Gene

KWMTBOMO04455

Pre Gene Modal

BGIBMGA005424

Annotation

hypothetical_protein_KGM_06855_[Danaus_plexippus]

Location

Bomo_Chr8(+):6955645-6992614      View in EpiBrowser

Full name

Protein kinase C      

Location in the cell

PlasmaMembrane   Reliability : 4.94

CDS

ATGAAATGCGATGGAGCCCACGAAGCGATGCTCGGCAATGACAAATTGGCGAAAATCGCTAAACAAAAGCAGAAAGAATCAAATAAACAGGACGAATACGAAGCCCTACAGAGTTTCCTGCGCAGTATCAGCTCAACGGCCACATTACCACCATACGTCAAAGGAGAAACATACTCTTCCGTTCGGGGTGTATTCAATCAGTGCCTCATAACATGTGCAGTGTTGATCCTTGCCGCCGGTGCGGGTCATCCTATCGGTTTCTCAGCGATTGCTCTACCACAACTGCAGCGTGAGAATAGCTCTATGAGAACAGACGACGAGATGGGCTCTTGGATCGCCAGTATCCACTCGGCAGCTACCCCTCTCGGCTCGATGGTGTCAGGTCCGGTGATGGAAGCCATCGGGCGGCGGCGGACGCTACAGTCCTGCACCGTCCCGCTGGTCGTTGGGTGGATCATAATAGGAACTGCGTCGCATCACGCTTTATTGCTCCTTGGTAGAATTGTCTGTGGCTTCGCTGTAGGCCTCATGGCCGCTCCGTCACAGGTCTATTTGGGTGAAATATCTGAGCCCAGATTACGAGGTCTACTAATTGGAACTCCGTTTGTTGCATATTCTCTTGGAGTGTTGTACGTTTACACCCTGGGCGGTCCCCTTAGTTGGAGGTCCGTTGCATATCTCTCCACTGTACTCCCAATATTAGCATTTATTGCTCTATGCTTCTCTCCGGAAAGCCCGACATGGTTGGCTAGAAGAGGAAGATTCCACGAGGCCATGGCAGCGATGTCACGACTCCGAGGCACTACTGAAACGGCACAACGAGAACTCCATGAATTAATATCATGTCGGGAGAAGGAGAAAGCGCGAGGGGAAGAGAATATCAAATTCTTCGCAACTGTCATTCGATCCCCTGTGTTGAAACCACTGATTCTGATCAACACGTTCAACTTACTGCAGATTCTGTCAGGAAGTTATGTCGTTATATTTTATGCCATCAAAATTGTTGAAGAAGCCGGCGGTTCTCTGCCGCCTGAGATGGCAGCCAACGCAAGCGCTTTAGTAAGGTTAGCAGTGACGATCCTCGCTTGCATCTTGTTACTGCGGCTCACTCGTCGGACACTCGTCATGATTTCTGGCATTGGAACTTCTGTCTGTACTCTGGCGTTGGCCGCCCTACTCGCGCAAGGCCCCGGTACAGGCATCGCGCCGCCAGTCCTGATCCTCGCATACGTTGGCTTCAATACCTTAGGATTCTTTGTACTGCCGGGGCTTATGATAGGCGAATTACTGCCCACCAAAGTCCGTGGGCTCTGCGGAGGCTATATTTTCTGTTTCTTTAATTCATTCCTTTTTGGTTTTACCAAACTTTACCCTGCGATGATGAAGAATATAGGAATAGCGGCTGTCTTTAGTTTCTTCGGTATTTCCGCTGCTCTTGCCACAATTCTACTTTTCCTTTTATTACCAGAGACGAAAGGGAAATCTCTTTTACAAATAGAACAGTATTATCAAAAGCCGAATATATTGTGGCTGTCTCGTAAAAAAACAACCGGTAGTCAAAACGTTTGA

