Gene

KWMTBOMO04461

Pre Gene Modal

BGIBMGA005429

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_acylphosphatase-1-like_[Bombyx_mori]

Location

Bomo_Chr8(+):7053725-7054259      View in EpiBrowser

Full name

Acylphosphatase       + More
Acylphosphatase-1      

Alternative Name

Acylphosphate phosphohydrolase 1
Acylphosphatase, organ-common type isozyme

Location in the cell

Cytoplasmic   Reliability : 2.232

CDS

ATGATGGCAGTGAACAAAGTAAATAGTGTAACGGCGGATTTCGAAGTTTTTGGAAAAGTGCAAGGAGTATTCTTCAGGAAGTTTACGCAAAAGAAAGCATTAGAACTTGGACTTAAGGGATGGGTAATGAATACGGCGCAAGGAACTGTTATAGGTCAACTTCAAGGACCCTCGACTGCTGTTGATGACATGAAGCTTTGGTTACAAAAGGTCGGAAGCCCAAAATCTAAGATCGAGAAAGCGGCGTTCAGGAATGAGGGAAATATTAAATGCTGCGCTTTTAGGACATTTGAAATACGTAAATGA

Protein

MMAVNKVNSVTADFEVFGKVQGVFFRKFTQKKALELGLKGWVMNTAQGTVIGQLQGPSTAVDDMKLWLQKVGSPKSKIEKAAFRNEGNIKCCAFRTFEIRK

Catalytic Activity

an acyl phosphate + H2O = a carboxylate + H(+) + phosphate
ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]

Cofactor

Mg(2+)

Similarity

Belongs to the acylphosphatase family.

Keywords

Complete proteome   Hydrolase   Reference proteome   Acetylation   Alternative initiation   Direct protein sequencing  

Feature

chain  Acylphosphatase
splice variant  In isoform ACYA.

Uniprot

A0A2H1WKS3   A0A0L7L3Z0   A0A194QSY6   A0A194PTH0   A0A154P670   E2C2U7   + More
A0A194RME9   A0A194PM78   A0A151J0Y4   E1ZUY9   E9IIG8   A0A3L8DJ57   A0A151IBR8   A0A2A3ECT4   A0A088AM18   A0A151XHU8   T1IQP0   H3BG22   A0A212FLH6   A0A158NM38   A0A3B4B462   G1K3F8   B7ZSP5   A0A195B5B9   Q28FK7   A0A2H1V3B6   A0A232FK13   A0A151JV39   A0A0V0TJU1   A0A0V1D3B6   A0A0V1P7T1   A0A0V1JCU3   A0A0A9Y5B4   K7IUV6   A0A0V0XVY6   A0A0V1IXS4   A0A2P8YBJ7   A0A2G9RF53   B5G0Z0   A0A0L7RIB7   A0A3M7SEY4   A0A0C9R1Q2   A0A0V1D315   A0A0V0TJJ9   A0A0V1P7U8   A0A0V1D3G0   A0A0V0TJW4   A0A0V1P8G2   A0A0V0WKQ2   A0A0V0ZF83   A0A0V0SA42   A0A0V0SA05   A0A0V0S9Y9   A0A0V0S9Z5   A0A0V0SAZ7   A0A0V0SA69   A0A0V0SA20   B5G0Y8   A0A1S3J2T5   A0A2C9L6Q8   B5G0Y4   A0A060WLS8   B5G0Y6   A0A1L8F0L9   Q6DE05   A0A210PXJ7   A0A3Q2GRF1   W4Y3L6   B5G0Y7   A0A3Q3E0V9   M7BRE4   A0A2A4IZ47   A0A2A4IZ85   A0A1U8DBG4   H0ZPP1   A0A3Q2CJM0   A0A1V4KFQ5   A0A3Q3Q983   U3JV14   A0A1I8MYG9   G1NJC9   A0A3Q2ZE24   A0A3Q0RQ50   A0A0L0CG51   P24540   P24540-2   A0A085NMQ5   A0A1S3SPT5   A0A2P4SWE6   B3M373   A0A218VDH1   A0A077Z9X3   A0A0V1FSM1   A0A0V1MYP3   A0A0V1MY60   A0A1Z5LGQ1   A0A3S2M122   A0A2T7NYF4   B5G0Z3  

