Gene
KWMTBOMO04452
Pre Gene Modal
BGIBMGA005423
Annotation
hypothetical_protein_KGM_18357_[Danaus_plexippus]
Full name
Mediator of RNA polymerase II transcription subunit 1
+ More
XK-related protein
XK-related protein
Alternative Name
Mediator complex subunit 1
Location in the cell
Mitochondrial Reliability : 1.161 Nuclear Reliability : 1.733
Sequence
CDS
ATGACGGACGGAAACTTAATTATGACTGCGAACGGTCTTATAGATAAATCTAAAGAACTTCAAAAGGAAATCTTGATGGAGAAGTTAAGGTCTAAAACACCACAATATAAAAATTTGACCGAAACTTCTAAGGCTGTAAGAACATCTATGTTGGACAAGAGGTGGGGTGTTGATAATGCAGACAGGATGATTTTACAGAAGTGCTTAGATAGTTTGCAGCACAGTATAAAAATTACATCTCTACAAAACCTAATAGAAAGGCTTCAATGTCTTTCAAGACAGTTAGGATTAAAATTAGTAGTTGGCACTTCAGGAGTAAACTTGTTCATATCATCAGATATGTTTTATTTAGAGATACTTGTAGAATCATCGGGTTCCGTAAAAGATGTCAAAATACATCATGAAGGAAAGATCGAACAACAAAGTTGTGAAGAATTGGTACACTGTATATCAGCTGGAGATTTCACAGATTTTACAGCACAATTAGAAGGTTTGACTGCTGTTTATCAACTTAATGCTGAGAAAAAGGTGAAATGTAAAGCATTCACTGCCCTTCAGAGCTTGGAAGATGACCTGTGTACGTTACGACAATTACAGAGTTTTATAAAAGATCCTTGGGCACAAGTACACAAGAGTCCCATAGGTTTTCTTCAGAAACGTAGAGGAGGTCACGCGATGCGTCTAACGTACTTCGTTTCACCATACGAGCTATTAGACAAAGACGCGGGCCTACAGCCTCTCACGACTGAACTCTTGACGACCGGGAAACCTACGGCATCCAACGGCTTCGCTTCACACGGCACACCCGCCTACACTCCTATAGGTCATTCCGCCACTGTCTTATTAGAAGGCTCCACTGCCAATAAACTGCAGTTATCGACTATTATATCAAATGCCCAACGATCTGGAAAAAGCAACGGTCCCGTATACGCGCCACTGGTACCCCAGAACAGTGCGATGCTGCCGGCTTGCTTCACCCTCAAACTGTCGCAGCCGACGCCGCTGTGCTCGGGCCTAGCGAAATTAATACAAGCCACGACAGAGGTGGAAGTGTCTGGCGACTGGGCAAACGCCAAACCGTTGTTAGGGCTGGTCGTACAACAAGCGTACGATAAACTCGTGCCCGGCAAGAATATTGAGTTGAATCTCAGTAAAGGACTGTTTGTTAACCTACCGAAGCAGACTCAGTGCTACTTTGTATGTGAGCGGCGCGGGCTGGAGGGTTGCATTGTAAACAGCGTCCCGTTCACGCACCCGTCGCACGTGGCAGCCCTGCTGGCGTGTCTGCGGCAGCAGGCGCTCTTCAACACGTTGCTCGCGAGCTGCGTACGGCTGCAGACCAAACTAGCTGTCGAACTCGAAAAGGTGTTGATGTTCGAAGTGAGCGCCCTCTCGTGGCAGCACATTTCTATATCGTTGGAACATCCGCTAGAAGAATGTATGGCCACCGTCGAACTTGAACTGTCGGATCCGGCCTCGCCCCGCGCGTCTGTGTACACGCTGAACAGTCCGGCTCGAGACCACATCGACGACTACATCACCAGGGTGCTGCAAAAGAGTCATTCTATACCAATAACGTTAAGGTCTCTCGTCAAGATATGGGAGCGCGAGGCCGCAGCGAAGCAGATGAACGGCGGCTACTCTGCCCTGGACTCGAATTTTAGTTGCGGCGTCGGCGGACTCGACCCCGGCGGCGAGCAGCTCAAGCACGAGCCCGCGCACCCGCACCGCGCGCTCTACCCGCACCCGCACCACGCCGGTAACCATGCCTCCCCTACTCTTATACATAACATTACAGATCTCTCTCTCGTATATACCTAG