Protein

MKCDGAHEAMLGNDKLAKIAKQKQKESNKQDEYEALQSFLRSISSTATLPPYVKGETYSSVRGVFNQCLITCAVLILAAGAGHPIGFSAIALPQLQRENSSMRTDDEMGSWIASIHSAATPLGSMVSGPVMEAIGRRRTLQSCTVPLVVGWIIIGTASHHALLLLGRIVCGFAVGLMAAPSQVYLGEISEPRLRGLLIGTPFVAYSLGVLYVYTLGGPLSWRSVAYLSTVLPILAFIALCFSPESPTWLARRGRFHEAMAAMSRLRGTTETAQRELHELISCREKEKARGEENIKFFATVIRSPVLKPLILINTFNLLQILSGSYVVIFYAIKIVEEAGGSLPPEMAANASALVRLAVTILACILLLRLTRRTLVMISGIGTSVCTLALAALLAQGPGTGIAPPVLILAYVGFNTLGFFVLPGLMIGELLPTKVRGLCGGYIFCFFNSFLFGFTKLYPAMMKNIGIAAVFSFFGISAALATILLFLLLPETKGKSLLQIEQYYQKPNILWLSRKKTTGSQNV

Catalytic Activity

ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Similarity

Belongs to the membrane-bound acyltransferase family.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

Uniprot

H9J7D2   A0A212F561   A0A3S2NBT7   A0A2H1VQR6   A0A194RH13   A0A194PNB3   + More
A0A2A4IZE6   A0A182JVB0   A0A182IM61   A0A182RGI9   A0A182QYL2   A0A1S4FT49   A0A182Y1Z9   A0A182PRA4   A0A1B0CEP4   A0A1L8DFD0   A0A182M1R2   A0A1L8DF83   E2A4J1   A0A182WZA8   A0A1C7CZM0   A0A182NPD2   T1PIT2   A0A1I8NGC6   A0A182HPW0   A0A182U1D7   A0A182UQN7   A0A026W393   A0A182UBV2   A0A182FW58   A0A182SB54   W5JJV0   Q7Q024   A0A2J7QE56   A0A2M4AEH4   D6X016   A0A2M4AEJ1   A0A2M4AEY6   A0A2P8XF39   A0A2M4CN26   A0A0L0CQE9   A0A1I8NN12   A0A2M4AFX6   A0A1A9XP26   A0A1B0BNI6   E2B9R1   A0A151WLJ9   A0A1B0G7Q1   A0A1A9ZWD8   A0A1A9V8D1   A0A2M4BIF5   A0A182W9C7   A0A151IXJ2   A0A2M4BLV3   A0A195FQL9   B4PA70   B4QAZ8   A0A1I8M1P2   Q8MLQ7   W8CAE6   B3NPS7   A0A195CU57   A0A1Y1L0W9   A0A1Q3G0C6   B4I8T7   Q0IEA9   A0A0A1XJU0   F4WIX4   A0A034WQX0   A0A084WHI6   B4GBK8   A0A158N976   A0A3B0JXX9   B4LIZ5   A0A1J1ICI9   A0A0K8VSF9   B4KUC7   A0A1W4UMN4   A0A1W4V1P0   B4MYD6   B3ME82   A0A1Y1KX95   A0A1A9WIQ7   A0A0M4EV96   A0A0J7L656   B4JVU0   A0A0M9ADJ5   Q9W1J2   A0A0L7QJV6   A0A195B4K6   A0A2J7QE64   A0A182GZS3   A0A3L8DA70   A0A0A8J8P2   A0A1I8NN11   A0A067RK37   A0A1L8DDZ9   A0A1L8DDX2   A0A1Y1JT67  

EC Number

2.7.11.13

Pubmed

19121390    22118469    26354079    17510324    25244985    20798317    + More
20966253    25315136    24508170    20920257    23761445    12364791    14747013    17210077    18362917    19820115    29403074    26108605    17994087    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24495485    28004739    25830018    21719571    25348373    24438588    21347285    26483478    30249741    24845553   