EC Number

3.6.1.7

Pubmed

26227816    26354079    20798317    21282665    30249741    9215903    + More
22118469    21347285    25463417    20431018    28648823    25401762    20075255    29403074    17018643    30375419    15562597    24755649    27762356    28812685    23624526    20360741    25315136    20838655    26108605    1664426    24929829    17994087    28528879   

EMBL

ODYU01009237    SOQ53512.1    JTDY01003170    KOB70019.1    KQ461154    KPJ08434.1    + More
KQ459599    KPI94430.1    KQ434826    KZC07435.1    GL452203    EFN77782.1    KQ460205    KPJ17166.1    KQ459601    KPI94088.1    KQ980586    KYN15242.1    GL434335    EFN74987.1    GL763491    EFZ19644.1    QOIP01000007    RLU20381.1    KQ978079    KYM97165.1    KZ288282    PBC29565.1    KQ982109    KYQ59984.1    JH431312    AFYH01003232    AGBW02007799    OWR54550.1    ADTU01020221    AAMC01082889    BC170595    BC170599    AAI70595.1    KQ976604    KYM79384.1    CR761924    ODYU01000477    SOQ35333.1    NNAY01000115    OXU30839.1    KQ981730    KYN36606.1    JYDJ01000240    KRX39200.1    JYDI01000048    KRY55963.1    JYDM01000036    KRZ92266.1    JYDV01000108    KRZ32807.1    GBHO01016240    JAG27364.1    AAZX01010110    JYDU01000120    KRX92075.1    JYDS01000069    KRZ27543.1    PYGN01000725    PSN41638.1    KV943286    PIO26542.1    DQ215272    ACH44951.1    KQ414584    KOC70610.1    REGN01001486    RNA34384.1    GBYB01010064    JAG79831.1    KRY55964.1    KRX39199.1    KRZ92265.1    KRY55966.1    KRX39201.1    KRZ92267.1    JYDK01000102    KRX76369.1    JYDQ01000206    KRY11128.1    JYDL01000023    KRX23543.1    KRX23544.1    KRX23540.1    KRX23545.1    KRX23541.1    KRX23546.1    KRX23542.1    DQ215269    ACH44949.1    DQ215264    ACH44945.1    FR904607    CDQ68007.1    DQ215266    DQ215273    DQ215274    ACH44947.1    CM004481    OCT65132.1    BC077342    NEDP02005416    OWF41196.1    AAGJ04104659    DQ215268    DQ215270    ACH44948.1    KB548684    EMP30702.1    NWSH01005123    PCG64422.1    PCG64423.1    ABQF01003045    LSYS01003385    OPJ83235.1    AGTO01010448    JRES01000519    KNC30459.1    KL363220    KL367486    KFD53103.1    KFD70751.1    PPHD01019330    POI28437.1    CH902617    EDV43534.2    MUZQ01000005    OWK64115.1    HG806056    CDW56574.1    JYDT01000036    KRY89028.1    JYDO01000026    KRZ76707.1    KRZ76711.1    GFJQ02000387    JAW06583.1    RSAL01000081    RVE48579.1    PZQS01000008    PVD26184.1    DQ215275    ACH44954.1   

Proteomes

UP000037510    UP000053240    UP000053268    UP000076502    UP000008237    UP000078492    + More
UP000000311    UP000279307    UP000078542    UP000242457    UP000005203    UP000075809    UP000008672    UP000007151    UP000005205    UP000261520    UP000008143    UP000078540    UP000215335    UP000078541    UP000055048    UP000054653    UP000054924    UP000054826    UP000002358    UP000054815    UP000054805    UP000245037    UP000053825    UP000276133    UP000054673    UP000054783    UP000054630    UP000085678    UP000076420    UP000193380    UP000186698    UP000242188    UP000265020    UP000007110    UP000261660    UP000031443    UP000218220    UP000189705    UP000007754    UP000190648    UP000261600    UP000016665    UP000095301    UP000001645    UP000264820    UP000261340    UP000037069    UP000008227    UP000087266    UP000007801    UP000197619    UP000030665    UP000054995    UP000054843    UP000283053    UP000245119   

PRIDE

P24540   

Pfam

PF00708   Acylphosphatase        + More
PF05761   5_nucleotid
PF00041   fn3
PF07714   Pkinase_Tyr