Protein
MTDGNLIMTANGLIDKSKELQKEILMEKLRSKTPQYKNLTETSKAVRTSMLDKRWGVDNADRMILQKCLDSLQHSIKITSLQNLIERLQCLSRQLGLKLVVGTSGVNLFISSDMFYLEILVESSGSVKDVKIHHEGKIEQQSCEELVHCISAGDFTDFTAQLEGLTAVYQLNAEKKVKCKAFTALQSLEDDLCTLRQLQSFIKDPWAQVHKSPIGFLQKRRGGHAMRLTYFVSPYELLDKDAGLQPLTTELLTTGKPTASNGFASHGTPAYTPIGHSATVLLEGSTANKLQLSTIISNAQRSGKSNGPVYAPLVPQNSAMLPACFTLKLSQPTPLCSGLAKLIQATTEVEVSGDWANAKPLLGLVVQQAYDKLVPGKNIELNLSKGLFVNLPKQTQCYFVCERRGLEGCIVNSVPFTHPSHVAALLACLRQQALFNTLLASCVRLQTKLAVELEKVLMFEVSALSWQHISISLEHPLEECMATVELELSDPASPRASVYTLNSPARDHIDDYITRVLQKSHSIPITLRSLVKIWEREAAAKQMNGGYSALDSNFSCGVGGLDPGGEQLKHEPAHPHRALYPHPHHAGNHASPTLIHNITDLSLVYT
Summary
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subunit
Component of the Mediator complex.
Similarity
Belongs to the Mediator complex subunit 1 family.
Belongs to the XK family.
Belongs to the XK family.
Keywords
Activator
Complete proteome
Nucleus
Reference proteome
Transcription
Transcription regulation
Feature
chain Mediator of RNA polymerase II transcription subunit 1
Uniprot
H9J7D1
A0A212FJB1
A0A2A4IVE6
A0A2H1V7W8
A0A194PTL6
A0A194RCM4
+ More
A0A2A4IY88 A0A3S2TQ75 A0A0L7LV46 A0A1Y1L2C4 A0A1Y1L3E5 A0A1B6HEG6 A0A1B6C1M1 D6WVF3 A0A0C9R6G8 A0A2A3E659 A0A1B6LVM8 A0A088AEF8 A0A0L7QV40 A0A067R849 A0A0C9RFL1 A0A2J7PH68 A0A310S8K6 A0A1W4W4H1 A0A069DY85 A0A2P8Y0H7 A0A224XHT3 A0A023EZ27 A0A232F1Z6 A0A3L8DJ51 A0A146MAZ0 A0A0J7KYK3 N6TS83 A0A158NM56 U4U837 A0A151JT69 T1HHG1 A0A151XJR6 A0A146M7I1 A0A151IE93 A0A151J5B5 A0A195BWW4 A0A154PRC4 E2A6Z0 A0A0M8ZSX2 A0A1L8DHP9 A0A1B6DYB0 A0A034VJN8 A0A2R7WXN7 W8B530 A0A1L8DHE3 E0W419 A0A0K8VRE4 A0A0A1WFT1 A0A0A1XCC0 K7J0T4 A0A1B0D573 W4VS65 V5HBA4 A0A0P4VK26 A0A147BGL6 T1J8I3 Q172G3 A0A1I8NF68 A0A1I8NWS4 A0A182H4P0 F4WYN8 A0A1A9W550 A0A2R5LLT1 A0A0L0C5M4 A0A182PRA6 A0A1A9XT23 Q7PVB4 A0A1B0AKR2 A0A1B0AIE4 A0A1B0FBS1 A0A1A9VAP9 J9JYA5 A0A131Z6B4 A0A182LXJ0 A0A1S4H9T3 A0A182WZB0 A0A2S2R9G5 A0A182JVA8 A0A2H8TJ81 A0A182HPW2 A0A182TX53 A0A182UUA4 A0A182Y1Z7 A0A182RGJ1 A0A182W9C5 A0A182NPD4 A0A0A9YZK2 A0A0K8SA70 A0A0K8S9W9 A0A182IKS5