EMBL

BABH01013656    BABH01013657    AGBW02010237    OWR48877.1    RSAL01000258    RVE43371.1    + More
ODYU01003876    SOQ43185.1    KQ460397    KPJ15221.1    KQ459599    KPI94478.1    NWSH01004606    PCG64856.1    AXCN02001824    AJWK01009053    GFDF01009040    JAV05044.1    AXCM01006009    GFDF01009039    JAV05045.1    GL436677    EFN71650.1    KA648015    AFP62644.1    APCN01003282    KK107455    EZA50493.1    ADMH02001285    ETN63180.1    AAAB01008986    EAA00109.4    NEVH01015327    PNF26868.1    GGFK01005863    MBW39184.1    KQ971372    EFA10509.1    GGFK01005862    MBW39183.1    GGFK01006019    MBW39340.1    PYGN01002375    PSN30621.1    GGFL01002536    MBW66714.1    JRES01000049    KNC34598.1    GGFK01006355    MBW39676.1    JXJN01017413    GL446584    EFN87595.1    KQ982959    KYQ48661.1    CCAG010016890    GGFJ01003681    MBW52822.1    KQ980796    KYN12965.1    GGFJ01004833    MBW53974.1    KQ981382    KYN42219.1    CM000158    EDW92396.1    CM000362    CM002911    EDX08435.1    KMY96121.1    AE013599    BT001766    AAM68271.2    AAN71521.1    GAMC01005816    JAC00740.1    CH954179    EDV56868.1    KQ977279    KYN04185.1    GEZM01071122    JAV66030.1    GFDL01001805    JAV33240.1    CH480824    EDW57012.1    CH477764    EAT36505.1    GBXI01003031    JAD11261.1    GL888177    EGI65920.1    GAKP01002260    JAC56692.1    ATLV01023839    ATLV01023840    ATLV01023841    KE525347    KFB49680.1    CH479181    EDW31303.1    ADTU01008811    ADTU01008812    OUUW01000001    SPP75948.1    CH940648    EDW60445.1    CVRI01000043    CRK96153.1    GDHF01010510    JAI41804.1    CH933808    EDW10714.2    CH963894    EDW77125.1    CH902619    EDV35477.2    GEZM01071123    JAV66029.1    CP012524    ALC41762.1    LBMM01000577    KMQ98038.1    CH916375    EDV98078.1    KQ435692    KOX81103.1    AY058792    AAL14021.1    KQ415067    KOC58831.1    KQ976618    KYM79197.1    PNF26866.1    JXUM01002147    JXUM01002148    QOIP01000010    RLU17395.1    AB901074    BAQ02374.1    KK852575    KDR20981.1    GFDF01009416    JAV04668.1    GFDF01009415    JAV04669.1    GEZM01101870    JAV52243.1   

Proteomes

UP000005204    UP000007151    UP000283053    UP000053240    UP000053268    UP000218220    + More
UP000075881    UP000075880    UP000075900    UP000075886    UP000076408    UP000075885    UP000092461    UP000075883    UP000000311    UP000076407    UP000075882    UP000075884    UP000095301    UP000075840    UP000075902    UP000075903    UP000053097    UP000069272    UP000075901    UP000000673    UP000007062    UP000235965    UP000007266    UP000245037    UP000037069    UP000095300    UP000092443    UP000092460    UP000008237    UP000075809    UP000092444    UP000092445    UP000078200    UP000075920    UP000078492    UP000078541    UP000002282    UP000000304    UP000000803    UP000008711    UP000078542    UP000001292    UP000008820    UP000007755    UP000030765    UP000008744    UP000005205    UP000268350    UP000008792    UP000183832    UP000009192    UP000192221    UP000007798    UP000007801    UP000091820    UP000092553    UP000036403    UP000001070    UP000053105    UP000053825    UP000078540    UP000069940    UP000279307    UP000027135   

PRIDE

H9J7D2    Q8MLQ7    Q9W1J2   

Pfam

PF00083   Sugar_tr        + More
PF03062   MBOAT
PF00433   Pkinase_C
PF00069   Pkinase
PF00130   C1_1

Interpro

IPR020846   MFS_dom        + More
IPR005829   Sugar_transporter_CS       
IPR036259   MFS_trans_sf       
IPR005828   MFS_sugar_transport-like       
IPR004299   MBOAT_fam       
IPR011009   Kinase-like_dom_sf       
IPR034659   Atypical_PKC       
IPR000719   Prot_kinase_dom       
IPR017892   Pkinase_C       
IPR020454   DAG/PE-bd       
IPR000961   AGC-kinase_C       
IPR008271   Ser/Thr_kinase_AS       
IPR002219   PE/DAG-bd       
IPR017441   Protein_kinase_ATP_BS       
IPR003663   Sugar/inositol_transpt       