Interpro

IPR020456   Acylphosphatase        + More
IPR001792   Acylphosphatase-like_dom       
IPR036046   Acylphosphatase-like_dom_sf       
IPR017968   Acylphosphatase_CS       
IPR036412   HAD-like_sf       
IPR023214   HAD_sf       
IPR008380   HAD-SF_hydro_IG_5-nucl       
IPR016695   Pur_nucleotidase       
IPR003961   FN3_dom       
IPR017441   Protein_kinase_ATP_BS       
IPR013783   Ig-like_fold       
IPR011009   Kinase-like_dom_sf       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR036116   FN3_sf       
IPR000719   Prot_kinase_dom       
IPR020635   Tyr_kinase_cat_dom       
IPR011044   Quino_amine_DH_bsu       
IPR002011   Tyr_kinase_rcpt_2_CS       
IPR011047   Quinoprotein_ADH-like_supfam       
IPR008949   Isoprenoid_synthase_dom_sf       

SUPFAM

SSF54975   SSF54975        + More
SSF56784   SSF56784       
SSF50969   SSF50969       
SSF49265   SSF49265       
SSF56112   SSF56112       
SSF50998   SSF50998       
SSF48576   SSF48576       

Gene 3D

3.40.50.1000     2.60.40.10     1.10.600.10    

CDD

cd00063  FN3

ProteinModelPortal

A0A2H1WKS3   A0A0L7L3Z0   A0A194QSY6   A0A194PTH0   A0A154P670   E2C2U7   + More
A0A194RME9   A0A194PM78   A0A151J0Y4   E1ZUY9   E9IIG8   A0A3L8DJ57   A0A151IBR8   A0A2A3ECT4   A0A088AM18   A0A151XHU8   T1IQP0   H3BG22   A0A212FLH6   A0A158NM38   A0A3B4B462   G1K3F8   B7ZSP5   A0A195B5B9   Q28FK7   A0A2H1V3B6   A0A232FK13   A0A151JV39   A0A0V0TJU1   A0A0V1D3B6   A0A0V1P7T1   A0A0V1JCU3   A0A0A9Y5B4   K7IUV6   A0A0V0XVY6   A0A0V1IXS4   A0A2P8YBJ7   A0A2G9RF53   B5G0Z0   A0A0L7RIB7   A0A3M7SEY4   A0A0C9R1Q2   A0A0V1D315   A0A0V0TJJ9   A0A0V1P7U8   A0A0V1D3G0   A0A0V0TJW4   A0A0V1P8G2   A0A0V0WKQ2   A0A0V0ZF83   A0A0V0SA42   A0A0V0SA05   A0A0V0S9Y9   A0A0V0S9Z5   A0A0V0SAZ7   A0A0V0SA69   A0A0V0SA20   B5G0Y8   A0A1S3J2T5   A0A2C9L6Q8   B5G0Y4   A0A060WLS8   B5G0Y6   A0A1L8F0L9   Q6DE05   A0A210PXJ7   A0A3Q2GRF1   W4Y3L6   B5G0Y7   A0A3Q3E0V9   M7BRE4   A0A2A4IZ47   A0A2A4IZ85   A0A1U8DBG4   H0ZPP1   A0A3Q2CJM0   A0A1V4KFQ5   A0A3Q3Q983   U3JV14   A0A1I8MYG9   G1NJC9   A0A3Q2ZE24   A0A3Q0RQ50   A0A0L0CG51   P24540   P24540-2   A0A085NMQ5   A0A1S3SPT5   A0A2P4SWE6   B3M373   A0A218VDH1   A0A077Z9X3   A0A0V1FSM1   A0A0V1MYP3   A0A0V1MY60   A0A1Z5LGQ1   A0A3S2M122   A0A2T7NYF4   B5G0Z3  

PDB

2ACY     E-value=7.01404e-23,     Score=258

KEGG

101743474    K01512 acylphosphatase [EC:3.6.1.7] | (RefSeq) acylphosphatase-1-like

PATHWAY

00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0003998   GO:0046872   GO:0005524   GO:0007169   GO:0004714   GO:0016021   GO:0006814   GO:0016020   GO:0006281   GO:0008270   GO:0004812   GO:0006418   GO:0009058   GO:0016742   GO:0003824  

PANTHER

PTHR10029   PTHR12103  

Length:

101

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06214

Exp number, first 60 AAs:

0.06208

Total prob of N-in:

0.55036

inside

1  -  101

 

 

Pi

28.523609

Theta

31.288209

Tajima's D

-0.272402

CLR

2.490125

CSRT

0.301184940752962

Interpretation

Uncertain