A0A2A4IY88 A0A3S2TQ75 A0A0L7LV46 A0A1Y1L2C4 A0A1Y1L3E5 A0A1B6HEG6 A0A1B6C1M1 D6WVF3 A0A0C9R6G8 A0A2A3E659 A0A1B6LVM8 A0A088AEF8 A0A0L7QV40 A0A067R849 A0A0C9RFL1 A0A2J7PH68 A0A310S8K6 A0A1W4W4H1 A0A069DY85 A0A2P8Y0H7 A0A224XHT3 A0A023EZ27 A0A232F1Z6 A0A3L8DJ51 A0A146MAZ0 A0A0J7KYK3 N6TS83 A0A158NM56 U4U837 A0A151JT69 T1HHG1 A0A151XJR6 A0A146M7I1 A0A151IE93 A0A151J5B5 A0A195BWW4 A0A154PRC4 E2A6Z0 A0A0M8ZSX2 A0A1L8DHP9 A0A1B6DYB0 A0A034VJN8 A0A2R7WXN7 W8B530 A0A1L8DHE3 E0W419 A0A0K8VRE4 A0A0A1WFT1 A0A0A1XCC0 K7J0T4 A0A1B0D573 W4VS65 V5HBA4 A0A0P4VK26 A0A147BGL6 T1J8I3 Q172G3 A0A1I8NF68 A0A1I8NWS4 A0A182H4P0 F4WYN8 A0A1A9W550 A0A2R5LLT1 A0A0L0C5M4 A0A182PRA6 A0A1A9XT23 Q7PVB4 A0A1B0AKR2 A0A1B0AIE4 A0A1B0FBS1 A0A1A9VAP9 J9JYA5 A0A131Z6B4 A0A182LXJ0 A0A1S4H9T3 A0A182WZB0 A0A2S2R9G5 A0A182JVA8 A0A2H8TJ81 A0A182HPW2 A0A182TX53 A0A182UUA4 A0A182Y1Z7 A0A182RGJ1 A0A182W9C5 A0A182NPD4 A0A0A9YZK2 A0A0K8SA70 A0A0K8S9W9 A0A182IKS5
Pubmed
19121390
22118469
26354079
26227816
28004739
18362917
+ More
19820115 24845553 26334808 29403074 25474469 28648823 30249741 26823975 23537049 21347285 20798317 25348373 24495485 20566863 25830018 20075255 25765539 27129103 29652888 17510324 25315136 26483478 21719571 26108605 12364791 26830274 25244985 25401762
19820115 24845553 26334808 29403074 25474469 28648823 30249741 26823975 23537049 21347285 20798317 25348373 24495485 20566863 25830018 20075255 25765539 27129103 29652888 17510324 25315136 26483478 21719571 26108605 12364791 26830274 25244985 25401762
EMBL
BABH01013651
BABH01013652
AGBW02008294
OWR53822.1
NWSH01006134
PCG63639.1
+ More
ODYU01000954 SOQ36492.1 KQ459599 KPI94480.1 KQ460397 KPJ15224.1 NWSH01005550 PCG64132.1 RSAL01000025 RVE52122.1 JTDY01000068 KOB79066.1 GEZM01071040 JAV66105.1 GEZM01071038 JAV66106.1 GECU01034671 JAS73035.1 GEDC01030119 JAS07179.1 KQ971357 EFA08558.1 GBYB01011924 JAG81691.1 KZ288355 PBC27227.1 GEBQ01012248 JAT27729.1 KQ414734 KOC62331.1 KK852680 KDR18637.1 GBYB01011922 GBYB01011923 JAG81689.1 JAG81690.1 NEVH01025149 PNF15674.1 KQ770367 OAD52651.1 GBGD01000083 JAC88806.1 PYGN01001082 PSN37768.1 GFTR01008827 JAW07599.1 GBBI01004245 JAC14467.1 NNAY01001205 OXU24744.1 QOIP01000007 RLU20366.1 