SUPFAM

SSF103473   SSF103473        + More
SSF56112   SSF56112       

CDD

cd06174  MFS
cd00029  C1
cd05588  STKc_aPKC

ProteinModelPortal

H9J7D2   A0A212F561   A0A3S2NBT7   A0A2H1VQR6   A0A194RH13   A0A194PNB3   + More
A0A2A4IZE6   A0A182JVB0   A0A182IM61   A0A182RGI9   A0A182QYL2   A0A1S4FT49   A0A182Y1Z9   A0A182PRA4   A0A1B0CEP4   A0A1L8DFD0   A0A182M1R2   A0A1L8DF83   E2A4J1   A0A182WZA8   A0A1C7CZM0   A0A182NPD2   T1PIT2   A0A1I8NGC6   A0A182HPW0   A0A182U1D7   A0A182UQN7   A0A026W393   A0A182UBV2   A0A182FW58   A0A182SB54   W5JJV0   Q7Q024   A0A2J7QE56   A0A2M4AEH4   D6X016   A0A2M4AEJ1   A0A2M4AEY6   A0A2P8XF39   A0A2M4CN26   A0A0L0CQE9   A0A1I8NN12   A0A2M4AFX6   A0A1A9XP26   A0A1B0BNI6   E2B9R1   A0A151WLJ9   A0A1B0G7Q1   A0A1A9ZWD8   A0A1A9V8D1   A0A2M4BIF5   A0A182W9C7   A0A151IXJ2   A0A2M4BLV3   A0A195FQL9   B4PA70   B4QAZ8   A0A1I8M1P2   Q8MLQ7   W8CAE6   B3NPS7   A0A195CU57   A0A1Y1L0W9   A0A1Q3G0C6   B4I8T7   Q0IEA9   A0A0A1XJU0   F4WIX4   A0A034WQX0   A0A084WHI6   B4GBK8   A0A158N976   A0A3B0JXX9   B4LIZ5   A0A1J1ICI9   A0A0K8VSF9   B4KUC7   A0A1W4UMN4   A0A1W4V1P0   B4MYD6   B3ME82   A0A1Y1KX95   A0A1A9WIQ7   A0A0M4EV96   A0A0J7L656   B4JVU0   A0A0M9ADJ5   Q9W1J2   A0A0L7QJV6   A0A195B4K6   A0A2J7QE64   A0A182GZS3   A0A3L8DA70   A0A0A8J8P2   A0A1I8NN11   A0A067RK37   A0A1L8DDZ9   A0A1L8DDX2   A0A1Y1JT67  

PDB

4LDS     E-value=5.09738e-21,     Score=250

KEGG

101744194    K08145 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member

GO

GO:0016021   GO:0022857   GO:0008643   GO:0005887   GO:0005351   GO:0007163   GO:0035556   GO:0046872   GO:0004697   GO:0005524   GO:0005215   GO:0005737   GO:0006434   GO:0004812   GO:0006418   GO:0009058   GO:0016742   GO:0003824   GO:0055085  

Length:

522

Number of predicted TMHs:

10

Exp number of AAs in TMHs:

249.69816

Exp number, first 60 AAs:

0.02821

Total prob of N-in:

0.92861

inside

1  -  62

TMhelix

63  -  85

outside

86  -  163

TMhelix

164  -  186

inside

187  -  192

TMhelix

193  -  215

outside

216  -  224

TMhelix

225  -  242

inside

243  -  308

TMhelix

309  -  331

outside

332  -  345

TMhelix

346  -  368

inside

369  -  372

TMhelix

373  -  395

outside

396  -  404

TMhelix

405  -  427

inside

428  -  433

TMhelix

434  -  456

outside

457  -  465

TMhelix

466  -  488

inside

489  -  522

 

 

Pi

267.269352

Theta

178.407289

Tajima's D

1.40482

CLR

0.127666

CSRT

0.766261686915654

Interpretation

Uncertain