO:0009058   GO:0016742   GO:0003824  

Subcellular location

Membrane  

Length:

320

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

32.87868

Exp number, first 60 AAs:

0.00711

Total prob of N-in:

0.46196

outside

1  -  269

TMhelix

270  -  292

inside

293  -  320

 

 

Pi

42.524394

Theta

31.584018

Tajima's D

1.296613

CLR

0.276507

CSRT

0.737163141842908

Interpretation

Uncertain