GDHC01002909 JAQ15720.1 LBMM01002028 KMQ95373.1 APGK01056848 KB741277 ENN71171.1 ADTU01020292 KB632155 ERL89217.1 KQ981960 KYN31903.1 ACPB03009329 KQ982060 KYQ60577.1 GDHC01004109 JAQ14520.1 KQ977890 KYM99001.1 KQ980039 KYN18135.1 KQ976395 KYM93072.1 KQ435012 KZC13828.1 GL437208 EFN70793.1 KQ435908 KOX68963.1 GFDF01008204 JAV05880.1 GEDC01006638 JAS30660.1 GAKP01016620 JAC42332.1 KK855897 PTY24298.1 GAMC01010300 JAB96255.1 GFDF01008206 JAV05878.1 DS235886 EEB20375.1 GDHF01010860 JAI41454.1 GBXI01016972 JAC97319.1 GBXI01005228 JAD09064.1 AJVK01003343 AJVK01003344 GANO01000023 JAB59848.1 GANP01003763 JAB80705.1 GDKW01001950 JAI54645.1 GEGO01005520 JAR89884.1 JH431954 CH477438 JXUM01025434 KQ560722 KXJ81143.1 GL888455 EGI60673.1 GGLE01006364 MBY10490.1 JRES01000889 KNC27547.1 AAAB01008986 EAA00108.5 JXJN01023294 JXJN01026971 CCAG010017146 ABLF02041154 GEDV01001638 JAP86919.1 AXCM01006009 GGMS01017381 MBY86584.1 GFXV01002275 MBW14080.1 APCN01003282 GBHO01007081 JAG36523.1 GBRD01015792 JAG50034.1 GBRD01015745 JAG50081.1
ODYU01000954 SOQ36492.1 KQ459599 KPI94480.1 KQ460397 KPJ15224.1 NWSH01005550 PCG64132.1 RSAL01000025 RVE52122.1 JTDY01000068 KOB79066.1 GEZM01071040 JAV66105.1 GEZM01071038 JAV66106.1 GECU01034671 JAS73035.1 GEDC01030119 JAS07179.1 KQ971357 EFA08558.1 GBYB01011924 JAG81691.1 KZ288355 PBC27227.1 GEBQ01012248 JAT27729.1 KQ414734 KOC62331.1 KK852680 KDR18637.1 GBYB01011922 GBYB01011923 JAG81689.1 JAG81690.1 NEVH01025149 PNF15674.1 KQ770367 OAD52651.1 GBGD01000083 JAC88806.1 PYGN01001082 PSN37768.1 GFTR01008827 JAW07599.1 GBBI01004245 JAC14467.1 NNAY01001205 OXU24744.1 QOIP01000007 RLU20366.1 GDHC01002909 JAQ15720.1 LBMM01002028 KMQ95373.1 APGK01056848 KB741277 ENN71171.1 ADTU01020292 KB632155 ERL89217.1 KQ981960 KYN31903.1 ACPB03009329 KQ982060 KYQ60577.1 GDHC01004109 JAQ14520.1 KQ977890 KYM99001.1 KQ980039 KYN18135.1 KQ976395 KYM93072.1 KQ435012 KZC13828.1 GL437208 EFN70793.1 KQ435908 KOX68963.1 GFDF01008204 JAV05880.1 GEDC01006638 JAS30660.1 GAKP01016620 JAC42332.1 KK855897 PTY24298.1 GAMC01010300 JAB96255.1 GFDF01008206 JAV05878.1 DS235886 EEB20375.1 GDHF01010860 JAI41454.1 