Gene
KWMTBOMO04453
Pre Gene Modal
BGIBMGA005423
Annotation
PREDICTED:_LOW_QUALITY_PROTEIN:_mediator_of_RNA_polymerase_II_transcription_subunit_1_[Papilio_machaon]
Full name
Mediator of RNA polymerase II transcription subunit 1
Alternative Name
Mediator complex subunit 1
Location in the cell
Nuclear Reliability : 3.66
Sequence
CDS
ATGATGTGTCAGGATTCGAACGAGTCTAAGCACCAGGAGGAACGGAAATCGAAAAAGCGAAAGTCTGATTCTGATGTATGGAGCACGGCGCAGAAGAAAGGCAAGCCCGGTTTGAGCGACATGATGGATTCGGACAGCGAGAGCGACAATTCCGATAATTACGCGAACGAAGACGACAATACCGTAAACAGTAATTCTAGTACCGAAGATTTGGAAGGCCGAGAGTCGTCCGCCTCGCAAAACGAATTCACGTCAGATCTAGAACTTTCCACGATGGACGCCGCGGACGCCTTGAGGAACCAGGATAACCGGACCTCGTCCGATATAGACAACTCGAACGATGGAGACGTCGAAGAAATTATGAGGAATTCTTTTCAGAAGTCTGATCACAAAAGGCAAAAACTTAAAAGTAAAGATTCGGAAATGAGAAGAAGCTCTTCTTCTTTGTTGCTCGATTTGACCGAAGGTAAATCGTACATGCCCTCGTCGGTCAGCATCACGCCCATCGGCAGTAGCTCCGCTAACCCGCAGCCTCCGTCGGGTGCCGGCATCTCTTCCATGCTGTGTCTCGACCGACGCCCCGGTATCGAGATCATACCGATCTCGGCGGCTGCTCCGGCCGCCCTGCCCAGTTCCATAACCATCACGCCTATCACGTCCTCGCAAATCAAATCTATGGACGATCGTATTAGGTCAGACAGGAAGTCCAGCAAATCCGGCGAGGAACGAAGCAAAGAGAAGAAGAAAAAACGCAGACGAGACGATTCGATGGGACCCCCGGAGAAAGTGCCTCCTAAGCAGGACCCGTTGACTAAGCCCGTATCAGTCAGTATCAAACCTACTGACGGCTCGCCCTTGCGTGCGTCGTCGCCGAACTCCCTGATCAGGAAATTCAGTCCGAGTCCAACGCACGGCCGTTCCGTGTCCATCACCAAATCACCGAGCCCTAGTACGGTCAAGGGCATAGGGAAACCGTCCGGCACGTCCAGCCACCACAGCAGCCCGCGACATTCACCGGTCCAAAATAGTCCGAAACATCTAACAGGCTATTCGAGTCCAAAAAACCACAGCATCTCTTCCCCTAAACAAAGCTCGTCCGGTTCAGGCAAGCCTAGTATGTCGGCTTTAAAATCGGCGACAAGCGGCTCTCCGTCTGCTAAATCCGGAACAACTGGTTACGATCTGACAAAAAAAATTTCGAAAGACAACTACAGCTCTAGCTCCTCAACCTCTAGGGATAAAGAAAAAAAACATTCCAGCCTCTCTTTTTCTAGTTCCGATCGGAGCAGTCCGAAATTAAAAAACCCCATGAAAATCAAACAGCTAGAAATAACTCCAGTTACCTGTGATAGTGCTGTGACGGAGCCATTGATTTCTCCGCCAAATATAGAAGTAAACAAACCCAATGCTAGCCAAGCGCGTAACAGAAAGGGCTCGCTGAGCGCTGTCATAGACAAACTTAAGTCGGCTCAACATTGTGGAGGGGATTCCGACTCGAGTTCGAAGTCCAGCGGCTCGTCAAGTAGCGTCGGTAAATTCTCGGAACAGAAAAACAGTTTACCCGCTAGCGGCGGCAAAACGAGCGAAAGTAAAAACCAAGAATACATGGTGAAACCAAGTTCGGACGGAATGAAGATCACCATCAACAAGACTCGCTCAAAGGAATCCAGTAGCAGTTCGAAATTAAACTATAGCTCTAGCAAACAATCATCTCCCCAGCTCACGCCTCCCAGTCAAGGCTCTCCAAAAACGCACACCGGCTTGAAACCTGGAGTTATTAGTGGACCGGCCTCTAAAAAGACCCAAGCCATGCAGTCTTCTAAATCCAGCAGTCTGAACACAAGCTCGACACCACCCAAAGCGAATATGAGTCCTTCGGATTCGAGTAATCCGAACATGTCTAAAGTGCCTTACTCTAAGTCATCCAGCAGTAGCAGTAGCGCTGGTATAAATCTTTCAAAATCTGCCTCCAAATCTAATTCGGGCTCGCCTAAAGGCAGTAGTTCAGATTTAGCGAAAATAATACGAGATCGTGAAAGAGAGAAAGCGCGAACGAAACTCATGAGTAATTCAGAAAAGTCTATATTTTCTTCGAAGTCTGAACGGCATTCTAGTCCGAGTGGCTCTAGAGACGACGTCGATGGCGACAGAATAAAATCTTCGAAAGATGTAAACTTTCGTGTTGAAGGCCTAATGAAACCTCTGGACACTCGAAACTTTCAAATTCCAAAACTAAAAGACAAAAATAGTCCCGCGGCGCAGTATGAAAACAGATCCATGGTAAATGATTTTTCACGTTCGCTTGACCAAAATAAATATCCTTTTTCGCATTACGATAATTCTAACAAAGGTTCCGAATCAATGCAAAAGTCGGCCTACCCTTTAAATGTACCAAAACCATTAATGAACTTAGGAGCAATGAGTCCTAAAACTACAGGTAAAAGTGATCAATCGGACAGACCCATGGAATATTCCAAAGCCACCGCAGACAGCCTTACCAAAGGCGGGAGTCCTCAGCGTAACAAGGACGAGGCCAAAGATGCTTATTCCAGTTCTTATCCTCTGATGCCACTCGATTTTAAAACGGATATGGCAAAGGGATTCGCTACTCCAAAAGGCGCCCCCGAAGACAGAAAAGGGGCCGACTCTTGTATGAAACCGCCCGCGAGCGCATCAGTGGCCCGCAGTGGGGCGACTACGCCTCAAGAAGCAGCAGAAATGCTATTAGATTTCTCCTCATCGTCCGGTAGTAAAGTTTCTGGCTTAGTAGCGGTCCGTCCCGTGTACCCTGCCTCTCCGGCCCTCGCCCTGCAATTAGCCAAGAGCCCTGCGCCTTCGCCCCTAGTAGCTCCGTCGCCTCATTCTAATTCACCTTGTATTACAGACGATGAACTCATAGATGAAGGATTAGTTGGTCCCGGTAAGTGA
Protein
MMCQDSNESKHQEERKSKKRKSDSDVWSTAQKKGKPGLSDMMDSDSESDNSDNYANEDDNTVNSNSSTEDLEGRESSASQNEFTSDLELSTMDAADALRNQDNRTSSDIDNSNDGDVEEIMRNSFQKSDHKRQKLKSKDSEMRRSSSSLLLDLTEGKSYMPSSVSITPIGSSSANPQPPSGAGISSMLCLDRRPGIEIIPISAAAPAALPSSITITPITSSQIKSMDDRIRSDRKSSKSGEERSKEKKKKRRRDDSMGPPEKVPPKQDPLTKPVSVSIKPTDGSPLRASSPNSLIRKFSPSPTHGRSVSITKSPSPSTVKGIGKPSGTSSHHSSPRHSPVQNSPKHLTGYSSPKNHSISSPKQSSSGSGKPSMSALKSATSGSPSAKSGTTGYDLTKKISKDNYSSSSSTSRDKEKKHSSLSFSSSDRSSPKLKNPMKIKQLEITPVTCDSAVTEPLISPPNIEVNKPNASQARNRKGSLSAVIDKLKSAQHCGGDSDSSSKSSGSSSSVGKFSEQKNSLPASGGKTSESKNQEYMVKPSSDGMKITINKTRSKESSSSSKLNYSSSKQSSPQLTPPSQGSPKTHTGLKPGVISGPASKKTQAMQSSKSSSLNTSSTPPKANMSPSDSSNPNMSKVPYSKSSSSSSSAGINLSKSASKSNSGSPKGSSSDLAKIIRDREREKARTKLMSNSEKSIFSSKSERHSSPSGSRDDVDGDRIKSSKDVNFRVEGLMKPLDTRNFQIPKLKDKNSPAAQYENRSMVNDFSRSLDQNKYPFSHYDNSNKGSESMQKSAYPLNVPKPLMNLGAMSPKTTGKSDQSDRPMEYSKATADSLTKGGSPQRNKDEAKDAYSSSYPLMPLDFKTDMAKGFATPKGAPEDRKGADSCMKPPASASVARSGATTPQEAAEMLLDFSSSSGSKVSGLVAVRPVYPASPALALQLAKSPAPSPLVAPSPHSNSPCITDDELIDEGLVGPGK
Summary
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 1 family.
Uniprot
Pubmed
EMBL
Proteomes
PRIDE
Pfam
PF10744 Med1
Interpro
IPR019680
Mediator_Med1
ProteinModelPortal
Ontologies
Topology
Subcellular location
Nucleus
Length:
975
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.07999
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00359
outside
1 - 975
Population Genetic Test Statistics
Pi
270.379533
Theta
226.246639
Tajima's D
0.542063
CLR
0.00651
CSRT
0.524023798810059
Interpretation
Uncertain