GBXI01016972 JAC97319.1 GBXI01005228 JAD09064.1 AJVK01003343 AJVK01003344 GANO01000023 JAB59848.1 GANP01003763 JAB80705.1 GDKW01001950 JAI54645.1 GEGO01005520 JAR89884.1 JH431954 CH477438 JXUM01025434 KQ560722 KXJ81143.1 GL888455 EGI60673.1 GGLE01006364 MBY10490.1 JRES01000889 KNC27547.1 AAAB01008986 EAA00108.5 JXJN01023294 JXJN01026971 CCAG010017146 ABLF02041154 GEDV01001638 JAP86919.1 AXCM01006009 GGMS01017381 MBY86584.1 GFXV01002275 MBW14080.1 APCN01003282 GBHO01007081 JAG36523.1 GBRD01015792 JAG50034.1 GBRD01015745 JAG50081.1
Proteomes
UP000005204
UP000007151
UP000218220
UP000053268
UP000053240
UP000283053
+ More
UP000037510 UP000007266 UP000242457 UP000005203 UP000053825 UP000027135 UP000235965 UP000192223 UP000245037 UP000215335 UP000279307 UP000036403 UP000019118 UP000005205 UP000030742 UP000078541 UP000015103 UP000075809 UP000078542 UP000078492 UP000078540 UP000076502 UP000000311 UP000053105 UP000009046 UP000002358 UP000092462 UP000008820 UP000095301 UP000095300 UP000069940 UP000249989 UP000007755 UP000091820 UP000037069 UP000075885 UP000092443 UP000007062 UP000092460 UP000092445 UP000092444 UP000078200 UP000007819 UP000075883 UP000076407 UP000075881 UP000075840 UP000075902 UP000075903 UP000076408 UP000075900 UP000075920 UP000075884 UP000075880
UP000037510 UP000007266 UP000242457 UP000005203 UP000053825 UP000027135 UP000235965 UP000192223 UP000245037 UP000215335 UP000279307 UP000036403 UP000019118 UP000005205 UP000030742 UP000078541 UP000015103 UP000075809 UP000078542 UP000078492 UP000078540 UP000076502 UP000000311 UP000053105 UP000009046 UP000002358 UP000092462 UP000008820 UP000095301 UP000095300 UP000069940 UP000249989 UP000007755 UP000091820 UP000037069 UP000075885 UP000092443 UP000007062 UP000092460 UP000092445 UP000092444 UP000078200 UP000007819 UP000075883 UP000076407 UP000075881 UP000075840 UP000075902 UP000075903 UP000076408 UP000075900 UP000075920 UP000075884 UP000075880
SUPFAM
SSF48371
SSF48371
ProteinModelPortal
H9J7D1
A0A212FJB1
A0A2A4IVE6
A0A2H1V7W8
A0A194PTL6
A0A194RCM4
+ More
A0A2A4IY88 A0A3S2TQ75 A0A0L7LV46 A0A1Y1L2C4 A0A1Y1L3E5 A0A1B6HEG6 A0A1B6C1M1 D6WVF3 A0A0C9R6G8 A0A2A3E659 A0A1B6LVM8 A0A088AEF8 A0A0L7QV40 A0A067R849 A0A0C9RFL1 A0A2J7PH68 A0A310S8K6 A0A1W4W4H1 A0A069DY85 A0A2P8Y0H7 A0A224XHT3 A0A023EZ27 A0A232F1Z6 A0A3L8DJ51 A0A146MAZ0 A0A0J7KYK3 N6TS83 A0A158NM56 U4U837 A0A151JT69 T1HHG1 A0A151XJR6 A0A146M7I1 A0A151IE93 A0A151J5B5 A0A195BWW4 A0A154PRC4 E2A6Z0 A0A0M8ZSX2 A0A1L8DHP9 A0A1B6DYB0 A0A034VJN8 A0A2R7WXN7 W8B530 A0A1L8DHE3 E0W419 A0A0K8VRE4 A0A0A1WFT1 A0A0A1XCC0 K7J0T4 A0A1B0D573 W4VS65 V5HBA4 A0A0P4VK26 A0A147BGL6 T1J8I3 Q172G3 A0A1I8NF68 A0A1I8NWS4 A0A182H4P0 F4WYN8 A0A1A9W550 A0A2R5LLT1 A0A0L0C5M4 A0A182PRA6 A0A1A9XT23 Q7PVB4 A0A1B0AKR2 A0A1B0AIE4 A0A1B0FBS1 A0A1A9VAP9 J9JYA5 A0A131Z6B4 A0A182LXJ0 A0A1S4H9T3 A0A182WZB0 A0A2S2R9G5 A0A182JVA8 A0A2H8TJ81 A0A182HPW2 A0A182TX53 A0A182UUA4 A0A182Y1Z7 A0A182RGJ1 A0A182W9C5 A0A182NPD4 A0A0A9YZK2 A0A0K8SA70 A0A0K8S9W9 A0A182IKS5
A0A2A4IY88 A0A3S2TQ75 A0A0L7LV46 A0A1Y1L2C4 A0A1Y1L3E5 A0A1B6HEG6 A0A1B6C1M1 D6WVF3 A0A0C9R6G8 A0A2A3E659 A0A1B6LVM8 A0A088AEF8 A0A0L7QV40 A0A067R849 A0A0C9RFL1 A0A2J7PH68 A0A310S8K6 A0A1W4W4H1 A0A069DY85 A0A2P8Y0H7 A0A224XHT3 A0A023EZ27 A0A232F1Z6 A0A3L8DJ51 A0A146MAZ0 A0A0J7KYK3 N6TS83 A0A158NM56 U4U837 A0A151JT69 T1HHG1 A0A151XJR6 A0A146M7I1 A0A151IE93 A0A151J5B5 A0A195BWW4 A0A154PRC4 E2A6Z0 A0A0M8ZSX2 A0A1L8DHP9 A0A1B6DYB0 A0A034VJN8 A0A2R7WXN7 W8B530 A0A1L8DHE3 E0W419 A0A0K8VRE4 A0A0A1WFT1 A0A0A1XCC0 K7J0T4 A0A1B0D573 W4VS65 V5HBA4 A0A0P4VK26 A0A147BGL6 T1J8I3 Q172G3 A0A1I8NF68 A0A1I8NWS4 A0A182H4P0 F4WYN8 A0A1A9W550 A0A2R5LLT1 A0A0L0C5M4 A0A182PRA6 A0A1A9XT23 Q7PVB4 A0A1B0AKR2 A0A1B0AIE4 A0A1B0FBS1 A0A1A9VAP9 J9JYA5 A0A131Z6B4 A0A182LXJ0 A0A1S4H9T3 A0A182WZB0 A0A2S2R9G5 A0A182JVA8 A0A2H8TJ81 A0A182HPW2 A0A182TX53 A0A182UUA4 A0A182Y1Z7 A0A182RGJ1 A0A182W9C5 A0A182NPD4 A0A0A9YZK2 A0A0K8SA70 A0A0K8S9W9 A0A182IKS5
Ontologies
GO
Topology
Subcellular location
Nucleus
Membrane
Membrane
Length:
606
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.29582
Exp number, first 60 AAs:
0
Total prob of N-in:
0.01411
outside
1 - 606
Population Genetic Test Statistics
Pi
199.874755
Theta
173.024529
Tajima's D
0.651237
CLR
0.278098
CSRT
0.553222338883056
Interpretation
Uncertain
